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Protein Ontology report - voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated form
PR:000000991 -
http://purl.obolibrary.org/obo/PR_000000991
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000991
PRO name
voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated form
Synonyms
PRO-Short-label
:
EXACT:
KCNA2/iso:1/PhosRes+
Definition
"A voltage-gated potassium channel subunit KCNA2 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
PRO Category
modification
Parent
PR:000000972
voltage-gated potassium channel subunit KCNA2 isoform 1
PR:000037070
phosphoprotein
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
3
Organism-Modification
4
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000000991
voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated form
KCNA2/iso:1/PhosRes+
"A voltage-gated potassium channel subunit KCNA2 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
modification
PR:000001000
voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1
KCNA2/iso:1/Phos:1
"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated form in which the phosphorylation occurs at the Tyr residue within the REDEGYIK sequence located adjacent to the tetramerization domain. Phosphorylation at this site promotes endocytosis and suppresses the channel activity. Example: UniProtKB:P16389-1, Tyr-132, MOD:00048." [PRO:CNA]
organism-modification
PR:000036584
voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 (human)
hKCNA2/iso:1/Phos:1
"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 in human. UniProtKB:P16389-1, Tyr-132, MOD:00048." [PMID:15215309, PRO:CNA]
Yes
modification
PR:000001001
voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2
KCNA2/iso:1/Phos:2
"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated form in which the phosphorylation occurs at the pair of Ser residues within the SSPD motif at the C terminus. Phosphorylation at this site promotes cell surface localization. Example: UniProtKB:P16389-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633]
organism-modification
PR:000036585
voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (mouse)
mKCNA2/iso:1/Phos:2
"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 in mouse. UniProtKB:P63141-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633, PRO:CNA, PRO:DAN]
Yes
organism-modification
PR:000036586
voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (rat)
rKCNA2/iso:1/Phos:2
"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 in rat. UniProtKB:P63142-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633, PRO:CNA, PRO:DAN]
Yes
organism-modification
PR:000036587
voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 (human)
hKCNA2/iso:1/Phos:2
"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 2 in human. UniProtKB:P16389-1, Ser-440/Ser-441, MOD:00046." [PMID:18056633, PRO:CNA]
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036584
hKCNA2/iso:1/Phos:1
UniProtKB:P16389-1, Tyr-132, MOD:00048
enables
NOT
GO:0005251
delayed rectifier potassium channel activity
PMID:15215309
located_in
GO:0005768
endosome
PMID:15215309
PR:000036585
mKCNA2/iso:1/Phos:2
UniProtKB:P63141-1, Ser-440/Ser-441, MOD:00046
located_in
GO:0008076
voltage-gated potassium channel complex
PMID:18056633
GO:0009986
cell surface
PMID:18056633
PR:000036586
rKCNA2/iso:1/Phos:2
UniProtKB:P63142-1, Ser-440/Ser-441, MOD:00046
located_in
GO:0008076
voltage-gated potassium channel complex
PMID:18056633
GO:0009986
cell surface
PMID:18056633
PR:000036587
hKCNA2/iso:1/Phos:2
UniProtKB:P16389-1, Ser-440/Ser-441, MOD:00046
located_in
GO:0008076
voltage-gated potassium channel complex
PMID:18056633
GO:0009986
cell surface
PMID:18056633
