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Protein Ontology report - Na(+)/H(+) exchange regulatory cofactor with ERM-binding domain
PR:000001043 - http://purl.obolibrary.org/obo/PR_000001043
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001043   
  PRO nameNa(+)/H(+) exchange regulatory cofactor with ERM-binding domain 
  Synonyms
Other: RELATED:NHERF
  Definition"A protein that consists of two copies of the PDZ domain (Pfam:PF00595) and a copy of the EBP50, C-terminal (Pfam:PF09007) domain." [PMID:15905209] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene2                                                  Organism-Gene 7                                        
         Sequence3                                                  Organism-Sequence 10                                        
         Modification2                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF037866
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000001043 Na(+)/H(+) exchange regulatory cofactor with ERM-binding domain
NHERF1/iso:1

gene


PR:000001041 Na(+)/H(+) exchange regulatory cofactor NHE-RF1
NHERF1

organism-gene


PR:O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (human)
hNHERF1

organism-sequence


PR:O14745-1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 (human)
hNHERF1/iso:1

organism-sequence


PR:O14745-2 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform h2 (human)
hNHERF1/iso:h2

organism-modification


PR:000084870 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 methylated 1 (human)
hNHERF1/Me:1

organism-gene


PR:P70441 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (mouse)
mNHERF1

organism-sequence


PR:P70441-1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 (mouse)
mNHERF1/iso:1
Yes
organism-sequence


PR:P70441-2 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 2 (mouse)
mNHERF1/iso:2

organism-modification


PR:000046189 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 phosphorylated 1 (mouse)
mNHERF1/Phos:1

organism-gene


PR:Q5ZM14 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (chicken)
chick-NHERF1

organism-gene


PR:Q9JJ19 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (rat)
rNHERF1

organism-sequence


PR:Q9JJ19-1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 (rat)
rNHERF1/iso:1

sequence


PR:000001042 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1
NHERF1/iso:1

organism-sequence


PR:O14745-1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 (human)
hNHERF1/iso:1

organism-sequence


PR:P70441-1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 (mouse)
mNHERF1/iso:1
Yes
organism-sequence


PR:Q9JJ19-1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1 (rat)
rNHERF1/iso:1

modification


PR:000026596 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1, initiator methionine removed form
NHERF1/iso:1/InitMet-

sequence


PR:000001058 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 2
NHERF1/iso:2

organism-sequence


PR:P70441-2 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 2 (mouse)
mNHERF1/iso:2

modification


PR:000018331 Na(+)/H(+) exchange regulatory cofactor NHE-RF1, initiator methionine removed form
NHERF1/InitMet-

modification


PR:000026596 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform 1, initiator methionine removed form
NHERF1/iso:1/InitMet-

gene


PR:000015215 Na(+)/H(+) exchange regulatory cofactor NHE-RF2
NHERF2

organism-gene


PR:Q15599 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (human)
hNHERF2

organism-sequence


PR:Q15599-1 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform 1 (human)
hNHERF2/iso:1

organism-sequence


PR:Q15599-2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform h2 (human)
hNHERF2/iso:h2

organism-sequence


PR:Q15599-3 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform h3 (human)
hNHERF2/iso:h3

organism-modification


PR:000071702 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 deaminated 1 (human)
hNHERF2/Deam:1

organism-modification


PR:000082185 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 deaminated 2 (human)
hNHERF2/Deam:2

organism-gene


PR:Q920G2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (rat)
rNHERF2

organism-gene


PR:Q9JHL1 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (mouse)
mNHERF2

organism-sequence


PR:Q9JHL1-1 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform 1 (mouse)
mNHERF2/iso:1

organism-sequence


PR:Q9JHL1-2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform m2 (mouse)
mNHERF2/iso:m2

sequence


PR:000040655 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform 1
NHERF2/iso:1

organism-sequence


PR:Q15599-1 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform 1 (human)
hNHERF2/iso:1

organism-sequence


PR:Q9JHL1-1 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform 1 (mouse)
mNHERF2/iso:1

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P70441-1 mNHERF1/iso:1 enablesGO:0051219 phosphoprotein binding with PR:000044790 mEZR/iso:1/Phos:5 PMID:15591354
located_inGO:0031526 brush border membrane PMID:15591354