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Protein Ontology report - voltage-gated potassium channel subunit KCNA2
PR:000000810 - http://purl.obolibrary.org/obo/PR_000000810
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000810   
  PRO namevoltage-gated potassium channel subunit KCNA2 
  Synonyms
PRO-Short-label: EXACT:KCNA2
Other: EXACT:NGK1 | voltage-gated K(+) channel HuKIV | voltage-gated potassium channel HBK5 | voltage-gated potassium channel subunit Kv1.2
RELATED:MK2
  Definition"A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA2 gene or a 1:1 ortholog thereof. The Kv1.2 channel is involved in maintaining membrane potential, modulating electrical excitability in neurons and muscle. It can coassemble with other Kv1 subunits." [PMID:16382104] 
  PRO Categorygene 
  ParentPR:000000709 shaker-related voltage-gated potassium channel alpha subunit
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 11                                        
         Modification3                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:539
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000000810 voltage-gated potassium channel subunit KCNA2
KCNA2

organism-gene


PR:P16389 potassium voltage-gated channel subfamily A member 2 (human)
hKCNA2

organism-sequence


PR:P16389-1 potassium voltage-gated channel subfamily A member 2 isoform 1 (human)
hKCNA2/iso:1
Yes
organism-modification


PR:000036584 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 (human)
hKCNA2/iso:1/Phos:1
Yes
organism-modification


PR:000036587 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (human)
hKCNA2/iso:1/Phos:2
Yes
organism-sequence


PR:P16389-2 potassium voltage-gated channel subfamily A member 2 isoform h2 (human)
hKCNA2/iso:h2

organism-gene


PR:P63141 potassium voltage-gated channel subfamily A member 2 (mouse)
mKCNA2

organism-sequence


PR:P63141-1 potassium voltage-gated channel subfamily A member 2 isoform 1 (mouse)
mKCNA2/iso:1

organism-modification


PR:000036585 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (mouse)
mKCNA2/iso:1/Phos:2
Yes
organism-gene


PR:P63142 potassium voltage-gated channel subfamily A member 2 (rat)
rKCNA2

organism-sequence


PR:P63142-1 potassium voltage-gated channel subfamily A member 2 isoform 1 (rat)
rKCNA2/iso:1
Yes
organism-modification


PR:000036586 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (rat)
rKCNA2/iso:1/Phos:2
Yes
organism-gene


PR:Q8I4B0 potassium voltage-gated channel protein shk-1 (worm)
KCNA2 (worm)

organism-sequence


PR:Q8I4B0-1 potassium voltage-gated channel protein shk-1 isoform c (worm)
KCNA2/iso:c (worm)

organism-sequence


PR:Q8I4B0-2 potassium voltage-gated channel protein shk-1 isoform b (worm)
KCNA2/iso:b (worm)

organism-sequence


PR:Q8I4B0-3 potassium voltage-gated channel protein shk-1 isoform d (worm)
KCNA2/iso:d (worm)

organism-sequence


PR:Q8I4B0-4 potassium voltage-gated channel protein shk-1 isoform a (worm)
KCNA2/iso:a (worm)

organism-sequence


PR:Q8I4B0-5 potassium voltage-gated channel protein shk-1 isoform e (worm)
KCNA2/iso:e (worm)

organism-sequence


PR:Q8I4B0-6 potassium voltage-gated channel protein shk-1 isoform f (worm)
KCNA2/iso:f (worm)

organism-sequence


PR:Q8I4B0-7 potassium voltage-gated channel protein shk-1 isoform g (worm)
KCNA2/iso:g (worm)

sequence


PR:000000972 voltage-gated potassium channel subunit KCNA2 isoform 1
KCNA2/iso:1

organism-sequence


PR:P16389-1 potassium voltage-gated channel subfamily A member 2 isoform 1 (human)
hKCNA2/iso:1
Yes
organism-modification


PR:000036584 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 (human)
hKCNA2/iso:1/Phos:1
Yes
organism-modification


PR:000036587 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (human)
hKCNA2/iso:1/Phos:2
Yes
organism-sequence


PR:P63141-1 potassium voltage-gated channel subfamily A member 2 isoform 1 (mouse)
mKCNA2/iso:1

organism-modification


PR:000036585 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (mouse)
mKCNA2/iso:1/Phos:2
Yes
organism-sequence


PR:P63142-1 potassium voltage-gated channel subfamily A member 2 isoform 1 (rat)
rKCNA2/iso:1
Yes
organism-modification


PR:000036586 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (rat)
rKCNA2/iso:1/Phos:2
Yes
modification


PR:000000991 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated form
KCNA2/iso:1/PhosRes+

modification


PR:000001000 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1
KCNA2/iso:1/Phos:1

organism-modification


PR:000036584 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 (human)
hKCNA2/iso:1/Phos:1
Yes
modification


PR:000001001 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2
KCNA2/iso:1/Phos:2

organism-modification


PR:000036585 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (mouse)
mKCNA2/iso:1/Phos:2
Yes
organism-modification


PR:000036586 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (rat)
rKCNA2/iso:1/Phos:2
Yes
organism-modification


PR:000036587 voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (human)
hKCNA2/iso:1/Phos:2
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036584 hKCNA2/iso:1/Phos:1
UniProtKB:P16389-1, Tyr-132, MOD:00048		 enablesNOT GO:0005251 delayed rectifier potassium channel activity PMID:15215309
located_inGO:0005768 endosome PMID:15215309
PR:000036585 mKCNA2/iso:1/Phos:2
UniProtKB:P63141-1, Ser-440/Ser-441, MOD:00046		 located_inGO:0008076 voltage-gated potassium channel complex PMID:18056633
GO:0009986 cell surface PMID:18056633
PR:000036586 rKCNA2/iso:1/Phos:2
UniProtKB:P63142-1, Ser-440/Ser-441, MOD:00046		 located_inGO:0008076 voltage-gated potassium channel complex PMID:18056633
GO:0009986 cell surface PMID:18056633
PR:000036587 hKCNA2/iso:1/Phos:2
UniProtKB:P16389-1, Ser-440/Ser-441, MOD:00046		 located_inGO:0008076 voltage-gated potassium channel complex PMID:18056633
GO:0009986 cell surface PMID:18056633
PR:P16389-1 hKCNA2/iso:1 enablescontributes_to GO:0005251 delayed rectifier potassium channel activity PMID:1715584
located_inGO:0008076 voltage-gated potassium channel complex PMID:2251283
GO:0009986 cell surface PMID:15215309
PR:P63142-1 rKCNA2/iso:1 enablesGO:0005515 protein binding with PR:P78352 DLG4 PMID:17959782