|
|
 |
 |
|  |  |
 |  |  |  |  |  |  |  |
gene
 |


|
 PR:000000686 |
   cyclic nucleotide-gated channel alpha-1
 |
   CNGA1
 |
  "A cyclic nucleotide-gated channel alpha subunit that is a translation product of the human CNGA1 gene or a 1:1 ortholog thereof. In the retina, these proteins can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |
 |  |  |  |  |  |
organism-gene
 |


|
 PR:P29973 |
   cyclic nucleotide-gated channel alpha-1 (human)
 |
   hCNGA1
 |
  "A cyclic nucleotide-gated channel alpha-1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P29973]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
organism-sequence
 |


|
 PR:000000738 |
   cyclic nucleotide-gated channel alpha-1 sequence variant S320F (human)
 |
   hCNGA1/var:S320F
 |
  "A cyclic nucleotide-gated channel alpha-1 (human) that has a Phe residue at the position equivalent to Ser-320 of the amino acid sequence represented by UniProtKB:P29973-1. Example: UniProtKB:P29973-1, Ser-320, CHEBI:29997." [PRO:CNA, PRO:DAN]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
organism-sequence
 |


|
 PR:P29973-1 |
   cyclic nucleotide-gated channel alpha-1 isoform 1 (human)
 |
   hCNGA1/iso:1
 |
  "A cyclic nucleotide-gated channel alpha-1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
organism-modification
 |


|
 PR:000078527 |
   cyclic nucleotide-gated channel alpha-1 deaminated 1 (human)
 |
   hCNGA1/Deam:1
 |
  "A cyclic nucleotide-gated channel alpha-1 (human) that has been deaminated on the residue at the position equivalent to Asn-159 of the amino acid sequence represented by UniProtKB:P29973. UniProtKB:P29973, Asn-159, MOD:00684." [IEDB_epitope:1327288, PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |
 |  |  |  |  |  |
organism-gene
 |


|
 PR:P29974 |
   cyclic nucleotide-gated channel alpha-1 (mouse)
 |
   mCNGA1
 |
  "A cyclic nucleotide-gated channel alpha-1 that is encoded in the genome of mouse." [OMA:P29974, PRO:DNx]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
organism-sequence
 |


|
 PR:P29974-1 |
   cyclic nucleotide-gated channel alpha-1 isoform 1 (mouse)
 |
   mCNGA1/iso:1
 |
  "A cyclic nucleotide-gated channel alpha-1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |
 |  |  |  |  |  |
organism-gene
 |


|
 PR:Q00194 |
   cyclic nucleotide-gated channel alpha-1 (cow)
 |
   cow-CNGA1
 |
  "A cyclic nucleotide-gated channel alpha-1 that is encoded in the genome of cow." [OMA:Q00194, PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
organism-sequence
 |


|
 PR:Q00194-1 |
   cyclic nucleotide-gated channel alpha-1 isoform 1 (cow)
 |
   cow-CNGA1/iso:1
 |
  "A cyclic nucleotide-gated channel alpha-1 isoform 1 that is encoded in the genome of cow." [PRO:CNA]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-modification
 |


|
 PR:000036569 |
   cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 1 (cow)
 |
   cow-CNGA1/iso:1/Phos:1
 |
  "A cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 1 in cow. UniProtKB:Q00194-1, Tyr-498, MOD:00048." [PMID:10366613, PMID:14602825, PRO:CNA]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-modification
 |


|
 PR:000045379 |
   cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 2 (cow)
 |
   cow-CNGA1/iso:1/Phos:2
 |
  "A cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 2 in cow. UniProtKB:Q00194-1, Tyr-498/Tyr-503, MOD:00048." [PMID:15381690, PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-modification
 |


|
 PR:000045381 |
   cyclic nucleotide-gated channel alpha-1 isoform 1 unphosphorylated 1 (cow)
 |
   cow-CNGA1/iso:1/UnPhos:1
 |
  "A cyclic nucleotide-gated channel alpha-1 isoform 1 (cow) that lacks phosphorylation on Tyr-498. UniProtKB:Q00194-1, Tyr-498, PR:000026291." [PMID:10366613, PRO:CNA]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |
 |  |  |  |  |  |
organism-gene
 |


|
 PR:Q62927 |
   cyclic nucleotide-gated channel alpha-1 (rat)
 |
   rCNGA1
 |
  "A cyclic nucleotide-gated channel alpha-1 that is encoded in the genome of rat." [OMA:Q62927, PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |
 |  |  |  |  |  |
organism-gene
 |


|
 PR:Q90980 |
   cyclic nucleotide-gated channel rod photoreceptor subunit alpha (chicken)
 |
   chick-CNGA1
 |
  "A cyclic nucleotide-gated channel alpha-1 that is encoded in the genome of chicken." [OMA:Q90980, PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |
 |  |  |  |  |  |
sequence
 |


|
 PR:000000737 |
   cyclic nucleotide-gated channel alpha-1 isoform 1
 |
   CNGA1/iso:1
 |
  "A cyclic nucleotide-gated channel alpha-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29973-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
organism-sequence
 |


|
 PR:P29973-1 |
   cyclic nucleotide-gated channel alpha-1 isoform 1 (human)
 |
   hCNGA1/iso:1
 |
  "A cyclic nucleotide-gated channel alpha-1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
organism-sequence
 |


|
 PR:P29974-1 |
   cyclic nucleotide-gated channel alpha-1 isoform 1 (mouse)
 |
   mCNGA1/iso:1
 |
  "A cyclic nucleotide-gated channel alpha-1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
organism-sequence
 |


|
 PR:Q00194-1 |
   cyclic nucleotide-gated channel alpha-1 isoform 1 (cow)
 |
   cow-CNGA1/iso:1
 |
  "A cyclic nucleotide-gated channel alpha-1 isoform 1 that is encoded in the genome of cow." [PRO:CNA]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-modification
 |


|
 PR:000036569 |
   cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 1 (cow)
 |
   cow-CNGA1/iso:1/Phos:1
 |
  "A cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 1 in cow. UniProtKB:Q00194-1, Tyr-498, MOD:00048." [PMID:10366613, PMID:14602825, PRO:CNA]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-modification
 |


|
 PR:000045379 |
   cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 2 (cow)
 |
   cow-CNGA1/iso:1/Phos:2
 |
  "A cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 2 in cow. UniProtKB:Q00194-1, Tyr-498/Tyr-503, MOD:00048." [PMID:15381690, PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-modification
 |


|
 PR:000045381 |
   cyclic nucleotide-gated channel alpha-1 isoform 1 unphosphorylated 1 (cow)
 |
   cow-CNGA1/iso:1/UnPhos:1
 |
  "A cyclic nucleotide-gated channel alpha-1 isoform 1 (cow) that lacks phosphorylation on Tyr-498. UniProtKB:Q00194-1, Tyr-498, PR:000026291." [PMID:10366613, PRO:CNA]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
modification
 |


|
 PR:000000932 |
   cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated form
 |
   CNGA1/iso:1/PhosRes+
 |
  "A cyclic nucleotide-gated channel alpha-1 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
modification
 |


|
 PR:000000981 |
   cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 1
 |
   CNGA1/iso:1/Phos:1
 |
  "A cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated form in which the phosphorylation occurs at the Tyr residue within the VYSPGD motif located at the N terminus of the cyclic-nucleotide binding domain (CNDB). Example: UniProtKB:Q00194-1, Tyr-498, MOD:00048." [PMID:10366613, PMID:14602825]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
organism-modification
 |


|
 PR:000036569 |
   cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 1 (cow)
 |
   cow-CNGA1/iso:1/Phos:1
 |
  "A cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 1 in cow. UniProtKB:Q00194-1, Tyr-498, MOD:00048." [PMID:10366613, PMID:14602825, PRO:CNA]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
modification
 |


|
 PR:000045378 |
   cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 2
 |
   CNGA1/iso:1/Phos:2
 |
  "A cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated form in which the phosphorylation occurs at the Tyr residue within the VYSPGD motif located at the N terminus of the cyclic-nucleotide binding domain (CNDB) and the residue at the position equivalent to Tyr-503 of the amino acid sequence represented by UniProtKB:Q00194-1. This phosphorylation prevents Ca2+/CaM inhibition of the CNG channel, but at the same time has a similar effect, that is decreases the apparent affinity for cGMP. Example: UniProtKB:Q00194-1, Tyr-498/Tyr-503, MOD:00048." [PMID:23032687, PRO:CNA, PRO:DAN]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
organism-modification
 |


|
 PR:000045379 |
   cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 2 (cow)
 |
   cow-CNGA1/iso:1/Phos:2
 |
  "A cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 2 in cow. UniProtKB:Q00194-1, Tyr-498/Tyr-503, MOD:00048." [PMID:15381690, PRO:CNA]
 |

| 
|
|
|