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Protein Ontology report - activin/inhibin beta A chain isoform 1 mature form
PR:000000637 -
http://purl.obolibrary.org/obo/PR_000000637
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000637
PRO name
activin/inhibin beta A chain isoform 1 mature form
Synonyms
PRO-Short-label
:
EXACT:
INHBA/iso:1/mature
Definition
"An activin/inhibin beta A chain isoform 1, signal peptide removed form that has been processed by subsequent removal of the propeptide. It is a subunit of inhibin A and activin A complexes. Inhibin A complex is a dimer of INHA and INHBA, whereas activin A complex is a homodimer of INHBA." [
PMID:15948132
]
PRO Category
modification
Parent
PR:000021911
activin/inhibin beta A chain isoform 1, signal peptide removed form
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000000637
activin/inhibin beta A chain isoform 1 mature form
INHBA/iso:1/mature
"An activin/inhibin beta A chain isoform 1, signal peptide removed form that has been processed by subsequent removal of the propeptide. It is a subunit of inhibin A and activin A complexes. Inhibin A complex is a dimer of INHA and INHBA, whereas activin A complex is a homodimer of INHBA." [PMID:15948132]
organism-modification
PR:000036539
activin/inhibin beta A chain isoform 1 mature form (mouse)
mINHBA/iso:1/mature
"An activin/inhibin beta A chain isoform 1 mature form in mouse. UniProtKB:Q04998-1, 309-424." [PMID:1646080, PMID:2133547, PMID:7577669, PRO:CNA]
Yes
organism-modification
PR:000036540
activin/inhibin beta A chain isoform 1 mature form (human)
hINHBA/iso:1/mature
"An activin/inhibin beta A chain isoform 1 mature form in human. UniProtKB:P08476-1, 311-426." [PMID:10320815, PMID:12213882, PMID:12456957, PMID:12960042, PMID:1537316, PMID:17456790, PMID:2575216, PMID:7890768, PMID:9884026, PRO:CNA]
Yes
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Functional Annotation (GO-centric view)
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PRO Centric View
Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0007166
cell surface receptor signaling pathway
PR:000036540
hINHBA/iso:1/mature
PMID:12456957
GO:0007267
cell-cell signaling
PR:000036540
hINHBA/iso:1/mature
PMID:12456957
GO:0009605
response to external stimulus
PR:000036540
hINHBA/iso:1/mature
PMID:10320815
GO:0030154
cell differentiation
PR:000036540
hINHBA/iso:1/mature
PMID:12456957
GO:0032925
regulation of activin receptor signaling pathway
PR:000036540
hINHBA/iso:1/mature
PMID:9884026
Molecular Function GO Term
Protein Forms & Complexes
Evidence
contributes_to
GO:0005102
signaling receptor binding
PR:000036539
mINHBA/iso:1/mature
PMID:1646080
;
PMID:7577669
PR:000036540
hINHBA/iso:1/mature
PMID:7890768
GO:0046983
protein dimerization activity
PR:000036539
mINHBA/iso:1/mature
PMID:2133547
PR:000036540
hINHBA/iso:1/mature
PMID:1537316
Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005576
extracellular region
PR:000036540
hINHBA/iso:1/mature
PMID:12213882
;
PMID:2575216
GO:0032991
protein-containing complex
PR:000036540
hINHBA/iso:1/mature
PMID:12960042
GO:0043509
activin A complex
PR:000036540
hINHBA/iso:1/mature
PMID:7890768
GO:0043512
inhibin A complex
PR:000036540
hINHBA/iso:1/mature
PMID:17456790
;
PMID:7890768