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Protein Ontology report - growth/differentiation factor 5 isoform 1
PR:000000436 - http://purl.obolibrary.org/obo/PR_000000436
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000436   
  PRO namegrowth/differentiation factor 5 isoform 1 
  Synonyms
PRO-Short-label: EXACT:GDF5/iso:1
  Definition"A growth/differentiation factor 5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43026-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000281 growth/differentiation factor 5
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification2                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000436 growth/differentiation factor 5 isoform 1
GDF5/iso:1

organism-sequence


PR:P43026-1 growth/differentiation factor 5 isoform 1 (human)
hGDF5/iso:1
Yes
organism-modification


PR:000036543 growth/differentiation factor 5 isoform 1 mature form (human)
hGDF5/iso:1/mature
Yes
organism-sequence


PR:P43027-1 growth/differentiation factor 5 isoform 1 (mouse)
mGDF5/iso:1

modification


PR:000021914 growth/differentiation factor 5 isoform 1, signal peptide removed form
GDF5/iso:1/SigPep-

modification


PR:000000640 growth/differentiation factor 5 isoform 1 mature form
GDF5/iso:1/mature

organism-modification


PR:000036543 growth/differentiation factor 5 isoform 1 mature form (human)
hGDF5/iso:1/mature
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036543 hGDF5/iso:1/mature
UniProtKB:P43026-1, 382-501		 enablesGO:0005102 signaling receptor binding PMID:15752764; PMID:15890363
GO:0005515 protein binding PMID:9288098
GO:0008083 growth factor activity PMID:8589725
GO:0042803 protein homodimerization activity PMID:15752764; PMID:8962721
located_inGO:0005615 extracellular space PMID:16532400
PR:P43026-1 hGDF5/iso:1 acts_upstream_of_or_withinGO:0007179 transforming growth factor beta receptor signaling pathway PMID:7961761
GO:0007267 cell-cell signaling PMID:8589725