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Protein Ontology report - C-X-C chemokine receptor type 4
PR:000001208 - http://purl.obolibrary.org/obo/PR_000001208
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001208   
  PRO nameC-X-C chemokine receptor type 4 
  Synonyms
PRO-Short-label: EXACT:CXCR4
Gene-based: RELATED:Cmkar4 | Sdf1r
Other: EXACT:CD184 | chemokine receptor CXCR4 | CXC-R4 | CXCR-4 | FB22 | fusin | HM89 | LCR1 | LESTR | leukocyte-derived seven transmembrane domain receptor | NPYRL | PB-CKR | pre-B-cell-derived chemokine receptor | SDF-1 receptor | stromal cell-derived factor 1 receptor
  Definition"A chemokine receptor that is a translation product of the human CXCR4 gene or a 1:1 ortholog thereof. The preferred ligand is CXCL12." [PMID:12037138, PRO:WCB] 
  CommentRequested by=CL. 
  PRO Categorygene 
  ParentPR:000001128 chemokine receptor
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF501021;IUPHARobj:71
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001208
C-X-C chemokine receptor type 4
CXCR4
"A chemokine receptor that is a translation product of the human CXCR4 gene or a 1:1 ortholog thereof. The preferred ligand is CXCL12." [PMID:12037138, PRO:WCB]

organism-gene


PR:O08565
C-X-C chemokine receptor type 4 (rat)
rCXCR4
"A C-X-C chemokine receptor type 4 that is encoded in the genome of rat." [OMA:O08565, PRO:DNx]

organism-gene


PR:P61073
C-X-C chemokine receptor type 4 (human)
hCXCR4
"A C-X-C chemokine receptor type 4 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P61073]

organism-sequence


PR:P61073-1
C-X-C chemokine receptor type 4 isoform h1 (human)
hCXCR4/iso:h1
"A C-X-C chemokine receptor type 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61073-1." [PRO:DNx, UniProtKB:P61073]

organism-sequence


PR:P61073-2
C-X-C chemokine receptor type 4 isoform h2 (human)
hCXCR4/iso:h2
"A C-X-C chemokine receptor type 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61073-2." [PRO:DNx, UniProtKB:P61073]

organism-modification


PR:000068357
C-X-C chemokine receptor type 4 phosphorylated 1 (human)
hCXCR4/Phos:1
"A C-X-C chemokine receptor type 4 (human) that has been phosphorylated on the residue at the position equivalent to Ser-324 of the amino acid sequence represented by UniProtKB:P61073. UniProtKB:P61073, Ser-324, MOD:00046." [IEDB_epitope:1588505, PRO:DNx]

organism-modification


PR:000077067
C-X-C chemokine receptor type 4 phosphorylated 2 (human)
hCXCR4/Phos:2
"A C-X-C chemokine receptor type 4 (human) that has been phosphorylated on the residue at the position equivalent to Ser-339 of the amino acid sequence represented by UniProtKB:P61073. UniProtKB:P61073, Ser-339, MOD:00046." [IEDB_epitope:1577614, IEDB_epitope:1587264, IEDB_epitope:2146624, PRO:DNx]

organism-modification


PR:000082633
C-X-C chemokine receptor type 4 phosphorylated 3 (human)
hCXCR4/Phos:3
"A C-X-C chemokine receptor type 4 (human) that has been phosphorylated on the residue at the position equivalent to Ser-325 of the amino acid sequence represented by UniProtKB:P61073. UniProtKB:P61073, Ser-325, MOD:00046." [IEDB_epitope:1572396, IEDB_epitope:1587262, IEDB_epitope:1588506, IEDB_epitope:2146754, IEDB_epitope:2146755, IEDB_epitope:2146756, PRO:DNx]

organism-gene


PR:P70658
C-X-C chemokine receptor type 4 (mouse)
mCXCR4
"A C-X-C chemokine receptor type 4 that is encoded in the genome of mouse." [OMA:P70658, PRO:DNx]

organism-sequence


PR:P70658-1
C-X-C chemokine receptor type 4 isoform mCXCR4-B (mouse)
mCXCR4/iso:mCXCR4-B
"A C-X-C chemokine receptor type 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70658-1." [PRO:DNx, UniProtKB:P70658]

organism-sequence


PR:P70658-2
C-X-C chemokine receptor type 4 isoform mCXCR4-A (mouse)
mCXCR4/iso:mCXCR4-A
"A C-X-C chemokine receptor type 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70658-2." [PRO:DNx, UniProtKB:P70658]