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Protein Ontology report - voltage-gated potassium channel alpha subunit
PR:000000685 - http://purl.obolibrary.org/obo/PR_000000685
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000000685   
  PRO namevoltage-gated potassium channel alpha subunit 
  Synonyms
PRO-Short-label: EXACT:fam:Kchan_sub-a
  Definition"A voltage-gated potassium channel protein that has a core domain composition consisting of six transmembrane domains (S1-S6), arranged in a voltage sensor (S1-S4) and pore modules (S5-P-S6), and with both N and C termini on the intracellular side of the membrane. The charged S4 segment with a basic amino acid at every third position confers their voltage sensitivity. A hallmark of this class is the presence of an N-terminal K+ channel tetramerisation domain (Pfam:PF02214) (T1), which encodes molecular determinants for subfamily-specific assembly of alpha-subunits into functional tetrameric channels. Carbonyl oxygen atoms from the potassium channel signature sequence (TTxGYGD) line the selectivity filter, where they preferentially coordinate potassium. Voltage-gated potassium channels are composed of tetramers of alpha subunits with each alpha subunit containing a voltage sensor and contributing to the central pore. This pore is formed by these subunits that encircle a central ion conduction pathway." [PMID:16382097, PMID:17606609, PMID:9886290
  PRO Categoryfamily 
  ParentPR:000044654 voltage-gated potassium channel protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family6                                                  Organism-Family 0                                        
         Gene25                                                  Organism-Gene 74                                        
         Sequence32                                                  Organism-Sequence 90                                        
         Modification19                                                  Organism-Modification 22                                        
  Term Hierarchy
  Visualization
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Related Cross References

  Db identifiers
PIRSF:PIRSF002449
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000000685

voltage-gated potassium channel alpha subunit

fam:Kchan_sub-a


"A voltage-gated potassium channel protein that has a core domain composition consisting of six transmembrane domains (S1-S6), arranged in a voltage sensor (S1-S4) and pore modules (S5-P-S6), and with both N and C termini on the intracellular side of the membrane. The charged S4 segment with a basic amino acid at every third position confers their voltage sensitivity. A hallmark of this class is the presence of an N-terminal K+ channel tetramerisation domain (Pfam:PF02214) (T1), which encodes molecular determinants for subfamily-specific assembly of alpha-subunits into functional tetrameric channels. Carbonyl oxygen atoms from the potassium channel signature sequence (TTxGYGD) line the selectivity filter, where they preferentially coordinate potassium. Voltage-gated potassium channels are composed of tetramers of alpha subunits with each alpha subunit containing a voltage sensor and contributing to the central pore. This pore is formed by these subunits that encircle a central ion conduction pathway." [PMID:16382097, PMID:17606609, PMID:9886290]

Yes

gene



PR:000000683

voltage-gated potassium channel alpha subunit KCNA4

KCNA4


"A voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA4 gene or a 1:1 ortholog thereof. The Kv1.4 channel is a fast-inactivating channel involved in neuronal after hypolarization. It can coassemble with other Kv1 subunits. It is closely related to members of the shaker-related voltage-gated potassium channel, but has a unique N-terminal domain, with two tandem inactivation domains (ID1-ID2). ID1 may work as a pore-occluding ball domain, whereas ID2 most likely acts as a docking domain that attaches ID1 to the cytoplasmic face of the channel." [PMID:12590144]


organism-gene



PR:P15385

potassium voltage-gated channel subfamily A member 4 (rat)

rKCNA4


"A voltage-gated potassium channel alpha subunit KCNA4 that is encoded in the genome of rat." [OMA:P15385, PRO:DNx]


organism-gene



PR:P22459

potassium voltage-gated channel subfamily A member 4 (human)

hKCNA4


"A voltage-gated potassium channel alpha subunit KCNA4 that is encoded in the genome of human." []


organism-gene



PR:Q61423

potassium voltage-gated channel subfamily A member 4 (mouse)

mKCNA4


"A voltage-gated potassium channel alpha subunit KCNA4 that is encoded in the genome of mouse." [OMA:Q61423, PRO:DNx]


organism-sequence



PR:Q61423-1

potassium voltage-gated channel subfamily A member 4 isoform 1 (mouse)

mKCNA4/iso:1


"A voltage-gated potassium channel alpha subunit KCNA4 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-modification



PR:000044513

voltage-gated potassium channel alpha subunit KCNA4 isoform 1 phosphorylated 1 (mouse)

mKCNA4/iso:1/Phos:1


"A voltage-gated potassium channel alpha subunit KCNA4 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q61423-1, Ser-122, MOD:00046." [PRO:DNx]

Yes

sequence



PR:000000727

voltage-gated potassium channel alpha subunit KCNA4 isoform 1

KCNA4/iso:1


"A voltage-gated potassium channel alpha subunit KCNA4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61423-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:Q61423-1

potassium voltage-gated channel subfamily A member 4 isoform 1 (mouse)

mKCNA4/iso:1


"A voltage-gated potassium channel alpha subunit KCNA4 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-modification



PR:000044513

voltage-gated potassium channel alpha subunit KCNA4 isoform 1 phosphorylated 1 (mouse)

mKCNA4/iso:1/Phos:1


"A voltage-gated potassium channel alpha subunit KCNA4 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q61423-1, Ser-122, MOD:00046." [PRO:DNx]

Yes

modification



PR:000000778

voltage-gated potassium channel alpha subunit KCNA4 isoform 1 phosphorylated form

KCNA4/iso:1/PhosRes+


"A voltage-gated potassium channel alpha subunit KCNA4 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000000938

voltage-gated potassium channel alpha subunit KCNA4 isoform 1 phosphorylated 1

KCNA4/iso:1/Phos:1


"A voltage-gated potassium channel alpha subunit KCNA4 isoform 1 phosphorylated form in which the phosphorylation occurs at the Ser residue located at the N-terminal Glu rich sequence ELSEEEEDEEEEEEEEEEGR. Example: UniProtKB:Q61423-1, Ser-122, MOD:00046." [PMID:18056256]


organism-modification



PR:000044513

voltage-gated potassium channel alpha subunit KCNA4 isoform 1 phosphorylated 1 (mouse)

mKCNA4/iso:1/Phos:1


"A voltage-gated potassium channel alpha subunit KCNA4 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q61423-1, Ser-122, MOD:00046." [PRO:DNx]

Yes

gene



PR:000000724

voltage-gated potassium channel KCNF1

KCNF1


"A voltage-gated potassium channel alpha subunit that is a translation product of the human KCNF1 gene or a 1:1 ortholog thereof. KCNF1 is a modulator of the shab-related potassium channels (Kv2). Unlike other potassium channel subunits, KCNF1 subunits are not able to form functional channels on their own." [PMID:9696692]

Yes

organism-gene



PR:D4ADX7

voltage-gated potassium channel regulatory subunit KCNF1 (rat)

rKCNF1


"A voltage-gated potassium channel KCNF1 that is encoded in the genome of rat." [OMA:D4ADX7, PRO:DNx]


organism-gene



PR:Q7TSH7

voltage-gated potassium channel regulatory subunit KCNF1 (mouse)

mKCNF1


"A voltage-gated potassium channel KCNF1 that is encoded in the genome of mouse." [OMA:Q7TSH7, PRO:DNx]


organism-gene



PR:Q9H3M0

voltage-gated potassium channel regulatory subunit KCNF1 (human)

hKCNF1


"A voltage-gated potassium channel KCNF1 that is encoded in the genome of human." []


gene



PR:000000725

voltage-gated potassium channel KCNV1

KCNV1


"A voltage-gated potassium channel alpha subunit that is a translation product of the human KCNV1 gene or a 1:1 ortholog thereof. It has an atypical S6 segment containing the structural elements that modify inactivation of Kv2 channels. Similarly to KCNF1, KCNV1 and KCNS, KCNV2 subunits are not able to form functional channels on their own. Also in common with these modulatory subunits, it lacks the conserved PxP motif located in the distal part of S6. In this class the motif is PIA. The alteration of the PxP motif seems to be an important determinant of the regulatory function of modulatory subunits. It modulates the activity of KCNB1 and KCNB2 channels by changing kinetics and levels of expression and by shifting the half-inactivation potential to more polarized values." [PMID:16382104]

Yes

organism-gene



PR:P97557

potassium voltage-gated channel subfamily V member 1 (rat)

rKCNV1


"A voltage-gated potassium channel KCNV1 that is encoded in the genome of rat." [OMA:P97557, PRO:DNx]


organism-gene



PR:Q6PIU1

potassium voltage-gated channel subfamily V member 1 (human)

hKCNV1


"A voltage-gated potassium channel KCNV1 that is encoded in the genome of human." []


organism-sequence



PR:Q6PIU1-1

potassium voltage-gated channel subfamily V member 1 isoform 1 (human)

hKCNV1/iso:1


"A voltage-gated potassium channel KCNV1 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-gene



PR:Q8BZN2

potassium voltage-gated channel subfamily V member 1 (mouse)

mKCNV1


"A voltage-gated potassium channel KCNV1 that is encoded in the genome of mouse." [OMA:Q8BZN2, PRO:DNx]


organism-gene



PR:Q9XXD1

probable voltage-gated potassium channel subunit kvs-4 (worm)

KCNV1 (worm)


"A voltage-gated potassium channel KCNV1 that is encoded in the genome of worm." [OMA:Q9XXD1, PRO:DNx]


organism-sequence



PR:Q9XXD1-1

probable voltage-gated potassium channel subunit kvs-4 isoform a (worm)

KCNV1/iso:a (worm)


"A probable voltage-gated potassium channel subunit kvs-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9XXD1-1." [PRO:DNx, UniProtKB:Q9XXD1]


organism-sequence



PR:Q9XXD1-2

probable voltage-gated potassium channel subunit kvs-4 isoform b (worm)

KCNV1/iso:b (worm)


"A probable voltage-gated potassium channel subunit kvs-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9XXD1-2." [PRO:DNx, UniProtKB:Q9XXD1]


sequence



PR:000000801

voltage-gated potassium channel KCNV1 isoform 1

KCNV1/iso:1


"A voltage-gated potassium channel KCNV1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6PIU1-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:Q6PIU1-1

potassium voltage-gated channel subfamily V member 1 isoform 1 (human)

hKCNV1/iso:1


"A voltage-gated potassium channel KCNV1 isoform 1 that is encoded in the genome of human." [PRO:CNA]


gene



PR:000000726

voltage-gated potassium channel KCNV2

KCNV2


"A voltage-gated potassium channel alpha subunit that is a translation product of the human KCNV2 gene or a 1:1 ortholog thereof. Similarly to KCNF1, KCNV1 and KCNS, KCNV2 subunits are not able to form functional channels on their own. Also in common with these modulatory subunits, it lacks the conserved PxP motif located in the distal part of S6. In this class the motif is PIS. The alteration of the PxP motif seems to be an important determinant of the regulatory function of modulatory subunits." [PRO:CNA]

Yes

organism-gene



PR:Q8CFS6

potassium voltage-gated channel subfamily V member 2 (mouse)

mKCNV2


"A voltage-gated potassium channel KCNV2 that is encoded in the genome of mouse." [OMA:Q8CFS6, PRO:DNx]


organism-gene



PR:Q8TDN2

potassium voltage-gated channel subfamily V member 2 (human)

hKCNV2


"A voltage-gated potassium channel KCNV2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q8TDN2]


organism-sequence



PR:000000803

voltage-gated potassium channel KCNV2 sequence variant G459D (human)

hKCNV2/var:G459D


"A potassium voltage-gated channel subfamily V member 2 (human) that has an Asp residue at the position equivalent to Gly-459 of the amino acid sequence represented by UniProtKB:Q8TDN2. UniProtKB:Q8TDN2, Gly-459, CHEBI:29958." [PMID:16909397, PRO:CNA, PRO:DAN]

Yes

organism-sequence



PR:000000804

voltage-gated potassium channel KCNV2 sequence variant A259V (human)

hKCNV2/var:A259V


"A potassium voltage-gated channel subfamily V member 2 (human) that has a Val residue at the position equivalent to Ala-259 of the amino acid sequence represented by UniProtKB:Q8TDN2. UniProtKB:Q8TDN2, Ala-259, CHEBI:30015." [PMID:16909397, PRO:CNA, PRO:DAN]

Yes

organism-sequence



PR:000000805

voltage-gated potassium channel KCNV2 sequence variant L126Q (human)

hKCNV2/var:L126Q


"A potassium voltage-gated channel subfamily V member 2 (human) that has a Gln residue at the position equivalent to Leu-126 of the amino acid sequence represented by UniProtKB:Q8TDN2. UniProtKB:Q8TDN2, Leu-126, CHEBI:30011." [PMID:16909397, PRO:CNA, PRO:DAN]

Yes

organism-sequence



PR:000000806

voltage-gated potassium channel KCNV2 sequence variant 4 (human)

hKCNV2/var:4


"A potassium voltage-gated channel subfamily V member 2 (human) that has a three-residue deletion at the positions equivalent to 339-341 of the amino acid sequence represented by UniProtKB:Q8TDN2. These residues are part of segment S3. UniProtKB:Q8TDN2, 1-338, 342-545." [PMID:16909397, PRO:CNA, PRO:DAN]

Yes

organism-sequence



PR:000000807

voltage-gated potassium channel KCNV2 sequence variant S256W (human)

hKCNV2/var:S256W


"A potassium voltage-gated channel subfamily V member 2 (human) that has a Trp residue at the position equivalent to Ser-256 of the amino acid sequence represented by UniProtKB:Q8TDN2. UniProtKB:Q8TDN2, Ser-256, CHEBI:29954." [PMID:16909397, PRO:CNA, PRO:DAN]

Yes

organism-sequence



PR:000000808

voltage-gated potassium channel KCNV2 sequence variant W188C (human)

hKCNV2/var:W188C


"A potassium voltage-gated channel subfamily V member 2 (human) that has a Cys residue at the position equivalent to Trp-188 of the amino acid sequence represented by UniProtKB:Q8TDN2. UniProtKB:Q8TDN2, Trp-188, CHEBI:29950." [PMID:16909397, PRO:CNA, PRO:DAN]

Yes

organism-sequence



PR:Q8TDN2-1

potassium voltage-gated channel subfamily V member 2 isoform 1 (human)

hKCNV2/iso:1


"A voltage-gated potassium channel KCNV2 isoform 1 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000000802

voltage-gated potassium channel KCNV2 isoform 1

KCNV2/iso:1


"A voltage-gated potassium channel KCNV2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TDN2-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:Q8TDN2-1

potassium voltage-gated channel subfamily V member 2 isoform 1 (human)

hKCNV2/iso:1


"A voltage-gated potassium channel KCNV2 isoform 1 that is encoded in the genome of human." [PRO:CNA]


gene



PR:000009250

voltage-gated potassium channel subunit KCNA1

KCNA1


"A voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P10499

potassium voltage-gated channel subfamily A member 1 (rat)

rKCNA1


"A voltage-gated potassium channel subunit KCNA1 that is encoded in the genome of rat." [OMA:P10499, PRO:DNx]


organism-sequence



PR:P10499-1

potassium voltage-gated channel subfamily A member 1 isoform 1 (rat)

rKCNA1/iso:1


"A voltage-gated potassium channel subunit KCNA1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:P16388

potassium voltage-gated channel subfamily A member 1 (mouse)

mKCNA1


"A voltage-gated potassium channel subunit KCNA1 that is encoded in the genome of mouse." [OMA:P16388, PRO:DNx]


organism-sequence



PR:P16388-1

potassium voltage-gated channel subfamily A member 1 isoform 1 (mouse)

mKCNA1/iso:1


"A voltage-gated potassium channel subunit KCNA1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:Q09470

potassium voltage-gated channel subfamily A member 1 (human)

hKCNA1


"A voltage-gated potassium channel subunit KCNA1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q09470]


organism-sequence



PR:Q09470-1

potassium voltage-gated channel subfamily A member 1 isoform 1 (human)

hKCNA1/iso:1


"A voltage-gated potassium channel subunit KCNA1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000045890

potassium voltage-gated channel subfamily A member 1 phosphorylated 1 (human)

hKCNA1/Phos:1


"A potassium voltage-gated channel subfamily A member 1 (human) that has been phosphorylated at Ser-446. UniProtKB:Q09470, Ser-446, MOD:00046." [iPTMnet:Q09470, PMID:23774215]


sequence



PR:000040341

voltage-gated potassium channel subunit KCNA1 isoform 1

KCNA1/iso:1


"A voltage-gated potassium channel subunit KCNA1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q09470-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P10499-1

potassium voltage-gated channel subfamily A member 1 isoform 1 (rat)

rKCNA1/iso:1


"A voltage-gated potassium channel subunit KCNA1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P16388-1

potassium voltage-gated channel subfamily A member 1 isoform 1 (mouse)

mKCNA1/iso:1


"A voltage-gated potassium channel subunit KCNA1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:Q09470-1

potassium voltage-gated channel subfamily A member 1 isoform 1 (human)

hKCNA1/iso:1


"A voltage-gated potassium channel subunit KCNA1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


family



PR:000000701

modulatory voltage-gated potassium channel subunit KCNG

fam:Kchan_sub-KCNG


"A voltage-gated potassium channel alpha subunit that is a modulator of the shab-related potassium channels (Kv2). Similarly to KCNF1, KCNV and KCNS subunits, KCNG subunits are not able to form functional channels on their own. Also in common with these modulatory subunits, it lacks the conserved PxP motif located in the distal part of S6. In this class the motif is PxT. The alteration of the PxP motif seems to be an important determinant of the regulatory function of modulatory subunits." [PMID:9305895]

Yes

gene



PR:000000787

voltage-gated potassium channel KCNG1

KCNG1


"A modulatory voltage-gated potassium channel subunit KCNG that is a translation product of the human KCNG1 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:A2BDX4

voltage-gated potassium channel regulatory subunit KCNG1 (mouse)

mKCNG1


"A voltage-gated potassium channel KCNG1 that is encoded in the genome of mouse." [OMA:A2BDX4, PRO:DNx]


organism-gene



PR:D4AD53

voltage-gated potassium channel regulatory subunit KCNG1 (rat)

rKCNG1


"A voltage-gated potassium channel KCNG1 that is encoded in the genome of rat." [OMA:D4AD53, PRO:DNx]


organism-gene



PR:Q9UIX4

voltage-gated potassium channel regulatory subunit KCNG1 (human)

hKCNG1


"A voltage-gated potassium channel KCNG1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9UIX4]


organism-sequence



PR:Q9UIX4-1

voltage-gated potassium channel regulatory subunit KCNG1 isoform 1 (human)

hKCNG1/iso:1


"A voltage-gated potassium channel KCNG1 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q9UIX4-2

voltage-gated potassium channel regulatory subunit KCNG1 isoform 2 (human)

hKCNG1/iso:2


"A voltage-gated potassium channel KCNG1 isoform 2 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000000950

voltage-gated potassium channel KCNG1 isoform 1

KCNG1/iso:1


"A voltage-gated potassium channel KCNG1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UIX4-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:Q9UIX4-1

voltage-gated potassium channel regulatory subunit KCNG1 isoform 1 (human)

hKCNG1/iso:1


"A voltage-gated potassium channel KCNG1 isoform 1 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000000951

voltage-gated potassium channel KCNG1 isoform 2

KCNG1/iso:2


"A voltage-gated potassium channel KCNG1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UIX4-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:Q9UIX4-2

voltage-gated potassium channel regulatory subunit KCNG1 isoform 2 (human)

hKCNG1/iso:2


"A voltage-gated potassium channel KCNG1 isoform 2 that is encoded in the genome of human." [PRO:CNA]


gene



PR:000000788

voltage-gated potassium channel subfamily G member 3

KCNG3


"A modulatory voltage-gated potassium channel subunit KCNG that is a translation product of the human KCNG3 gene or a 1:1 ortholog thereof. It has to be associated with Kv2 subunits (PR:000000677) or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1." [PRO:CNA]


organism-gene



PR:P59053

voltage-gated potassium channel regulatory subunit KCNG3 (mouse)

mKCNG3


"A voltage-gated potassium channel subfamily G member 3 that is encoded in the genome of mouse." [OMA:P59053, PRO:DNx]


organism-sequence



PR:P59053-1

voltage-gated potassium channel regulatory subunit KCNG3 isoform 1 (mouse)

mKCNG3/iso:1


"A voltage-gated potassium channel subfamily G member 3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P59053]


organism-sequence



PR:P59053-2

voltage-gated potassium channel regulatory subunit KCNG3 isoform 2 (mouse)

mKCNG3/iso:2


"A voltage-gated potassium channel subfamily G member 3 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]


organism-gene



PR:Q8R523

voltage-gated potassium channel regulatory subunit KCNG3 (rat)

rKCNG3


"A voltage-gated potassium channel subfamily G member 3 that is encoded in the genome of rat." [OMA:Q8R523, PRO:DNx]


organism-sequence



PR:Q8R523-1

voltage-gated potassium channel regulatory subunit KCNG3 isoform 1 (rat)

rKCNG3/iso:1


"A voltage-gated potassium channel subfamily G member 3 isoform 1 that is encoded in the genome of rat." [PRO:DNx, UniProtKB:Q8R523]

Yes

organism-sequence



PR:Q8R523-2

voltage-gated potassium channel regulatory subunit KCNG3 isoform 2 (rat)

rKCNG3/iso:2


"A voltage-gated potassium channel subfamily G member 3 isoform 2 that is encoded in the genome of rat." [PRO:CNA]

Yes

organism-gene



PR:Q8TAE7

voltage-gated potassium channel regulatory subunit KCNG3 (human)

hKCNG3


"A voltage-gated potassium channel subfamily G member 3 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q8TAE7]


organism-sequence



PR:Q8TAE7-1

voltage-gated potassium channel regulatory subunit KCNG3 isoform 1 (human)

hKCNG3/iso:1


"A voltage-gated potassium channel subfamily G member 3 isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8TAE7]

Yes

organism-sequence



PR:Q8TAE7-2

voltage-gated potassium channel regulatory subunit KCNG3 isoform 2 (human)

hKCNG3/iso:2


"A voltage-gated potassium channel subfamily G member 3 isoform 2 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000076129

voltage-gated potassium channel regulatory subunit KCNG3 phosphorylated 1 (human)

hKCNG3/Phos:1


"A voltage-gated potassium channel regulatory subunit KCNG3 (human) that has been phosphorylated on the residue at the position equivalent to Thr-406 of the amino acid sequence represented by UniProtKB:Q8TAE7-1. Example: UniProtKB:Q8TAE7-1, Thr-406, MOD:00047." [IEDB_epitope:2146639, PRO:DNx]


sequence



PR:000000952

voltage-gated potassium channel subfamily G member 3 isoform 1

KCNG3/iso:1


"A voltage-gated potassium channel subfamily G member 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TAE7-1 or a 1:1 ortholog thereof." [PMID:15046870, PRO:CNA, PRO:DAN]


organism-sequence



PR:P59053-1

voltage-gated potassium channel regulatory subunit KCNG3 isoform 1 (mouse)

mKCNG3/iso:1


"A voltage-gated potassium channel subfamily G member 3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P59053]


organism-sequence



PR:Q8R523-1

voltage-gated potassium channel regulatory subunit KCNG3 isoform 1 (rat)

rKCNG3/iso:1


"A voltage-gated potassium channel subfamily G member 3 isoform 1 that is encoded in the genome of rat." [PRO:DNx, UniProtKB:Q8R523]

Yes

organism-sequence



PR:Q8TAE7-1

voltage-gated potassium channel regulatory subunit KCNG3 isoform 1 (human)

hKCNG3/iso:1


"A voltage-gated potassium channel subfamily G member 3 isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8TAE7]

Yes

sequence



PR:000000953

voltage-gated potassium channel subfamily G member 3 isoform 2

KCNG3/iso:2


"A voltage-gated potassium channel subfamily G member 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TAE7-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P59053-2

voltage-gated potassium channel regulatory subunit KCNG3 isoform 2 (mouse)

mKCNG3/iso:2


"A voltage-gated potassium channel subfamily G member 3 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]


organism-sequence



PR:Q8R523-2

voltage-gated potassium channel regulatory subunit KCNG3 isoform 2 (rat)

rKCNG3/iso:2


"A voltage-gated potassium channel subfamily G member 3 isoform 2 that is encoded in the genome of rat." [PRO:CNA]

Yes

organism-sequence



PR:Q8TAE7-2

voltage-gated potassium channel regulatory subunit KCNG3 isoform 2 (human)

hKCNG3/iso:2


"A voltage-gated potassium channel subfamily G member 3 isoform 2 that is encoded in the genome of human." [PRO:CNA]


gene



PR:000000789

voltage-gated potassium channel subfamily G member 4

KCNG4


"A modulatory voltage-gated potassium channel subunit KCNG that is a translation product of the human KCNG4 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:Q80XM3

voltage-gated potassium channel regulatory subunit KCNG4 (mouse)

mKCNG4


"A voltage-gated potassium channel subfamily G member 4 that is encoded in the genome of mouse." [OMA:Q80XM3, PRO:DNx]


organism-gene



PR:Q8TDN1

voltage-gated potassium channel regulatory subunit KCNG4 (human)

hKCNG4


"A voltage-gated potassium channel subfamily G member 4 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q8TDN1]


organism-sequence



PR:Q8TDN1-1

voltage-gated potassium channel regulatory subunit KCNG4 isoform 1 (human)

hKCNG4/iso:1


"A voltage-gated potassium channel subfamily G member 4 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q8TDN1-2

voltage-gated potassium channel regulatory subunit KCNG4 isoform h2 (human)

hKCNG4/iso:h2


"A voltage-gated potassium channel regulatory subunit KCNG4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TDN1-2." [PRO:DNx, UniProtKB:Q8TDN1]


sequence



PR:000000954

voltage-gated potassium channel subfamily G member 4 isoform 1

KCNG4/iso:1


"A voltage-gated potassium channel subfamily G member 4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TDN1-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:Q8TDN1-1

voltage-gated potassium channel regulatory subunit KCNG4 isoform 1 (human)

hKCNG4/iso:1


"A voltage-gated potassium channel subfamily G member 4 isoform 1 that is encoded in the genome of human." [PRO:CNA]


gene



PR:000009259

voltage-gated potassium channel KCNG2

KCNG2


"A modulatory voltage-gated potassium channel subunit KCNG that is a translation product of the human KCNG2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O73606

voltage-gated potassium channel regulatory subunit KCNG2 (chicken)

chick-KCNG2


"A voltage-gated potassium channel KCNG2 that is encoded in the genome of chicken." [OMA:O73606, PRO:DNx]


organism-gene



PR:Q9QYU3

voltage-gated potassium channel regulatory subunit KCNG2 (rat)

rKCNG2


"A voltage-gated potassium channel KCNG2 that is encoded in the genome of rat." [OMA:Q9QYU3, PRO:DNx]


organism-gene



PR:Q9UJ96

voltage-gated potassium channel regulatory subunit KCNG2 (human)

hKCNG2


"A voltage-gated potassium channel KCNG2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UJ96]


family



PR:000000702

modulatory voltage-gated potassium channel subunit KCNS

fam:Kchan_sub-KCNS


"A voltage-gated potassium channel alpha subunit that is a modulator of the shab-related potassium channels (Kv2). Similarly to KCNF1, KCNV and KCNG subunits, KCNS subunits are not able to form functional channels on their own. Also in common with these modulatory subunits, it lacks the conserved PxP motif located in the distal part of S6. In this class the motif is PIT. The alteration of the PxP motif seems to be an important determinant of the regulatory function of modulatory subunits." [PMID:12642579, PMID:9305895]

Yes

gene



PR:000000798

voltage-gated potassium channel KCNS1

KCNS1


"A modulatory voltage-gated potassium channel subunit KCNS that is a translation product of the human KCNS1 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:O35173

delayed-rectifier potassium channel regulatory subunit KCNS1 (mouse)

mKCNS1


"A voltage-gated potassium channel KCNS1 that is encoded in the genome of mouse." [OMA:O35173, PRO:DNx]


organism-sequence



PR:O35173-1

potassium voltage-gated channel subfamily S member 1 isoform 1 (mouse)

mKCNS1/iso:1


"A voltage-gated potassium channel KCNS1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-gene



PR:O88758

delayed-rectifier potassium channel regulatory subunit KCNS1 (rat)

rKCNS1


"A voltage-gated potassium channel KCNS1 that is encoded in the genome of rat." [OMA:O88758, PRO:DNx]


organism-gene



PR:Q96KK3

delayed-rectifier potassium channel regulatory subunit KCNS1 (human)

hKCNS1


"A voltage-gated potassium channel KCNS1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q96KK3]


organism-sequence



PR:Q96KK3-1

delayed-rectifier potassium channel regulatory subunit KCNS1 isoform 1 (human)

hKCNS1/iso:1


"A voltage-gated potassium channel KCNS1 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

sequence



PR:000000969

voltage-gated potassium channel KCNS1 isoform 1

KCNS1/iso:1


"A voltage-gated potassium channel KCNS1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96KK3-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:O35173-1

potassium voltage-gated channel subfamily S member 1 isoform 1 (mouse)

mKCNS1/iso:1


"A voltage-gated potassium channel KCNS1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-sequence



PR:Q96KK3-1

delayed-rectifier potassium channel regulatory subunit KCNS1 isoform 1 (human)

hKCNS1/iso:1


"A voltage-gated potassium channel KCNS1 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

gene



PR:000000799

voltage-gated potassium channel KCNS2

KCNS2


"A modulatory voltage-gated potassium channel subunit KCNS that is a translation product of the human KCNS2 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:O35174

delayed-rectifier potassium channel regulatory subunit KCNS2 (mouse)

mKCNS2


"A voltage-gated potassium channel KCNS2 that is encoded in the genome of mouse." [OMA:O35174, PRO:DNx]


organism-sequence



PR:O35174-1

potassium voltage-gated channel subfamily S member 2 isoform 1 (mouse)

mKCNS2/iso:1


"A voltage-gated potassium channel KCNS2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-gene



PR:Q9ER26

delayed-rectifier potassium channel regulatory subunit KCNS2 (rat)

rKCNS2


"A voltage-gated potassium channel KCNS2 that is encoded in the genome of rat." [OMA:Q9ER26, PRO:DNx]


organism-gene



PR:Q9ULS6

delayed-rectifier potassium channel regulatory subunit KCNS2 (human)

hKCNS2


"A voltage-gated potassium channel KCNS2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9ULS6]


organism-sequence



PR:Q9ULS6-1

delayed-rectifier potassium channel regulatory subunit KCNS2 isoform 1 (human)

hKCNS2/iso:1


"A voltage-gated potassium channel KCNS2 isoform 1 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000000970

voltage-gated potassium channel KCNS2 isoform 1

KCNS2/iso:1


"A voltage-gated potassium channel KCNS2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35174-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:O35174-1

potassium voltage-gated channel subfamily S member 2 isoform 1 (mouse)

mKCNS2/iso:1


"A voltage-gated potassium channel KCNS2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-sequence



PR:Q9ULS6-1

delayed-rectifier potassium channel regulatory subunit KCNS2 isoform 1 (human)

hKCNS2/iso:1


"A voltage-gated potassium channel KCNS2 isoform 1 that is encoded in the genome of human." [PRO:CNA]


gene



PR:000000800

voltage-gated potassium channel KCNS3

KCNS3


"A modulatory voltage-gated potassium channel subunit KCNS that is a translation product of the human KCNS3 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:O88759

delayed-rectifier potassium channel regulatory subunit KCNS3 (rat)

rKCNS3


"A voltage-gated potassium channel KCNS3 that is encoded in the genome of rat." [OMA:O88759, PRO:DNx]


organism-sequence



PR:O88759-1

potassium voltage-gated channel subfamily S member 3 isoform 1 (rat)

rKCNS3/iso:1


"A voltage-gated potassium channel KCNS3 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:Q8BQZ8

delayed-rectifier potassium channel regulatory subunit KCNS3 (mouse)

mKCNS3


"A voltage-gated potassium channel KCNS3 that is encoded in the genome of mouse." [OMA:Q8BQZ8, PRO:DNx]


organism-sequence



PR:Q8BQZ8-1

potassium voltage-gated channel subfamily S member 3 isoform 1 (mouse)

mKCNS3/iso:1


"A voltage-gated potassium channel KCNS3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:Q9BQ31

delayed-rectifier potassium channel regulatory subunit KCNS3 (human)

hKCNS3


"A voltage-gated potassium channel KCNS3 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9BQ31]


organism-sequence



PR:Q9BQ31-1

delayed-rectifier potassium channel regulatory subunit KCNS3 isoform 1 (human)

hKCNS3/iso:1


"A voltage-gated potassium channel KCNS3 isoform 1 that is encoded in the genome of human." [PRO:DNx]


sequence



PR:000042822

voltage-gated potassium channel KCNS3 isoform 1

KCNS3/iso:1


"A voltage-gated potassium channel KCNS3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BQ31-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:O88759-1

potassium voltage-gated channel subfamily S member 3 isoform 1 (rat)

rKCNS3/iso:1


"A voltage-gated potassium channel KCNS3 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:Q8BQZ8-1

potassium voltage-gated channel subfamily S member 3 isoform 1 (mouse)

mKCNS3/iso:1


"A voltage-gated potassium channel KCNS3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:Q9BQ31-1

delayed-rectifier potassium channel regulatory subunit KCNS3 isoform 1 (human)

hKCNS3/iso:1


"A voltage-gated potassium channel KCNS3 isoform 1 that is encoded in the genome of human." [PRO:DNx]


family



PR:000000709

shaker-related voltage-gated potassium channel alpha subunit

fam:Kchan_shaker_sub-a


"A voltage-gated potassium channel alpha subunit that is a member of the subfamily A of voltage-gated potassium channels. The N terminus is rich in basic residues and this region is critical for the N-type inactivation. Shaker-related voltage-gated potassium channels (Kv1 channels) play an important role in modulating electrical excitability of axons." [PMID:11506885]


gene



PR:000000809

voltage-gated potassium channel subunit KCNA10

KCNA10


"A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA10 gene or a 1:1 ortholog thereof. It is a subunit of the Kv1.8 channel is a delayed rectifier channel that may be involved in regulating the tone of renal vascular smooth muscle and may also participate in the cardiac action potential. It is regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. It can coassemble with other Kv1 subunits." [PMID:10836990]


organism-gene



PR:B2RQA1

potassium voltage-gated channel subfamily A member 10 (mouse)

mKCNA10


"A voltage-gated potassium channel subunit KCNA10 that is encoded in the genome of mouse." [OMA:B2RQA1, PRO:DNx]


organism-gene



PR:Q16322

potassium voltage-gated channel subfamily A member 10 (human)

hKCNA10


"A voltage-gated potassium channel subunit KCNA10 that is encoded in the genome of human." []


organism-sequence



PR:Q16322-1

potassium voltage-gated channel subfamily A member 10 isoform 1 (human)

hKCNA10/iso:1


"A voltage-gated potassium channel subunit KCNA10 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-gene



PR:Q7T199

potassium voltage-gated channel subfamily A member 10 (chicken)

chick-KCNA10


"A voltage-gated potassium channel subunit KCNA10 that is encoded in the genome of chicken." [PRO:DNx, UniProtKB:Q7T199]


sequence



PR:000000971

voltage-gated potassium channel subunit KCNA10 isoform 1

KCNA10/iso:1


"A voltage-gated potassium channel subunit KCNA10 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16322-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:Q16322-1

potassium voltage-gated channel subfamily A member 10 isoform 1 (human)

hKCNA10/iso:1


"A voltage-gated potassium channel subunit KCNA10 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

gene



PR:000000810

voltage-gated potassium channel subunit KCNA2

KCNA2


"A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA2 gene or a 1:1 ortholog thereof. The Kv1.2 channel is involved in maintaining membrane potential, modulating electrical excitability in neurons and muscle. It can coassemble with other Kv1 subunits." [PMID:16382104]


organism-gene



PR:P16389

potassium voltage-gated channel subfamily A member 2 (human)

hKCNA2


"A voltage-gated potassium channel subunit KCNA2 that is encoded in the genome of human." []


organism-sequence



PR:P16389-1

potassium voltage-gated channel subfamily A member 2 isoform 1 (human)

hKCNA2/iso:1


"A voltage-gated potassium channel subunit KCNA2 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036584

voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 (human)

hKCNA2/iso:1/Phos:1


"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 in human. UniProtKB:P16389-1, Tyr-132, MOD:00048." [PMID:15215309, PRO:CNA]

Yes

organism-modification



PR:000036587

voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (human)

hKCNA2/iso:1/Phos:2


"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 in human. UniProtKB:P16389-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633, PRO:CNA]

Yes

organism-sequence



PR:P16389-2

potassium voltage-gated channel subfamily A member 2 isoform h2 (human)

hKCNA2/iso:h2


"A potassium voltage-gated channel subfamily A member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16389-2." [PRO:DNx, UniProtKB:P16389]


organism-gene



PR:P63141

potassium voltage-gated channel subfamily A member 2 (mouse)

mKCNA2


"A voltage-gated potassium channel subunit KCNA2 that is encoded in the genome of mouse." [OMA:P63141, PRO:DNx]


organism-sequence



PR:P63141-1

potassium voltage-gated channel subfamily A member 2 isoform 1 (mouse)

mKCNA2/iso:1


"A voltage-gated potassium channel subunit KCNA2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-modification



PR:000036585

voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (mouse)

mKCNA2/iso:1/Phos:2


"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 in mouse. UniProtKB:P63141-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633, PRO:CNA, PRO:DAN]

Yes

organism-gene



PR:P63142

potassium voltage-gated channel subfamily A member 2 (rat)

rKCNA2


"A voltage-gated potassium channel subunit KCNA2 that is encoded in the genome of rat." [OMA:P63142, PRO:DNx]


organism-sequence



PR:P63142-1

potassium voltage-gated channel subfamily A member 2 isoform 1 (rat)

rKCNA2/iso:1


"A voltage-gated potassium channel subunit KCNA2 isoform 1 that is encoded in the genome of rat." [PRO:CNA]

Yes

organism-modification



PR:000036586

voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (rat)

rKCNA2/iso:1/Phos:2


"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 in rat. UniProtKB:P63142-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633, PRO:CNA, PRO:DAN]

Yes

organism-gene



PR:Q8I4B0

potassium voltage-gated channel protein shk-1 (worm)

KCNA2 (worm)


"A voltage-gated potassium channel subunit KCNA2 that is encoded in the genome of worm." [OMA:Q8I4B0, PRO:DNx]


organism-sequence



PR:Q8I4B0-1

potassium voltage-gated channel protein shk-1 isoform c (worm)

KCNA2/iso:c (worm)


"A potassium voltage-gated channel protein shk-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8I4B0-1." [PRO:DNx, UniProtKB:Q8I4B0]


organism-sequence



PR:Q8I4B0-2

potassium voltage-gated channel protein shk-1 isoform b (worm)

KCNA2/iso:b (worm)


"A potassium voltage-gated channel protein shk-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8I4B0-2." [PRO:DNx, UniProtKB:Q8I4B0]


organism-sequence



PR:Q8I4B0-3

potassium voltage-gated channel protein shk-1 isoform d (worm)

KCNA2/iso:d (worm)


"A potassium voltage-gated channel protein shk-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8I4B0-3." [PRO:DNx, UniProtKB:Q8I4B0]


organism-sequence



PR:Q8I4B0-4

potassium voltage-gated channel protein shk-1 isoform a (worm)

KCNA2/iso:a (worm)


"A potassium voltage-gated channel protein shk-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8I4B0-4." [PRO:DNx, UniProtKB:Q8I4B0]


organism-sequence



PR:Q8I4B0-5

potassium voltage-gated channel protein shk-1 isoform e (worm)

KCNA2/iso:e (worm)


"A potassium voltage-gated channel protein shk-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8I4B0-5." [PRO:DNx, UniProtKB:Q8I4B0]


organism-sequence



PR:Q8I4B0-6

potassium voltage-gated channel protein shk-1 isoform f (worm)

KCNA2/iso:f (worm)


"A potassium voltage-gated channel protein shk-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8I4B0-6." [PRO:DNx, UniProtKB:Q8I4B0]


organism-sequence



PR:Q8I4B0-7

potassium voltage-gated channel protein shk-1 isoform g (worm)

KCNA2/iso:g (worm)


"A potassium voltage-gated channel protein shk-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8I4B0-7." [PRO:DNx, UniProtKB:Q8I4B0]


sequence



PR:000000972

voltage-gated potassium channel subunit KCNA2 isoform 1

KCNA2/iso:1


"A voltage-gated potassium channel subunit KCNA2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16389-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P16389-1

potassium voltage-gated channel subfamily A member 2 isoform 1 (human)

hKCNA2/iso:1


"A voltage-gated potassium channel subunit KCNA2 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036584

voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 (human)

hKCNA2/iso:1/Phos:1


"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 in human. UniProtKB:P16389-1, Tyr-132, MOD:00048." [PMID:15215309, PRO:CNA]

Yes

organism-modification



PR:000036587

voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (human)

hKCNA2/iso:1/Phos:2


"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 in human. UniProtKB:P16389-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633, PRO:CNA]

Yes

organism-sequence



PR:P63141-1

potassium voltage-gated channel subfamily A member 2 isoform 1 (mouse)

mKCNA2/iso:1


"A voltage-gated potassium channel subunit KCNA2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-modification



PR:000036585

voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (mouse)

mKCNA2/iso:1/Phos:2


"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 in mouse. UniProtKB:P63141-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633, PRO:CNA, PRO:DAN]

Yes

organism-sequence



PR:P63142-1

potassium voltage-gated channel subfamily A member 2 isoform 1 (rat)

rKCNA2/iso:1


"A voltage-gated potassium channel subunit KCNA2 isoform 1 that is encoded in the genome of rat." [PRO:CNA]

Yes

organism-modification



PR:000036586

voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (rat)

rKCNA2/iso:1/Phos:2


"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 in rat. UniProtKB:P63142-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633, PRO:CNA, PRO:DAN]

Yes

modification



PR:000000991

voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated form

KCNA2/iso:1/PhosRes+


"A voltage-gated potassium channel subunit KCNA2 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000001000

voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1

KCNA2/iso:1/Phos:1


"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated form in which the phosphorylation occurs at the Tyr residue within the REDEGYIK sequence located adjacent to the tetramerization domain. Phosphorylation at this site promotes endocytosis and suppresses the channel activity. Example: UniProtKB:P16389-1, Tyr-132, MOD:00048." [PRO:CNA]


organism-modification



PR:000036584

voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 (human)

hKCNA2/iso:1/Phos:1


"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 in human. UniProtKB:P16389-1, Tyr-132, MOD:00048." [PMID:15215309, PRO:CNA]

Yes

modification



PR:000001001

voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2

KCNA2/iso:1/Phos:2


"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated form in which the phosphorylation occurs at the pair of Ser residues within the SSPD motif at the C terminus. Phosphorylation at this site promotes cell surface localization. Example: UniProtKB:P16389-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633]


organism-modification



PR:000036585

voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (mouse)

mKCNA2/iso:1/Phos:2


"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 in mouse. UniProtKB:P63141-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036586

voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (rat)

rKCNA2/iso:1/Phos:2


"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 in rat. UniProtKB:P63142-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036587

voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (human)

hKCNA2/iso:1/Phos:2


"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 in human. UniProtKB:P16389-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633, PRO:CNA]

Yes

gene



PR:000000811

voltage-gated potassium channel subunit KCNA3

KCNA3


"A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA3 gene or a 1:1 ortholog thereof. The Kv1.3 channel is involved in maintaining membrane potential and calcium signaling in lymphocytes and oligodendrocytes. It can coassemble with other Kv1 subunits." [PRO:CNA]


organism-gene



PR:P15384

potassium voltage-gated channel subfamily A member 3 (rat)

rKCNA3


"A voltage-gated potassium channel subunit KCNA3 that is encoded in the genome of rat." [OMA:P15384, PRO:DNx]


organism-gene



PR:P16390

potassium voltage-gated channel subfamily A member 3 (mouse)

mKCNA3


"A voltage-gated potassium channel subunit KCNA3 that is encoded in the genome of mouse." [OMA:P16390, PRO:DNx]


organism-gene



PR:P22001

potassium voltage-gated channel subfamily A member 3 (human)

hKCNA3


"A voltage-gated potassium channel subunit KCNA3 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P22001]


organism-sequence



PR:P22001-1

potassium voltage-gated channel subfamily A member 3 isoform 1 (human)

hKCNA3/iso:1


"A voltage-gated potassium channel subunit KCNA3 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036639

voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated 1 (human)

hKCNA3/iso:1/Phos:1


"A voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated 1 in human." [PMID:9989602, PRO:CL]

Yes

organism-modification



PR:000044708

voltage-gated potassium channel subunit KCNA3 isoform 1 unmodified form (human)

hKCNA3/iso:1/UnMod


"A voltage-gated potassium channel subunit KCNA3 isoform 1 unmodified form in human." [PRO:DNx]

Yes

organism-sequence



PR:P22001-4

potassium voltage-gated channel subfamily A member 3 isoform h2 (human)

hKCNA3/iso:h2


"A potassium voltage-gated channel subfamily A member 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22001-4." [PRO:DNx, UniProtKB:P22001]


organism-sequence



PR:P22001-5

potassium voltage-gated channel subfamily A member 3 isoform h3 (human)

hKCNA3/iso:h3


"A potassium voltage-gated channel subfamily A member 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22001-5." [PRO:DNx, UniProtKB:P22001]


organism-modification



PR:000065955

potassium voltage-gated channel subfamily A member 3 deaminated 1 (human)

hKCNA3/Deam:1


"A potassium voltage-gated channel subfamily A member 3 (human) that has been deaminated on the residue at the position equivalent to Asn-109 of the amino acid sequence represented by UniProtKB:P22001. UniProtKB:P22001, Asn-109, MOD:00684." [IEDB_epitope:1752498, PRO:DNx]


sequence



PR:000000973

voltage-gated potassium channel subunit KCNA3 isoform 1

KCNA3/iso:1


"A voltage-gated potassium channel subunit KCNA3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22001-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P22001-1

potassium voltage-gated channel subfamily A member 3 isoform 1 (human)

hKCNA3/iso:1


"A voltage-gated potassium channel subunit KCNA3 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036639

voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated 1 (human)

hKCNA3/iso:1/Phos:1


"A voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated 1 in human." [PMID:9989602, PRO:CL]

Yes

organism-modification



PR:000044708

voltage-gated potassium channel subunit KCNA3 isoform 1 unmodified form (human)

hKCNA3/iso:1/UnMod


"A voltage-gated potassium channel subunit KCNA3 isoform 1 unmodified form in human." [PRO:DNx]

Yes

modification



PR:000002682

voltage-gated potassium channel subunit KCNA3 isoform 1 unmodified form

KCNA3/iso:1/UnMod


"A voltage-gated potassium channel subunit KCNA3 isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]


organism-modification



PR:000044708

voltage-gated potassium channel subunit KCNA3 isoform 1 unmodified form (human)

hKCNA3/iso:1/UnMod


"A voltage-gated potassium channel subunit KCNA3 isoform 1 unmodified form in human." [PRO:DNx]

Yes

modification



PR:000003223

voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated form

KCNA3/iso:1/PhosRes+


"A voltage-gated potassium channel subunit KCNA3 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000003224

voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated 1

KCNA3/iso:1/Phos:1


"A voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated form in which the phosphorylation occurs as a result of the interaction of HIV gp160 with CD4. Probably phosphorylated by PKC." [PMID:9989602, PRO:CL]


organism-modification



PR:000036639

voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated 1 (human)

hKCNA3/iso:1/Phos:1


"A voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated 1 in human." [PMID:9989602, PRO:CL]

Yes

gene



PR:000000812

voltage-gated potassium channel subunit KCNA5

KCNA5


"A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA5 gene or a 1:1 ortholog thereof. The voltage-gated potassium channel Kv1.5 mediates the ultrarapid-activating potassium current (IKur) in heart, and also plays a critical role in the regulation of arterial tone." [PMID:10575199, PMID:16772329, PMID:18344374]


organism-gene



PR:P19024

potassium voltage-gated channel subfamily A member 5 (rat)

rKCNA5


"A voltage-gated potassium channel subunit KCNA5 that is encoded in the genome of rat." [OMA:P19024, PRO:DNx]


organism-gene



PR:P22460

potassium voltage-gated channel subfamily A member 5 (human)

hKCNA5


"A voltage-gated potassium channel subunit KCNA5 that is encoded in the genome of human." []


organism-sequence



PR:P22460-1

potassium voltage-gated channel subfamily A member 5 isoform 1 (human)

hKCNA5/iso:1


"A voltage-gated potassium channel subunit KCNA5 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-sequence



PR:000036568

potassium voltage-gated channel subfamily A member 5 isoform 1 sequence variant E375* (human)

hKCNA5/iso:1/var:E375*


"A potassium voltage-gated channel subfamily A member 5 isoform 1 (human) that has a C-terminal truncation and thus lacks the S4-S6 voltage sensor, pore region and C terminus, but preserves the N terminus and S1-S3 transmembrane domains that secure tetrameric subunit assembly. UniProtKB:P22460-1, 1-374." [PMID:16772329, PRO:CNA]

Yes

organism-sequence



PR:P22460-2

potassium voltage-gated channel subfamily A member 5 isoform h2 (human)

hKCNA5/iso:h2


"A potassium voltage-gated channel subfamily A member 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22460-2." [PRO:DNx, UniProtKB:P22460]


organism-gene



PR:Q61762

potassium voltage-gated channel subfamily A member 5 (mouse)

mKCNA5


"A voltage-gated potassium channel subunit KCNA5 that is encoded in the genome of mouse." [OMA:Q61762, PRO:DNx]


organism-sequence



PR:Q61762-1

potassium voltage-gated channel subfamily A member 5 isoform 1 (mouse)

mKCNA5/iso:1


"A voltage-gated potassium channel subunit KCNA5 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-sequence



PR:Q61762-2

potassium voltage-gated channel subfamily A member 5 isoform 2 (mouse)

mKCNA5/iso:2


"A voltage-gated potassium channel subunit KCNA5 isoform 2 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:Q61762]

Yes

organism-sequence



PR:Q61762-3

potassium voltage-gated channel subfamily A member 5 isoform 3 (mouse)

mKCNA5/iso:3


"A voltage-gated potassium channel subunit KCNA5 isoform 3 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:Q61762]

Yes

sequence



PR:000000974

voltage-gated potassium channel subunit KCNA5 isoform 1

KCNA5/iso:1


"A voltage-gated potassium channel subunit KCNA5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22460-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P22460-1

potassium voltage-gated channel subfamily A member 5 isoform 1 (human)

hKCNA5/iso:1


"A voltage-gated potassium channel subunit KCNA5 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-sequence



PR:000036568

potassium voltage-gated channel subfamily A member 5 isoform 1 sequence variant E375* (human)

hKCNA5/iso:1/var:E375*


"A potassium voltage-gated channel subfamily A member 5 isoform 1 (human) that has a C-terminal truncation and thus lacks the S4-S6 voltage sensor, pore region and C terminus, but preserves the N terminus and S1-S3 transmembrane domains that secure tetrameric subunit assembly. UniProtKB:P22460-1, 1-374." [PMID:16772329, PRO:CNA]

Yes

organism-sequence



PR:Q61762-1

potassium voltage-gated channel subfamily A member 5 isoform 1 (mouse)

mKCNA5/iso:1


"A voltage-gated potassium channel subunit KCNA5 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

sequence



PR:000000975

voltage-gated potassium channel subunit KCNA5 isoform 2

KCNA5/iso:2


"A voltage-gated potassium channel subunit KCNA5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61762-2 or a 1:1 ortholog thereof." [PMID:11524461, PMID:8226976, PRO:CNA, PRO:DAN]


organism-sequence



PR:Q61762-2

potassium voltage-gated channel subfamily A member 5 isoform 2 (mouse)

mKCNA5/iso:2


"A voltage-gated potassium channel subunit KCNA5 isoform 2 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:Q61762]

Yes

modification



PR:000002684

voltage-gated potassium channel subunit KCNA5 isoform 2 unmodified form

KCNA5/iso:2/UnMod


"A voltage-gated potassium channel subunit KCNA5 isoform 2 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]

Yes

sequence



PR:000000976

voltage-gated potassium channel subunit KCNA5 isoform 3

KCNA5/iso:3


"A voltage-gated potassium channel subunit KCNA5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61762-3 or a 1:1 ortholog thereof." [PMID:8226976, PRO:CNA, PRO:DAN]


organism-sequence



PR:Q61762-3

potassium voltage-gated channel subfamily A member 5 isoform 3 (mouse)

mKCNA5/iso:3


"A voltage-gated potassium channel subunit KCNA5 isoform 3 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:Q61762]

Yes

gene



PR:000000813

voltage-gated potassium channel subunit KCNA6

KCNA6


"A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA6 gene or a 1:1 ortholog thereof. The Kv1.6 channel is Regulator of membrane potential in neurons. The N terminus contains an N terminus inactivation prevention domain. It can coassemble with other Kv1 subunits." [PRO:CNA]


organism-gene



PR:P17658

potassium voltage-gated channel subfamily A member 6 (human)

hKCNA6


"A voltage-gated potassium channel subunit KCNA6 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P17658]


organism-sequence



PR:P17658-1

potassium voltage-gated channel subfamily A member 6 isoform 1 (human)

hKCNA6/iso:1


"A voltage-gated potassium channel subunit KCNA6 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-gene



PR:P17659

potassium voltage-gated channel subfamily A member 6 (rat)

rKCNA6


"A voltage-gated potassium channel subunit KCNA6 that is encoded in the genome of rat." [OMA:P17659, PRO:DNx]


organism-gene



PR:Q61923

potassium voltage-gated channel subfamily A member 6 (mouse)

mKCNA6


"A voltage-gated potassium channel subunit KCNA6 that is encoded in the genome of mouse." [OMA:Q61923, PRO:DNx]


organism-sequence



PR:Q61923-1

potassium voltage-gated channel subfamily A member 6 isoform 1 (mouse)

mKCNA6/iso:1


"A voltage-gated potassium channel subunit KCNA6 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


sequence



PR:000000978

voltage-gated potassium channel subunit KCNA6 isoform 1

KCNA6/iso:1


"A voltage-gated potassium channel subunit KCNA6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17658-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P17658-1

potassium voltage-gated channel subfamily A member 6 isoform 1 (human)

hKCNA6/iso:1


"A voltage-gated potassium channel subunit KCNA6 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q61923-1

potassium voltage-gated channel subfamily A member 6 isoform 1 (mouse)

mKCNA6/iso:1


"A voltage-gated potassium channel subunit KCNA6 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


gene



PR:000000814

voltage-gated potassium channel subunit KCNA7

KCNA7


"A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA7 gene or a 1:1 ortholog thereof. The Kv1.7 channel has properties similar to the ultrarapidly activating IKur current in the heart. It can coassemble with other Kv1 subunits." [PRO:CNA]


organism-gene



PR:Q17ST2

potassium voltage-gated channel subfamily A member 7 (mouse)

mKCNA7


"A voltage-gated potassium channel subunit KCNA7 that is encoded in the genome of mouse." [OMA:Q17ST2, PRO:DNx]


organism-sequence



PR:Q17ST2-1

potassium voltage-gated channel subfamily A member 7 isoform 1 (mouse)

mKCNA7/iso:1


"A voltage-gated potassium channel subunit KCNA7 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-sequence



PR:Q17ST2-2

potassium voltage-gated channel subfamily A member 7 isoform 2 (mouse)

mKCNA7/iso:2


"A voltage-gated potassium channel subunit KCNA7 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-gene



PR:Q96RP8

potassium voltage-gated channel subfamily A member 7 (human)

hKCNA7


"A voltage-gated potassium channel subunit KCNA7 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q96RP8]


organism-sequence



PR:Q96RP8-1

potassium voltage-gated channel subfamily A member 7 isoform 1 (human)

hKCNA7/iso:1


"A voltage-gated potassium channel subunit KCNA7 isoform 2 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000069415

potassium voltage-gated channel subfamily A member 7 phosphorylated 1 (human)

hKCNA7/Phos:1


"A potassium voltage-gated channel subfamily A member 7 (human) that has been phosphorylated on the residue at the position equivalent to Ser-308 of the amino acid sequence represented by UniProtKB:Q96RP8. UniProtKB:Q96RP8, Ser-308, MOD:00046." [IEDB_epitope:2148639, PRO:DNx]


sequence



PR:000000979

voltage-gated potassium channel subunit KCNA7 isoform 1

KCNA7/iso:1


"A voltage-gated potassium channel subunit KCNA7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q17ST2-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:Q17ST2-1

potassium voltage-gated channel subfamily A member 7 isoform 1 (mouse)

mKCNA7/iso:1


"A voltage-gated potassium channel subunit KCNA7 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

sequence



PR:000000980

voltage-gated potassium channel subunit KCNA7 isoform 2

KCNA7/iso:2


"A voltage-gated potassium channel subunit KCNA7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q17ST2-2 or a 1:1 ortholog thereof. This form contributes to channels that are slow-inactivating and redox-insensitive." [PRO:CNA, PRO:DAN]


organism-sequence



PR:Q17ST2-2

potassium voltage-gated channel subfamily A member 7 isoform 2 (mouse)

mKCNA7/iso:2


"A voltage-gated potassium channel subunit KCNA7 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-sequence



PR:Q96RP8-1

potassium voltage-gated channel subfamily A member 7 isoform 1 (human)

hKCNA7/iso:1


"A voltage-gated potassium channel subunit KCNA7 isoform 2 that is encoded in the genome of human." [PRO:CNA]


family



PR:000000710

shal-related voltage-gated potassium channel alpha subunit

fam:Kchan_shal_sub-a


"A voltage-gated potassium channel alpha subunit that is a constituent of the Kv4 channels, responsible for transient, voltage-dependent potassium currents (A currents) in the brain and heart. The unique motif KSCASE is absolutely conserved in all shal-related channel subunits. Mutations in this region drastically affect deactivation and inactivation. This motif is located in the cytoplasmic S4-S5 loop. In common with Kv2 and Kv3 channels, the tetramerization domain at the N terminus contains a zinc binding site. Kv.4 channels are modulated by Kv4 Channel Interacting Proteins (KChIPs1-4), which bind to the cytoplasmic N-terminal domain." [PMID:15555915]


gene



PR:000000784

voltage-gated potassium channel KCND1

KCND1


"A shal-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCND1 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:Q03719

A-type voltage-gated potassium channel KCND1 (mouse)

mKCND1


"A voltage-gated potassium channel KCND1 that is encoded in the genome of mouse." [OMA:Q03719, PRO:DNx]


organism-gene



PR:Q9NSA2

A-type voltage-gated potassium channel KCND1 (human)

hKCND1


"A voltage-gated potassium channel KCND1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9NSA2]


organism-sequence



PR:Q9NSA2-1

A-type voltage-gated potassium channel KCND1 isoform h1 (human)

hKCND1/iso:h1


"An A-type voltage-gated potassium channel KCND1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NSA2-1." [PRO:DNx, UniProtKB:Q9NSA2]


organism-sequence



PR:Q9NSA2-2

A-type voltage-gated potassium channel KCND1 isoform h2 (human)

hKCND1/iso:h2


"An A-type voltage-gated potassium channel KCND1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NSA2-2." [PRO:DNx, UniProtKB:Q9NSA2]


gene



PR:000000785

A-type voltage-gated potassium channel KCND2

KCND2


"A shal-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCND2 gene or a 1:1 ortholog thereof. Kv4.2 potassium channels play a critical role in postsynaptic excitability. They are modulated by phosphorylation as well as by association with Kv4 Channel Interacting Proteins (KChIPs). The N terminus contains an ER retention motif RKR that seems to be masked when associated to KChiPs. This masking increases surface expression." [PMID:12829703, PRO:CNA]


organism-gene



PR:Q5VSI1

A-type voltage-gated potassium channel KCND2 (zebrafish)

z-KCND2


"An A-type voltage-gated potassium channel KCND2 that is encoded in the genome of zebrafish." [PRO:CNA]


organism-gene



PR:Q9NZV8

A-type voltage-gated potassium channel KCND2 (human)

hKCND2


"An A-type voltage-gated potassium channel KCND2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9NZV8]


organism-sequence



PR:Q9NZV8-1

A-type voltage-gated potassium channel KCND2 isoform 1 (human)

hKCND2/iso:1


"An A-type voltage-gated potassium channel KCND2 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000084839

A-type voltage-gated potassium channel KCND2 deaminated 1 (human)

hKCND2/Deam:1


"An A-type voltage-gated potassium channel KCND2 (human) that has been deaminated on the residue at the position equivalent to Gln-554 of the amino acid sequence represented by UniProtKB:Q9NZV8. UniProtKB:Q9NZV8, Gln-554, MOD:00685." [IEDB_epitope:1823778, PRO:DNx]


organism-gene



PR:Q9Z0V2

A-type voltage-gated potassium channel KCND2 (mouse)

mKCND2


"An A-type voltage-gated potassium channel KCND2 that is encoded in the genome of mouse." [OMA:Q9Z0V2, PRO:DNx]


organism-sequence



PR:Q9Z0V2-1

A-type voltage-gated potassium channel KCND2 isoform 1 (mouse)

mKCND2/iso:1


"An A-type voltage-gated potassium channel KCND2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-modification



PR:000036577

A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 1 (mouse)

mKCND2/iso:1/Phos:1


"An A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q9Z0V2-1, Thr-38, MOD:00047|Ser-552, MOD:00046." [PMID:10681507, PRO:CNA]


organism-modification



PR:000036578

A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 2 (mouse)

mKCND2/iso:1/Phos:2


"An A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 2 in mouse. UniProtKB:Q9Z0V2-1, Thr-38, MOD:00047." [PMID:11040264, PRO:CNA]

Yes

organism-modification



PR:000036579

A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 3 (mouse)

mKCND2/iso:1/Phos:3


"An A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 3 in mouse. UniProtKB:Q9Z0V2-1, Ser-552, MOD:00046." [PMID:11040264, PRO:CNA]

Yes

organism-modification



PR:000036580

A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 4 (mouse)

mKCND2/iso:1/Phos:4


"An A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 4 in mouse. UniProtKB:Q9Z0V2-1, Thr-602/Thr-607, MOD:00047|Ser-616, MOD:00046." [PMID:11040264, PMID:16251476, PRO:CNA]

Yes

organism-modification



PR:000045389

A-type voltage-gated potassium channel KCND2 isoform 1 unphosphorylated 3 (mouse)

mKCND2/iso:1/UnPhos:3


"An A-type voltage-gated potassium channel KCND2 isoform 1 (mouse) that lacks phosphorylation on Ser-552. UniProtKB:Q9Z0V2-1, Ser-552, PR:000026291." [PMID:12829703, PRO:CNA]

Yes

organism-modification



PR:000045390

A-type voltage-gated potassium channel KCND2 isoform 1 unphosphorylated 4 (mouse)

mKCND2/iso:1/UnPhos:4


"An A-type voltage-gated potassium channel KCND2 isoform 1 (mouse) that lacks phosphorylation on Thr-602, Thr-607, and Ser-616. UniProtKB:Q9Z0V2-1, Thr-602/Thr-607/Ser-616, PR:000026291." [PMID:16251476, PRO:CNA]

Yes

sequence



PR:000000947

A-type voltage-gated potassium channel KCND2 isoform 1

KCND2/iso:1


"An A-type voltage-gated potassium channel KCND2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZV8-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:Q9NZV8-1

A-type voltage-gated potassium channel KCND2 isoform 1 (human)

hKCND2/iso:1


"An A-type voltage-gated potassium channel KCND2 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-sequence



PR:Q9Z0V2-1

A-type voltage-gated potassium channel KCND2 isoform 1 (mouse)

mKCND2/iso:1


"An A-type voltage-gated potassium channel KCND2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-modification



PR:000036577

A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 1 (mouse)

mKCND2/iso:1/Phos:1


"An A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q9Z0V2-1, Thr-38, MOD:00047|Ser-552, MOD:00046." [PMID:10681507, PRO:CNA]


organism-modification



PR:000036578

A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 2 (mouse)

mKCND2/iso:1/Phos:2


"An A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 2 in mouse. UniProtKB:Q9Z0V2-1, Thr-38, MOD:00047." [PMID:11040264, PRO:CNA]

Yes

organism-modification



PR:000036579

A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 3 (mouse)

mKCND2/iso:1/Phos:3


"An A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 3 in mouse. UniProtKB:Q9Z0V2-1, Ser-552, MOD:00046." [PMID:11040264, PRO:CNA]

Yes

organism-modification



PR:000036580

A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 4 (mouse)

mKCND2/iso:1/Phos:4


"An A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 4 in mouse. UniProtKB:Q9Z0V2-1, Thr-602/Thr-607, MOD:00047|Ser-616, MOD:00046." [PMID:11040264, PMID:16251476, PRO:CNA]

Yes

organism-modification



PR:000045389

A-type voltage-gated potassium channel KCND2 isoform 1 unphosphorylated 3 (mouse)

mKCND2/iso:1/UnPhos:3


"An A-type voltage-gated potassium channel KCND2 isoform 1 (mouse) that lacks phosphorylation on Ser-552. UniProtKB:Q9Z0V2-1, Ser-552, PR:000026291." [PMID:12829703, PRO:CNA]

Yes

organism-modification



PR:000045390

A-type voltage-gated potassium channel KCND2 isoform 1 unphosphorylated 4 (mouse)

mKCND2/iso:1/UnPhos:4


"An A-type voltage-gated potassium channel KCND2 isoform 1 (mouse) that lacks phosphorylation on Thr-602, Thr-607, and Ser-616. UniProtKB:Q9Z0V2-1, Thr-602/Thr-607/Ser-616, PR:000026291." [PMID:16251476, PRO:CNA]

Yes

modification



PR:000000988

A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated form

KCND2/iso:1/PhosRes+


"An A-type voltage-gated potassium channel KCND2 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000000994

A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 1

KCND2/iso:1/Phos:1


"An A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated form in which the phosphorylation occurs within the amino- and carboxyl-terminal cytoplasmic domains by cAMP-dependent protein kinase (PKA). At the N terminus, the phosporylation occurs at a Thr residue within the PKA consensus phosphorylation sequence adjacent to the first transmembrane domain (segment S1). At the C-terminus, it occurs at the conserved Ser within the motif [RQ]GS[IV]QEL. Example: UniProtKB:Q9Z0V2-1, Thr-38, MOD:00047|Ser-552, MOD:00046." [PMID:10681507]


organism-modification



PR:000036577

A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 1 (mouse)

mKCND2/iso:1/Phos:1


"An A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q9Z0V2-1, Thr-38, MOD:00047|Ser-552, MOD:00046." [PMID:10681507, PRO:CNA]


modification



PR:000000995

A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 2

KCND2/iso:1/Phos:2


"An A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated form in which the phosphorylation occurs within the amino-terminal cytoplasmic domain by cAMP-dependent protein kinase (PKA). The phosporylation occurs at a Thr residue within the PKA consensus phosphorylation sequence adjacent to the first transmembrane domain (segment S1). Example: UniProtKB:Q9Z0V2-1, Thr-38, MOD:00047." [PMID:11040264]


organism-modification



PR:000036578

A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 2 (mouse)

mKCND2/iso:1/Phos:2


"An A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 2 in mouse. UniProtKB:Q9Z0V2-1, Thr-38, MOD:00047." [PMID:11040264, PRO:CNA]

Yes

modification



PR:000000996

A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 3

KCND2/iso:1/Phos:3


"An A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated form in which the phosphorylation occurs within the carboxyl-terminal cytoplasmic domain by cAMP-dependent protein kinase (PKA). Phosphorylation occurs at the conserved Ser within the motif [RQ]GS[IV]QEL. Example: UniProtKB:Q9Z0V2-1, Ser-552, MOD:00046." [PRO:CNA]


organism-modification



PR:000036579

A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 3 (mouse)

mKCND2/iso:1/Phos:3


"An A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 3 in mouse. UniProtKB:Q9Z0V2-1, Ser-552, MOD:00046." [PMID:11040264, PRO:CNA]

Yes

modification



PR:000000997

A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 4

KCND2/iso:1/Phos:4


"An A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated form in which the phosphorylation occurs within the carboxyl-terminal cytoplasmic domain by ERK at the three most C-terminal consensus motifs (minimal motif=a Ser or Thr followed directly by a proline). Example: UniProtKB:Q9Z0V2-1, Thr-602/Thr-607, MOD:00047|Ser-616, MOD:00046." [PMID:11080179]


organism-modification



PR:000036580

A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 4 (mouse)

mKCND2/iso:1/Phos:4


"An A-type voltage-gated potassium channel KCND2 isoform 1 phosphorylated 4 in mouse. UniProtKB:Q9Z0V2-1, Thr-602/Thr-607, MOD:00047|Ser-616, MOD:00046." [PMID:11040264, PMID:16251476, PRO:CNA]

Yes

gene



PR:000000786

voltage-gated potassium channel KCND3

KCND3


"A shal-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCND3 gene or a 1:1 ortholog thereof. These subunits form homotetramers or heterotetramers with KCND1 and/or KCND2. Associates with the regulatory subunits KCNIP1, KCNIP2, KCNIP3 and KCNIP4." [PRO:CNA]


organism-gene



PR:Q62897

A-type voltage-gated potassium channel KCND3 (rat)

rKCND3


"A voltage-gated potassium channel KCND3 that is encoded in the genome of rat." [OMA:Q62897, PRO:DNx]


organism-sequence



PR:Q62897-1

A-type voltage-gated potassium channel KCND3 isoform r1 (rat)

rKCND3/iso:r1


"An A-type voltage-gated potassium channel KCND3 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62897-1." [PRO:DNx, UniProtKB:Q62897]


organism-sequence



PR:Q62897-2

A-type voltage-gated potassium channel KCND3 isoform r2 (rat)

rKCND3/iso:r2


"An A-type voltage-gated potassium channel KCND3 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62897-2." [PRO:DNx, UniProtKB:Q62897]


organism-sequence



PR:Q62897-3

A-type voltage-gated potassium channel KCND3 isoform r3 (rat)

rKCND3/iso:r3


"An A-type voltage-gated potassium channel KCND3 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62897-3." [PRO:DNx, UniProtKB:Q62897]


organism-gene



PR:Q9UK17

A-type voltage-gated potassium channel KCND3 (human)

hKCND3


"A voltage-gated potassium channel KCND3 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9UK17]


organism-sequence



PR:Q9UK17-1

A-type voltage-gated potassium channel KCND3 isoform 1 (human)

hKCND3/iso:1


"A voltage-gated potassium channel KCND3 isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UK17]

Yes

organism-sequence



PR:Q9UK17-2

A-type voltage-gated potassium channel KCND3 isoform 2 (human)

hKCND3/iso:2


"A voltage-gated potassium channel KCND3 isoform 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UK17]

Yes

organism-gene



PR:Q9Z0V1

A-type voltage-gated potassium channel KCND3 (mouse)

mKCND3


"A voltage-gated potassium channel KCND3 that is encoded in the genome of mouse." [OMA:Q9Z0V1, PRO:DNx]


organism-sequence



PR:Q9Z0V1-1

potassium voltage-gated channel subfamily D member 3 isoform 1 (mouse)

mKCND3/iso:1


"A voltage-gated potassium channel KCND3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:Q9Z0V1]


organism-sequence



PR:Q9Z0V1-2

potassium voltage-gated channel subfamily D member 3 isoform 2 (mouse)

mKCND3/iso:2


"A voltage-gated potassium channel KCND3 isoform 2 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:Q9Z0V1]


organism-sequence



PR:Q9Z0V1-3

A-type voltage-gated potassium channel KCND3 isoform m3 (mouse)

mKCND3/iso:m3


"An A-type voltage-gated potassium channel KCND3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z0V1-3." [PRO:DNx, UniProtKB:Q9Z0V1]


sequence



PR:000000948

voltage-gated potassium channel KCND3 isoform 1

KCND3/iso:1


"A voltage-gated potassium channel KCND3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UK17-1 or a 1:1 ortholog thereof." [PMID:9843794, PRO:CNA, PRO:DAN]


organism-sequence



PR:Q9UK17-1

A-type voltage-gated potassium channel KCND3 isoform 1 (human)

hKCND3/iso:1


"A voltage-gated potassium channel KCND3 isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UK17]

Yes

organism-sequence



PR:Q9Z0V1-1

potassium voltage-gated channel subfamily D member 3 isoform 1 (mouse)

mKCND3/iso:1


"A voltage-gated potassium channel KCND3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:Q9Z0V1]


sequence



PR:000000949

voltage-gated potassium channel KCND3 isoform 2

KCND3/iso:2


"A voltage-gated potassium channel KCND3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UK17-2 or a 1:1 ortholog thereof." [PMID:9843794, PRO:CNA, PRO:DAN]


organism-sequence



PR:Q9UK17-2

A-type voltage-gated potassium channel KCND3 isoform 2 (human)

hKCND3/iso:2


"A voltage-gated potassium channel KCND3 isoform 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UK17]

Yes

organism-sequence



PR:Q9Z0V1-2

potassium voltage-gated channel subfamily D member 3 isoform 2 (mouse)

mKCND3/iso:2


"A voltage-gated potassium channel KCND3 isoform 2 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:Q9Z0V1]


family



PR:000000711

shaw-related voltage-gated potassium channel alpha subunit

fam:Kchan_shaw_sub-a


"A voltage-gated potassium channel alpha subunit that is a constituent of Kv3 channels. These proteins are characterized by the high sequence conservation in the S5 segment which seems to determine the gating properties of the Kv3 channels: rightward shifted voltage dependence and fast deactivation rates. They also contain an ATM motif at the lysine-rich C-terminal region that is unique to this group. Kv3 channels are necessary for high-frequency, repetitive firing of action potentials. High activation threshold is a hallmark of Kv3 channels. They regulate rapid spiking, transmitter release and dendritic integration of many central neurons. In common with Kv2 and Kv4 channels, the tetramerization domain at the N terminus contains a zinc-binding site." [PMID:11506885]


gene



PR:000000781

voltage-gated potassium channel KCNC1

KCNC1


"A shaw-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNC1 gene or a 1:1 ortholog thereof. They contain an ATM motif at the C-terminus, following the S6 segment that allows interaction with axonal targeting machinery when exposed." [PRO:CNA]


organism-gene



PR:P15388

voltage-gated potassium channel KCNC1 (mouse)

mKCNC1


"A voltage-gated potassium channel KCNC1 that is encoded in the genome of mouse." [OMA:P15388, PRO:DNx]


organism-sequence



PR:P15388-1

voltage-gated potassium channel KCNC1, isoform Short (mouse)

mKCNC1/iso:Short


"A voltage-gated potassium channel KCNC1 isoform Short that is encoded in the genome of mouse." [PMID:2599109, PRO:HJD]


organism-sequence



PR:P15388-3

voltage-gated potassium channel KCNC1, isoform Long (mouse)

mKCNC1/iso:Long


"A voltage-gated potassium channel KCNC1 isoform Long that is encoded in the genome of mouse." [PMID:2599109, PRO:HJD, RefSeq:NP_001106210]


organism-gene



PR:P25122

voltage-gated potassium channel KCNC1 (rat)

rKCNC1


"A voltage-gated potassium channel KCNC1 that is encoded in the genome of rat." [OMA:P25122, PRO:DNx]


organism-sequence



PR:P25122-1

voltage-gated potassium channel KCNC1 isoform Long (rat)

rKCNC1/iso:Long


"A voltage-gated potassium channel KCNC1 isoform Long that is encoded in the genome of rat." [PRO:CNA]

Yes

organism-modification



PR:000036575

voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 (rat)

rKCNC1/iso:Long/Phos:1


"A voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 in rat. UniProtKB:P25122-1, Ser-503, MOD:00046." [PMID:16595659, PRO:CNA]

Yes

organism-modification



PR:000045386

voltage-gated potassium channel KCNC1 isoform Long unphosphorylated 1 (rat)

rKCNC1/iso:Long/UnPhos:1


"A voltage-gated potassium channel KCNC1 isoform Long (rat) that lacks phosphorylation on Ser-503. UniProtKB:P25122-1, Ser-503, PR:000026291." [PMID:16595659, PRO:CNA]

Yes

organism-sequence



PR:P25122-2

voltage-gated potassium channel KCNC1 isoform Short (rat)

rKCNC1/iso:Short


"A voltage-gated potassium channel KCNC1 isoform Short that is encoded in the genome of rat." [PRO:CNA]

Yes

organism-gene



PR:P48547

voltage-gated potassium channel KCNC1 (human)

hKCNC1


"A voltage-gated potassium channel KCNC1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P48547]


organism-sequence



PR:P48547-1

voltage-gated potassium channel KCNC1 isoform 1 (human)

hKCNC1/iso:1


"A voltage-gated potassium channel KCNC1 isoform Short that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:P48547-2

voltage-gated potassium channel KCNC1 isoform h2 (human)

hKCNC1/iso:h2


"A voltage-gated potassium channel KCNC1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48547-2." [PRO:DNx, UniProtKB:P48547]


sequence



PR:000000939

voltage-gated potassium channel KCNC1 isoform Short

KCNC1/iso:Short


"A voltage-gated potassium channel KCNC1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48547-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P15388-1

voltage-gated potassium channel KCNC1, isoform Short (mouse)

mKCNC1/iso:Short


"A voltage-gated potassium channel KCNC1 isoform Short that is encoded in the genome of mouse." [PMID:2599109, PRO:HJD]


organism-sequence



PR:P25122-2

voltage-gated potassium channel KCNC1 isoform Short (rat)

rKCNC1/iso:Short


"A voltage-gated potassium channel KCNC1 isoform Short that is encoded in the genome of rat." [PRO:CNA]

Yes

organism-sequence



PR:P48547-1

voltage-gated potassium channel KCNC1 isoform 1 (human)

hKCNC1/iso:1


"A voltage-gated potassium channel KCNC1 isoform Short that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000000940

voltage-gated potassium channel KCNC1 isoform Long

KCNC1/iso:Long


"A voltage-gated potassium channel KCNC1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P25122-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P15388-3

voltage-gated potassium channel KCNC1, isoform Long (mouse)

mKCNC1/iso:Long


"A voltage-gated potassium channel KCNC1 isoform Long that is encoded in the genome of mouse." [PMID:2599109, PRO:HJD, RefSeq:NP_001106210]


organism-sequence



PR:P25122-1

voltage-gated potassium channel KCNC1 isoform Long (rat)

rKCNC1/iso:Long


"A voltage-gated potassium channel KCNC1 isoform Long that is encoded in the genome of rat." [PRO:CNA]

Yes

organism-modification



PR:000036575

voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 (rat)

rKCNC1/iso:Long/Phos:1


"A voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 in rat. UniProtKB:P25122-1, Ser-503, MOD:00046." [PMID:16595659, PRO:CNA]

Yes

organism-modification



PR:000045386

voltage-gated potassium channel KCNC1 isoform Long unphosphorylated 1 (rat)

rKCNC1/iso:Long/UnPhos:1


"A voltage-gated potassium channel KCNC1 isoform Long (rat) that lacks phosphorylation on Ser-503. UniProtKB:P25122-1, Ser-503, PR:000026291." [PMID:16595659, PRO:CNA]

Yes

modification



PR:000000986

voltage-gated potassium channel KCNC1 isoform Long phosphorylated form

KCNC1/iso:Long/PhosRes+


"A voltage-gated potassium channel KCNC1 isoform Long that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000000992

voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1

KCNC1/iso:Long/Phos:1


"A voltage-gated potassium channel KCNC1 isoform Long phosphorylated form in which the phosphorylation occurs by the action of PKC at the Ser residue within the DSKL motif located in the C-terminal tail. In resting neurons, basal phosphorylation at this site decreases Kv3.1 channel current, reducing neuronal ability to follow high frequency stimulation. Example: UniProtKB:P25122-1, Ser-503, MOD:00046." [PMID:16595659]


organism-modification



PR:000036575

voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 (rat)

rKCNC1/iso:Long/Phos:1


"A voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 in rat. UniProtKB:P25122-1, Ser-503, MOD:00046." [PMID:16595659, PRO:CNA]

Yes

gene



PR:000000782

voltage-gated potassium channel KCNC2

KCNC2


"A shaw-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNC2 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P22462

voltage-gated potassium channel KCNC2 (rat)

rKCNC2


"A voltage-gated potassium channel KCNC2 that is encoded in the genome of rat." [OMA:P22462, PRO:DNx]


organism-sequence



PR:P22462-1

potassium voltage-gated channel subfamily C member 2 isoform KV3.2B (rat)

rKCNC2/iso:KV3.2B


"A voltage-gated potassium channel KCNC2 isoform 1 that is encoded in the genome of rat." [PRO:DNx, UniProtKB:P22462]

Yes

organism-sequence



PR:P22462-2

voltage-gated potassium channel KCNC2 isoform r2 (rat)

rKCNC2/iso:r2


"A voltage-gated potassium channel KCNC2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22462-2." [PRO:DNx, UniProtKB:P22462]


organism-sequence



PR:P22462-3

potassium voltage-gated channel subfamily C member 2 isoform KSHIIIA.1 (rat)

rKCNC2/iso:KSHIIIA.1


"A voltage-gated potassium channel KCNC2 isoform 3 that is encoded in the genome of rat." [PRO:CNA]

Yes

organism-sequence



PR:P22462-4

voltage-gated potassium channel KCNC2 isoform r4 (rat)

rKCNC2/iso:r4


"A voltage-gated potassium channel KCNC2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22462-4." [PRO:DNx, UniProtKB:P22462]


organism-gene



PR:Q14B80

voltage-gated potassium channel KCNC2 (mouse)

mKCNC2


"A voltage-gated potassium channel KCNC2 that is encoded in the genome of mouse." [OMA:Q14B80, PRO:DNx]


organism-gene



PR:Q96PR1

voltage-gated potassium channel KCNC2 (human)

hKCNC2


"A voltage-gated potassium channel KCNC2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q96PR1]


organism-sequence



PR:Q96PR1-1

voltage-gated potassium channel KCNC2 isoform 1 (human)

hKCNC2/iso:1


"A voltage-gated potassium channel KCNC2 isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96PR1]


organism-sequence



PR:Q96PR1-2

voltage-gated potassium channel KCNC2 isoform 2 (human)

hKCNC2/iso:2


"A voltage-gated potassium channel KCNC2 isoform 2 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q96PR1-3

voltage-gated potassium channel KCNC2 isoform 3 (human)

hKCNC2/iso:3


"A voltage-gated potassium channel KCNC2 isoform 3 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q96PR1-4

voltage-gated potassium channel KCNC2 isoform 4 (human)

hKCNC2/iso:4


"A voltage-gated potassium channel KCNC2 isoform 4 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q96PR1-5

voltage-gated potassium channel KCNC2 isoform h5 (human)

hKCNC2/iso:h5


"A voltage-gated potassium channel KCNC2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PR1-5." [PRO:DNx, UniProtKB:Q96PR1]


organism-sequence



PR:Q96PR1-6

voltage-gated potassium channel KCNC2 isoform h6 (human)

hKCNC2/iso:h6


"A voltage-gated potassium channel KCNC2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PR1-6." [PRO:DNx, UniProtKB:Q96PR1]


sequence



PR:000000941

voltage-gated potassium channel KCNC2 isoform 1

KCNC2/iso:1


"A voltage-gated potassium channel KCNC2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22462-1 or a 1:1 ortholog thereof." [PMID:1879548, PRO:CNA, PRO:DAN]


organism-sequence



PR:P22462-1

potassium voltage-gated channel subfamily C member 2 isoform KV3.2B (rat)

rKCNC2/iso:KV3.2B


"A voltage-gated potassium channel KCNC2 isoform 1 that is encoded in the genome of rat." [PRO:DNx, UniProtKB:P22462]

Yes

organism-sequence



PR:Q96PR1-1

voltage-gated potassium channel KCNC2 isoform 1 (human)

hKCNC2/iso:1


"A voltage-gated potassium channel KCNC2 isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96PR1]


sequence



PR:000000942

voltage-gated potassium channel KCNC2 isoform 2

KCNC2/iso:2


"A voltage-gated potassium channel KCNC2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PR1-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:Q96PR1-2

voltage-gated potassium channel KCNC2 isoform 2 (human)

hKCNC2/iso:2


"A voltage-gated potassium channel KCNC2 isoform 2 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000000943

voltage-gated potassium channel KCNC2 isoform 3

KCNC2/iso:3


"A voltage-gated potassium channel KCNC2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PR1-3 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P22462-3

potassium voltage-gated channel subfamily C member 2 isoform KSHIIIA.1 (rat)

rKCNC2/iso:KSHIIIA.1


"A voltage-gated potassium channel KCNC2 isoform 3 that is encoded in the genome of rat." [PRO:CNA]

Yes

organism-sequence



PR:Q96PR1-3

voltage-gated potassium channel KCNC2 isoform 3 (human)

hKCNC2/iso:3


"A voltage-gated potassium channel KCNC2 isoform 3 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000000944

voltage-gated potassium channel KCNC2 isoform 4

KCNC2/iso:4


"A voltage-gated potassium channel KCNC2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PR1-4 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:Q96PR1-4

voltage-gated potassium channel KCNC2 isoform 4 (human)

hKCNC2/iso:4


"A voltage-gated potassium channel KCNC2 isoform 4 that is encoded in the genome of human." [PRO:CNA]


gene



PR:000000783

voltage-gated potassium channel KCNC4

KCNC4


"A shaw-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNC4 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:E1C3U8

uncharacterized protein, KCNC4 translation product (chicken)

chick-KCNC4


"A voltage-gated potassium channel KCNC4 that is encoded in the genome of chicken." [OMA:E1C3U8, PRO:CNA]


organism-gene



PR:Q03721

voltage-gated potassium channel KCNC4 (human)

hKCNC4


"A voltage-gated potassium channel KCNC4 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q03721]


organism-sequence



PR:Q03721-1

voltage-gated potassium channel KCNC4 isoform 1 (human)

hKCNC4/iso:1


"A voltage-gated potassium channel KCNC4 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q03721-2

voltage-gated potassium channel KCNC4 isoform 2 (human)

hKCNC4/iso:2


"A voltage-gated potassium channel KCNC4 isoform 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q03721]


organism-modification



PR:000036576

voltage-gated potassium channel KCNC4 isoform 2 phosphorylated 1 (human)

hKCNC4/iso:2/Phos:1


"A voltage-gated potassium channel KCNC4 isoform 2 phosphorylated 1 in human. UniProtKB:Q03721-2, Ser-8/Ser-9/Ser-15/Ser-21, MOD:00046." [PMID:7993631, PMID:9649584, PRO:CNA]

Yes

organism-modification



PR:000045387

voltage-gated potassium channel KCNC4 isoform 2 unphosphorylated 1 (human)

hKCNC4/iso:2/UnPhos:1


"A voltage-gated potassium channel KCNC4 isoform 2 (human) that lacks phosphorylation on Ser-8, Ser-9, Ser-15 and Ser-21. UniProtKB:Q03721-2, Ser-8/Ser-9/Ser-15/Ser-21, PR:000026291." [PMID:7993631, PMID:9649584, PRO:CNA]

Yes

organism-sequence



PR:Q03721-3

voltage-gated potassium channel KCNC4 isoform h3 (human)

hKCNC4/iso:h3


"A voltage-gated potassium channel KCNC4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03721-3." [PRO:DNx, UniProtKB:Q03721]


organism-gene



PR:Q63734

voltage-gated potassium channel KCNC4 (rat)

rKCNC4


"A voltage-gated potassium channel KCNC4 that is encoded in the genome of rat." [OMA:Q63734, PRO:DNx]


organism-gene



PR:Q8R1C0

voltage-gated potassium channel KCNC4 (mouse)

mKCNC4


"A voltage-gated potassium channel KCNC4 that is encoded in the genome of mouse." [OMA:Q8R1C0, PRO:DNx]


sequence



PR:000000945

voltage-gated potassium channel KCNC4 isoform 1

KCNC4/iso:1


"A voltage-gated potassium channel KCNC4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03721-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:Q03721-1

voltage-gated potassium channel KCNC4 isoform 1 (human)

hKCNC4/iso:1


"A voltage-gated potassium channel KCNC4 isoform 1 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000000946

voltage-gated potassium channel KCNC4 isoform 2

KCNC4/iso:2


"A voltage-gated potassium channel KCNC4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03721-2 or a 1:1 ortholog thereof." [PMID:1381835, PRO:CNA, PRO:DAN]


organism-sequence



PR:Q03721-2

voltage-gated potassium channel KCNC4 isoform 2 (human)

hKCNC4/iso:2


"A voltage-gated potassium channel KCNC4 isoform 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q03721]


organism-modification



PR:000036576

voltage-gated potassium channel KCNC4 isoform 2 phosphorylated 1 (human)

hKCNC4/iso:2/Phos:1


"A voltage-gated potassium channel KCNC4 isoform 2 phosphorylated 1 in human. UniProtKB:Q03721-2, Ser-8/Ser-9/Ser-15/Ser-21, MOD:00046." [PMID:7993631, PMID:9649584, PRO:CNA]

Yes

organism-modification



PR:000045387

voltage-gated potassium channel KCNC4 isoform 2 unphosphorylated 1 (human)

hKCNC4/iso:2/UnPhos:1


"A voltage-gated potassium channel KCNC4 isoform 2 (human) that lacks phosphorylation on Ser-8, Ser-9, Ser-15 and Ser-21. UniProtKB:Q03721-2, Ser-8/Ser-9/Ser-15/Ser-21, PR:000026291." [PMID:7993631, PMID:9649584, PRO:CNA]

Yes

modification



PR:000000987

voltage-gated potassium channel KCNC4 isoform 2 phosphorylated form

KCNC4/iso:2/PhosRes+


"A voltage-gated potassium channel KCNC4 isoform 2 that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000000993

voltage-gated potassium channel KCNC4 isoform 2 phosphorylated 1

KCNC4/iso:2/Phos:1


"A voltage-gated potassium channel KCNC4 isoform 2 phosphorylated form in which the phosphorylation occurs by the action of PKC at multiple Ser residues located in the N-terminal domain. Example: UniProtKB:Q03721-2, Ser-8/Ser-9/Ser-15/Ser-21, MOD:00046." [PRO:CNA]


organism-modification



PR:000036576

voltage-gated potassium channel KCNC4 isoform 2 phosphorylated 1 (human)

hKCNC4/iso:2/Phos:1


"A voltage-gated potassium channel KCNC4 isoform 2 phosphorylated 1 in human. UniProtKB:Q03721-2, Ser-8/Ser-9/Ser-15/Ser-21, MOD:00046." [PMID:7993631, PMID:9649584, PRO:CNA]

Yes

modification



PR:000002655

voltage-gated potassium channel KCNC4 isoform 2 unmodified form

KCNC4/iso:2/UnMod


"A voltage-gated potassium channel KCNC4 isoform 2 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]


gene



PR:000009254

voltage-gated potassium channel KCNC3

KCNC3


"A shaw-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNC3 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q01956

voltage-gated potassium channel KCNC3 (rat)

rKCNC3


"A voltage-gated potassium channel KCNC3 that is encoded in the genome of rat." [OMA:Q01956, PRO:DNx]


organism-sequence



PR:Q01956-1

voltage-gated potassium channel KCNC3 isoform rKSHIIID.1 (rat)

rKCNC3/iso:rKSHIIID.1


"A voltage-gated potassium channel KCNC3 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01956-1." [PRO:DNx, UniProtKB:Q01956]


organism-sequence



PR:Q01956-2

voltage-gated potassium channel KCNC3 isoform rKSHIIID.2 (rat)

rKCNC3/iso:rKSHIIID.2


"A voltage-gated potassium channel KCNC3 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01956-2." [PRO:DNx, UniProtKB:Q01956]


organism-gene



PR:Q14003

voltage-gated potassium channel KCNC3 (human)

hKCNC3


"A voltage-gated potassium channel KCNC3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q14003]


organism-gene



PR:Q63959

voltage-gated potassium channel KCNC3 (mouse)

mKCNC3


"A voltage-gated potassium channel KCNC3 that is encoded in the genome of mouse." [OMA:Q63959, PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000000685 fam:Kchan_sub-a
This pore is formed by these subunits that encircle a central ion conduction pathway
enablescontributes_to GO:0005249 voltage-gated potassium channel activity PIRSF:PIRSF002449
located_inGO:0008076 voltage-gated potassium channel complex PIRSF:PIRSF002449
PR:000000701 fam:Kchan_sub-KCNG
The alteration of the PxP motif seems to be an important determinant of the regulatory function of modulatory subunits
enablesGO:0015459 potassium channel regulator activity PIRSF:PIRSF500980
PR:000000702 fam:Kchan_sub-KCNS
The alteration of the PxP motif seems to be an important determinant of the regulatory function of modulatory subunits
enablesGO:0015459 potassium channel regulator activity PIRSF:PIRSF500981
PR:000000724 KCNF1
Unlike other potassium channel subunits, KCNF1 subunits are not able to form functional channels on their own
enablescontributes_to GO:0005251 delayed rectifier potassium channel activity PMID:9696692
GO:0015459 potassium channel regulator activity PMID:9696692
located_inGO:0008076 voltage-gated potassium channel complex PMID:9696692
PR:000000725 KCNV1
It modulates the activity of KCNB1 and KCNB2 channels by changing kinetics and levels of expression and by shifting the half-inactivation potential to more polarized values
enablesGO:0015459 potassium channel regulator activity PANTHER:PTHR11537
PR:000000726 KCNV2
The alteration of the PxP motif seems to be an important determinant of the regulatory function of modulatory subunits
enablesGO:0015459 potassium channel regulator activity PANTHER:PTHR11537
PR:000000803 hKCNV2/var:G459D
UniProtKB:Q8TDN2, Gly-459, CHEBI:29958
associated_with_disease_progressionDO:0050795 cone dystrophy PMID:16909397
PR:000000804 hKCNV2/var:A259V
UniProtKB:Q8TDN2, Ala-259, CHEBI:30015
associated_with_disease_progressionDO:0050795 cone dystrophy PMID:16909397
PR:000000805 hKCNV2/var:L126Q
UniProtKB:Q8TDN2, Leu-126, CHEBI:30011
associated_with_disease_progressionDO:0050795 cone dystrophy PMID:16909397
PR:000000806 hKCNV2/var:4
UniProtKB:Q8TDN2, 1-338, 342-545
associated_with_disease_progressionDO:0050795 cone dystrophy PMID:16909397
PR:000000807 hKCNV2/var:S256W
UniProtKB:Q8TDN2, Ser-256, CHEBI:29954
associated_with_disease_progressionDO:0050795 cone dystrophy PMID:16909397
PR:000000808 hKCNV2/var:W188C
UniProtKB:Q8TDN2, Trp-188, CHEBI:29950
associated_with_disease_progressionDO:0050795 cone dystrophy PMID:16909397
PR:000002684 KCNA5/iso:2/UnMod located_inGO:0005886 plasma membrane MGI_ref:63618; PMID:8226976
PR:000036568 hKCNA5/iso:1/var:E375*
UniProtKB:P22460-1, 1-374
enablesNOT|contributes_to GO:0005251 delayed rectifier potassium channel activity PMID:16772329
PR:000036575 rKCNC1/iso:Long/Phos:1
UniProtKB:P25122-1, Ser-503, MOD:00046
enablesdecreased|contributes_to GO:0005249 voltage-gated potassium channel activity relative to PR:000002649 PMID:16595659
located_inGO:0016020 membrane PMID:16595659
PR:000036576 hKCNC4/iso:2/Phos:1
UniProtKB:Q03721-2, Ser-8/Ser-9/Ser-15/Ser-21, MOD:00046
enablesdecreased|contributes_to GO:0005250 A-type (transient outward) potassium channel activity relative to PR:000002655 KCNC4/iso:2/UnMod PMID:7993631; PMID:9649584
PR:000036578 mKCND2/iso:1/Phos:2
UniProtKB:Q9Z0V2-1, Thr-38, MOD:00047
located_inGO:0030425 dendrite PMID:11040264
PR:000036579 mKCND2/iso:1/Phos:3
UniProtKB:Q9Z0V2-1, Ser-552, MOD:00046
located_inGO:0030425 dendrite PMID:11040264
PR:000036580 mKCND2/iso:1/Phos:4
UniProtKB:Q9Z0V2-1, Thr-602/Thr-607, MOD:00047|Ser-616, MOD:00046
enablesdecreased|contributes_to GO:0005250 A-type (transient outward) potassium channel activity relative to PR:000002656 PMID:16251476
located_inGO:0009986 cell surface PMID:16251476
GO:0030425 dendrite PMID:11040264
PR:000036584 hKCNA2/iso:1/Phos:1
UniProtKB:P16389-1, Tyr-132, MOD:00048
enablesNOT GO:0005251 delayed rectifier potassium channel activity PMID:15215309
located_inGO:0005768 endosome PMID:15215309
PR:000036585 mKCNA2/iso:1/Phos:2
UniProtKB:P63141-1, Ser-440/Ser-441, MOD:00046
located_inGO:0008076 voltage-gated potassium channel complex PMID:18056633
GO:0009986 cell surface PMID:18056633
PR:000036586 rKCNA2/iso:1/Phos:2
UniProtKB:P63142-1, Ser-440/Ser-441, MOD:00046
located_inGO:0008076 voltage-gated potassium channel complex PMID:18056633
GO:0009986 cell surface PMID:18056633
PR:000036587 hKCNA2/iso:1/Phos:2
UniProtKB:P16389-1, Ser-440/Ser-441, MOD:00046
located_inGO:0008076 voltage-gated potassium channel complex PMID:18056633
GO:0009986 cell surface PMID:18056633
PR:000036639 hKCNA3/iso:1/Phos:1 enablesdecreased GO:0015271 outward rectifier potassium channel activity relative to PR:000002682 KCNA3/iso:1/UnMod PMID:9989602
PR:000044513 mKCNA4/iso:1/Phos:1
UniProtKB:Q61423-1, Ser-122, MOD:00046
located_inGO:0014069 postsynaptic density PMID:18056256
PR:000044708 hKCNA3/iso:1/UnMod enablesGO:0015271 outward rectifier potassium channel activity PMID:9989602
PR:000045386 rKCNC1/iso:Long/UnPhos:1
UniProtKB:P25122-1, Ser-503, PR:000026291
enablescontributes_to GO:0005249 voltage-gated potassium channel activity PMID:16595659
PR:000045387 hKCNC4/iso:2/UnPhos:1
UniProtKB:Q03721-2, Ser-8/Ser-9/Ser-15/Ser-21, PR:000026291
enablescontributes_to GO:0005250 A-type (transient outward) potassium channel activity PMID:1381835; PMID:7993631; PMID:9649584
PR:000045389 mKCND2/iso:1/UnPhos:3
UniProtKB:Q9Z0V2-1, Ser-552, PR:000026291
located_inGO:0009986 cell surface PMID:12829703; PMID:16251476
PR:000045390 mKCND2/iso:1/UnPhos:4
UniProtKB:Q9Z0V2-1, Thr-602/Thr-607/Ser-616, PR:000026291
enablescontributes_to GO:0005250 A-type (transient outward) potassium channel activity PMID:16251476
PR:O35173-1 mKCNS1/iso:1 enablesGO:0015459 potassium channel regulator activity PMID:9305895
PR:O35174-1 mKCNS2/iso:1 enablesGO:0015459 potassium channel regulator activity PMID:9305895
PR:P16389-1 hKCNA2/iso:1 enablescontributes_to GO:0005251 delayed rectifier potassium channel activity PMID:1715584
located_inGO:0008076 voltage-gated potassium channel complex PMID:2251283
GO:0009986 cell surface PMID:15215309
PR:P22001-1 hKCNA3/iso:1 enablesGO:0005251 delayed rectifier potassium channel activity PMID:1986382
located_inGO:0005743 mitochondrial inner membrane PMID:15632141
GO:0005886 plasma membrane PMID:15632141
PR:P22460-1 hKCNA5/iso:1 enablescontributes_to GO:0005251 delayed rectifier potassium channel activity PMID:1986382
PR:P22462-1 rKCNC2/iso:KV3.2B enablescontributes_to GO:0015271 outward rectifier potassium channel activity PMID:1879548
PR:P22462-3 rKCNC2/iso:KSHIIIA.1 enablescontributes_to GO:0005249 voltage-gated potassium channel activity PMID:10414303; PMID:11506885
PR:P25122-1 rKCNC1/iso:Long enablesGO:0030506 ankyrin binding with PR:O70511 ANK-3 (rat) PMID:18094255
located_inGO:0030424 axon PMID:18094255
PR:P25122-2 rKCNC1/iso:Short located_inGO:0032809 neuronal cell body membrane PMID:18094255
PR:P63142-1 rKCNA2/iso:1 enablesGO:0005515 protein binding with PR:P78352 DLG4 PMID:17959782
PR:Q16322-1 hKCNA10/iso:1 enablescontributes_to GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity PMID:10836990; PMID:9177773
contributes_to GO:0005251 delayed rectifier potassium channel activity PMID:10836990
located_inGO:0008076 voltage-gated potassium channel complex PMID:12060596
PR:Q17ST2-1 mKCNA7/iso:1 enablesGO:0005249 voltage-gated potassium channel activity PMID:16801386
located_inGO:0008076 voltage-gated potassium channel complex PMID:16801386
PR:Q17ST2-2 mKCNA7/iso:2 enablesGO:0005249 voltage-gated potassium channel activity PMID:16801386
located_inGO:0008076 voltage-gated potassium channel complex PMID:16801386
PR:Q61762-1 mKCNA5/iso:1 acts_upstream_of_or_withinGO:0006813 potassium ion transport MGI_ref:63618; PMID:8226976
enablesGO:0005249 voltage-gated potassium channel activity MGI_ref:63618; PMID:8226976
located_inGO:0005886 plasma membrane MGI_ref:63618; PMID:8226976
PR:Q61762-2 mKCNA5/iso:2 acts_upstream_of_or_withinGO:0006813 potassium ion transport MGI_ref:63618; PMID:8226976
enablesGO:0005249 voltage-gated potassium channel activity MGI_ref:63618; PMID:8226976
located_inGO:0005886 plasma membrane MGI_ref:63618; PMID:8226976
PR:Q61762-3 mKCNA5/iso:3 acts_upstream_of_or_withinGO:0043267 negative regulation of potassium ion transport MGI_ref:63618; PMID:8226976
enablesGO:0019870 potassium channel inhibitor activity MGI_ref:63618; PMID:8226976
PR:Q8R523-1 rKCNG3/iso:1 acts_upstream_of_or_withinGO:0006813 potassium ion transport PMID:15046870
enablescontributes_to GO:0005249 voltage-gated potassium channel activity PMID:15046870
PR:Q8R523-2 rKCNG3/iso:2 acts_upstream_of_or_withinGO:0006813 potassium ion transport PMID:15046870
enablesGO:0005249 voltage-gated potassium channel activity PMID:15046870
PR:Q8TAE7-1 hKCNG3/iso:1 located_inGO:0005783 endoplasmic reticulum PMID:12060745
GO:0005886 plasma membrane PMID:12060745
PR:Q96KK3-1 hKCNS1/iso:1 enablescontributes_to GO:0005251 delayed rectifier potassium channel activity PMID:10484328
GO:0015459 potassium channel regulator activity PMID:10484328
located_inGO:0005886 plasma membrane PMID:10484328
PR:Q9NZV8-1 hKCND2/iso:1 acts_upstream_of_or_withinGO:0001508 action potential PMID:11102480
GO:0007268 chemical synaptic transmission PMID:11102480
located_inGO:0009986 cell surface PMID:12493773
PR:Q9UK17-1 hKCND3/iso:1 enablescontributes_to GO:0005250 A-type (transient outward) potassium channel activity PMID:8734615; PMID:9843794
PR:Q9UK17-2 hKCND3/iso:2 enablescontributes_to GO:0005250 A-type (transient outward) potassium channel activity PMID:9843794
PR:Q9Z0V2-1 mKCND2/iso:1 located_inGO:0005783 endoplasmic reticulum PMID:12829703