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Protein Ontology report - voltage-gated potassium channel subunit KCNQ2 sequence variant M208V (human) PR:000000915 - http://purl.obolibrary.org/obo/PR_000000915        Annotations       Ontology Information Show OBO stanza / PAF / GPI   PRO ID PR:000000915      PRO name voltage-gated potassium channel subunit KCNQ2 sequence variant M208V (human)    Synonyms PRO-Short-label: EXACT: hKCNQ2/var:M208V PRO-proteoform-std: EXACT: UniProtKB:O43526, Met-208, CHEBI:30015 NARROW: UniProtKB:O43526-1, Met-208, CHEBI:30015 Other: EXACT: voltage-gated potassium channel subunit KCNQ2 sequence variant 8 (human)   Definition "A potassium voltage-gated channel subfamily KQT member 2 (human) that has a Val residue at the position equivalent to Met-208 of the amino acid sequence represented by UniProtKB:O43526-1. Example: UniProtKB:O43526-1, Met-208, CHEBI:30015." [PMID:14534157, PRO:CNA, PRO:DAN]    Comment Note: This mutation is located in the S4 transmembrane domain and causes minor effect on maximal current but clearly exhibits a faster rate of deactivation.    PRO Category organism-sequence    Parent PR:O43526 potassium voltage-gated channel subfamily KQT member 2 (human)   Taxon NCBITaxon:9606 Homo sapiens   Term Hierarchy   Visualization DAG: OLS: Back to top Related Cross References   Db identifiers UniProtKB_VAR:VAR_026988 Back to top Functional Annotation (PRO-centric view) Switch to GO Centric View    PRO Term GO Annotation Evidence PR:000000915 hKCNQ2/var:M208V Example: UniProtKB:O43526-1, Met-208, CHEBI:30015 associated_with_disease_progression DO:14264 benign neonatal seizures PMID:14534157