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Protein Ontology report - platelet-derived growth factor C isoform 1
PR:000000754 - http://purl.obolibrary.org/obo/PR_000000754
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000754   
  PRO nameplatelet-derived growth factor C isoform 1 
  Synonyms
PRO-Short-label: EXACT:PDGFC/iso:1
  Definition"A platelet-derived growth factor C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NRA1-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000703 platelet-derived growth factor C
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification4                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
sequence



PR:000000754

platelet-derived growth factor C isoform 1

PDGFC/iso:1


"A platelet-derived growth factor C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NRA1-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:Q8CI19-1

platelet-derived growth factor C isoform 1 (mouse)

mPDGFC/iso:1


"A platelet-derived growth factor C isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-modification



PR:000036571

platelet-derived growth factor C isoform 1 cleaved 1 (mouse)

mPDGFC/iso:1/Clv:1


"A platelet-derived growth factor C isoform 1 cleaved 1 in mouse. UniProtKB:Q8CI19-1, 226-345." [PMID:11297552, PMID:15372073, PRO:CNA]

Yes

organism-sequence



PR:Q9NRA1-1

platelet-derived growth factor C isoform 1 (human)

hPDGFC/iso:1


"A platelet-derived growth factor C isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000036572

platelet-derived growth factor C isoform 1 mono-SUMO1-ylated form (human)

hPDGFC/iso:1/Sumo1+


"A platelet-derived growth factor C isoform 1 mono-SUMO1-ylated form in human. UniProtKB:Q9NRA1-1, MOD:01149~PR:000050074." [PMID:16443219, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000063004

platelet-derived growth factor C isoform 1, signal peptide removed form (human)

hPDGFC/iso:1/SigPep-


"A platelet-derived growth factor C isoform 1 (human) that has had the signal peptide removed. UniProtKB:Q9NRA1-1, 23-345." [PRO:DNx, Reactome:R-HSA-381905]


organism-modification



PR:000036570

platelet-derived growth factor C isoform 1 cleaved 1 (human)

hPDGFC/iso:1/Clv:1


"A platelet-derived growth factor C isoform 1 cleaved 1 in human. UniProtKB:Q9NRA1-1, 226-345." [PMID:10806482, PMID:11297552, PMID:15911618, PRO:CNA]

Yes

modification



PR:000000934

platelet-derived growth factor C isoform 1 sumoylated form

PDGFC/iso:1/SumoLys+


"A platelet-derived growth factor C isoform 1 that includes at least one sumoylated lysine." [PRO:CNA]


modification



PR:000000983

platelet-derived growth factor C isoform 1 mono-SUMO1-ylated form

PDGFC/iso:1/Sumo1+


"A platelet-derived growth factor C isoform 1 sumoylated form in which the sumoylation conjugate is SUMO1. Example: UniProtKB:Q9NRA1-1, Lys-314, MOD:01149~PR:000050074." [PMID:16443219, PRO:CNA, PRO:DAN]


organism-modification



PR:000036572

platelet-derived growth factor C isoform 1 mono-SUMO1-ylated form (human)

hPDGFC/iso:1/Sumo1+


"A platelet-derived growth factor C isoform 1 mono-SUMO1-ylated form in human. UniProtKB:Q9NRA1-1, MOD:01149~PR:000050074." [PMID:16443219, PRO:CNA, PRO:DAN]

Yes

modification



PR:000021917

platelet-derived growth factor C isoform 1, signal peptide removed form

PDGFC/iso:1/SigPep-


"A platelet-derived growth factor C isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000000982

platelet-derived growth factor C isoform 1 cleaved 1

PDGFC/iso:1/Clv:1


"A platelet-derived growth factor C isoform 1, signal peptide removed form that has been processed by subsequent removal of the CUB domain." [PRO:CNA]


organism-modification



PR:000036570

platelet-derived growth factor C isoform 1 cleaved 1 (human)

hPDGFC/iso:1/Clv:1


"A platelet-derived growth factor C isoform 1 cleaved 1 in human. UniProtKB:Q9NRA1-1, 226-345." [PMID:10806482, PMID:11297552, PMID:15911618, PRO:CNA]

Yes

organism-modification



PR:000036571

platelet-derived growth factor C isoform 1 cleaved 1 (mouse)

mPDGFC/iso:1/Clv:1


"A platelet-derived growth factor C isoform 1 cleaved 1 in mouse. UniProtKB:Q8CI19-1, 226-345." [PMID:11297552, PMID:15372073, PRO:CNA]

Yes

organism-modification



PR:000063004

platelet-derived growth factor C isoform 1, signal peptide removed form (human)

hPDGFC/iso:1/SigPep-


"A platelet-derived growth factor C isoform 1 (human) that has had the signal peptide removed. UniProtKB:Q9NRA1-1, 23-345." [PRO:DNx, Reactome:R-HSA-381905]


organism-modification



PR:000036570

platelet-derived growth factor C isoform 1 cleaved 1 (human)

hPDGFC/iso:1/Clv:1


"A platelet-derived growth factor C isoform 1 cleaved 1 in human. UniProtKB:Q9NRA1-1, 226-345." [PMID:10806482, PMID:11297552, PMID:15911618, PRO:CNA]

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036570 hPDGFC/iso:1/Clv:1
UniProtKB:Q9NRA1-1, 226-345
enablesGO:0005102 signaling receptor binding PMID:10806482; PMID:11297552
GO:0008083 growth factor activity PMID:10806482; PMID:11297552
located_inGO:0005615 extracellular space PMID:15911618
PR:000036571 mPDGFC/iso:1/Clv:1
UniProtKB:Q8CI19-1, 226-345
acts_upstream_of_or_withinGO:0042060 wound healing PMID:11297552
located_inGO:0005615 extracellular space PMID:15372073
PR:000036572 hPDGFC/iso:1/Sumo1+
UniProtKB:Q9NRA1-1, MOD:01149~PR:000050074
located_inGO:0005634 nucleus PMID:16443219