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Protein Ontology report - shaw-related voltage-gated potassium channel alpha subunit
PR:000000711 - http://purl.obolibrary.org/obo/PR_000000711
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000711   
  PRO nameshaw-related voltage-gated potassium channel alpha subunit 
  Synonyms
PRO-Short-label: EXACT:fam:Kchan_shaw_sub-a
Other: RELATED:Kv3 channel
  Definition"A voltage-gated potassium channel alpha subunit that is a constituent of Kv3 channels. These proteins are characterized by the high sequence conservation in the S5 segment which seems to determine the gating properties of the Kv3 channels: rightward shifted voltage dependence and fast deactivation rates. They also contain an ATM motif at the lysine-rich C-terminal region that is unique to this group. Kv3 channels are necessary for high-frequency, repetitive firing of action potentials. High activation threshold is a hallmark of Kv3 channels. They regulate rapid spiking, transmitter release and dendritic integration of many central neurons. In common with Kv2 and Kv4 channels, the tetramerization domain at the N terminus contains a zinc-binding site." [PMID:11506885
  PRO Categoryfamily 
  ParentPR:000000685 voltage-gated potassium channel alpha subunit
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene4                                                  Organism-Gene 13                                        
         Sequence8                                                  Organism-Sequence 21                                        
         Modification5                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF500973
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000000711

shaw-related voltage-gated potassium channel alpha subunit

fam:Kchan_shaw_sub-a


"A voltage-gated potassium channel alpha subunit that is a constituent of Kv3 channels. These proteins are characterized by the high sequence conservation in the S5 segment which seems to determine the gating properties of the Kv3 channels: rightward shifted voltage dependence and fast deactivation rates. They also contain an ATM motif at the lysine-rich C-terminal region that is unique to this group. Kv3 channels are necessary for high-frequency, repetitive firing of action potentials. High activation threshold is a hallmark of Kv3 channels. They regulate rapid spiking, transmitter release and dendritic integration of many central neurons. In common with Kv2 and Kv4 channels, the tetramerization domain at the N terminus contains a zinc-binding site." [PMID:11506885]


gene



PR:000000781

voltage-gated potassium channel KCNC1

KCNC1


"A shaw-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNC1 gene or a 1:1 ortholog thereof. They contain an ATM motif at the C-terminus, following the S6 segment that allows interaction with axonal targeting machinery when exposed." [PRO:CNA]


organism-gene



PR:P15388

voltage-gated potassium channel KCNC1 (mouse)

mKCNC1


"A voltage-gated potassium channel KCNC1 that is encoded in the genome of mouse." [OMA:P15388, PRO:DNx]


organism-sequence



PR:P15388-1

voltage-gated potassium channel KCNC1, isoform Short (mouse)

mKCNC1/iso:Short


"A voltage-gated potassium channel KCNC1 isoform Short that is encoded in the genome of mouse." [PMID:2599109, PRO:HJD]


organism-sequence



PR:P15388-3

voltage-gated potassium channel KCNC1, isoform Long (mouse)

mKCNC1/iso:Long


"A voltage-gated potassium channel KCNC1 isoform Long that is encoded in the genome of mouse." [PMID:2599109, PRO:HJD, RefSeq:NP_001106210]


organism-gene



PR:P25122

voltage-gated potassium channel KCNC1 (rat)

rKCNC1


"A voltage-gated potassium channel KCNC1 that is encoded in the genome of rat." [OMA:P25122, PRO:DNx]


organism-sequence



PR:P25122-1

voltage-gated potassium channel KCNC1 isoform Long (rat)

rKCNC1/iso:Long


"A voltage-gated potassium channel KCNC1 isoform Long that is encoded in the genome of rat." [PRO:CNA]

Yes

organism-modification



PR:000036575

voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 (rat)

rKCNC1/iso:Long/Phos:1


"A voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 in rat. UniProtKB:P25122-1, Ser-503, MOD:00046." [PMID:16595659, PRO:CNA]

Yes

organism-modification



PR:000045386

voltage-gated potassium channel KCNC1 isoform Long unphosphorylated 1 (rat)

rKCNC1/iso:Long/UnPhos:1


"A voltage-gated potassium channel KCNC1 isoform Long (rat) that lacks phosphorylation on Ser-503. UniProtKB:P25122-1, Ser-503, PR:000026291." [PMID:16595659, PRO:CNA]

Yes

organism-sequence



PR:P25122-2

voltage-gated potassium channel KCNC1 isoform Short (rat)

rKCNC1/iso:Short


"A voltage-gated potassium channel KCNC1 isoform Short that is encoded in the genome of rat." [PRO:CNA]

Yes

organism-gene



PR:P48547

voltage-gated potassium channel KCNC1 (human)

hKCNC1


"A voltage-gated potassium channel KCNC1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P48547]


organism-sequence



PR:P48547-1

voltage-gated potassium channel KCNC1 isoform 1 (human)

hKCNC1/iso:1


"A voltage-gated potassium channel KCNC1 isoform Short that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:P48547-2

voltage-gated potassium channel KCNC1 isoform h2 (human)

hKCNC1/iso:h2


"A voltage-gated potassium channel KCNC1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48547-2." [PRO:DNx, UniProtKB:P48547]


sequence



PR:000000939

voltage-gated potassium channel KCNC1 isoform Short

KCNC1/iso:Short


"A voltage-gated potassium channel KCNC1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48547-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P15388-1

voltage-gated potassium channel KCNC1, isoform Short (mouse)

mKCNC1/iso:Short


"A voltage-gated potassium channel KCNC1 isoform Short that is encoded in the genome of mouse." [PMID:2599109, PRO:HJD]


organism-sequence



PR:P25122-2

voltage-gated potassium channel KCNC1 isoform Short (rat)

rKCNC1/iso:Short


"A voltage-gated potassium channel KCNC1 isoform Short that is encoded in the genome of rat." [PRO:CNA]

Yes

organism-sequence



PR:P48547-1

voltage-gated potassium channel KCNC1 isoform 1 (human)

hKCNC1/iso:1


"A voltage-gated potassium channel KCNC1 isoform Short that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000000940

voltage-gated potassium channel KCNC1 isoform Long

KCNC1/iso:Long


"A voltage-gated potassium channel KCNC1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P25122-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P15388-3

voltage-gated potassium channel KCNC1, isoform Long (mouse)

mKCNC1/iso:Long


"A voltage-gated potassium channel KCNC1 isoform Long that is encoded in the genome of mouse." [PMID:2599109, PRO:HJD, RefSeq:NP_001106210]


organism-sequence



PR:P25122-1

voltage-gated potassium channel KCNC1 isoform Long (rat)

rKCNC1/iso:Long


"A voltage-gated potassium channel KCNC1 isoform Long that is encoded in the genome of rat." [PRO:CNA]

Yes

organism-modification



PR:000036575

voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 (rat)

rKCNC1/iso:Long/Phos:1


"A voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 in rat. UniProtKB:P25122-1, Ser-503, MOD:00046." [PMID:16595659, PRO:CNA]

Yes

organism-modification



PR:000045386

voltage-gated potassium channel KCNC1 isoform Long unphosphorylated 1 (rat)

rKCNC1/iso:Long/UnPhos:1


"A voltage-gated potassium channel KCNC1 isoform Long (rat) that lacks phosphorylation on Ser-503. UniProtKB:P25122-1, Ser-503, PR:000026291." [PMID:16595659, PRO:CNA]

Yes

modification



PR:000000986

voltage-gated potassium channel KCNC1 isoform Long phosphorylated form

KCNC1/iso:Long/PhosRes+


"A voltage-gated potassium channel KCNC1 isoform Long that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000000992

voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1

KCNC1/iso:Long/Phos:1


"A voltage-gated potassium channel KCNC1 isoform Long phosphorylated form in which the phosphorylation occurs by the action of PKC at the Ser residue within the DSKL motif located in the C-terminal tail. In resting neurons, basal phosphorylation at this site decreases Kv3.1 channel current, reducing neuronal ability to follow high frequency stimulation. Example: UniProtKB:P25122-1, Ser-503, MOD:00046." [PMID:16595659]


organism-modification



PR:000036575

voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 (rat)

rKCNC1/iso:Long/Phos:1


"A voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 in rat. UniProtKB:P25122-1, Ser-503, MOD:00046." [PMID:16595659, PRO:CNA]

Yes

gene



PR:000000782

voltage-gated potassium channel KCNC2

KCNC2


"A shaw-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNC2 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P22462

voltage-gated potassium channel KCNC2 (rat)

rKCNC2


"A voltage-gated potassium channel KCNC2 that is encoded in the genome of rat." [OMA:P22462, PRO:DNx]


organism-sequence



PR:P22462-1

potassium voltage-gated channel subfamily C member 2 isoform KV3.2B (rat)

rKCNC2/iso:KV3.2B


"A voltage-gated potassium channel KCNC2 isoform 1 that is encoded in the genome of rat." [PRO:DNx, UniProtKB:P22462]

Yes

organism-sequence



PR:P22462-2

voltage-gated potassium channel KCNC2 isoform r2 (rat)

rKCNC2/iso:r2


"A voltage-gated potassium channel KCNC2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22462-2." [PRO:DNx, UniProtKB:P22462]


organism-sequence



PR:P22462-3

potassium voltage-gated channel subfamily C member 2 isoform KSHIIIA.1 (rat)

rKCNC2/iso:KSHIIIA.1


"A voltage-gated potassium channel KCNC2 isoform 3 that is encoded in the genome of rat." [PRO:CNA]

Yes

organism-sequence



PR:P22462-4

voltage-gated potassium channel KCNC2 isoform r4 (rat)

rKCNC2/iso:r4


"A voltage-gated potassium channel KCNC2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22462-4." [PRO:DNx, UniProtKB:P22462]


organism-gene



PR:Q14B80

voltage-gated potassium channel KCNC2 (mouse)

mKCNC2


"A voltage-gated potassium channel KCNC2 that is encoded in the genome of mouse." [OMA:Q14B80, PRO:DNx]


organism-gene



PR:Q96PR1

voltage-gated potassium channel KCNC2 (human)

hKCNC2


"A voltage-gated potassium channel KCNC2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q96PR1]


organism-sequence



PR:Q96PR1-1

voltage-gated potassium channel KCNC2 isoform 1 (human)

hKCNC2/iso:1


"A voltage-gated potassium channel KCNC2 isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96PR1]


organism-sequence



PR:Q96PR1-2

voltage-gated potassium channel KCNC2 isoform 2 (human)

hKCNC2/iso:2


"A voltage-gated potassium channel KCNC2 isoform 2 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q96PR1-3

voltage-gated potassium channel KCNC2 isoform 3 (human)

hKCNC2/iso:3


"A voltage-gated potassium channel KCNC2 isoform 3 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q96PR1-4

voltage-gated potassium channel KCNC2 isoform 4 (human)

hKCNC2/iso:4


"A voltage-gated potassium channel KCNC2 isoform 4 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q96PR1-5

voltage-gated potassium channel KCNC2 isoform h5 (human)

hKCNC2/iso:h5


"A voltage-gated potassium channel KCNC2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PR1-5." [PRO:DNx, UniProtKB:Q96PR1]


organism-sequence



PR:Q96PR1-6

voltage-gated potassium channel KCNC2 isoform h6 (human)

hKCNC2/iso:h6


"A voltage-gated potassium channel KCNC2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PR1-6." [PRO:DNx, UniProtKB:Q96PR1]


sequence



PR:000000941

voltage-gated potassium channel KCNC2 isoform 1

KCNC2/iso:1


"A voltage-gated potassium channel KCNC2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22462-1 or a 1:1 ortholog thereof." [PMID:1879548, PRO:CNA, PRO:DAN]


organism-sequence



PR:P22462-1

potassium voltage-gated channel subfamily C member 2 isoform KV3.2B (rat)

rKCNC2/iso:KV3.2B


"A voltage-gated potassium channel KCNC2 isoform 1 that is encoded in the genome of rat." [PRO:DNx, UniProtKB:P22462]

Yes

organism-sequence



PR:Q96PR1-1

voltage-gated potassium channel KCNC2 isoform 1 (human)

hKCNC2/iso:1


"A voltage-gated potassium channel KCNC2 isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96PR1]


sequence



PR:000000942

voltage-gated potassium channel KCNC2 isoform 2

KCNC2/iso:2


"A voltage-gated potassium channel KCNC2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PR1-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:Q96PR1-2

voltage-gated potassium channel KCNC2 isoform 2 (human)

hKCNC2/iso:2


"A voltage-gated potassium channel KCNC2 isoform 2 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000000943

voltage-gated potassium channel KCNC2 isoform 3

KCNC2/iso:3


"A voltage-gated potassium channel KCNC2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PR1-3 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P22462-3

potassium voltage-gated channel subfamily C member 2 isoform KSHIIIA.1 (rat)

rKCNC2/iso:KSHIIIA.1


"A voltage-gated potassium channel KCNC2 isoform 3 that is encoded in the genome of rat." [PRO:CNA]

Yes

organism-sequence



PR:Q96PR1-3

voltage-gated potassium channel KCNC2 isoform 3 (human)

hKCNC2/iso:3


"A voltage-gated potassium channel KCNC2 isoform 3 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000000944

voltage-gated potassium channel KCNC2 isoform 4

KCNC2/iso:4


"A voltage-gated potassium channel KCNC2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PR1-4 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:Q96PR1-4

voltage-gated potassium channel KCNC2 isoform 4 (human)

hKCNC2/iso:4


"A voltage-gated potassium channel KCNC2 isoform 4 that is encoded in the genome of human." [PRO:CNA]


gene



PR:000000783

voltage-gated potassium channel KCNC4

KCNC4


"A shaw-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNC4 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:E1C3U8

uncharacterized protein, KCNC4 translation product (chicken)

chick-KCNC4


"A voltage-gated potassium channel KCNC4 that is encoded in the genome of chicken." [OMA:E1C3U8, PRO:CNA]


organism-gene



PR:Q03721

voltage-gated potassium channel KCNC4 (human)

hKCNC4


"A voltage-gated potassium channel KCNC4 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q03721]


organism-sequence



PR:Q03721-1

voltage-gated potassium channel KCNC4 isoform 1 (human)

hKCNC4/iso:1


"A voltage-gated potassium channel KCNC4 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q03721-2

voltage-gated potassium channel KCNC4 isoform 2 (human)

hKCNC4/iso:2


"A voltage-gated potassium channel KCNC4 isoform 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q03721]


organism-modification



PR:000036576

voltage-gated potassium channel KCNC4 isoform 2 phosphorylated 1 (human)

hKCNC4/iso:2/Phos:1


"A voltage-gated potassium channel KCNC4 isoform 2 phosphorylated 1 in human. UniProtKB:Q03721-2, Ser-8/Ser-9/Ser-15/Ser-21, MOD:00046." [PMID:7993631, PMID:9649584, PRO:CNA]

Yes

organism-modification



PR:000045387

voltage-gated potassium channel KCNC4 isoform 2 unphosphorylated 1 (human)

hKCNC4/iso:2/UnPhos:1


"A voltage-gated potassium channel KCNC4 isoform 2 (human) that lacks phosphorylation on Ser-8, Ser-9, Ser-15 and Ser-21. UniProtKB:Q03721-2, Ser-8/Ser-9/Ser-15/Ser-21, PR:000026291." [PMID:7993631, PMID:9649584, PRO:CNA]

Yes

organism-sequence



PR:Q03721-3

voltage-gated potassium channel KCNC4 isoform h3 (human)

hKCNC4/iso:h3


"A voltage-gated potassium channel KCNC4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03721-3." [PRO:DNx, UniProtKB:Q03721]


organism-gene



PR:Q63734

voltage-gated potassium channel KCNC4 (rat)

rKCNC4


"A voltage-gated potassium channel KCNC4 that is encoded in the genome of rat." [OMA:Q63734, PRO:DNx]


organism-gene



PR:Q8R1C0

voltage-gated potassium channel KCNC4 (mouse)

mKCNC4


"A voltage-gated potassium channel KCNC4 that is encoded in the genome of mouse." [OMA:Q8R1C0, PRO:DNx]


sequence



PR:000000945

voltage-gated potassium channel KCNC4 isoform 1

KCNC4/iso:1


"A voltage-gated potassium channel KCNC4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03721-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:Q03721-1

voltage-gated potassium channel KCNC4 isoform 1 (human)

hKCNC4/iso:1


"A voltage-gated potassium channel KCNC4 isoform 1 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000000946

voltage-gated potassium channel KCNC4 isoform 2

KCNC4/iso:2


"A voltage-gated potassium channel KCNC4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03721-2 or a 1:1 ortholog thereof." [PMID:1381835, PRO:CNA, PRO:DAN]


organism-sequence



PR:Q03721-2

voltage-gated potassium channel KCNC4 isoform 2 (human)

hKCNC4/iso:2


"A voltage-gated potassium channel KCNC4 isoform 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q03721]


organism-modification



PR:000036576

voltage-gated potassium channel KCNC4 isoform 2 phosphorylated 1 (human)

hKCNC4/iso:2/Phos:1


"A voltage-gated potassium channel KCNC4 isoform 2 phosphorylated 1 in human. UniProtKB:Q03721-2, Ser-8/Ser-9/Ser-15/Ser-21, MOD:00046." [PMID:7993631, PMID:9649584, PRO:CNA]

Yes

organism-modification



PR:000045387

voltage-gated potassium channel KCNC4 isoform 2 unphosphorylated 1 (human)

hKCNC4/iso:2/UnPhos:1


"A voltage-gated potassium channel KCNC4 isoform 2 (human) that lacks phosphorylation on Ser-8, Ser-9, Ser-15 and Ser-21. UniProtKB:Q03721-2, Ser-8/Ser-9/Ser-15/Ser-21, PR:000026291." [PMID:7993631, PMID:9649584, PRO:CNA]

Yes

modification



PR:000000987

voltage-gated potassium channel KCNC4 isoform 2 phosphorylated form

KCNC4/iso:2/PhosRes+


"A voltage-gated potassium channel KCNC4 isoform 2 that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000000993

voltage-gated potassium channel KCNC4 isoform 2 phosphorylated 1

KCNC4/iso:2/Phos:1


"A voltage-gated potassium channel KCNC4 isoform 2 phosphorylated form in which the phosphorylation occurs by the action of PKC at multiple Ser residues located in the N-terminal domain. Example: UniProtKB:Q03721-2, Ser-8/Ser-9/Ser-15/Ser-21, MOD:00046." [PRO:CNA]


organism-modification



PR:000036576

voltage-gated potassium channel KCNC4 isoform 2 phosphorylated 1 (human)

hKCNC4/iso:2/Phos:1


"A voltage-gated potassium channel KCNC4 isoform 2 phosphorylated 1 in human. UniProtKB:Q03721-2, Ser-8/Ser-9/Ser-15/Ser-21, MOD:00046." [PMID:7993631, PMID:9649584, PRO:CNA]

Yes

modification



PR:000002655

voltage-gated potassium channel KCNC4 isoform 2 unmodified form

KCNC4/iso:2/UnMod


"A voltage-gated potassium channel KCNC4 isoform 2 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]


gene



PR:000009254

voltage-gated potassium channel KCNC3

KCNC3


"A shaw-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNC3 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q01956

voltage-gated potassium channel KCNC3 (rat)

rKCNC3


"A voltage-gated potassium channel KCNC3 that is encoded in the genome of rat." [OMA:Q01956, PRO:DNx]


organism-sequence



PR:Q01956-1

voltage-gated potassium channel KCNC3 isoform rKSHIIID.1 (rat)

rKCNC3/iso:rKSHIIID.1


"A voltage-gated potassium channel KCNC3 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01956-1." [PRO:DNx, UniProtKB:Q01956]


organism-sequence



PR:Q01956-2

voltage-gated potassium channel KCNC3 isoform rKSHIIID.2 (rat)

rKCNC3/iso:rKSHIIID.2


"A voltage-gated potassium channel KCNC3 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01956-2." [PRO:DNx, UniProtKB:Q01956]


organism-gene



PR:Q14003

voltage-gated potassium channel KCNC3 (human)

hKCNC3


"A voltage-gated potassium channel KCNC3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q14003]


organism-gene



PR:Q63959

voltage-gated potassium channel KCNC3 (mouse)

mKCNC3


"A voltage-gated potassium channel KCNC3 that is encoded in the genome of mouse." [OMA:Q63959, PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036575 rKCNC1/iso:Long/Phos:1
UniProtKB:P25122-1, Ser-503, MOD:00046
enablesdecreased|contributes_to GO:0005249 voltage-gated potassium channel activity relative to PR:000002649 PMID:16595659
located_inGO:0016020 membrane PMID:16595659
PR:000036576 hKCNC4/iso:2/Phos:1
UniProtKB:Q03721-2, Ser-8/Ser-9/Ser-15/Ser-21, MOD:00046
enablesdecreased|contributes_to GO:0005250 A-type (transient outward) potassium channel activity relative to PR:000002655 KCNC4/iso:2/UnMod PMID:7993631; PMID:9649584
PR:000045386 rKCNC1/iso:Long/UnPhos:1
UniProtKB:P25122-1, Ser-503, PR:000026291
enablescontributes_to GO:0005249 voltage-gated potassium channel activity PMID:16595659
PR:000045387 hKCNC4/iso:2/UnPhos:1
UniProtKB:Q03721-2, Ser-8/Ser-9/Ser-15/Ser-21, PR:000026291
enablescontributes_to GO:0005250 A-type (transient outward) potassium channel activity PMID:1381835; PMID:7993631; PMID:9649584
PR:P22462-1 rKCNC2/iso:KV3.2B enablescontributes_to GO:0015271 outward rectifier potassium channel activity PMID:1879548
PR:P22462-3 rKCNC2/iso:KSHIIIA.1 enablescontributes_to GO:0005249 voltage-gated potassium channel activity PMID:10414303; PMID:11506885
PR:P25122-1 rKCNC1/iso:Long enablesGO:0030506 ankyrin binding with PR:O70511 ANK-3 (rat) PMID:18094255
located_inGO:0030424 axon PMID:18094255
PR:P25122-2 rKCNC1/iso:Short located_inGO:0032809 neuronal cell body membrane PMID:18094255