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Protein Ontology report - C-type lectin with multiple lectin domains
PR:000001025 - http://purl.obolibrary.org/obo/PR_000001025
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001025   
  PRO nameC-type lectin with multiple lectin domains 
  Definition"A protein that is a type I transmembrane receptor with an N-terminal cysteine-rich domain, a single Fibronectin type II (FNII) domain (Pfam:PF00040) and eight to ten copies of the Lectin C-type domain (Pfam:PF00059) (CTLDs). The presence of multiple copies of the CTLD domain is a hallmark of this class." [PMID:12223280
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene4                                                  Organism-Gene 9                                        
         Sequence0                                                  Organism-Sequence 9                                        
         Modification1                                                  Organism-Modification 19                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF002427
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000001025

C-type lectin with multiple lectin domains

NCAM1


"A protein that is a type I transmembrane receptor with an N-terminal cysteine-rich domain, a single Fibronectin type II (FNII) domain (Pfam:PF00040) and eight to ten copies of the Lectin C-type domain (Pfam:PF00059) (CTLDs). The presence of multiple copies of the CTLD domain is a hallmark of this class." [PMID:12223280]


gene



PR:000001026

lymphocyte antigen 75

LY75


"A C-type lectin with multiple lectin domains that is a translation product of the mouse LY75 gene or a 1:1 ortholog thereof. It consists of 12 extracellular domains (an N-terminal cysteine-rich domain, a fibronectin type II domain and 10 C-type carbohydrate recognition domains), a transmembrane region and a small cytoplasmic C terminus containing a single Tyr residue, but no obvious kinase domain." [PMID:9862343]


organism-gene



PR:000034294

lymphocyte antigen 75 (human)

hLY75


"A lymphocyte antigen 75 that is encoded in the genome of human." [PRO:DAN, UniProtKB:O60449]


organism-sequence



PR:O60449-1

lymphocyte antigen 75 isoform 4 (human)

hLY75/iso:4


"A lymphocyte antigen 75 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60449-1." [PRO:DAN, UniProtKB:O60449]


organism-modification



PR:000071026

lymphocyte antigen 75 isoform 4 methylated 9 (human)

hLY75/iso:4/Me:9


"A lymphocyte antigen 75 isoform 4 (human) that has been methylated on the residue at the position equivalent to Cys-110 of the amino acid sequence represented by UniProtKB:O60449-1. UniProtKB:O60449-1, Cys-110, MOD:00660." [IEDB_epitope:1003909, PRO:DNx]


organism-gene



PR:Q60767

lymphocyte antigen 75 (mouse)

mLY75


"A lymphocyte antigen 75 that is encoded in the genome of mouse." [PRO:DAN]


modification



PR:000018327

lymphocyte antigen 75, signal peptide removed form

LY75/SigPep-


"A lymphocyte antigen 75 that has had the signal peptide removed." [PRO:DNx]


gene



PR:000002972

macrophage mannose receptor 1

MRC1


"A C-type lectin with multiple lectin domains that is a translation product of the human MRC1 gene or a 1:1 ortholog thereof." [PMID:8297379, PRO:CNA]


organism-gene



PR:P22897

macrophage mannose receptor 1 (human)

hMRC1


"A macrophage mannose receptor 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P22897]


organism-sequence



PR:P22897-1

macrophage mannose receptor 1 isoform h1 (human)

hMRC1/iso:h1


"A macrophage mannose receptor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22897-1." [PRO:DNx, UniProtKB:P22897]


organism-sequence



PR:P22897-2

macrophage mannose receptor 1 isoform h2 (human)

hMRC1/iso:h2


"A macrophage mannose receptor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22897-2." [PRO:DNx, UniProtKB:P22897]


organism-modification



PR:000048415

macrophage mannose receptor 1, signal peptide removed form (human)

hMRC1/SigPep-


"A macrophage mannose receptor 1 (human) that has had the signal peptide removed. UniProtKB:P22897, 19-1456." [PRO:DNx, Reactome:R-HSA-1216515, Reactome:R-HSA-1236785, Reactome:R-HSA-1236818]


organism-modification



PR:000056200

macrophage mannose receptor 1 O-glycosylated 1 (human)

hMRC1/OGlyco:1


"A macrophage mannose receptor 1 (human) that has been O-glycosylated at the residue equivalent to Thr-1093 of the amino acid sequence represented by UniProtKB:P22897-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P22897-1, Thr-1093, MOD:00005~GNO:G29068FM." [GlyGen:P22897-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000056201

macrophage mannose receptor 1 O-glycosylated 2 (human)

hMRC1/OGlyco:2


"A macrophage mannose receptor 1 (human) that has been O-glycosylated at the residue equivalent to Thr-1093 of the amino acid sequence represented by UniProtKB:P22897-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22897-1, Thr-1093, MOD:00005~GNO:G43417UB." [GlyGen:P22897-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000056202

macrophage mannose receptor 1 O-glycosylated 3 (human)

hMRC1/OGlyco:3


"A macrophage mannose receptor 1 (human) that has been O-glycosylated at the residue equivalent to Thr-1221 of the amino acid sequence represented by UniProtKB:P22897-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P22897-1, Thr-1221, MOD:00005~GNO:G29068FM." [GlyGen:P22897-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000056203

macrophage mannose receptor 1 O-glycosylated 4 (human)

hMRC1/OGlyco:4


"A macrophage mannose receptor 1 (human) that has been O-glycosylated at the residue equivalent to Thr-1221 of the amino acid sequence represented by UniProtKB:P22897-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22897-1, Thr-1221, MOD:00005~GNO:G43417UB." [GlyGen:P22897-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000056204

macrophage mannose receptor 1 O-glycosylated 5 (human)

hMRC1/OGlyco:5


"A macrophage mannose receptor 1 (human) that has been O-glycosylated at the residue equivalent to Thr-790 of the amino acid sequence represented by UniProtKB:P22897-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22897-1, Thr-790, MOD:00005~GNO:G43417UB." [GlyGen:P22897-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000056205

macrophage mannose receptor 1 O-glycosylated 6 (human)

hMRC1/OGlyco:6


"A macrophage mannose receptor 1 (human) that has been O-glycosylated at the residue equivalent to Thr-937 of the amino acid sequence represented by UniProtKB:P22897-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P22897-1, Thr-937, MOD:00005~GNO:G29068FM." [GlyGen:P22897-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000056206

macrophage mannose receptor 1 O-glycosylated 7 (human)

hMRC1/OGlyco:7


"A macrophage mannose receptor 1 (human) that has been O-glycosylated at the residue equivalent to Thr-937 of the amino acid sequence represented by UniProtKB:P22897-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22897-1, Thr-937, MOD:00005~GNO:G43417UB." [GlyGen:P22897-1, PMID:30459171, PRO:DNx]


organism-gene



PR:Q61830

macrophage mannose receptor 1 (mouse)

mMRC1


"A macrophage mannose receptor 1 that is encoded in the genome of mouse." [OMA:Q61830, PRO:DNx]


gene



PR:000010561

C-type mannose receptor 2

MRC2


"A C-type lectin with multiple lectin domains that is a translation product of the human MRC2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q4TU93

C-type mannose receptor 2 (rat)

rMRC2


"A C-type mannose receptor 2 that is encoded in the genome of rat." [OMA:Q4TU93, PRO:DNx]


organism-gene



PR:Q64449

C-type mannose receptor 2 (mouse)

mMRC2


"A C-type mannose receptor 2 that is encoded in the genome of mouse." [OMA:Q64449, PRO:DNx]


organism-sequence



PR:Q64449-1

C-type mannose receptor 2 isoform m1 (mouse)

mMRC2/iso:m1


"A C-type mannose receptor 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q64449-1." [PRO:DNx, UniProtKB:Q64449]


organism-sequence



PR:Q64449-2

C-type mannose receptor 2 isoform m2 (mouse)

mMRC2/iso:m2


"A C-type mannose receptor 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q64449-2." [PRO:DNx, UniProtKB:Q64449]


organism-gene



PR:Q9UBG0

C-type mannose receptor 2 (human)

hMRC2


"A C-type mannose receptor 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UBG0]


organism-modification



PR:000048416

C-type mannose receptor 2, signal peptide removed form (human)

hMRC2/SigPep-


"A C-type mannose receptor 2 (human) that has had the signal peptide removed. UniProtKB:Q9UBG0, 31-1479." [PRO:DNx, Reactome:R-HSA-1216516, Reactome:R-HSA-1236847, Reactome:R-HSA-1236893]


organism-modification



PR:000069407

C-type mannose receptor 2 cysteinylated 1 (human)

hMRC2/Cyst:1


"A C-type mannose receptor 2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-1295 of the amino acid sequence represented by UniProtKB:Q9UBG0. UniProtKB:Q9UBG0, Cys-1295, MOD:00765." [IEDB_epitope:2126715, PRO:DNx]


organism-modification



PR:000070720

C-type mannose receptor 2 cysteinylated 2 (human)

hMRC2/Cyst:2


"A C-type mannose receptor 2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-1107 of the amino acid sequence represented by UniProtKB:Q9UBG0. UniProtKB:Q9UBG0, Cys-1107, MOD:00765." [IEDB_epitope:877612, PRO:DNx]


organism-modification



PR:000071404

C-type mannose receptor 2 deaminated 1 (human)

hMRC2/Deam:1


"A C-type mannose receptor 2 (human) that has been deaminated on the residue at the position equivalent to Asn-42 of the amino acid sequence represented by UniProtKB:Q9UBG0. UniProtKB:Q9UBG0, Asn-42, MOD:00684." [IEDB_epitope:1366249, PRO:DNx]


organism-modification



PR:000076598

C-type mannose receptor 2 deaminated 2 (human)

hMRC2/Deam:2


"A C-type mannose receptor 2 (human) that has been deaminated on the residue at the position equivalent to Gln-555 of the amino acid sequence represented by UniProtKB:Q9UBG0. UniProtKB:Q9UBG0, Gln-555, MOD:00685." [IEDB_epitope:1976050, PRO:DNx]


organism-modification



PR:000079559

C-type mannose receptor 2 deaminated 3 (human)

hMRC2/Deam:3


"A C-type mannose receptor 2 (human) that has been deaminated on the residue at the position equivalent to Asn-1134 of the amino acid sequence represented by UniProtKB:Q9UBG0. UniProtKB:Q9UBG0, Asn-1134, MOD:00684." [IEDB_epitope:2000535, IEDB_epitope:2143569, PRO:DNx]


gene



PR:000012813

secretory phospholipase A2 receptor

PLA2R1


"A C-type lectin with multiple lectin domains that is a translation product of the human PLA2R1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q13018

secretory phospholipase A2 receptor (human)

hPLA2R1


"A secretory phospholipase A2 receptor that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13018]


organism-sequence



PR:Q13018-1

secretory phospholipase A2 receptor isoform h1 (human)

hPLA2R1/iso:h1


"A secretory phospholipase A2 receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13018-1." [PRO:DNx, UniProtKB:Q13018]


organism-sequence



PR:Q13018-2

secretory phospholipase A2 receptor isoform h2 (human)

hPLA2R1/iso:h2


"A secretory phospholipase A2 receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13018-2." [PRO:DNx, UniProtKB:Q13018]


organism-modification



PR:000056988

secretory phospholipase A2 receptor N-glycosylated 1 (human)

hPLA2R1/NGlyco:1


"A secretory phospholipase A2 receptor (human) that has been N-glycosylated at the residue equivalent to Asn-1123 of the amino acid sequence represented by UniProtKB:Q13018-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:Q13018-1, Asn-1123, MOD:00160~GNO:G00912UN." [GlyGen:Q13018-1, PMID:23345538, PRO:DNx]


organism-modification



PR:000072492

secretory phospholipase A2 receptor deaminated 1 (human)

hPLA2R1/Deam:1


"A secretory phospholipase A2 receptor (human) that has been deaminated on the residue at the position equivalent to Asn-1035 of the amino acid sequence represented by UniProtKB:Q13018-1. Example: UniProtKB:Q13018-1, Asn-1035, MOD:00684." [IEDB_epitope:630564, PRO:DNx]


organism-gene



PR:Q62028

secretory phospholipase A2 receptor (mouse)

mPLA2R1


"A secretory phospholipase A2 receptor that is encoded in the genome of mouse." [OMA:Q62028, PRO:DNx]


organism-sequence



PR:Q62028-1

secretory phospholipase A2 receptor isoform m1 (mouse)

mPLA2R1/iso:m1


"A secretory phospholipase A2 receptor (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62028-1." [PRO:DNx, UniProtKB:Q62028]


organism-sequence



PR:Q62028-2

secretory phospholipase A2 receptor isoform m2 (mouse)

mPLA2R1/iso:m2


"A secretory phospholipase A2 receptor (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62028-2." [PRO:DNx, UniProtKB:Q62028]


organism-modification



PR:000085759

secretory phospholipase A2 receptor, signal peptide removed form (mouse)

mPLA2R1/SigPep-


"A secretory phospholipase A2 receptor (mouse) that has had the signal peptide removed. UniProtKB:Q62028, 27-1487." [PRO:DAN, UniProtKB:Q62028]


organism-modification



PR:000085751

soluble secretory phospholipase A2 receptor (mouse)

mPLA2R1/soluble


"A secretory phospholipase A2 receptor, signal peptide removed form (mouse) that corresponds to the N-terminal portion after proteolytic cleavage. UniProtKB:Q62028, 27-?." [PRO:DAN, UniProtKB:Q62028]