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Protein Ontology report - transient receptor potential cation channel TRPC
PR:000000680 - http://purl.obolibrary.org/obo/PR_000000680
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000680   
  PRO nametransient receptor potential cation channel TRPC 
  Synonyms
PRO-Short-label: EXACT:fam:TRPC
  Definition"A transient receptor potential channel protein that is a member of the subfamily C of the transient receptor potential cation channels (TRPs), with amino- and carboxyl-terminal intracellular domains separated by a domain (common with other ion channels) containing six transmembrane helices (S1-S6) in which the last two helices (S5 and S6) flank a loop, called the pore loop, which determines ion selectivity. The amino-terminal domain contains up to 4 detectable copies of Ankyrin repeat (Pfam:PF00023) followed by the Transient receptor ion channel II domain (Pfam:PF08344). Most TRPs are relatively non-selective. They may be modulated by voltage changes but channel gating is generally effected by other means." [PMID:16382100, PMID:16460286, PMID:17579562, PRO:WCB] 
  PRO Categoryfamily 
  ParentPR:000044657 transient receptor potential channel protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family3                                                  Organism-Family 0                                        
         Gene7                                                  Organism-Gene 17                                        
         Sequence12                                                  Organism-Sequence 31                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF005528
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000000680

transient receptor potential cation channel TRPC

fam:TRPC


"A transient receptor potential channel protein that is a member of the subfamily C of the transient receptor potential cation channels (TRPs), with amino- and carboxyl-terminal intracellular domains separated by a domain (common with other ion channels) containing six transmembrane helices (S1-S6) in which the last two helices (S5 and S6) flank a loop, called the pore loop, which determines ion selectivity. The amino-terminal domain contains up to 4 detectable copies of Ankyrin repeat (Pfam:PF00023) followed by the Transient receptor ion channel II domain (Pfam:PF08344). Most TRPs are relatively non-selective. They may be modulated by voltage changes but channel gating is generally effected by other means." [PMID:16382100, PMID:16460286, PMID:17579562, PRO:WCB]


family



PR:000000718

transient receptor potential cation channel TRPC3/6/7

fam:TRPC[3/6/7]


"A transient receptor potential cation channel TRPC that is a member of a subgroup of subfamily C containing the very similar TRPC3, TRPC6, and TRPC7. They form homomeric or heteromeric nonselective cation channels that generate double-rectifying currents and are activated by diacylglycerol." [PMID:16382100, PMID:16460286, PMID:17579562]


gene



PR:000000775

short transient receptor potential cation channel TRPC3

TRPC3


"A transient receptor potential cation channel TRPC3/6/7 that is a translation product of the human TRPC3 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P34586

transient-receptor-potential-like protein (worm)

TRPC3 (worm)


"A short transient receptor potential cation channel TRPC3 that is encoded in the genome of worm." [PRO:CNA]


organism-gene



PR:Q13507

short transient receptor potential channel 3 (human)

hTRPC3


"A short transient receptor potential cation channel TRPC3 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q13507]


organism-sequence



PR:Q13507-1

short transient receptor potential channel 3 isoform 1 (human)

hTRPC3/iso:1


"A short transient receptor potential cation channel TRPC3 isoform 1 that is encoded in the genome of human." [PRO:HJD]

Yes

organism-sequence



PR:Q13507-2

short transient receptor potential channel 3 isoform h1 (human)

hTRPC3/iso:h1


"A short transient receptor potential channel 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13507-2." [PRO:DNx, UniProtKB:Q13507]


organism-sequence



PR:Q13507-3

short transient receptor potential channel 3 isoform h2 (human)

hTRPC3/iso:h2


"A short transient receptor potential channel 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13507-3." [PRO:DNx, UniProtKB:Q13507]


organism-gene



PR:Q9JMI9

short transient receptor potential channel 3 (rat)

rTRPC3


"A short transient receptor potential cation channel TRPC3 that is encoded in the genome of rat." [OMA:Q9JMI9, PRO:DNx]


organism-gene



PR:Q9QZC1

short transient receptor potential channel 3 (mouse)

mTRPC3


"A short transient receptor potential cation channel TRPC3 that is encoded in the genome of mouse." [OMA:Q9QZC1, PRO:DNx]


sequence



PR:000000937

short transient receptor potential cation channel TRPC3 isoform 1

TRPC3/iso:1


"A short transient receptor potential cation channel TRPC3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13507-1 or a 1:1 ortholog thereof." [PRO:DAN, PRO:HJD]


organism-sequence



PR:Q13507-1

short transient receptor potential channel 3 isoform 1 (human)

hTRPC3/iso:1


"A short transient receptor potential cation channel TRPC3 isoform 1 that is encoded in the genome of human." [PRO:HJD]

Yes

gene



PR:000001080

short transient receptor potential cation channel TRPC7

TRPC7


"A transient receptor potential cation channel TRPC3/6/7 that is a translation product of the human TRPC7 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:Q9HCX4

short transient receptor potential channel 7 (human)

hTRPC7


"A short transient receptor potential cation channel TRPC7 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9HCX4]

Yes

organism-sequence



PR:Q9HCX4-1

short transient receptor potential channel 7 isoform 1 (human)

hTRPC7/iso:1


"A short transient receptor potential cation channel TRPC7 isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9HCX4]


organism-sequence



PR:Q9HCX4-2

short transient receptor potential channel 7 isoform h2 (human)

hTRPC7/iso:h2


"A short transient receptor potential channel 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9HCX4-2." [PRO:DNx, UniProtKB:Q9HCX4]


organism-sequence



PR:Q9HCX4-3

short transient receptor potential channel 7 isoform h3 (human)

hTRPC7/iso:h3


"A short transient receptor potential channel 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9HCX4-3." [PRO:DNx, UniProtKB:Q9HCX4]


organism-gene



PR:Q9WVC5

short transient receptor potential channel 7 (mouse)

mTRPC7


"A short transient receptor potential cation channel TRPC7 that is encoded in the genome of mouse." [OMA:Q9WVC5, PRO:DNx]


organism-sequence



PR:Q9WVC5-1

short transient receptor potential channel 7 isoform 1 (mouse)

mTRPC7/iso:1


"A short transient receptor potential cation channel TRPC7 isoform 1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:Q9WVC5]

Yes

sequence



PR:000001081

short transient receptor potential cation channel TRPC7 isoform 1

TRPC7/iso:1


"A short transient receptor potential cation channel TRPC7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9WVC5-1 or a 1:1 ortholog thereof." [PMID:10488066]


organism-sequence



PR:Q9HCX4-1

short transient receptor potential channel 7 isoform 1 (human)

hTRPC7/iso:1


"A short transient receptor potential cation channel TRPC7 isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9HCX4]


organism-sequence



PR:Q9WVC5-1

short transient receptor potential channel 7 isoform 1 (mouse)

mTRPC7/iso:1


"A short transient receptor potential cation channel TRPC7 isoform 1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:Q9WVC5]

Yes

gene



PR:000016696

short transient receptor potential channel 6

TRPC6


"A transient receptor potential cation channel TRPC3/6/7 that is a translation product of the human TRPC6 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q61143

short transient receptor potential channel 6 (mouse)

mTRPC6


"A short transient receptor potential channel 6 that is encoded in the genome of mouse." [OMA:Q61143, PRO:DNx]


organism-gene



PR:Q9Y210

short transient receptor potential channel 6 (human)

hTRPC6


"A short transient receptor potential channel 6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9Y210]


organism-sequence



PR:Q9Y210-1

short transient receptor potential channel 6 isoform h1 (human)

hTRPC6/iso:h1


"A short transient receptor potential channel 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y210-1." [PRO:DNx, UniProtKB:Q9Y210]


organism-sequence



PR:Q9Y210-2

short transient receptor potential channel 6 isoform h2 (human)

hTRPC6/iso:h2


"A short transient receptor potential channel 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y210-2." [PRO:DNx, UniProtKB:Q9Y210]


organism-sequence



PR:Q9Y210-3

short transient receptor potential channel 6 isoform h3 (human)

hTRPC6/iso:h3


"A short transient receptor potential channel 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y210-3." [PRO:DNx, UniProtKB:Q9Y210]


organism-modification



PR:000058350

short transient receptor potential channel 6 N-glycosylated 1 (human)

hTRPC6/NGlyco:1


"A short transient receptor potential channel 6 (human) that has been N-glycosylated at the residue equivalent to Asn-473 of the amino acid sequence represented by UniProtKB:Q9Y210-1, in which the glycan composition is represented by GlyTouCan:G08293MJ. Example: UniProtKB:Q9Y210-1, Asn-473, MOD:00160~GNO:G08293MJ." [GlyGen:Q9Y210-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000058351

short transient receptor potential channel 6 N-glycosylated 2 (human)

hTRPC6/NGlyco:2


"A short transient receptor potential channel 6 (human) that has been N-glycosylated at the residue equivalent to Asn-473 of the amino acid sequence represented by UniProtKB:Q9Y210-1, in which the glycan composition is represented by GlyTouCan:G12580WI. Example: UniProtKB:Q9Y210-1, Asn-473, MOD:00160~GNO:G12580WI." [GlyGen:Q9Y210-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000072935

short transient receptor potential channel 6 phosphorylated 1 (human)

hTRPC6/Phos:1


"A short transient receptor potential channel 6 (human) that has been phosphorylated on the residue at the position equivalent to Thr-402 of the amino acid sequence represented by UniProtKB:Q9Y210-1. Example: UniProtKB:Q9Y210-1, Thr-402, MOD:00047." [IEDB_epitope:2148183, PRO:DNx]


family



PR:000001074

transient receptor potential cation channel TRPC with PDZ-binding motif

TRPV4/iso:E


"A transient receptor potential cation channel TRPC with a carboxyl-terminal PDZ-binding motif (VTTRL). They form homomeric or heteromeric (with TRPC1) cation channels that are activated following stimulation of Gq-coupled receptors." [PMID:16382100, PMID:16460286, PMID:17579562, PRO:WCB]


gene



PR:000001075

short transient receptor potential cation channel TRPC4

TRPC4


"A transient receptor potential cation channel TRPC with PDZ-binding motif that is a translation product of the human TRPC4 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:O35119

short transient receptor potential channel 4 (rat)

rTRPC4


"A short transient receptor potential cation channel TRPC4 that is encoded in the genome of rat." [OMA:O35119, PRO:DNx]


organism-sequence



PR:O35119-1

short transient receptor potential channel 4 isoform alpha (rat)

rTRPC4/iso:Alpha


"A short transient receptor potential cation channel TRPC4 isoform 1 that is encoded in the genome of rat." [PRO:CNA]


organism-sequence



PR:O35119-2

short transient receptor potential channel 4 isoform beta (rat)

rTRPC4/iso:Beta


"A short transient receptor potential cation channel TRPC4 isoform 2 that is encoded in the genome of rat." [PRO:CNA]


organism-gene



PR:Q9QUQ5

short transient receptor potential channel 4 (mouse)

mTRPC4


"A short transient receptor potential cation channel TRPC4 that is encoded in the genome of mouse." [OMA:Q9QUQ5, PRO:DNx]

Yes

organism-sequence



PR:Q9QUQ5-1

short transient receptor potential channel 4 isoform alpha (mouse)

mTRPC4/iso:Alpha


"A short transient receptor potential cation channel TRPC4 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-sequence



PR:Q9QUQ5-2

short transient receptor potential channel 4 isoform beta (mouse)

mTRPC4/iso:Beta


"A short transient receptor potential cation channel TRPC4 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]


organism-gene



PR:Q9UBN4

short transient receptor potential channel 4 (human)

hTRPC4


"A short transient receptor potential cation channel TRPC4 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9UBN4]


organism-sequence



PR:Q9UBN4-1

short transient receptor potential channel 4 isoform alpha (human)

hTRPC4/iso:Alpha


"A short transient receptor potential cation channel TRPC4 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-sequence



PR:Q9UBN4-2

short transient receptor potential channel 4 isoform beta (human)

hTRPC4/iso:Beta


"A short transient receptor potential cation channel TRPC4 isoform 2 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-sequence



PR:Q9UBN4-3

short transient receptor potential channel 4 isoform delta (human)

hTRPC4/iso:Delta


"A short transient receptor potential cation channel TRPC4 isoform 3 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q9UBN4-4

short transient receptor potential channel 4 isoform gamma (human)

hTRPC4/iso:Gamma


"A short transient receptor potential cation channel TRPC4 isoform 4 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q9UBN4-5

short transient receptor potential channel 4 isoform Epsilon (human)

hTRPC4/iso:Epsilon


"A short transient receptor potential channel 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBN4-5." [PRO:DNx, UniProtKB:Q9UBN4]


organism-sequence



PR:Q9UBN4-6

short transient receptor potential channel 4 isoform Zeta (human)

hTRPC4/iso:Zeta


"A short transient receptor potential channel 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBN4-6." [PRO:DNx, UniProtKB:Q9UBN4]


organism-sequence



PR:Q9UBN4-7

short transient receptor potential channel 4 isoform Eta (human)

hTRPC4/iso:Eta


"A short transient receptor potential channel 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBN4-7." [PRO:DNx, UniProtKB:Q9UBN4]


sequence



PR:000001076

short transient receptor potential cation channel TRPC4 isoform 1

TRPC4/iso:1


"A short transient receptor potential cation channel TRPC4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBN4-1 or a 1:1 ortholog thereof." [PMID:11163362, PRO:CNA]


organism-sequence



PR:O35119-1

short transient receptor potential channel 4 isoform alpha (rat)

rTRPC4/iso:Alpha


"A short transient receptor potential cation channel TRPC4 isoform 1 that is encoded in the genome of rat." [PRO:CNA]


organism-sequence



PR:Q9QUQ5-1

short transient receptor potential channel 4 isoform alpha (mouse)

mTRPC4/iso:Alpha


"A short transient receptor potential cation channel TRPC4 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-sequence



PR:Q9UBN4-1

short transient receptor potential channel 4 isoform alpha (human)

hTRPC4/iso:Alpha


"A short transient receptor potential cation channel TRPC4 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

sequence



PR:000001077

short transient receptor potential cation channel TRPC4 isoform 2

TRPC4/iso:2


"A short transient receptor potential cation channel TRPC4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBN4-2 or a 1:1 ortholog thereof. This form lacks a region of around 84 residues at the C-terminal domain, but conserves the PDZ-binding motif as compared to isoform 1." [PMID:11713258, PRO:CNA]


organism-sequence



PR:O35119-2

short transient receptor potential channel 4 isoform beta (rat)

rTRPC4/iso:Beta


"A short transient receptor potential cation channel TRPC4 isoform 2 that is encoded in the genome of rat." [PRO:CNA]


organism-sequence



PR:Q9QUQ5-2

short transient receptor potential channel 4 isoform beta (mouse)

mTRPC4/iso:Beta


"A short transient receptor potential cation channel TRPC4 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]


organism-sequence



PR:Q9UBN4-2

short transient receptor potential channel 4 isoform beta (human)

hTRPC4/iso:Beta


"A short transient receptor potential cation channel TRPC4 isoform 2 that is encoded in the genome of human." [PRO:CNA]

Yes

sequence



PR:000001078

short transient receptor potential cation channel TRPC4 isoform 3

TRPC4/iso:3


"A short transient receptor potential cation channel TRPC4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBN4-3 or a 1:1 ortholog thereof. This form lacks a region of around 140 residues at the C-terminal domain, but conserves the PDZ-binding motif as compared to isoform 1." [PMID:11163362, PRO:CNA]


organism-sequence



PR:Q9UBN4-3

short transient receptor potential channel 4 isoform delta (human)

hTRPC4/iso:Delta


"A short transient receptor potential cation channel TRPC4 isoform 3 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000001079

short transient receptor potential cation channel TRPC4 isoform 4

TRPC4/iso:4


"A short transient receptor potential cation channel TRPC4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBN4-4 or a 1:1 ortholog thereof." [PMID:11163362, PRO:CNA]


organism-sequence



PR:Q9UBN4-4

short transient receptor potential channel 4 isoform gamma (human)

hTRPC4/iso:Gamma


"A short transient receptor potential cation channel TRPC4 isoform 4 that is encoded in the genome of human." [PRO:CNA]


gene



PR:000001725

short transient receptor potential cation channel TRPC2

Trpc2


"A transient receptor potential cation channel TRPC that is a translation product of the mouse Trpc2 gene or a 1:1 ortholog thereof. It mediates both receptor- and store depletion-triggered calcium entry. It plays an important role in the transduction machinery underlying the detection of pheromone signals by the vomeronasal organ (VNO), a part of the accessory olfactory system." [PMID:15971083, PMID:17217050]


organism-gene



PR:Q9R244

short transient receptor potential channel 2 (mouse)

mTrpc2


"A short transient receptor potential cation channel TRPC2 that is encoded in the genome of mouse." []

Yes

organism-sequence



PR:Q9R244-1

short transient receptor potential channel 2 isoform 1 (mouse)

mTrpc2/iso:1


"A short transient receptor potential cation channel TRPC2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-sequence



PR:Q9R244-2

short transient receptor potential channel 2 isoform 2 (mouse)

mTrpc2/iso:2


"A short transient receptor potential cation channel TRPC2 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-sequence



PR:Q9R244-3

short transient receptor potential channel 2 isoform 3 (mouse)

mTrpc2/iso:3


"A short transient receptor potential cation channel TRPC2 isoform 3 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-sequence



PR:Q9R244-4

short transient receptor potential channel 2 isoform 4 (mouse)

mTrpc2/iso:4


"A short transient receptor potential cation channel TRPC2 isoform 4 that is encoded in the genome of mouse." [PRO:CNA]

Yes

sequence



PR:000001726

short transient receptor potential cation channel TRPC2 isoform 1

Trpc2/iso:1


"A short transient receptor potential cation channel TRPC2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9R244-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:Q9R244-1

short transient receptor potential channel 2 isoform 1 (mouse)

mTrpc2/iso:1


"A short transient receptor potential cation channel TRPC2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

sequence



PR:000001727

short transient receptor potential cation channel TRPC2 isoform 2

Trpc2/iso:2


"A short transient receptor potential cation channel TRPC2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9R244-2 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:Q9R244-2

short transient receptor potential channel 2 isoform 2 (mouse)

mTrpc2/iso:2


"A short transient receptor potential cation channel TRPC2 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]

Yes

sequence



PR:000001728

short transient receptor potential cation channel TRPC2 isoform 3

Trpc2/iso:3


"A short transient receptor potential cation channel TRPC2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9R244-3 or a 1:1 ortholog thereof." [PMID:10998353, PRO:CNA]


organism-sequence



PR:Q9R244-3

short transient receptor potential channel 2 isoform 3 (mouse)

mTrpc2/iso:3


"A short transient receptor potential cation channel TRPC2 isoform 3 that is encoded in the genome of mouse." [PRO:CNA]

Yes

sequence



PR:000001729

short transient receptor potential cation channel TRPC2 isoform 4

Trpc2/iso:4


"A short transient receptor potential cation channel TRPC2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9R244-4 or a 1:1 ortholog thereof." [PMID:10998353, PRO:CNA]


organism-sequence



PR:Q9R244-4

short transient receptor potential channel 2 isoform 4 (mouse)

mTrpc2/iso:4


"A short transient receptor potential cation channel TRPC2 isoform 4 that is encoded in the genome of mouse." [PRO:CNA]

Yes

gene



PR:000016693

short transient receptor potential channel 1

TRPC1


"A transient receptor potential cation channel TRPC that is a translation product of the human TRPC1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P48995

short transient receptor potential channel 1 (human)

hTRPC1


"A short transient receptor potential channel 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P48995]


organism-sequence



PR:P48995-1

short transient receptor potential channel 1 isoform Long (human)

hTRPC1/iso:Long


"A short transient receptor potential channel 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P48995-2

short transient receptor potential channel 1 isoform Short (human)

hTRPC1/iso:Short


"A short transient receptor potential channel 1 isoform 2 that is encoded in the genome of human." [PRO:DNx]


organism-gene



PR:Q61056

short transient receptor potential channel 1 (mouse)

mTRPC1


"A short transient receptor potential channel 1 that is encoded in the genome of mouse." [OMA:Q61056, PRO:DNx]


organism-sequence



PR:Q61056-1

short transient receptor potential channel 1 isoform Alpha (mouse)

mTRPC1/iso:Alpha


"A short transient receptor potential channel 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:Q61056-2

short transient receptor potential channel 1 isoform Beta (mouse)

mTRPC1/iso:Beta


"A short transient receptor potential channel 1 isoform 2 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:Q9QX01

short transient receptor potential channel 1 (rat)

rTRPC1


"A short transient receptor potential channel 1 that is encoded in the genome of rat." [OMA:Q9QX01, PRO:DNx]


organism-sequence



PR:Q9QX01-1

short transient receptor potential channel 1 isoform Beta (rat)

rTRPC1/iso:Beta


"A short transient receptor potential channel 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QX01-1." [PRO:DNx, UniProtKB:Q9QX01]


organism-sequence



PR:Q9QX01-2

short transient receptor potential channel 1 isoform Alpha (rat)

rTRPC1/iso:Alpha


"A short transient receptor potential channel 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QX01-2." [PRO:DNx, UniProtKB:Q9QX01]


sequence



PR:000039570

short transient receptor potential channel 1 isoform 1

TRPC1/iso:1


"A short transient receptor potential channel 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48995-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P48995-1

short transient receptor potential channel 1 isoform Long (human)

hTRPC1/iso:Long


"A short transient receptor potential channel 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q61056-1

short transient receptor potential channel 1 isoform Alpha (mouse)

mTRPC1/iso:Alpha


"A short transient receptor potential channel 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000039571

short transient receptor potential channel 1 isoform 2

TRPC1/iso:2


"A short transient receptor potential channel 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48995-2 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P48995-2

short transient receptor potential channel 1 isoform Short (human)

hTRPC1/iso:Short


"A short transient receptor potential channel 1 isoform 2 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q61056-2

short transient receptor potential channel 1 isoform Beta (mouse)

mTRPC1/iso:Beta


"A short transient receptor potential channel 1 isoform 2 that is encoded in the genome of mouse." [PRO:DNx]


gene



PR:000016695

short transient receptor potential channel 5

TRPC5


"A transient receptor potential cation channel TRPC that is a translation product of the human TRPC5 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q9QX29

short transient receptor potential channel 5 (mouse)

mTRPC5


"A short transient receptor potential channel 5 that is encoded in the genome of mouse." [OMA:Q9QX29, PRO:DNx]


organism-gene



PR:Q9UL62

short transient receptor potential channel 5 (human)

hTRPC5


"A short transient receptor potential channel 5 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UL62]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q13507-1 hTRPC3/iso:1 acts_upstream_of_or_withinGO:0007602 phototransduction PMID:9215637
enablesGO:0005515 protein binding PMID:15744307
GO:0015279 store-operated calcium channel activity PMID:9215637
located_inGO:0005886 plasma membrane PMID:9368034
PR:Q9HCX4 hTRPC7 enablesGO:0005515 protein binding with PR:P20591 hMX1 PMID:15757897
PR:Q9QUQ5 mTRPC4 acts_upstream_of_or_withinGO:0014051 gamma-aminobutyric acid secretion PMID:14668438
located_inGO:0005901 caveola PMID:11897792
PR:Q9QUQ5-1 mTRPC4/iso:Alpha enablesGO:0015279 store-operated calcium channel activity MGI_ref:3525810; PMID:15044151
located_inGO:0005886 plasma membrane MGI_ref:3525810; PMID:15044151
PR:Q9R244 mTrpc2 acts_upstream_of_or_withinNOT GO:0015279 store-operated calcium channel activity PMID:10998353
PR:Q9R244-1 mTrpc2/iso:1 enablesGO:0005516 calmodulin binding MGI_ref:2652910; PMID:12601176
PR:Q9R244-2 mTrpc2/iso:2 enablesGO:0005516 calmodulin binding PMID:12601176
PR:Q9R244-3 mTrpc2/iso:3 located_inGO:0000139 Golgi membrane MGI_ref:1913270; PMID:10998353
GO:0005635 nuclear envelope MGI_ref:1913270; PMID:10998353
GO:0005789 endoplasmic reticulum membrane MGI_ref:1913270; PMID:10998353
PR:Q9R244-4 mTrpc2/iso:4 located_inGO:0000139 Golgi membrane PMID:10998353
GO:0005635 nuclear envelope MGI_ref:1913270; PMID:10998353
GO:0005789 endoplasmic reticulum membrane MGI_ref:1913270; PMID:10998353
PR:Q9UBN4-1 hTRPC4/iso:Alpha enablescontributes_to GO:0015279 store-operated calcium channel activity PMID:11713258
GO:0042802 identical protein binding PMID:11713258
located_inGO:0005886 plasma membrane PMID:11713258
PR:Q9UBN4-2 hTRPC4/iso:Beta enablescontributes_to GO:0015279 store-operated calcium channel activity PMID:11713258
GO:0042802 identical protein binding PMID:11713258
located_inGO:0005886 plasma membrane PMID:11713258
PR:Q9WVC5-1 mTRPC7/iso:1 acts_upstream_of_or_withinGO:0006816 calcium ion transport PMID:10488066
enablescontributes_to GO:0005262 calcium channel activity PMID:10488066
contributes_to GO:0006828 manganese ion transport PMID:10488066
located_inGO:0016020 membrane PMID:10488066