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gene
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PR:000000374 |
smad7
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SMAD7
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"An inhibitory smad protein that is a translation product of the human SMAD7 gene or a 1:1 ortholog thereof. Smad7 is a negative regulator of TGF-beta signaling." [PMID:17438144]
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organism-gene
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PR:O15105 |
mothers against decapentaplegic homolog 7 (human)
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hSMAD7
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"A smad7 that is encoded in the genome of human." []
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organism-sequence
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PR:O15105-1 |
mothers against decapentaplegic homolog 7 isoform 1 (human)
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hSMAD7/iso:1
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"A smad7 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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Yes |
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organism-modification
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PR:000036565 |
smad7 isoform 1 acetylated 1 (human)
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hSMAD7/iso:1/Ac:1
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"A smad7 isoform 1 acetylated 1 in human. UniProtKB:O15105-1, Lys-64/Lys-70, MOD:00064." [PMID:12408818, PRO:CNA]
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Yes |
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organism-modification
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PR:000036566 |
smad7 isoform 1 phosphorylated 1 (human)
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hSMAD7/iso:1/Phos:1
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"A smad7 isoform 1 phosphorylated 1 in human. UniProtKB:O15105-1, Ser-249, MOD:00046." [PRO:CNA]
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organism-sequence
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PR:O15105-2 |
mothers against decapentaplegic homolog 7 isoform h2 (human)
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hSMAD7/iso:h2
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"A mothers against decapentaplegic homolog 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15105-2." [PRO:DNx, UniProtKB:O15105]
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organism-sequence
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PR:O15105-3 |
mothers against decapentaplegic homolog 7 isoform 3 (human)
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hSMAD7/iso:3
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"A smad7 isoform 3 that is encoded in the genome of human." [PRO:DNx]
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organism-gene
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PR:O35253 |
mothers against decapentaplegic homolog 7 (mouse)
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mSMAD7
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"A smad7 that is encoded in the genome of mouse." [OMA:O35253, PRO:DNx]
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organism-sequence
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PR:O35253-1 |
mothers against decapentaplegic homolog 7 isoform A (mouse)
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mSMAD7/iso:A
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"A smad7 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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organism-modification
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PR:000036932 |
smad7 isoform 1 phosphorylated 1 (mouse)
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mSMAD7/iso:1/Phos:1
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"A smad7 isoform 1 phosphorylated 1 in mouse. UniProtKB:O35253-1, Ser-249, MOD:00046." [PMID:11278814, PRO:CNA]
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Yes |
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organism-modification
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PR:000049801 |
mothers against decapentaplegic homolog 7 isoform A monomethylated 1 (mouse)
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mSMAD7/iso:A/Me1:1
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"A mothers against decapentaplegic homolog 7 isoform A (mouse) that has been monomethylated at the position equivalent to Lys-70. UniProtKB:O35253-1, Lys-70, MOD:00085." [PMID:27292644, PRO:HJD]
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organism-modification
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PR:000049802 |
mothers against decapentaplegic homolog 7 isoform A unmethylated 1 (mouse)
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mSMAD7/iso:A/UnMe:1
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"A mothers against decapentaplegic homolog 7 isoform A (mouse) that lacks a monomethylated Lys at position 70. UniProtKB:O35253-1, Lys-70, PR:000026291." [PMID:27292644, PRO:HJD]
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organism-sequence
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PR:O35253-2 |
mothers against decapentaplegic homolog 7 isoform B (mouse)
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mSMAD7/iso:B
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"A smad7 isoform 3 that is encoded in the genome of mouse." [PRO:DNx]
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organism-gene
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PR:O88406 |
mothers against decapentaplegic homolog 7 (rat)
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rSMAD7
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"A smad7 that is encoded in the genome of rat." [OMA:O88406, PRO:DNx]
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sequence
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PR:000000481 |
smad7 isoform 1
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SMAD7/iso:1
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"A smad7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35253-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
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PR:O15105-1 |
mothers against decapentaplegic homolog 7 isoform 1 (human)
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hSMAD7/iso:1
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"A smad7 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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Yes |
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organism-modification
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PR:000036565 |
smad7 isoform 1 acetylated 1 (human)
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hSMAD7/iso:1/Ac:1
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"A smad7 isoform 1 acetylated 1 in human. UniProtKB:O15105-1, Lys-64/Lys-70, MOD:00064." [PMID:12408818, PRO:CNA]
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Yes |
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organism-modification
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PR:000036566 |
smad7 isoform 1 phosphorylated 1 (human)
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hSMAD7/iso:1/Phos:1
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"A smad7 isoform 1 phosphorylated 1 in human. UniProtKB:O15105-1, Ser-249, MOD:00046." [PRO:CNA]
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organism-sequence
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PR:O35253-1 |
mothers against decapentaplegic homolog 7 isoform A (mouse)
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mSMAD7/iso:A
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"A smad7 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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organism-modification
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PR:000036932 |
smad7 isoform 1 phosphorylated 1 (mouse)
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mSMAD7/iso:1/Phos:1
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"A smad7 isoform 1 phosphorylated 1 in mouse. UniProtKB:O35253-1, Ser-249, MOD:00046." [PMID:11278814, PRO:CNA]
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Yes |
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organism-modification
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PR:000049801 |
mothers against decapentaplegic homolog 7 isoform A monomethylated 1 (mouse)
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mSMAD7/iso:A/Me1:1
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"A mothers against decapentaplegic homolog 7 isoform A (mouse) that has been monomethylated at the position equivalent to Lys-70. UniProtKB:O35253-1, Lys-70, MOD:00085." [PMID:27292644, PRO:HJD]
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organism-modification
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PR:000049802 |
mothers against decapentaplegic homolog 7 isoform A unmethylated 1 (mouse)
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mSMAD7/iso:A/UnMe:1
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"A mothers against decapentaplegic homolog 7 isoform A (mouse) that lacks a monomethylated Lys at position 70. UniProtKB:O35253-1, Lys-70, PR:000026291." [PMID:27292644, PRO:HJD]
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modification
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PR:000000582 |
smad7 isoform 1 acetylated form
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SMAD7/iso:1/AcRes+
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"A smad7 isoform 1 that includes at least one acetylated residue." [PRO:CNA]
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modification
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PR:000000663 |
smad7 isoform 1 acetylated 1
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SMAD7/iso:1/Ac:1
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"A smad7 isoform 1 acetylated form that has been acetylated at Lys residues within the MH1 domain by Histone acetyltransferase p300. Example: UniProtKB:O15105-1, Lys-64/Lys-70, MOD:00064." [PMID:12408818]
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organism-modification
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PR:000036565 |
smad7 isoform 1 acetylated 1 (human)
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hSMAD7/iso:1/Ac:1
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"A smad7 isoform 1 acetylated 1 in human. UniProtKB:O15105-1, Lys-64/Lys-70, MOD:00064." [PMID:12408818, PRO:CNA]
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Yes |
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modification
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PR:000000583 |
smad7 isoform 1 phosphorylated form
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SMAD7/iso:1/PhosRes+
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"A smad7 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
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modification
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PR:000000664 |
smad7 isoform 1 phosphorylated 1
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SMAD7/iso:1/Phos:1
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"A smad7 isoform 1 phosphorylated form in which the phosphorylation occurs at the Ser residue within the DSQL sequence region in the MH2 domain. Example: UniProtKB:O15105-1, Ser-249, MOD:00046." [PRO:CNA]
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organism-modification
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PR:000036566 |
smad7 isoform 1 phosphorylated 1 (human)
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hSMAD7/iso:1/Phos:1
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"A smad7 isoform 1 phosphorylated 1 in human. UniProtKB:O15105-1, Ser-249, MOD:00046." [PRO:CNA]
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organism-modification
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PR:000036932 |
smad7 isoform 1 phosphorylated 1 (mouse)
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mSMAD7/iso:1/Phos:1
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"A smad7 isoform 1 phosphorylated 1 in mouse. UniProtKB:O35253-1, Ser-249, MOD:00046." [PMID:11278814, PRO:CNA]
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Yes |
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modification
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PR:000000584 |
smad7 isoform 1 ubiquitinated form
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SMAD7/iso:1/UbiqLys+
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"A smad7 isoform 1 that includes at least one ubiquitinated lysine." [PRO:CNA]
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modification
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PR:000000665 |
smad7 isoform 1 ubiquitinated 1
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SMAD7/iso:1/Ubiq:1
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"A smad7 isoform 1 ubiquitinated form that has been ubiquitinated at Lys residues within the MH1 domain by Smurf proteins. This targets smad7 for proteosomal degradation." [PMID:12408818]
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sequence
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PR:000038037 |
smad7 isoform 3
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SMAD7/iso:3
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"A smad7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15105-3 or a 1:1 ortholog thereof." [PRO:DNx]
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organism-sequence
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PR:O15105-3 |
mothers against decapentaplegic homolog 7 isoform 3 (human)
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hSMAD7/iso:3
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"A smad7 isoform 3 that is encoded in the genome of human." [PRO:DNx]
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organism-sequence
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PR:O35253-2 |
mothers against decapentaplegic homolog 7 isoform B (mouse)
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mSMAD7/iso:B
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"A smad7 isoform 3 that is encoded in the genome of mouse." [PRO:DNx]
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