back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - transient receptor potential cation channel TRPV
PR:000000681 - http://purl.obolibrary.org/obo/PR_000000681
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000681   
  PRO nametransient receptor potential cation channel TRPV 
  Synonyms
PRO-Short-label: EXACT:fam:TRPV
  Definition"A transient receptor potential channel protein that is a member of the subfamily V of the transient receptor potential cation channels (TRPs), with amino- and carboxyl-terminal intracellular domains separated by a domain (common with other ion channels) containing six transmembrane helices (S1-S6) in which the last two helices (S5 and S6) flank a loop, called the pore loop, which determines ion selectivity. The amino-terminal domain contains up to 6 copies of detectable ankyrin repeat (Pfam:PF00023). Most TRPs are relatively non-selective. They may be modulated by voltage changes but channel gating is generally effected by other means." [PMID:16382100, PMID:16460286, PMID:17579562, PRO:WCB] 
  PRO Categoryfamily 
  ParentPR:000044657 transient receptor potential channel protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family2                                                  Organism-Family 0                                        
         Gene6                                                  Organism-Gene 20                                        
         Sequence11                                                  Organism-Sequence 26                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
PIRSF:PIRSF038527
Back to top
Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000000681 transient receptor potential cation channel TRPV
fam:TRPV

gene


PR:000001060 transient receptor potential cation channel TRPV3
TRPV3

organism-gene


PR:Q8K424 transient receptor potential cation channel subfamily V member 3 (mouse)
mTRPV3

organism-sequence


PR:Q8K424-1 transient receptor potential cation channel subfamily V member 3 isoform A (mouse)
mTRPV3/iso:A
Yes
organism-gene


PR:Q8NET8 transient receptor potential cation channel subfamily V member 3 (human)
hTRPV3

organism-sequence


PR:Q8NET8-1 transient receptor potential cation channel subfamily V member 3 isoform 1 (human)
hTRPV3/iso:1
Yes
organism-sequence


PR:Q8NET8-2 transient receptor potential cation channel subfamily V member 3 isoform A (human)
hTRPV3/iso:A

organism-sequence


PR:Q8NET8-3 transient receptor potential cation channel subfamily V member 3 isoform B (human)
hTRPV3/iso:B

sequence


PR:000001061 transient receptor potential cation channel TRPV3 isoform A
TRPV3/iso:A

organism-sequence


PR:Q8K424-1 transient receptor potential cation channel subfamily V member 3 isoform A (mouse)
mTRPV3/iso:A
Yes
organism-sequence


PR:Q8NET8-2 transient receptor potential cation channel subfamily V member 3 isoform A (human)
hTRPV3/iso:A

sequence


PR:000001062 transient receptor potential cation channel TRPV3 isoform 1
TRPV3/iso:1

organism-sequence


PR:Q8NET8-1 transient receptor potential cation channel subfamily V member 3 isoform 1 (human)
hTRPV3/iso:1
Yes
sequence


PR:000001063 transient receptor potential cation channel TRPV3 isoform B
TRPV3/iso:B

organism-sequence


PR:Q8NET8-3 transient receptor potential cation channel subfamily V member 3 isoform B (human)
hTRPV3/iso:B

gene


PR:000001064 transient receptor potential cation channel TRPV2
TRPV2

organism-gene


PR:Q9WTR1 transient receptor potential cation channel subfamily V member 2 (mouse)
mTRPV2

organism-sequence


PR:Q9WTR1-1 transient receptor potential cation channel subfamily V member 2 isoform 1 (mouse)
mTRPV2/iso:1

organism-gene


PR:Q9WUD2 transient receptor potential cation channel subfamily V member 2 (rat)
rTRPV2

organism-gene


PR:Q9Y5S1 transient receptor potential cation channel subfamily V member 2 (human)
hTRPV2

organism-modification


PR:000066296 transient receptor potential cation channel subfamily V member 2 cysteinylated 1 (human)
hTRPV2/Cyst:1

organism-modification


PR:000077578 transient receptor potential cation channel subfamily V member 2 deaminated 1 (human)
hTRPV2/Deam:1

organism-modification


PR:000082198 transient receptor potential cation channel subfamily V member 2 deaminated 2 (human)
hTRPV2/Deam:2

organism-modification


PR:000084990 transient receptor potential cation channel subfamily V member 2 deaminated 3 (human)
hTRPV2/Deam:3

sequence


PR:000001066 transient receptor potential cation channel TRPV2 isoform 1
TRPV2/iso:1

organism-sequence


PR:Q9WTR1-1 transient receptor potential cation channel subfamily V member 2 isoform 1 (mouse)
mTRPV2/iso:1

gene


PR:000001065 transient receptor potential cation channel TRPV1
TRPV1

organism-gene


PR:O35433 transient receptor potential cation channel subfamily V member 1 (rat)
rTRPV1

organism-sequence


PR:O35433-1 transient receptor potential cation channel subfamily V member 1 isoform r1 (rat)
rTRPV1/iso:r1

organism-sequence


PR:O35433-2 transient receptor potential cation channel subfamily V member 1 isoform r2 (rat)
rTRPV1/iso:r2

organism-sequence


PR:O35433-3 transient receptor potential cation channel subfamily V member 1 isoform r3 (rat)
rTRPV1/iso:r3

organism-gene


PR:Q697L1 transient receptor potential cation channel subfamily V member 1 (dog)
dog-TRPV1

organism-gene


PR:Q6R5A3 transient receptor potential cation channel subfamily V member 1 (guinea pig)
gPig-TRPV1

organism-gene


PR:Q704Y3 transient receptor potential cation channel subfamily V member 1 (mouse)
mTRPV1

organism-sequence


PR:Q704Y3-1 transient receptor potential cation channel subfamily V member 1 isoform 1 (mouse)
mTRPV1/iso:1
Yes
organism-sequence


PR:Q704Y3-2 transient receptor potential cation channel subfamily V member 1 isoform m2 (mouse)
mTRPV1/iso:m2

organism-gene


PR:Q8NER1 transient receptor potential cation channel subfamily V member 1 (human)
hTRPV1

organism-sequence


PR:Q8NER1-1 transient receptor potential cation channel subfamily V member 1 isoform 1 (human)
hTRPV1/iso:1

organism-sequence


PR:Q8NER1-3 transient receptor potential cation channel subfamily V member 1 isoform h2 (human)
hTRPV1/iso:h2

organism-modification


PR:000045997 transient receptor potential cation channel subfamily V member 1 phosphorylated 1 (human)
hTRPV1/Phos:1

sequence


PR:000001067 transient receptor potential cation channel TRPV1 isoform 1
TRPV1/iso:1

organism-sequence


PR:Q704Y3-1 transient receptor potential cation channel subfamily V member 1 isoform 1 (mouse)
mTRPV1/iso:1
Yes
organism-sequence


PR:Q8NER1-1 transient receptor potential cation channel subfamily V member 1 isoform 1 (human)
hTRPV1/iso:1

gene


PR:000001068 transient receptor potential cation channel TRPV4
TRPV4

organism-gene


PR:A0A1D5PXA5 transient receptor potential cation channel subfamily V member 4 (chicken)
chick-TRPV4

organism-gene


PR:Q9EPK8 transient receptor potential cation channel subfamily V member 4 (mouse)
mTRPV4
Yes
organism-sequence


PR:Q9EPK8-1 transient receptor potential cation channel subfamily V member 4 isoform A (mouse)
mTRPV4/iso:A
Yes
organism-modification


PR:000046053 transient receptor potential cation channel subfamily V member 4 phosphorylated 1 (mouse)
mTRPV4/Phos:1

organism-gene


PR:Q9ERZ8 transient receptor potential cation channel subfamily V member 4 (rat)
rTRPV4

organism-gene


PR:Q9HBA0 transient receptor potential cation channel subfamily V member 4 (human)
hTRPV4

organism-sequence


PR:Q9HBA0-1 transient receptor potential cation channel subfamily V member 4 isoform A (human)
hTRPV4/iso:A
Yes
organism-sequence


PR:Q9HBA0-2 transient receptor potential cation channel subfamily V member 4 isoform B (human)
hTRPV4/iso:B
Yes
organism-sequence


PR:Q9HBA0-3 transient receptor potential cation channel subfamily V member 4 isoform h3 (human)
hTRPV4/iso:h3

organism-sequence


PR:Q9HBA0-4 transient receptor potential cation channel subfamily V member 4 isoform C (human)
hTRPV4/iso:C
Yes
organism-sequence


PR:Q9HBA0-5 transient receptor potential cation channel subfamily V member 4 isoform D (human)
hTRPV4/iso:D
Yes
organism-sequence


PR:Q9HBA0-6 transient receptor potential cation channel subfamily V member 4 isoform E (human)
hTRPV4/iso:E
Yes
sequence


PR:000001069 transient receptor potential cation channel TRPV4 isoform A
TRPV4/iso:A

organism-sequence


PR:Q9EPK8-1 transient receptor potential cation channel subfamily V member 4 isoform A (mouse)
mTRPV4/iso:A
Yes
organism-sequence


PR:Q9HBA0-1 transient receptor potential cation channel subfamily V member 4 isoform A (human)
hTRPV4/iso:A
Yes
sequence


PR:000001070 transient receptor potential cation channel TRPV4 isoform B
TRPV4/iso:B

organism-sequence


PR:Q9HBA0-2 transient receptor potential cation channel subfamily V member 4 isoform B (human)
hTRPV4/iso:B
Yes
sequence


PR:000001071 transient receptor potential cation channel TRPV4 isoform C
TRPV4/iso:C

organism-sequence


PR:Q9HBA0-4 transient receptor potential cation channel subfamily V member 4 isoform C (human)
hTRPV4/iso:C
Yes
sequence


PR:000001072 transient receptor potential cation channel TRPV4 isoform D
TRPV4/iso:D

organism-sequence


PR:Q9HBA0-5 transient receptor potential cation channel subfamily V member 4 isoform D (human)
hTRPV4/iso:D
Yes
sequence


PR:000001073 transient receptor potential cation channel TRPV4 isoform E
TRPV4/iso:E

organism-sequence


PR:Q9HBA0-6 transient receptor potential cation channel subfamily V member 4 isoform E (human)
hTRPV4/iso:E
Yes
family


PR:000000687 calcium-selective transient receptor potential cation channel TRPV
CNGA1

gene


PR:000000776 transient receptor potential cation channel subfamily V member 5
TRPV5

organism-gene


PR:P69744 transient receptor potential cation channel subfamily V member 5 (mouse)
mTRPV5
Yes
organism-sequence


PR:P69744-1 transient receptor potential cation channel subfamily V member 5 isoform 1 (mouse)
mTRPV5/iso:1

organism-gene


PR:Q9JIP0 transient receptor potential cation channel subfamily V member 5 (rat)
rTRPV5

organism-sequence


PR:Q9JIP0-1 transient receptor potential cation channel subfamily V member 5 isoform 1 (rat)
rTRPV5/iso:1

organism-sequence


PR:Q9JIP0-2 transient receptor potential cation channel subfamily V member 5 isoform r2 (rat)
rTRPV5/iso:r2

organism-gene


PR:Q9NQA5 transient receptor potential cation channel subfamily V member 5 (human)
hTRPV5

organism-sequence


PR:Q9NQA5-1 transient receptor potential cation channel subfamily V member 5 isoform h1 (human)
hTRPV5/iso:h1

organism-sequence


PR:Q9NQA5-2 transient receptor potential cation channel subfamily V member 5 isoform h2 (human)
hTRPV5/iso:h2

sequence


PR:000040114 transient receptor potential cation channel subfamily V member 5 isoform 1
TRPV5/iso:1

organism-sequence


PR:P69744-1 transient receptor potential cation channel subfamily V member 5 isoform 1 (mouse)
mTRPV5/iso:1

organism-sequence


PR:Q9JIP0-1 transient receptor potential cation channel subfamily V member 5 isoform 1 (rat)
rTRPV5/iso:1

gene


PR:000000777 transient receptor potential cation channel subfamily V member 6
TRPV6

organism-gene


PR:Q91WD2 transient receptor potential cation channel subfamily V member 6 (mouse)
mTRPV6
Yes
organism-gene


PR:Q9H1D0 transient receptor potential cation channel subfamily V member 6 (human)
hTRPV6

organism-sequence


PR:Q9H1D0-1 transient receptor potential cation channel subfamily V member 6 isoform h1 (human)
hTRPV6/iso:h1

organism-sequence


PR:Q9H1D0-2 transient receptor potential cation channel subfamily V member 6 isoform h2 (human)
hTRPV6/iso:h2

organism-gene


PR:Q9R186 transient receptor potential cation channel subfamily V member 6 (rat)
rTRPV6

Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P69744 mTRPV5 acts_upstream_of_or_withinGO:0006816 calcium ion transport PMID:15665527
GO:0051262 protein tetramerization PMID:12574114
enablesGO:0005262 calcium channel activity PMID:15665527
GO:0005515 protein binding PMID:15355307
located_inGO:0016324 apical plasma membrane PMID:12205031
PR:Q704Y3-1 mTRPV1/iso:1 enablesGO:0005216 monoatomic ion channel activity MGI_ref:3053490; PMID:15194687
PR:Q8K424-1 mTRPV3/iso:A acts_upstream_of_or_withinGO:0009266 response to temperature stimulus PMID:12016205
enablescontributes_to GO:0005261 monoatomic cation channel activity PMID:12016205
PR:Q8NET8-1 hTRPV3/iso:1 acts_upstream_of_or_withinGO:0009266 response to temperature stimulus PMID:12077604; PMID:12077606
enablescontributes_to GO:0005261 monoatomic cation channel activity PMID:12077604; PMID:12077606
PR:Q91WD2 mTRPV6 acts_upstream_of_or_withinGO:0006816 calcium ion transport PMID:12077127
enablesGO:0005262 calcium channel activity PMID:12077127
PR:Q9EPK8 mTRPV4 acts_upstream_of_or_withinGO:0030103 vasopressin secretion PMID:12777254
GO:0042538 hyperosmotic salinity response PMID:12777254
GO:0047484 regulation of response to osmotic stress PMID:12777254
enablesGO:0005034 osmosensor activity PMID:11025659
PR:Q9EPK8-1 mTRPV4/iso:A acts_upstream_of_or_withinGO:0006970 response to osmotic stress PMID:11025659
GO:0007231 osmosensory signaling pathway PMID:11025659
enablescontributes_to GO:0005262 calcium channel activity PMID:11025659
GO:0005515 protein binding PMID:14517216
located_inGO:0005886 plasma membrane PMID:14517216
PR:Q9HBA0-1 hTRPV4/iso:A enablesGO:0042802 identical protein binding with PR:Q9HBA0-1 PMID:16293632
located_inGO:0005886 plasma membrane PMID:16293632
PR:Q9HBA0-2 hTRPV4/iso:B located_inGO:0005783 endoplasmic reticulum PMID:16293632
PR:Q9HBA0-4 hTRPV4/iso:C located_inGO:0005783 endoplasmic reticulum PMID:16293632
PR:Q9HBA0-5 hTRPV4/iso:D enablesGO:0042802 identical protein binding with PR:Q9HBA0-5 PMID:16293632
located_inGO:0005886 plasma membrane PMID:16293632
PR:Q9HBA0-6 hTRPV4/iso:E located_inGO:0005783 endoplasmic reticulum PMID:16293632