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Protein Ontology report - activin/inhibin beta A chain isoform 1 mature form
PR:000000637 - http://purl.obolibrary.org/obo/PR_000000637
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000637   
  PRO nameactivin/inhibin beta A chain isoform 1 mature form 
  Synonyms
PRO-Short-label: EXACT:INHBA/iso:1/mature
  Definition"An activin/inhibin beta A chain isoform 1, signal peptide removed form that has been processed by subsequent removal of the propeptide. It is a subunit of inhibin A and activin A complexes. Inhibin A complex is a dimer of INHA and INHBA, whereas activin A complex is a homodimer of INHBA." [PMID:15948132
  PRO Categorymodification 
  ParentPR:000021911 activin/inhibin beta A chain isoform 1, signal peptide removed form
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
modification



PR:000000637

activin/inhibin beta A chain isoform 1 mature form

INHBA/iso:1/mature


"An activin/inhibin beta A chain isoform 1, signal peptide removed form that has been processed by subsequent removal of the propeptide. It is a subunit of inhibin A and activin A complexes. Inhibin A complex is a dimer of INHA and INHBA, whereas activin A complex is a homodimer of INHBA." [PMID:15948132]


organism-modification



PR:000036539

activin/inhibin beta A chain isoform 1 mature form (mouse)

mINHBA/iso:1/mature


"An activin/inhibin beta A chain isoform 1 mature form in mouse. UniProtKB:Q04998-1, 309-424." [PMID:1646080, PMID:2133547, PMID:7577669, PRO:CNA]

Yes

organism-modification



PR:000036540

activin/inhibin beta A chain isoform 1 mature form (human)

hINHBA/iso:1/mature


"An activin/inhibin beta A chain isoform 1 mature form in human. UniProtKB:P08476-1, 311-426." [PMID:10320815, PMID:12213882, PMID:12456957, PMID:12960042, PMID:1537316, PMID:17456790, PMID:2575216, PMID:7890768, PMID:9884026, PRO:CNA]

Yes

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0007166 cell surface receptor signaling pathwayPR:000036540 hINHBA/iso:1/mature PMID:12456957
GO:0007267 cell-cell signalingPR:000036540 hINHBA/iso:1/mature PMID:12456957
GO:0009605 response to external stimulusPR:000036540 hINHBA/iso:1/mature PMID:10320815
GO:0030154 cell differentiationPR:000036540 hINHBA/iso:1/mature PMID:12456957
GO:0032925 regulation of activin receptor signaling pathwayPR:000036540 hINHBA/iso:1/mature PMID:9884026

Molecular Function GO Term

Protein Forms & Complexes

Evidence
contributes_to GO:0005102 signaling receptor bindingPR:000036539 mINHBA/iso:1/mature PMID:1646080; PMID:7577669
PR:000036540 hINHBA/iso:1/mature PMID:7890768
GO:0046983 protein dimerization activityPR:000036539 mINHBA/iso:1/mature PMID:2133547
PR:000036540 hINHBA/iso:1/mature PMID:1537316

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0005576 extracellular regionPR:000036540 hINHBA/iso:1/mature PMID:12213882; PMID:2575216
GO:0032991 protein-containing complexPR:000036540 hINHBA/iso:1/mature PMID:12960042
GO:0043509 activin A complexPR:000036540 hINHBA/iso:1/mature PMID:7890768
GO:0043512 inhibin A complexPR:000036540 hINHBA/iso:1/mature PMID:17456790; PMID:7890768