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Protein Ontology report - Rho-associated protein kinase 2 isoform 1 cleaved 1
PR:000000564 - http://purl.obolibrary.org/obo/PR_000000564
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000564   
  PRO nameRho-associated protein kinase 2 isoform 1 cleaved 1 
  Synonyms
PRO-Short-label: EXACT:ROCK2/iso:1/Clv:1
  Definition"A Rho-associated protein kinase 2 isoform 1 that has been cleaved in the granzyme B consensus motif [IVL][GE]xD located between the Rho binding and the PH domains, removing the C-terminus." [PRO:CNA] 
  CommentNote: This form has constitutive kinase activity. 
  PRO Categorymodification 
  ParentPR:000000308 Rho-associated protein kinase 2 isoform 1
PR:000025436 Rho-associated protein kinase 2 proteolytic cleavage product
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000000564 Rho-associated protein kinase 2 isoform 1 cleaved 1
ROCK2/iso:1/Clv:1

organism-modification


PR:000036477 Rho-associated protein kinase 2 isoform 1 cleaved 1 (human)
hROCK2/iso:1/Clv:1
Yes
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0006468 protein phosphorylationPR:000036477 hROCK2/iso:1/Clv:1 PMID:15699075
GO:0030036 actin cytoskeleton organizationPR:000036477 hROCK2/iso:1/Clv:1 PMID:15699075

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0004674 protein serine/threonine kinase activityPR:000036477 hROCK2/iso:1/Clv:1 PMID:15699075

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005622 intracellular anatomical structurePR:000036477 hROCK2/iso:1/Clv:1 PMID:15699075