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Protein Ontology report - integrin alpha-L
PR:000001011 - http://purl.obolibrary.org/obo/PR_000001011
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000001011   
  PRO nameintegrin alpha-L 
  Synonyms
PRO-Short-label: EXACT:ITGAL
Gene-based: RELATED:CD11A | Lfa-1
Other: EXACT:CD11 antigen-like family member A | CD11a | leukocyte adhesion glycoprotein LFA-1 alpha chain | leukocyte function-associated molecule 1 alpha chain | LFA-1A | ly-15 | lymphocyte antigen 15
  Definition"An integrin alpha with A domain that is a translation product of the human ITGAL gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000001005 integrin alpha with A domain
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence0                                                  Organism-Sequence 5                                        
         Modification1                                                  Organism-Modification 11                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2451
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001011
integrin alpha-L
ITGAL
"An integrin alpha with A domain that is a translation product of the human ITGAL gene or a 1:1 ortholog thereof." [PRO:CNA]

organism-gene


PR:P20701
integrin alpha-L (human)
hITGAL
"An integrin alpha-L that is encoded in the genome of human." [PRO:CNA, UniProtKB:P20701]

organism-sequence


PR:P20701-1
integrin alpha-L isoform h1 (human)
hITGAL/iso:h1
"An integrin alpha-L (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20701-1." [PRO:DNx, UniProtKB:P20701]

organism-sequence


PR:P20701-2
integrin alpha-L isoform h2 (human)
hITGAL/iso:h2
"An integrin alpha-L (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20701-2." [PRO:DNx, UniProtKB:P20701]

organism-sequence


PR:P20701-3
integrin alpha-L isoform h3 (human)
hITGAL/iso:h3
"An integrin alpha-L (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20701-3." [PRO:DNx, UniProtKB:P20701]

organism-modification


PR:000028414
integrin alpha-L, signal peptide removed form (human)
hITGAL/SigPep-
"An integrin alpha-L, signal peptide removed form in human. Example: UniProtKB:P20701-1, 26-1170." [PRO:DNx]

Yes
organism-modification


PR:000067504
integrin alpha-L methylated 1 (human)
hITGAL/Me:1
"An integrin alpha-L (human) that has been methylated on the residue at the position equivalent to Cys-717 of the amino acid sequence represented by UniProtKB:P20701-1. Example: UniProtKB:P20701-1, Cys-717, MOD:00660." [IEDB_epitope:1013227, PRO:DNx]

organism-modification


PR:000075596
integrin alpha-L deaminated 1 (human)
hITGAL/Deam:1
"An integrin alpha-L (human) that has been deaminated on the residue at the position equivalent to Gln-928 of the amino acid sequence represented by UniProtKB:P20701-1. Example: UniProtKB:P20701-1, Gln-928, MOD:00685." [IEDB_epitope:552832, PRO:DNx]

organism-modification


PR:000075999
integrin alpha-L cysteinylated 1 (human)
hITGAL/Cyst:1
"An integrin alpha-L (human) that has been cysteinylated on the residue at the position equivalent to Cys-1013 of the amino acid sequence represented by UniProtKB:P20701-1. Example: UniProtKB:P20701-1, Cys-1013, MOD:00765." [IEDB_epitope:1043252, PRO:DNx]

organism-modification


PR:000076345
integrin alpha-L deaminated 2 (human)
hITGAL/Deam:2
"An integrin alpha-L (human) that has been deaminated on the residue at the position equivalent to Gln-501 of the amino acid sequence represented by UniProtKB:P20701-1. Example: UniProtKB:P20701-1, Gln-501, MOD:00685." [IEDB_epitope:555236, PRO:DNx]

organism-modification


PR:000078384
integrin alpha-L glutathionylated 1 (human)
hITGAL/SGlt:1
"An integrin alpha-L (human) that has been glutathionylated on the residue at the position equivalent to Cys-119 of the amino acid sequence represented by UniProtKB:P20701-1. Example: UniProtKB:P20701-1, Cys-119, MOD:00234." [IEDB_epitope:422280, IEDB_epitope:422281, IEDB_epitope:422282, IEDB_epitope:422283, PRO:DNx]

organism-modification


PR:000080133
integrin alpha-L methylated 2 (human)
hITGAL/Me:2
"An integrin alpha-L (human) that has been methylated on the residue at the position equivalent to Cys-1013 of the amino acid sequence represented by UniProtKB:P20701-1. Example: UniProtKB:P20701-1, Cys-1013, MOD:00660." [IEDB_epitope:1043253, PRO:DNx]

organism-modification


PR:000081450
integrin alpha-L cysteinylated 2 (human)
hITGAL/Cyst:2
"An integrin alpha-L (human) that has been cysteinylated on the residue at the position equivalent to Cys-777 of the amino acid sequence represented by UniProtKB:P20701-1. Example: UniProtKB:P20701-1, Cys-777, MOD:00765." [IEDB_epitope:924874, PRO:DNx]

organism-modification


PR:000081773
integrin alpha-L deaminated 3 (human)
hITGAL/Deam:3
"An integrin alpha-L (human) that has been deaminated on the residue at the position equivalent to Asn-670 of the amino acid sequence represented by UniProtKB:P20701-1. Example: UniProtKB:P20701-1, Asn-670, MOD:00684." [IEDB_epitope:1366984, PRO:DNx]

organism-gene


PR:P24063
integrin alpha-L (mouse)
mITGAL
"An integrin alpha-L that is encoded in the genome of mouse." [OMA:P24063, PRO:DNx]

organism-sequence


PR:P24063-1
integrin alpha-L isoform m1 (mouse)
mITGAL/iso:m1
"An integrin alpha-L (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24063-1." [PRO:DNx, UniProtKB:P24063]

organism-sequence


PR:P24063-2
integrin alpha-L isoform m2 (mouse)
mITGAL/iso:m2
"An integrin alpha-L (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24063-2." [PRO:DNx, UniProtKB:P24063]

organism-modification


PR:000068662
integrin alpha-L deaminated 1 (mouse)
mITGAL/Deam:1
"An integrin alpha-L (mouse) that has been deaminated on the residue at the position equivalent to Gln-1073 of the amino acid sequence represented by UniProtKB:P24063-1. Example: UniProtKB:P24063-1, Gln-1073, MOD:00685." [IEDB_epitope:2136450, IEDB_epitope:2137412, PRO:DNx]

organism-modification


PR:000070115
integrin alpha-L cysteinylated 1 (mouse)
mITGAL/Cyst:1
"An integrin alpha-L (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-126 of the amino acid sequence represented by UniProtKB:P24063-1. Example: UniProtKB:P24063-1, Cys-126, MOD:00765." [IEDB_epitope:2111953, PRO:DNx]

modification


PR:000018313
integrin alpha-L, signal peptide removed form
ITGAL/SigPep-
"An integrin alpha-L that has had the signal peptide removed." [PRO:DNx]

organism-modification


PR:000028414
integrin alpha-L, signal peptide removed form (human)
hITGAL/SigPep-
"An integrin alpha-L, signal peptide removed form in human. Example: UniProtKB:P20701-1, 26-1170." [PRO:DNx]

Yes
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ITGAL forms found in complexes   

ITGAL Component
 Complexes
PR:000028414 hITGAL/SigPep- PR:000028447 LFA-1:JAM-A (human)