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Protein Ontology report - shab-related voltage-gated potassium channel alpha subunit
PR:000000677 - http://purl.obolibrary.org/obo/PR_000000677
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000677   
  PRO nameshab-related voltage-gated potassium channel alpha subunit 
  Synonyms
PRO-Short-label: EXACT:fam:Kchan_shab_sub-a
Other: RELATED:Kv2 channel
  Definition"A voltage-gated potassium channel protein that has a conserved carboxyl-terminal domain called the Kv2 channel domain. Kv2 channels are known as delayed rectifier channels. Shab-related voltage-potassium channels are involved in maintaining membrane potential and modulating electrical excitability in neurons. In common with other voltage-gated channels, has a domain composition consisting of six transmembrane domains (S1-S6), arranged in a voltage sensor (S1-S4) and pore modules (S5-P-S6), and with both N and C termini on the intracellular side of the membrane. The charged S4 segment with a basic amino acid at every third position confers their voltage sensitivity. In common with Kv3 and Kv4 channels, the tetramerization domain at the N terminus contains a zinc binding site." [PRO:CNA] 
  PRO Categoryfamily 
  ParentPR:000044654 voltage-gated potassium channel protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene2                                                  Organism-Gene 6                                        
         Sequence2                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF038520
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000000677 shab-related voltage-gated potassium channel alpha subunit
fam:Kchan_shab_sub-a

gene


PR:000000722 voltage-gated potassium channel KCNB1
KCNB1

organism-gene


PR:P15387 potassium voltage-gated channel subfamily B member 1 (rat)
rKCNB1

organism-gene


PR:Q03717 potassium voltage-gated channel subfamily B member 1 (mouse)
mKCNB1

organism-sequence


PR:Q03717-1 potassium voltage-gated channel subfamily B member 1 isoform 1 (mouse)
mKCNB1/iso:1

organism-gene


PR:Q14721 potassium voltage-gated channel subfamily B member 1 (human)
hKCNB1

organism-sequence


PR:Q14721-1 potassium voltage-gated channel subfamily B member 1 isoform 1 (human)
hKCNB1/iso:1

sequence


PR:000000779 voltage-gated potassium channel KCNB1 isoform 1
KCNB1/iso:1

organism-sequence


PR:Q03717-1 potassium voltage-gated channel subfamily B member 1 isoform 1 (mouse)
mKCNB1/iso:1

organism-sequence


PR:Q14721-1 potassium voltage-gated channel subfamily B member 1 isoform 1 (human)
hKCNB1/iso:1

gene


PR:000000723 voltage-gated potassium channel KCNB2
KCNB2

organism-gene


PR:A6H8H5 potassium voltage-gated channel subfamily B member 2 (mouse)
mKCNB2

organism-gene


PR:Q63099 potassium voltage-gated channel subfamily B member 2 (rat)
rKCNB2

organism-gene


PR:Q92953 potassium voltage-gated channel subfamily B member 2 (human)
hKCNB2

organism-sequence


PR:Q92953-1 potassium voltage-gated channel subfamily B member 2 isoform 1 (human)
hKCNB2/iso:1
Yes
organism-modification


PR:000085101 potassium voltage-gated channel subfamily B member 2 cysteinylated 1 (human)
hKCNB2/Cyst:1

sequence


PR:000000780 voltage-gated potassium channel KCNB2 isoform 1
KCNB2/iso:1

organism-sequence


PR:Q92953-1 potassium voltage-gated channel subfamily B member 2 isoform 1 (human)
hKCNB2/iso:1
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q92953-1 hKCNB2/iso:1 acts_upstream_of_or_withinGO:0006940 regulation of smooth muscle contraction PMID:9612272
enablescontributes_to GO:0005251 delayed rectifier potassium channel activity PMID:9612272