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Protein Ontology report - transient receptor potential cation channel TRPC with PDZ-binding motif
PR:000001074 - http://purl.obolibrary.org/obo/PR_000001074
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001074   
  PRO nametransient receptor potential cation channel TRPC with PDZ-binding motif 
  Definition"A transient receptor potential cation channel TRPC with a carboxyl-terminal PDZ-binding motif (VTTRL). They form homomeric or heteromeric (with TRPC1) cation channels that are activated following stimulation of Gq-coupled receptors." [PMID:16382100, PMID:16460286, PMID:17579562, PRO:WCB] 
  PRO Categoryfamily 
  ParentPR:000000680 transient receptor potential cation channel TRPC
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene1                                                  Organism-Gene 3                                        
         Sequence4                                                  Organism-Sequence 11                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000001074 transient receptor potential cation channel TRPC with PDZ-binding motif
TRPV4/iso:E

gene


PR:000001075 short transient receptor potential cation channel TRPC4
TRPC4

organism-gene


PR:O35119 short transient receptor potential channel 4 (rat)
rTRPC4

organism-sequence


PR:O35119-1 short transient receptor potential channel 4 isoform alpha (rat)
rTRPC4/iso:Alpha

organism-sequence


PR:O35119-2 short transient receptor potential channel 4 isoform beta (rat)
rTRPC4/iso:Beta

organism-gene


PR:Q9QUQ5 short transient receptor potential channel 4 (mouse)
mTRPC4
Yes
organism-sequence


PR:Q9QUQ5-1 short transient receptor potential channel 4 isoform alpha (mouse)
mTRPC4/iso:Alpha
Yes
organism-sequence


PR:Q9QUQ5-2 short transient receptor potential channel 4 isoform beta (mouse)
mTRPC4/iso:Beta

organism-gene


PR:Q9UBN4 short transient receptor potential channel 4 (human)
hTRPC4

organism-sequence


PR:Q9UBN4-1 short transient receptor potential channel 4 isoform alpha (human)
hTRPC4/iso:Alpha
Yes
organism-sequence


PR:Q9UBN4-2 short transient receptor potential channel 4 isoform beta (human)
hTRPC4/iso:Beta
Yes
organism-sequence


PR:Q9UBN4-3 short transient receptor potential channel 4 isoform delta (human)
hTRPC4/iso:Delta

organism-sequence


PR:Q9UBN4-4 short transient receptor potential channel 4 isoform gamma (human)
hTRPC4/iso:Gamma

organism-sequence


PR:Q9UBN4-5 short transient receptor potential channel 4 isoform Epsilon (human)
hTRPC4/iso:Epsilon

organism-sequence


PR:Q9UBN4-6 short transient receptor potential channel 4 isoform Zeta (human)
hTRPC4/iso:Zeta

organism-sequence


PR:Q9UBN4-7 short transient receptor potential channel 4 isoform Eta (human)
hTRPC4/iso:Eta

sequence


PR:000001076 short transient receptor potential cation channel TRPC4 isoform 1
TRPC4/iso:1

organism-sequence


PR:O35119-1 short transient receptor potential channel 4 isoform alpha (rat)
rTRPC4/iso:Alpha

organism-sequence


PR:Q9QUQ5-1 short transient receptor potential channel 4 isoform alpha (mouse)
mTRPC4/iso:Alpha
Yes
organism-sequence


PR:Q9UBN4-1 short transient receptor potential channel 4 isoform alpha (human)
hTRPC4/iso:Alpha
Yes
sequence


PR:000001077 short transient receptor potential cation channel TRPC4 isoform 2
TRPC4/iso:2

organism-sequence


PR:O35119-2 short transient receptor potential channel 4 isoform beta (rat)
rTRPC4/iso:Beta

organism-sequence


PR:Q9QUQ5-2 short transient receptor potential channel 4 isoform beta (mouse)
mTRPC4/iso:Beta

organism-sequence


PR:Q9UBN4-2 short transient receptor potential channel 4 isoform beta (human)
hTRPC4/iso:Beta
Yes
sequence


PR:000001078 short transient receptor potential cation channel TRPC4 isoform 3
TRPC4/iso:3

organism-sequence


PR:Q9UBN4-3 short transient receptor potential channel 4 isoform delta (human)
hTRPC4/iso:Delta

sequence


PR:000001079 short transient receptor potential cation channel TRPC4 isoform 4
TRPC4/iso:4

organism-sequence


PR:Q9UBN4-4 short transient receptor potential channel 4 isoform gamma (human)
hTRPC4/iso:Gamma

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9QUQ5 mTRPC4 acts_upstream_of_or_withinGO:0014051 gamma-aminobutyric acid secretion PMID:14668438
located_inGO:0005901 caveola PMID:11897792
PR:Q9QUQ5-1 mTRPC4/iso:Alpha enablesGO:0015279 store-operated calcium channel activity MGI_ref:3525810; PMID:15044151
located_inGO:0005886 plasma membrane MGI_ref:3525810; PMID:15044151
PR:Q9UBN4-1 hTRPC4/iso:Alpha enablescontributes_to GO:0015279 store-operated calcium channel activity PMID:11713258
GO:0042802 identical protein binding PMID:11713258
located_inGO:0005886 plasma membrane PMID:11713258
PR:Q9UBN4-2 hTRPC4/iso:Beta enablescontributes_to GO:0015279 store-operated calcium channel activity PMID:11713258
GO:0042802 identical protein binding PMID:11713258
located_inGO:0005886 plasma membrane PMID:11713258