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Protein Ontology report - GTP-binding protein RhoA isoform 1
PR:000000395 - http://purl.obolibrary.org/obo/PR_000000395
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000395   
  PRO nameGTP-binding protein RhoA isoform 1 
  Synonyms
PRO-Short-label: EXACT:RHOA/iso:1
  Definition"A GTP-binding protein RhoA that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61586-1 or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorysequence 
  ParentPR:000000176 GTP-binding protein RhoA
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 3                                        
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000395
GTP-binding protein RhoA isoform 1
RHOA/iso:1
"A GTP-binding protein RhoA that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61586-1 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:P61585-1
transforming protein RhoA isoform 1 (cow)
cow-RHOA/iso:1
"A GTP-binding protein RhoA isoform 1 that is encoded in the genome of cow." [PRO:DAN]

organism-modification


PR:000036521
GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1 (cow)
cow-RHOA/iso:1/IpCysEst:1
"A GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1 in cow. UniProtKB:P61585-1, 1-190, Cys-190, MOD:01119." [PMID:1903193, PRO:CNA, PRO:DAN]
Yes
organism-sequence


PR:P61586-1
transforming protein RhoA isoform 1 (human)
hRHOA/iso:1
"A GTP-binding protein RhoA isoform 1 that is encoded in the genome of human." [PRO:CNA]

organism-modification


PR:000036520
GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1 (human)
hRHOA/iso:1/IpCysEst:1
"A GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1 in human. UniProtKB:P61586-1, 1-190, Cys-190, MOD:01119." [PMID:1383236, PMID:16773203, PRO:CNA, PRO:DAN]
Yes
organism-sequence


PR:Q9QUI0-1
transforming protein RhoA isoform 1 (mouse)
mRHOA/iso:1
"A GTP-binding protein RhoA isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

modification


PR:000000615
GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1
RHOA/iso:1/IpCysEst:1
"A GTP-binding protein RhoA isoform 1 that has been geranylgeranylated on the Cys residue within the C-terminal CaaX motif (a=an aliphatic residue, X=any residue), followed by cleavage of aaX and methylation of the Cys. Example: UniProtKB:P61586-1, 1-190, Cys-190, MOD:01119." [PMID:16773203, PMID:1905729, PRO:CNA]

organism-modification


PR:000036520
GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1 (human)
hRHOA/iso:1/IpCysEst:1
"A GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1 in human. UniProtKB:P61586-1, 1-190, Cys-190, MOD:01119." [PMID:1383236, PMID:16773203, PRO:CNA, PRO:DAN]
Yes
organism-modification


PR:000036521
GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1 (cow)
cow-RHOA/iso:1/IpCysEst:1
"A GTP-binding protein RhoA isoform 1 prenylated-cysteine methyl ester-containing 1 in cow. UniProtKB:P61585-1, 1-190, Cys-190, MOD:01119." [PMID:1903193, PRO:CNA, PRO:DAN]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036520 hRHOA/iso:1/IpCysEst:1
UniProtKB:P61586-1, 1-190, Cys-190, MOD:01119		 acts_upstream_of_or_withinGO:0030036 actin cytoskeleton organization PMID:16773203
GO:0043123 positive regulation of canonical NF-kappaB signal transduction PMID:12761501
GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction PMID:12761501
located_inGO:0005886 plasma membrane PMID:16773203
PR:000036521 cow-RHOA/iso:1/IpCysEst:1
UniProtKB:P61585-1, 1-190, Cys-190, MOD:01119		 located_inGO:0005886 plasma membrane PMID:1903193