back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
PR:000000705 - http://purl.obolibrary.org/obo/PR_000000705
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000705   
  PRO namepotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 
  Synonyms
PRO-Short-label: EXACT:HCN1
Gene-based: RELATED:BCNG1 | Hac2
Other: EXACT:BCNG-1 | brain cyclic nucleotide-gated channel 1 | HAC-2 | hyperpolarization-activated cation channel 2
  Definition"A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel protein that is a translation product of the human HCN1 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000676 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 1                                        
         Modification2                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
IUPHARobj:400
Back to top
Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000000705

potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

HCN1


"A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel protein that is a translation product of the human HCN1 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:O60741

potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (human)

hHCN1


"A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:O60741]


organism-gene



PR:O88704

potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (mouse)

mHCN1


"A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 that is encoded in the genome of mouse." [OMA:O88704, PRO:DNx]


organism-sequence



PR:O88704-1

potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 (mouse)

mHCN1/iso:1


"A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-modification



PR:000036573

potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 N-glycosylated 1 (mouse)

mHCN1/iso:1/NGlyco:1


"A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 N-glycosylated 1 in mouse. UniProtKB:O88704-1, Asn-327, MOD:00160." [PMID:12928435, PRO:CNA, PRO:DAN]

Yes

organism-gene



PR:Q9JKB0

potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (rat)

rHCN1


"A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 that is encoded in the genome of rat." [OMA:Q9JKB0, PRO:DNx]


sequence



PR:000000755

potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1

HCN1/iso:1


"A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88704-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:O88704-1

potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 (mouse)

mHCN1/iso:1


"A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-modification



PR:000036573

potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 N-glycosylated 1 (mouse)

mHCN1/iso:1/NGlyco:1


"A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 N-glycosylated 1 in mouse. UniProtKB:O88704-1, Asn-327, MOD:00160." [PMID:12928435, PRO:CNA, PRO:DAN]

Yes

modification



PR:000000935

potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 glycosylated form

HCN1/iso:1/GlycoRes+


"A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 that includes at least one glycosylated residue." [PRO:CNA]


modification



PR:000000984

potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 N-glycosylated 1

HCN1/iso:1/NGlyco:1


"A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 glycosylated form with N-glycosylation at the N-linked glycosylation consensus sequence (Nx[ST]) in the extracellular domain between S5 and S6 transmembrane segments. Example: UniProtKB:O88704-1, Asn-327, MOD:00160." [PMID:17988239]


organism-modification



PR:000036573

potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 N-glycosylated 1 (mouse)

mHCN1/iso:1/NGlyco:1


"A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 isoform 1 N-glycosylated 1 in mouse. UniProtKB:O88704-1, Asn-327, MOD:00160." [PMID:12928435, PRO:CNA, PRO:DAN]

Yes

Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036573 mHCN1/iso:1/NGlyco:1
UniProtKB:O88704-1, Asn-327, MOD:00160
located_inGO:0009986 cell surface PMID:12928435
PR:O88704-1 mHCN1/iso:1 acts_upstream_of_or_withinGO:0006812 monoatomic cation transport PMID:9630217
enablescontributes_to GO:0005222 intracellularly cAMP-activated cation channel activity PMID:11459060; PMID:9630217
GO:0005261 monoatomic cation channel activity PMID:9630217
GO:0022843 voltage-gated monoatomic cation channel activity PMID:9634236
located_inGO:0009986 cell surface PMID:15564593
GO:0030424 axon PMID:15479642
GO:0032991 protein-containing complex PMID:12034718