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gene
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PR:000000671 |
cation channel sperm-associated protein 3
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CATSPER3
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"A CatSper channel protein that is a translation product of the human CATSPER3 gene or a 1:1 ortholog thereof. In mammals, four CatSper ion channel subunit genes (CatSpers 1-4) are required for sperm cell hyperactivation and male fertility. The four proteins assemble (presumably as a tetramer) to form a sperm-specific, alkalinization-activated Ca(2+)-selective channel. CatSper channels seem to require auxiliary subunits, such as CatSperB (PR:000000672). In common with other channels, CatSper3 proteins have an architecture consisting of six transmembrane domains (S1-S6), arranged in a voltage sensor (S1-S4) and pore modules (S5-P-S6), and with both N and C termini on the intracellular side of the membrane." [PRO:CNA]
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organism-gene
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PR:Q80W99 |
cation channel sperm-associated protein 3 (mouse)
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mCATSPER3
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"A cation channel sperm-associated protein 3 that is encoded in the genome of mouse." [OMA:Q80W99, PRO:DNx]
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Yes |
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organism-sequence
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PR:Q80W99-1 |
cation channel sperm-associated protein 3 isoform 1 (mouse)
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mCATSPER3/iso:1
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"A cation channel sperm-associated protein 3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
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organism-sequence
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PR:Q80W99-2 |
cation channel sperm-associated protein 3 isoform 2 (mouse)
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mCATSPER3/iso:2
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"A cation channel sperm-associated protein 3 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
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organism-gene
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PR:Q86XQ3 |
cation channel sperm-associated protein 3 (human)
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hCATSPER3
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"A cation channel sperm-associated protein 3 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q86XQ3]
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organism-sequence
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PR:Q86XQ3-1 |
cation channel sperm-associated protein 3 isoform 1 (human)
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hCATSPER3/iso:1
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"A cation channel sperm-associated protein 3 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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sequence
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PR:000000693 |
cation channel sperm-associated protein 3 isoform 1
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CATSPER3/iso:1
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"A cation channel sperm-associated protein 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80W99-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
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PR:Q80W99-1 |
cation channel sperm-associated protein 3 isoform 1 (mouse)
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mCATSPER3/iso:1
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"A cation channel sperm-associated protein 3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
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organism-sequence
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PR:Q86XQ3-1 |
cation channel sperm-associated protein 3 isoform 1 (human)
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hCATSPER3/iso:1
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"A cation channel sperm-associated protein 3 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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sequence
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PR:000000694 |
cation channel sperm-associated protein 3 isoform 2
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CATSPER3/iso:2
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"A cation channel sperm-associated protein 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80W99-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
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PR:Q80W99-2 |
cation channel sperm-associated protein 3 isoform 2 (mouse)
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mCATSPER3/iso:2
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"A cation channel sperm-associated protein 3 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
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