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PRO ID
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| PRO name | Rho-associated protein kinase 1 isoform 1 cleaved 1 |
| Synonyms | | PRO-Short-label: | EXACT: | ROCK1/iso:1/Clv:1 | | Other: | EXACT: | constitutively active ROCK-1 |
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| Definition | "A Rho-associated protein kinase 1 isoform 1 that has been processed by caspase-3 downstream the sequence motif DETD, removing the inhibitory C-terminus." [PMID:11283607, PMID:16983089] |
| Comment | Note: This form has been found significantly elevated in mouse myopathy model and human heart failure patients. |
| PRO Category | modification |
| Parent | PR:000000307 Rho-associated protein kinase 1 isoform 1
PR:000025435 Rho-associated protein kinase 1 proteolytic cleavage product
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| Terms by PRO Category |
| Organism-Independent |
Organism-Specific |
| Category |
Number of Terms |
Category |
Number of Terms | | Modification | 1 |
Organism-Modification |
2 | | | |
Term Hierarchy
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