back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - ezrin isoform 1 phosphorylated form
PR:000001033 - http://purl.obolibrary.org/obo/PR_000001033
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001033   
  PRO nameezrin isoform 1 phosphorylated form 
  Synonyms
PRO-Short-label: EXACT:EZR/iso:1/PhosRes+
  Definition"An ezrin isoform 1 that includes at least one phosphorylated residue." [PRO:CNA] 
  PRO Categorymodification 
  ParentPR:000001032 ezrin isoform 1
PR:000037070 phosphoprotein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification7                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000001033
ezrin isoform 1 phosphorylated form
EZR/iso:1/PhosRes+
"An ezrin isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]

modification


PR:000001034
ezrin isoform 1 phosphorylated 1
EZR/iso:1/Phos:1
"An ezrin isoform 1 phosphorylated form in which the phosphorylation occurs upon EGF stimulation. Example: UniProtKB:P15311-1, Tyr-146/Tyr-354, MOD:00048." [PMID:1382070]

organism-modification


PR:000036588
ezrin isoform 1 phosphorylated 1 (human)
hEZR/iso:1/Phos:1
"An ezrin isoform 1 phosphorylated 1 in human. UniProtKB:P15311-1, Tyr-146/Tyr-354, MOD:00048." [PMID:1382070, PRO:CNA]

modification


PR:000001035
ezrin isoform 1 phosphorylated 2
EZR/iso:1/Phos:2
"An ezrin isoform 1 phosphorylated form in which the phosphorylation occurs by the action of protein kinase A (PKA). Example: UniProtKB:P15311-1, Ser-66, MOD:00046." [PhosphoSitePlus:28933, PMID:12840026, PMID:16438931]

organism-modification


PR:000036589
ezrin isoform 1 phosphorylated 2 (human)
hEZR/iso:1/Phos:2
"An ezrin isoform 1 phosphorylated 2 in human. UniProtKB:P15311-1, Ser-66, MOD:00046." [PMID:12840026, PMID:16438931, PRO:CNA]
Yes
modification


PR:000001038
ezrin isoform 1 phosphorylated 3
EZR/iso:1/Phos:3
"An ezrin isoform 1 phosphorylated form in which the phosphorylation occurs at the first Tyr residue within the ITAM-like motif EYLKIAQDLEMYGINYFEI. Example: UniProtKB:P15311-1, Tyr-191, MOD:00048." [PMID:15647376, PMID:9052872]

organism-modification


PR:000036590
ezrin isoform 1 phosphorylated 3 (human)
hEZR/iso:1/Phos:3
"An ezrin isoform 1 phosphorylated 3 in human. UniProtKB:P15311-1, Tyr-191, MOD:00048." [PMID:15647376, PRO:CNA]
Yes
modification


PR:000001039
ezrin isoform 1 phosphorylated 4
EZR/iso:1/Phos:4
"An ezrin isoform 1 phosphorylated form in which the phosphorylation occurs both in a Tyr residue within the FERM central domain, and the first Tyr residue within the ITAM-like motif EYLKIAQDLEMYGINYFEI. Example: UniProtKB:P15311-1, Tyr-146/Tyr-191, MOD:00048|Thr-567, MOD:00047." [PMID:15647376]

organism-modification


PR:000036591
ezrin isoform 1 phosphorylated 4 (human)
hEZR/iso:1/Phos:4
"An ezrin isoform 1 phosphorylated 4 in human. UniProtKB:P15311-1, Tyr-146/Tyr-191, MOD:00048|Thr-567, MOD:00047." [PMID:15647376, PRO:CNA]

modification


PR:000001040
ezrin isoform 1 phosphorylated 5
EZR/iso:1/Phos:5
"An ezrin isoform 1 phosphorylated form in which the phosphorylation occurs at a Thr residue located within the C-terminal domain. Example: UniProtKB:P15311-1, Thr-567, MOD:00047." [PMID:16144865]

organism-modification


PR:000036592
ezrin isoform 1 phosphorylated 5 (human)
hEZR/iso:1/Phos:5
"An ezrin isoform 1 phosphorylated 5 in human. UniProtKB:P15311-1, Thr-567, MOD:00047." [PMID:16144865, PMID:18025306, PRO:AL, PRO:CNA]
Yes
organism-modification


PR:000044790
ezrin isoform 1 phosphorylated 5 (mouse)
mEZR/iso:1/Phos:5
"An ezrin isoform 1 phosphorylated 5 in mouse. UniProtKB:P26040-1, Thr-567, MOD:00047." [PRO:DAN]

modification


PR:000003042
ezrin isoform 1 phosphorylated 6
EZR/iso:1/Phos:6
"An ezrin isoform 1 phosphorylated form in which the phosphorylation occurs at either the C-terminal Thr (Thr-567 in human), through kinases such as Rho-kinase, or the N-terminal tyrosine residue (Tyr-354 in human). Example: UniProtKB:P15311-1, Tyr-354, MOD:00048|Thr-567, MOD:00047." [PMID:18852256, PRO:AL]

organism-modification


PR:000036625
ezrin isoform 1 phosphorylated 6 (human)
hEZR/iso:1/Phos:6
"An ezrin isoform 1 phosphorylated 6 in human. UniProtKB:P15311-1, Tyr-354, MOD:00048|Thr-567, MOD:00047." [PMID:18852256, PRO:AL]
Yes
Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036589 hEZR/iso:1/Phos:2
UniProtKB:P15311-1, Ser-66, MOD:00046		 enablesGO:0005515 protein binding with PR:000002696 WWOX/iso:1/UnMod PMID:16438931
PR:000036590 hEZR/iso:1/Phos:3
UniProtKB:P15311-1, Tyr-191, MOD:00048		 enablesGO:0005515 protein binding with PR:P00523-1 PMID:15647376
PR:000036592 hEZR/iso:1/Phos:5
UniProtKB:P15311-1, Thr-567, MOD:00047		 acts_upstream_of_or_withinGO:0001771 immunological synapse formation PMID:18025306
GO:0051279 regulation of release of sequestered calcium ion into cytosol PMID:18025306
enablesGO:0005515 protein binding with PR:P43403 70 kDa zeta-chain associated protein (human) PMID:18025306
located_inGO:0001772 immunological synapse PMID:18025306
GO:0045177 apical part of cell PMID:16144865
PR:000036625 hEZR/iso:1/Phos:6
UniProtKB:P15311-1, Tyr-354, MOD:00048|Thr-567, MOD:00047		 enablesGO:0003779 actin binding PMID:18852256
located_inGO:0002102 podosome PMID:18852256
GO:0005886 plasma membrane PMID:18852256