|
|
 |
|
| | |
| | | | | | | |
sequence
|
|
PR:000000475 |
smad3 isoform 1
|
SMAD3/iso:1
|
"A smad3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P84022-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | |
| | | | | |
organism-sequence
|
|
PR:P84022-1 |
mothers against decapentaplegic homolog 3 isoform 1 (human)
|
hSMAD3/iso:1
|
"A smad3 isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000026333 |
smad3 isoform 1 phosphorylated 1 (human)
|
hSMAD3/iso:1/Phos:1
|
"A smad3 isoform 1 phosphorylated 1 in human. UniProtKB:P84022-1, Ser-423/Ser-425, MOD:00046." [PRO:DNx, UniProtKB:P84022]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000036557 |
smad3 isoform 1 acetylated and phosphorylated 1 (human)
|
hSMAD3/iso:1/AcPhos:1
|
"A smad3 isoform 1 acetylated and phosphorylated 1 in human. UniProtKB:P84022-1, Lys-19, MOD:00064|Ser-423/Ser-425, MOD:00046." [PMID:17074756, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | |
| | | | | |
organism-sequence
|
|
PR:Q8BUN5-1 |
mothers against decapentaplegic homolog 3 isoform 1 (mouse)
|
mSMAD3/iso:1
|
"A smad3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000036558 |
smad3 isoform 1 phosphorylated 1 (mouse)
|
mSMAD3/iso:1/Phos:1
|
"A smad3 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q8BUN5-1, Ser-423/Ser-425, MOD:00046." [PMID:10823886, PMID:12943993, PMID:15282343, PMID:15464984, PMID:9702197, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000036560 |
smad3 isoform 1 phosphorylated 2 (mouse)
|
mSMAD3/iso:1/Phos:2
|
"A smad3 isoform 1 phosphorylated 2 in mouse. UniProtKB:Q8BUN5-1, Thr-8/Thr-179, MOD:00047|Ser-213, MOD:00046." [PMID:15241418, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000036561 |
smad3 isoform 1 phosphorylated 3 (mouse)
|
mSMAD3/iso:1/Phos:3
|
"A smad3 isoform 1 phosphorylated 3 in mouse. UniProtKB:Q8BUN5-1, Thr-179, MOD:00047|Ser-204/Ser-208/Ser-213, MOD:00046." [PMID:10197981, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | |
| | | | | |
modification
|
|
PR:000000577 |
smad3 isoform 1 acetylated and phosphorylated form
|
SMAD3/iso:1/AcPhos+
|
"A smad3 isoform 1 that includes at least one acetylated residue and at least one phosphorylated residue." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | |
modification
|
|
PR:000000657 |
smad3 isoform 1 acetylated and phosphorylated 1
|
SMAD3/iso:1/AcPhos:1
|
"A smad3 isoform 1 acetylated and phosphorylated form in which the phosphorylation occurs upon TGF-beta receptor activation and which has been further acetylated at a Lys residue within the MH1 domain by coactivators, such as CBP and EP300. Example: UniProtKB:P84022-1, Lys-19, MOD:00064|Ser-423/Ser-425, MOD:00046." [PMID:17074756]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000036557 |
smad3 isoform 1 acetylated and phosphorylated 1 (human)
|
hSMAD3/iso:1/AcPhos:1
|
"A smad3 isoform 1 acetylated and phosphorylated 1 in human. UniProtKB:P84022-1, Lys-19, MOD:00064|Ser-423/Ser-425, MOD:00046." [PMID:17074756, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | |
| | | | | |
modification
|
|
PR:000000578 |
smad3 isoform 1 phosphorylated form
|
SMAD3/iso:1/PhosRes+
|
"A smad3 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | |
modification
|
|
PR:000000577 |
smad3 isoform 1 acetylated and phosphorylated form
|
SMAD3/iso:1/AcPhos+
|
"A smad3 isoform 1 that includes at least one acetylated residue and at least one phosphorylated residue." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000000657 |
smad3 isoform 1 acetylated and phosphorylated 1
|
SMAD3/iso:1/AcPhos:1
|
"A smad3 isoform 1 acetylated and phosphorylated form in which the phosphorylation occurs upon TGF-beta receptor activation and which has been further acetylated at a Lys residue within the MH1 domain by coactivators, such as CBP and EP300. Example: UniProtKB:P84022-1, Lys-19, MOD:00064|Ser-423/Ser-425, MOD:00046." [PMID:17074756]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000036557 |
smad3 isoform 1 acetylated and phosphorylated 1 (human)
|
hSMAD3/iso:1/AcPhos:1
|
"A smad3 isoform 1 acetylated and phosphorylated 1 in human. UniProtKB:P84022-1, Lys-19, MOD:00064|Ser-423/Ser-425, MOD:00046." [PMID:17074756, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | |
modification
|
|
PR:000000658 |
smad3 isoform 1 phosphorylated 1
|
SMAD3/iso:1/Phos:1
|
"A smad3 isoform 1 phosphorylated form in which the phosphorylation occurs at the C-terminal SSxS motif as a result of the activation of the transforming growth factor beta signaling pathway. Example: UniProtKB:P84022-1, Ser-423/Ser-425, MOD:00046." [PMID:8774881]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000026333 |
smad3 isoform 1 phosphorylated 1 (human)
|
hSMAD3/iso:1/Phos:1
|
"A smad3 isoform 1 phosphorylated 1 in human. UniProtKB:P84022-1, Ser-423/Ser-425, MOD:00046." [PRO:DNx, UniProtKB:P84022]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000036558 |
smad3 isoform 1 phosphorylated 1 (mouse)
|
mSMAD3/iso:1/Phos:1
|
"A smad3 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q8BUN5-1, Ser-423/Ser-425, MOD:00046." [PMID:10823886, PMID:12943993, PMID:15282343, PMID:15464984, PMID:9702197, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | |
modification
|
|
PR:000000659 |
smad3 isoform 1 phosphorylated 2
|
SMAD3/iso:1/Phos:2
|
"A smad3 isoform 1 phosphorylated form in which the phosphorylation occurs at the N-terminal Px[ST]P motif and the clusters of [ST]P motifs within the MH1-MH2 domain linker region by G1 cyclin-dependent kinases (CDK4 and CDK2) leading to CDK inhibition of its transcriptional activity and antiproliferative function. Example: UniProtKB:Q8BUN5-1, Thr-8/Thr-179, MOD:00047|Ser-213, MOD:00046." [PMID:15241418, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000036560 |
smad3 isoform 1 phosphorylated 2 (mouse)
|
mSMAD3/iso:1/Phos:2
|
"A smad3 isoform 1 phosphorylated 2 in mouse. UniProtKB:Q8BUN5-1, Thr-8/Thr-179, MOD:00047|Ser-213, MOD:00046." [PMID:15241418, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | |
modification
|
|
PR:000000660 |
smad3 isoform 1 phosphorylated 3
|
SMAD3/iso:1/Phos:3
|
"A smad3 isoform 1 phosphorylated form in which the phosphorylation occurs at the clusters of [S/T]P motifs within the MH1-MH2 domain linker region through the MAP kinase cascade in oncogenic Ras-activated pathway. Example: UniProtKB:Q8BUN5-1, Thr-179, MOD:00047|Ser-204/Ser-208/Ser-213, MOD:00046." [PMID:10197981, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000036561 |
smad3 isoform 1 phosphorylated 3 (mouse)
|
mSMAD3/iso:1/Phos:3
|
"A smad3 isoform 1 phosphorylated 3 in mouse. UniProtKB:Q8BUN5-1, Thr-179, MOD:00047|Ser-204/Ser-208/Ser-213, MOD:00046." [PMID:10197981, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
