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RACE-PRO
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Documentation
Protein Ontology report - TGF-beta 2 isoform A cleaved 1
PR:000000629 -
http://purl.obolibrary.org/obo/PR_000000629
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000629
PRO name
TGF-beta 2 isoform A cleaved 1
Synonyms
PRO-Short-label
:
EXACT:
TGFB2/iso:A/Clv:1
Other
:
RELATED:
TGF-beta 2 mature protein
Definition
"A TGF-beta 2 isoform A that has been processed by proteolytic cleavage and released from the latent complex. This form, cross-linked to an identical chain, is the active mature protein." [
PMID:3476488
]
PRO Category
modification
Parent
PR:000000404
TGF-beta 2 isoform A
PR:000018293
TGF-beta 2 proteolytic cleavage product
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Short Name
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000000629
TGF-beta 2 isoform A cleaved 1
TGFB2/iso:A/Clv:1
organism-modification
PR:000036530
TGF-beta 2 isoform A cleaved 1 (human)
hTGFB2/iso:A/Clv:1
Yes
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Functional Annotation (GO-centric view)
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PRO Centric View
Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0007179
transforming growth factor beta receptor signaling pathway
PR:000036530
hTGFB2/iso:A/Clv:1
PMID:3162913
GO:0008285
negative regulation of cell population proliferation
PR:000036530
hTGFB2/iso:A/Clv:1
PMID:15944186
Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0001540
amyloid-beta binding
PR:000036530
hTGFB2/iso:A/Clv:1
PMID:16227582
GO:0005160
transforming growth factor beta receptor binding
PR:000036530
hTGFB2/iso:A/Clv:1
PMID:16227582
GO:0042803
protein homodimerization activity
PR:000036530
hTGFB2/iso:A/Clv:1
PMID:2119582
;
PMID:3476488
Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005615
extracellular space
PR:000036530
hTGFB2/iso:A/Clv:1
PMID:3162913
