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RACE-PRO
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Documentation
Protein Ontology report - lefty 1 isoform 1 cleaved 1
PR:000000643 -
http://purl.obolibrary.org/obo/PR_000000643
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000643
PRO name
lefty 1 isoform 1 cleaved 1
Synonyms
PRO-Short-label
:
EXACT:
LEFTY1/iso:1/Clv:1
Definition
"A lefty 1 isoform 1 that is the C-terminal part after processing by proteolytic cleavage at the first dibasic RxxR cleavage site within the propeptide region." [
PMID:11278322
,
PMID:18039650
]
PRO Category
modification
Parent
PR:000000450
lefty 1 isoform 1
PR:000025431
lefty 1 proteolytic cleavage product
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Short Name
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000000643
lefty 1 isoform 1 cleaved 1
LEFTY1/iso:1/Clv:1
organism-modification
PR:000036546
lefty 1 isoform 1 cleaved 1 (human)
hLEFTY1/iso:1/Clv:1
Yes
organism-modification
PR:000036547
lefty 1 isoform 1 cleaved 1 (mouse)
mLEFTY1/iso:1/Clv:1
Yes
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Functional Annotation (GO-centric view)
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PRO Centric View
Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0008285
negative regulation of cell population proliferation
PR:000036547
mLEFTY1/iso:1/Clv:1
PMID:15004567
GO:0009948
anterior/posterior axis specification
PR:000036547
mLEFTY1/iso:1/Clv:1
PMID:15004567
Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005615
extracellular space
PR:000036546
hLEFTY1/iso:1/Clv:1
PMID:11278322
PR:000036547
mLEFTY1/iso:1/Clv:1
PMID:18039650