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Protein Ontology report - T-cell surface glycoprotein CD8 alpha chain
PR:000001084 - http://purl.obolibrary.org/obo/PR_000001084
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000001084   
  PRO nameT-cell surface glycoprotein CD8 alpha chain 
  Synonyms
PRO-Short-label: EXACT:CD8A
Gene-based: RELATED:Lyt-2 | Lyt2 | MAL
Other: EXACT:CD8a | T-cell surface glycoprotein Lyt-2 | T-lymphocyte differentiation antigen T8/Leu-2
  Definition"A protein that is a translation product of the human CD8A gene or a 1:1 ortholog thereof. CD8 is a transmembrane that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain." [PMID:11114424, PRO:CNA, Wikipedia:CD8] 
  CommentRequested by=CL. 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence2                                                  Organism-Sequence 4                                        
         Modification3                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001084 T-cell surface glycoprotein CD8 alpha chain
CD8A

organism-gene


PR:F1NXT4 uncharacterized protein, CD8A translation product (chicken)
chick-CD8A

organism-gene


PR:P01731 T-cell surface glycoprotein CD8 alpha chain (mouse)
mCD8A

organism-sequence


PR:P01731-1 T-cell surface glycoprotein CD8 alpha chain isoform m1 (mouse)
mCD8A/iso:m1

organism-gene


PR:P01732 T-cell surface glycoprotein CD8 alpha chain (human)
hCD8A

organism-sequence


PR:P01732-1 T-cell surface glycoprotein CD8 alpha chain isoform 1 (human)
hCD8A/iso:1

organism-sequence


PR:P01732-2 T-cell surface glycoprotein CD8 alpha chain isoform 2 (human)
hCD8A/iso:2

organism-sequence


PR:P01732-3 T-cell surface glycoprotein CD8 alpha chain isoform h3 (human)
hCD8A/iso:h3

organism-modification


PR:000046653 T-cell surface glycoprotein CD8 alpha chain, signal peptide removed form (human)
hCD8A/SigPep-

organism-modification


PR:000052042 T-cell surface glycoprotein CD8 alpha chain O-glycosylated 1 (human)
hCD8A/OGlyco:1

organism-modification


PR:000052043 T-cell surface glycoprotein CD8 alpha chain O-glycosylated 2 (human)
hCD8A/OGlyco:2

organism-gene


PR:P07725 T-cell surface glycoprotein CD8 alpha chain (rat)
rCD8A

sequence


PR:000025403 T-cell surface glycoprotein CD8 alpha chain isoform 1
CD8A/iso:1

organism-sequence


PR:P01732-1 T-cell surface glycoprotein CD8 alpha chain isoform 1 (human)
hCD8A/iso:1

modification


PR:000025406 T-cell surface glycoprotein CD8 alpha chain isoform 1, signal peptide removed form
CD8A/iso:1/SigPep-

modification


PR:000025408 T-cell surface glycoprotein CD8 alpha chain isoform 1, signal peptide removed glycosylated form
CD8A/iso:1/SigPep-/GlycoRes+

Yes
sequence


PR:000025404 T-cell surface glycoprotein CD8 alpha chain isoform 2
CD8A/iso:2

organism-sequence


PR:P01732-2 T-cell surface glycoprotein CD8 alpha chain isoform 2 (human)
hCD8A/iso:2

modification


PR:000018335 T-cell surface glycoprotein CD8 alpha chain, signal peptide removed form
CD8A/SigPep-

modification


PR:000025406 T-cell surface glycoprotein CD8 alpha chain isoform 1, signal peptide removed form
CD8A/iso:1/SigPep-

modification


PR:000025408 T-cell surface glycoprotein CD8 alpha chain isoform 1, signal peptide removed glycosylated form
CD8A/iso:1/SigPep-/GlycoRes+

Yes
organism-modification


PR:000046653 T-cell surface glycoprotein CD8 alpha chain, signal peptide removed form (human)
hCD8A/SigPep-

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CD8A forms found in complexes   

CD8A Component
 Complexes
PR:000025408 CD8A/iso:1/SigPep-/GlycoRes+ PR:000025402 T cell receptor co-receptor CD8