back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - cation channel sperm-associated auxiliary subunit beta
PR:000000672 - http://purl.obolibrary.org/obo/PR_000000672
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000672   
  PRO namecation channel sperm-associated auxiliary subunit beta 
  Synonyms
PRO-Short-label: EXACT:CATSPERB
Gene-based: RELATED:C14orf161
Other: EXACT:CatSper-beta
  Definition"A protein that is a translation product of the human CATSPERB gene or a 1:1 ortholog thereof. Members of this class are auxiliary proteins to the CatSper channel. They have four putative transmembrane-spanning domains. In mammals, four CatSper ion channel subunit genes (CatSpers 1-4) are required for sperm cell hyperactivation and male fertility. The four proteins assemble (presumably as a tetramer) to form a sperm-specific, alkalinization-activated Ca(2+)-selective channel." [PMID:17478420, PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence1                                                  Organism-Sequence 3                                        
         Modification1                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
PIRSF:PIRSF038543
Back to top
Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000000672

cation channel sperm-associated auxiliary subunit beta

CATSPERB


"A protein that is a translation product of the human CATSPERB gene or a 1:1 ortholog thereof. Members of this class are auxiliary proteins to the CatSper channel. They have four putative transmembrane-spanning domains. In mammals, four CatSper ion channel subunit genes (CatSpers 1-4) are required for sperm cell hyperactivation and male fertility. The four proteins assemble (presumably as a tetramer) to form a sperm-specific, alkalinization-activated Ca(2+)-selective channel." [PMID:17478420, PRO:CNA]


organism-gene



PR:A2RTF1

cation channel sperm-associated auxiliary subunit beta (mouse)

mCATSPERB


"A cation channel sperm-associated auxiliary subunit beta that is encoded in the genome of mouse." [OMA:A2RTF1, PRO:DNx]


organism-sequence



PR:A2RTF1-1

cation channel sperm-associated auxiliary subunit beta isoform 1 (mouse)

mCATSPERB/iso:1


"A cation channel sperm-associated auxiliary subunit beta isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-gene



PR:Q9H7T0

cation channel sperm-associated auxiliary subunit beta (human)

hCATSPERB


"A cation channel sperm-associated auxiliary subunit beta that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9H7T0]


organism-sequence



PR:Q9H7T0-1

cation channel sperm-associated auxiliary subunit beta isoform 1 (human)

hCATSPERB/iso:1


"A cation channel sperm-associated auxiliary subunit beta isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q9H7T0-2

cation channel sperm-associated auxiliary subunit beta isoform h2 (human)

hCATSPERB/iso:h2


"A cation channel sperm-associated auxiliary subunit beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H7T0-2." [PRO:DNx, UniProtKB:Q9H7T0]


sequence



PR:000000695

cation channel sperm-associated auxiliary subunit beta isoform 1

CATSPERB/iso:1


"A cation channel sperm-associated auxiliary subunit beta that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H7T0-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:A2RTF1-1

cation channel sperm-associated auxiliary subunit beta isoform 1 (mouse)

mCATSPERB/iso:1


"A cation channel sperm-associated auxiliary subunit beta isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-sequence



PR:Q9H7T0-1

cation channel sperm-associated auxiliary subunit beta isoform 1 (human)

hCATSPERB/iso:1


"A cation channel sperm-associated auxiliary subunit beta isoform 1 that is encoded in the genome of human." [PRO:CNA]


modification



PR:000002588

cation channel sperm-associated auxiliary subunit beta isoform 1 unmodified form

CATSPERB/iso:1/UnMod


"A cation channel sperm-associated auxiliary subunit beta isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]


Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:A2RTF1-1 mCATSPERB/iso:1 located_inGO:0032991 protein-containing complex PMID:17478420