Home
|
Linked Open Data
|
Browse
|
Search
|
Statistics
|
Download
RACE-PRO
PRO tracker
Community
PRO Consortium
Publications
Documentation
Protein Ontology report - smad2 isoform Short phosphorylated 1
PR:000000656 -
http://purl.obolibrary.org/obo/PR_000000656
Protein Forms
Complex
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000656
PRO name
smad2 isoform Short phosphorylated 1
Synonyms
PRO-Short-label
:
EXACT:
SMAD2/iso:Short/Phos:1
Other
:
RELATED:
TGF-beta receptor-activated smad2
Definition
"A smad2 isoform Short phosphorylated form in which the phosphorylation occurs at the last two Ser residues within the SSxS C-terminal motif by TGF-beta pathway activation. Example:
UniProtKB:Q15796-2
, Ser-435/Ser-437,
MOD:00046
." [
PMID:15630024
,
PMID:17074756
,
PMID:9873005
]
PRO Category
modification
Parent
PR:000000576
smad2 isoform Short phosphorylated form
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
Back to top
Protein Forms
Switch to
Extended View
Category
PRO Form Name
Short Name
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000000656
smad2 isoform Short phosphorylated 1
SMAD2/iso:Short/Phos:1
Yes
organism-modification
PR:000025938
smad2 isoform Short phosphorylated 1 (human)
hSMAD2/iso:Short/Phos:1
Yes
Yes
organism-modification
PR:000025943
smad2 isoform Short phosphorylated 1 (mouse)
mSMAD2/iso:Short/Phos:1
Yes
Yes
Back to top
SMAD2/iso:Short/Phos:1
forms found in complexes
SMAD2/iso:Short/Phos:1
Component
Complexes
PR:000000656
SMAD2/iso:Short/Phos:1
PR:000025968
smad2-smad4 protein complex 2
PR:000025938
hSMAD2/iso:Short/Phos:1
PR:000025940
smad2-smad4 protein complex 2 (human)
PR:000025943
mSMAD2/iso:Short/Phos:1
PR:000025945
smad2-smad4 protein complex 2 (mouse)
Back to top
Functional Annotation (GO-centric view)
Switch to
PRO Centric View
Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0007179
transforming growth factor beta receptor signaling pathway
PR:000025938
hSMAD2/iso:Short/Phos:1
PMID:9873005
PR:000025943
mSMAD2/iso:Short/Phos:1
PMID:15630024
Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0003677
DNA binding
PR:000025938
hSMAD2/iso:Short/Phos:1
PMID:14701940
;
PMID:9873005
GO:0003700
DNA-binding transcription factor activity
PR:000025938
hSMAD2/iso:Short/Phos:1
PMID:9873005
PR:000025943
mSMAD2/iso:Short/Phos:1
PMID:15630024
GO:0003712
transcription coregulator activity
PR:000025938
hSMAD2/iso:Short/Phos:1
PMID:14701940
;
PMID:9873005
