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Protein Ontology report - transient receptor potential cation channel TRPC3/6/7
PR:000000718 - http://purl.obolibrary.org/obo/PR_000000718
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000718   
  PRO nametransient receptor potential cation channel TRPC3/6/7 
  Synonyms
PRO-Short-label: EXACT:fam:TRPC[3/6/7]
Other: RELATED:DAG-sensitive TRPC
  Definition"A transient receptor potential cation channel TRPC that is a member of a subgroup of subfamily C containing the very similar TRPC3, TRPC6, and TRPC7. They form homomeric or heteromeric nonselective cation channels that generate double-rectifying currents and are activated by diacylglycerol." [PMID:16382100, PMID:16460286, PMID:17579562] 
  PRO Categoryfamily 
  ParentPR:000000680 transient receptor potential cation channel TRPC
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene3                                                  Organism-Gene 8                                        
         Sequence2                                                  Organism-Sequence 10                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF500999
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000000718 transient receptor potential cation channel TRPC3/6/7
fam:TRPC[3/6/7]

gene


PR:000000775 short transient receptor potential cation channel TRPC3
TRPC3

organism-gene


PR:P34586 transient-receptor-potential-like protein (worm)
TRPC3 (worm)

organism-gene


PR:Q13507 short transient receptor potential channel 3 (human)
hTRPC3

organism-sequence


PR:Q13507-1 short transient receptor potential channel 3 isoform 1 (human)
hTRPC3/iso:1
Yes
organism-sequence


PR:Q13507-2 short transient receptor potential channel 3 isoform h1 (human)
hTRPC3/iso:h1

organism-sequence


PR:Q13507-3 short transient receptor potential channel 3 isoform h2 (human)
hTRPC3/iso:h2

organism-gene


PR:Q9JMI9 short transient receptor potential channel 3 (rat)
rTRPC3

organism-gene


PR:Q9QZC1 short transient receptor potential channel 3 (mouse)
mTRPC3

sequence


PR:000000937 short transient receptor potential cation channel TRPC3 isoform 1
TRPC3/iso:1

organism-sequence


PR:Q13507-1 short transient receptor potential channel 3 isoform 1 (human)
hTRPC3/iso:1
Yes
gene


PR:000001080 short transient receptor potential cation channel TRPC7
TRPC7

organism-gene


PR:Q9HCX4 short transient receptor potential channel 7 (human)
hTRPC7
Yes
organism-sequence


PR:Q9HCX4-1 short transient receptor potential channel 7 isoform 1 (human)
hTRPC7/iso:1

organism-sequence


PR:Q9HCX4-2 short transient receptor potential channel 7 isoform h2 (human)
hTRPC7/iso:h2

organism-sequence


PR:Q9HCX4-3 short transient receptor potential channel 7 isoform h3 (human)
hTRPC7/iso:h3

organism-gene


PR:Q9WVC5 short transient receptor potential channel 7 (mouse)
mTRPC7

organism-sequence


PR:Q9WVC5-1 short transient receptor potential channel 7 isoform 1 (mouse)
mTRPC7/iso:1
Yes
sequence


PR:000001081 short transient receptor potential cation channel TRPC7 isoform 1
TRPC7/iso:1

organism-sequence


PR:Q9HCX4-1 short transient receptor potential channel 7 isoform 1 (human)
hTRPC7/iso:1

organism-sequence


PR:Q9WVC5-1 short transient receptor potential channel 7 isoform 1 (mouse)
mTRPC7/iso:1
Yes
gene


PR:000016696 short transient receptor potential channel 6
TRPC6

organism-gene


PR:Q61143 short transient receptor potential channel 6 (mouse)
mTRPC6

organism-gene


PR:Q9Y210 short transient receptor potential channel 6 (human)
hTRPC6

organism-sequence


PR:Q9Y210-1 short transient receptor potential channel 6 isoform h1 (human)
hTRPC6/iso:h1

organism-sequence


PR:Q9Y210-2 short transient receptor potential channel 6 isoform h2 (human)
hTRPC6/iso:h2

organism-sequence


PR:Q9Y210-3 short transient receptor potential channel 6 isoform h3 (human)
hTRPC6/iso:h3

organism-modification


PR:000058350 short transient receptor potential channel 6 N-glycosylated 1 (human)
hTRPC6/NGlyco:1

organism-modification


PR:000058351 short transient receptor potential channel 6 N-glycosylated 2 (human)
hTRPC6/NGlyco:2

organism-modification


PR:000072935 short transient receptor potential channel 6 phosphorylated 1 (human)
hTRPC6/Phos:1

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0006816 calcium ion transportPR:Q9WVC5-1 mTRPC7/iso:1 PMID:10488066
GO:0007602 phototransductionPR:Q13507-1 hTRPC3/iso:1 PMID:9215637

Molecular Function GO Term
Protein Forms & Complexes
Evidence
contributes_to GO:0005262 calcium channel activityPR:Q9WVC5-1 mTRPC7/iso:1 PMID:10488066
GO:0005515 protein bindingPR:Q13507-1 hTRPC3/iso:1 PMID:15744307
PR:Q9HCX4 hTRPC7 PMID:15757897
contributes_to GO:0006828 manganese ion transportPR:Q9WVC5-1 mTRPC7/iso:1 PMID:10488066
GO:0015279 store-operated calcium channel activityPR:Q13507-1 hTRPC3/iso:1 PMID:9215637

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005886 plasma membranePR:Q13507-1 hTRPC3/iso:1 PMID:9368034
GO:0016020 membranePR:Q9WVC5-1 mTRPC7/iso:1 PMID:10488066