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Protein Ontology report - smad5 isoform 1
PR:000000477 - http://purl.obolibrary.org/obo/PR_000000477
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000477   
  PRO namesmad5 isoform 1 
  Synonyms
PRO-Short-label: EXACT:SMAD5/iso:1
  Definition"A smad5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99717-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000372 smad5
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000477 smad5 isoform 1
SMAD5/iso:1

organism-sequence


PR:P97454-1 mothers against decapentaplegic homolog 5 isoform 1 (mouse)
mSMAD5/iso:1
Yes
organism-modification


PR:000036563 smad5 isoform 1 phosphorylated 1 (mouse)
mSMAD5/iso:1/Phos:1
Yes
organism-sequence


PR:Q99717-1 mothers against decapentaplegic homolog 5 isoform 1 (human)
hSMAD5/iso:1
Yes
organism-modification


PR:000036562 smad5 isoform 1 phosphorylated 1 (human)
hSMAD5/iso:1/Phos:1
Yes
modification


PR:000000580 smad5 isoform 1 phosphorylated form
SMAD5/iso:1/PhosRes+

modification


PR:000000661 smad5 isoform 1 phosphorylated 1
SMAD5/iso:1/Phos:1

organism-modification


PR:000036562 smad5 isoform 1 phosphorylated 1 (human)
hSMAD5/iso:1/Phos:1
Yes
organism-modification


PR:000036563 smad5 isoform 1 phosphorylated 1 (mouse)
mSMAD5/iso:1/Phos:1
Yes
modification


PR:000026652 smad5 isoform 1, initiator methionine removed form
SMAD5/iso:1/InitMet-

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0007165 signal transductionPR:P97454-1 mSMAD5/iso:1 PMID:16765933
GO:0030509 BMP signaling pathwayPR:000036562 hSMAD5/iso:1/Phos:1 PMID:8637600
PR:000036563 mSMAD5/iso:1/Phos:1 PMID:16522160
PR:P97454-1 mSMAD5/iso:1 PMID:16522160; PMID:16765933
PR:Q99717-1 hSMAD5/iso:1 PMID:8673135

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specificPR:000036562 hSMAD5/iso:1/Phos:1 PMID:8673135
PR:Q99717-1 hSMAD5/iso:1 PMID:8673135

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005634 nucleusPR:000036563 mSMAD5/iso:1/Phos:1 PMID:10504300; PMID:9759503
GO:0005737 cytoplasmPR:P97454-1 mSMAD5/iso:1 PMID:10504300