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RACE-PRO
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Protein Ontology report - transcription factor Sp1 isoform 1 phosphorylated 3
PR:000000601 -
http://purl.obolibrary.org/obo/PR_000000601
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000601
PRO name
transcription factor Sp1 isoform 1 phosphorylated 3
Synonyms
PRO-Short-label
:
EXACT:
SP1/iso:1/Phos:3
Definition
"A transcription factor Sp1 isoform 1 phosphorylated form in which the phosphorylation occurs at the Ser residue within the CyclinA/cdk2 phosphorylation site (QPSP sequence). Phosphorylation at this site induces removal of the inhibitory domain by proteolytic processing and activation of transcription activity. Example:
UniProtKB:P08047-1
, Ser-59,
MOD:00046
." [
PMID:18239466
]
PRO Category
modification
Parent
PR:000000493
transcription factor Sp1 isoform 1 phosphorylated form
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000000601
transcription factor Sp1 isoform 1 phosphorylated 3
SP1/iso:1/Phos:3
"A transcription factor Sp1 isoform 1 phosphorylated form in which the phosphorylation occurs at the Ser residue within the CyclinA/cdk2 phosphorylation site (QPSP sequence). Phosphorylation at this site induces removal of the inhibitory domain by proteolytic processing and activation of transcription activity. Example: UniProtKB:P08047-1, Ser-59, MOD:00046." [PMID:18239466]
organism-modification
PR:000036501
transcription factor Sp1 isoform 1 phosphorylated 3 (human)
hSP1/iso:1/Phos:3
"A transcription factor Sp1 isoform 1 phosphorylated 3 in human. UniProtKB:P08047-1, Ser-59, MOD:00046." [PMID:17049555, PMID:18239466, PRO:CNA]
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036501
hSP1/iso:1/Phos:3
UniProtKB:P08047-1, Ser-59, MOD:00046
enables
increased
GO:0003700
DNA-binding transcription factor activity
relative to
PR:000036497
hSP1/iso:1/Clv:1
PMID:17049555
;
PMID:18239466
located_in
GO:0005634
nucleus
PMID:17049555
;
PMID:18239466