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Protein Ontology report - modulatory voltage-gated potassium channel subunit KCNG
PR:000000701 - http://purl.obolibrary.org/obo/PR_000000701
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000000701   
  PRO namemodulatory voltage-gated potassium channel subunit KCNG 
  Synonyms
PRO-Short-label: EXACT:fam:Kchan_sub-KCNG
Other: RELATED:silent subunit
  Definition"A voltage-gated potassium channel alpha subunit that is a modulator of the shab-related potassium channels (Kv2). Similarly to KCNF1, KCNV and KCNS subunits, KCNG subunits are not able to form functional channels on their own. Also in common with these modulatory subunits, it lacks the conserved PxP motif located in the distal part of S6. In this class the motif is PxT. The alteration of the PxP motif seems to be an important determinant of the regulatory function of modulatory subunits." [PMID:9305895] 
  PRO Categoryfamily 
  ParentPR:000000685 voltage-gated potassium channel alpha subunit
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene4                                                  Organism-Gene 11                                        
         Sequence5                                                  Organism-Sequence 10                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF500980
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000000701 modulatory voltage-gated potassium channel subunit KCNG
fam:Kchan_sub-KCNG
Yes
gene


PR:000000787 voltage-gated potassium channel KCNG1
KCNG1

organism-gene


PR:A2BDX4 voltage-gated potassium channel regulatory subunit KCNG1 (mouse)
mKCNG1

organism-gene


PR:D4AD53 voltage-gated potassium channel regulatory subunit KCNG1 (rat)
rKCNG1

organism-gene


PR:Q9UIX4 voltage-gated potassium channel regulatory subunit KCNG1 (human)
hKCNG1

organism-sequence


PR:Q9UIX4-1 voltage-gated potassium channel regulatory subunit KCNG1 isoform 1 (human)
hKCNG1/iso:1

organism-sequence


PR:Q9UIX4-2 voltage-gated potassium channel regulatory subunit KCNG1 isoform 2 (human)
hKCNG1/iso:2

sequence


PR:000000950 voltage-gated potassium channel KCNG1 isoform 1
KCNG1/iso:1

organism-sequence


PR:Q9UIX4-1 voltage-gated potassium channel regulatory subunit KCNG1 isoform 1 (human)
hKCNG1/iso:1

sequence


PR:000000951 voltage-gated potassium channel KCNG1 isoform 2
KCNG1/iso:2

organism-sequence


PR:Q9UIX4-2 voltage-gated potassium channel regulatory subunit KCNG1 isoform 2 (human)
hKCNG1/iso:2

gene


PR:000000788 voltage-gated potassium channel subfamily G member 3
KCNG3

organism-gene


PR:P59053 voltage-gated potassium channel regulatory subunit KCNG3 (mouse)
mKCNG3

organism-sequence


PR:P59053-1 voltage-gated potassium channel regulatory subunit KCNG3 isoform 1 (mouse)
mKCNG3/iso:1

organism-sequence


PR:P59053-2 voltage-gated potassium channel regulatory subunit KCNG3 isoform 2 (mouse)
mKCNG3/iso:2

organism-gene


PR:Q8R523 voltage-gated potassium channel regulatory subunit KCNG3 (rat)
rKCNG3

organism-sequence


PR:Q8R523-1 voltage-gated potassium channel regulatory subunit KCNG3 isoform 1 (rat)
rKCNG3/iso:1
Yes
organism-sequence


PR:Q8R523-2 voltage-gated potassium channel regulatory subunit KCNG3 isoform 2 (rat)
rKCNG3/iso:2
Yes
organism-gene


PR:Q8TAE7 voltage-gated potassium channel regulatory subunit KCNG3 (human)
hKCNG3

organism-sequence


PR:Q8TAE7-1 voltage-gated potassium channel regulatory subunit KCNG3 isoform 1 (human)
hKCNG3/iso:1
Yes
organism-sequence


PR:Q8TAE7-2 voltage-gated potassium channel regulatory subunit KCNG3 isoform 2 (human)
hKCNG3/iso:2

organism-modification


PR:000076129 voltage-gated potassium channel regulatory subunit KCNG3 phosphorylated 1 (human)
hKCNG3/Phos:1

sequence


PR:000000952 voltage-gated potassium channel subfamily G member 3 isoform 1
KCNG3/iso:1

organism-sequence


PR:P59053-1 voltage-gated potassium channel regulatory subunit KCNG3 isoform 1 (mouse)
mKCNG3/iso:1

organism-sequence


PR:Q8R523-1 voltage-gated potassium channel regulatory subunit KCNG3 isoform 1 (rat)
rKCNG3/iso:1
Yes
organism-sequence


PR:Q8TAE7-1 voltage-gated potassium channel regulatory subunit KCNG3 isoform 1 (human)
hKCNG3/iso:1
Yes
sequence


PR:000000953 voltage-gated potassium channel subfamily G member 3 isoform 2
KCNG3/iso:2

organism-sequence


PR:P59053-2 voltage-gated potassium channel regulatory subunit KCNG3 isoform 2 (mouse)
mKCNG3/iso:2

organism-sequence


PR:Q8R523-2 voltage-gated potassium channel regulatory subunit KCNG3 isoform 2 (rat)
rKCNG3/iso:2
Yes
organism-sequence


PR:Q8TAE7-2 voltage-gated potassium channel regulatory subunit KCNG3 isoform 2 (human)
hKCNG3/iso:2

gene


PR:000000789 voltage-gated potassium channel subfamily G member 4
KCNG4

organism-gene


PR:Q80XM3 voltage-gated potassium channel regulatory subunit KCNG4 (mouse)
mKCNG4

organism-gene


PR:Q8TDN1 voltage-gated potassium channel regulatory subunit KCNG4 (human)
hKCNG4

organism-sequence


PR:Q8TDN1-1 voltage-gated potassium channel regulatory subunit KCNG4 isoform 1 (human)
hKCNG4/iso:1

organism-sequence


PR:Q8TDN1-2 voltage-gated potassium channel regulatory subunit KCNG4 isoform h2 (human)
hKCNG4/iso:h2

sequence


PR:000000954 voltage-gated potassium channel subfamily G member 4 isoform 1
KCNG4/iso:1

organism-sequence


PR:Q8TDN1-1 voltage-gated potassium channel regulatory subunit KCNG4 isoform 1 (human)
hKCNG4/iso:1

gene


PR:000009259 voltage-gated potassium channel KCNG2
KCNG2

organism-gene


PR:O73606 voltage-gated potassium channel regulatory subunit KCNG2 (chicken)
chick-KCNG2

organism-gene


PR:Q9QYU3 voltage-gated potassium channel regulatory subunit KCNG2 (rat)
rKCNG2

organism-gene


PR:Q9UJ96 voltage-gated potassium channel regulatory subunit KCNG2 (human)
hKCNG2

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000000701 fam:Kchan_sub-KCNG
The alteration of the PxP motif seems to be an important determinant of the regulatory function of modulatory subunits		 enablesGO:0015459 potassium channel regulator activity PIRSF:PIRSF500980
PR:Q8R523-1 rKCNG3/iso:1 acts_upstream_of_or_withinGO:0006813 potassium ion transport PMID:15046870
enablescontributes_to GO:0005249 voltage-gated potassium channel activity PMID:15046870
PR:Q8R523-2 rKCNG3/iso:2 acts_upstream_of_or_withinGO:0006813 potassium ion transport PMID:15046870
enablesGO:0005249 voltage-gated potassium channel activity PMID:15046870
PR:Q8TAE7-1 hKCNG3/iso:1 located_inGO:0005783 endoplasmic reticulum PMID:12060745
GO:0005886 plasma membrane PMID:12060745