back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - voltage-gated potassium channel subunit KCNA3
PR:000000811 - http://purl.obolibrary.org/obo/PR_000000811
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000811   
  PRO namevoltage-gated potassium channel subunit KCNA3 
  Synonyms
PRO-Short-label: EXACT:KCNA3
Gene-based: RELATED:HGK5
Other: EXACT:HLK3 | HPCN3 | MK3 | voltage-gated K(+) channel HuKIII | voltage-gated potassium channel subunit Kv1.3
  Definition"A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA3 gene or a 1:1 ortholog thereof. The Kv1.3 channel is involved in maintaining membrane potential and calcium signaling in lymphocytes and oligodendrocytes. It can coassemble with other Kv1 subunits." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000709 shaker-related voltage-gated potassium channel alpha subunit
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 3                                        
         Modification3                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
IUPHARobj:540
Back to top
Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000000811

voltage-gated potassium channel subunit KCNA3

KCNA3


"A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA3 gene or a 1:1 ortholog thereof. The Kv1.3 channel is involved in maintaining membrane potential and calcium signaling in lymphocytes and oligodendrocytes. It can coassemble with other Kv1 subunits." [PRO:CNA]


organism-gene



PR:P15384

potassium voltage-gated channel subfamily A member 3 (rat)

rKCNA3


"A voltage-gated potassium channel subunit KCNA3 that is encoded in the genome of rat." [OMA:P15384, PRO:DNx]


organism-gene



PR:P16390

potassium voltage-gated channel subfamily A member 3 (mouse)

mKCNA3


"A voltage-gated potassium channel subunit KCNA3 that is encoded in the genome of mouse." [OMA:P16390, PRO:DNx]


organism-gene



PR:P22001

potassium voltage-gated channel subfamily A member 3 (human)

hKCNA3


"A voltage-gated potassium channel subunit KCNA3 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P22001]


organism-sequence



PR:P22001-1

potassium voltage-gated channel subfamily A member 3 isoform 1 (human)

hKCNA3/iso:1


"A voltage-gated potassium channel subunit KCNA3 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036639

voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated 1 (human)

hKCNA3/iso:1/Phos:1


"A voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated 1 in human." [PMID:9989602, PRO:CL]

Yes

organism-modification



PR:000044708

voltage-gated potassium channel subunit KCNA3 isoform 1 unmodified form (human)

hKCNA3/iso:1/UnMod


"A voltage-gated potassium channel subunit KCNA3 isoform 1 unmodified form in human." [PRO:DNx]

Yes

organism-sequence



PR:P22001-4

potassium voltage-gated channel subfamily A member 3 isoform h2 (human)

hKCNA3/iso:h2


"A potassium voltage-gated channel subfamily A member 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22001-4." [PRO:DNx, UniProtKB:P22001]


organism-sequence



PR:P22001-5

potassium voltage-gated channel subfamily A member 3 isoform h3 (human)

hKCNA3/iso:h3


"A potassium voltage-gated channel subfamily A member 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22001-5." [PRO:DNx, UniProtKB:P22001]


organism-modification



PR:000065955

potassium voltage-gated channel subfamily A member 3 deaminated 1 (human)

hKCNA3/Deam:1


"A potassium voltage-gated channel subfamily A member 3 (human) that has been deaminated on the residue at the position equivalent to Asn-109 of the amino acid sequence represented by UniProtKB:P22001. UniProtKB:P22001, Asn-109, MOD:00684." [IEDB_epitope:1752498, PRO:DNx]


sequence



PR:000000973

voltage-gated potassium channel subunit KCNA3 isoform 1

KCNA3/iso:1


"A voltage-gated potassium channel subunit KCNA3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22001-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P22001-1

potassium voltage-gated channel subfamily A member 3 isoform 1 (human)

hKCNA3/iso:1


"A voltage-gated potassium channel subunit KCNA3 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036639

voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated 1 (human)

hKCNA3/iso:1/Phos:1


"A voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated 1 in human." [PMID:9989602, PRO:CL]

Yes

organism-modification



PR:000044708

voltage-gated potassium channel subunit KCNA3 isoform 1 unmodified form (human)

hKCNA3/iso:1/UnMod


"A voltage-gated potassium channel subunit KCNA3 isoform 1 unmodified form in human." [PRO:DNx]

Yes

modification



PR:000002682

voltage-gated potassium channel subunit KCNA3 isoform 1 unmodified form

KCNA3/iso:1/UnMod


"A voltage-gated potassium channel subunit KCNA3 isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]


organism-modification



PR:000044708

voltage-gated potassium channel subunit KCNA3 isoform 1 unmodified form (human)

hKCNA3/iso:1/UnMod


"A voltage-gated potassium channel subunit KCNA3 isoform 1 unmodified form in human." [PRO:DNx]

Yes

modification



PR:000003223

voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated form

KCNA3/iso:1/PhosRes+


"A voltage-gated potassium channel subunit KCNA3 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000003224

voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated 1

KCNA3/iso:1/Phos:1


"A voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated form in which the phosphorylation occurs as a result of the interaction of HIV gp160 with CD4. Probably phosphorylated by PKC." [PMID:9989602, PRO:CL]


organism-modification



PR:000036639

voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated 1 (human)

hKCNA3/iso:1/Phos:1


"A voltage-gated potassium channel subunit KCNA3 isoform 1 phosphorylated 1 in human." [PMID:9989602, PRO:CL]

Yes

Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036639 hKCNA3/iso:1/Phos:1 enablesdecreased GO:0015271 outward rectifier potassium channel activity relative to PR:000002682 KCNA3/iso:1/UnMod PMID:9989602
PR:000044708 hKCNA3/iso:1/UnMod enablesGO:0015271 outward rectifier potassium channel activity PMID:9989602
PR:P22001-1 hKCNA3/iso:1 enablesGO:0005251 delayed rectifier potassium channel activity PMID:1986382
located_inGO:0005743 mitochondrial inner membrane PMID:15632141
GO:0005886 plasma membrane PMID:15632141