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Protein Ontology report - class 2 cytokine, IL-10 type
PR:000001335 - http://purl.obolibrary.org/obo/PR_000001335
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001335   
  PRO nameclass 2 cytokine, IL-10 type 
  Definition"A protein with a core domain architecture consisting of an N-terminal Interleukin 10 (Pfam:PF00726) domain." [PRO:CNA] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family3                                                  Organism-Family 0                                        
         Gene8                                                  Organism-Gene 16                                        
         Sequence4                                                  Organism-Sequence 15                                        
         Modification4                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF003542
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000001335 class 2 cytokine, IL-10 type
SLC44A1

gene


PR:000001471 interleukin-10
IL10

organism-gene


PR:P18893 interleukin-10 (mouse)
mIL10

organism-sequence


PR:P18893-1 interleukin-10 isoform 1 (mouse)
mIL10/iso:1

organism-gene


PR:P22301 interleukin-10 (human)
hIL10

organism-sequence


PR:P22301-1 interleukin-10 isoform 1 (human)
hIL10/iso:1

organism-modification


PR:000063204 interleukin-10, signal peptide removed form (human)
hIL10/SigPep-

organism-gene


PR:P29456 interleukin-10 (rat)
rIL10

organism-sequence


PR:P29456-1 interleukin-10 isoform 1 (rat)
rIL10/iso:1

organism-gene


PR:Q6A2H4 interleukin-10 (chicken)
chick-IL10

sequence


PR:000039066 interleukin-10 isoform 1
IL10/iso:1

organism-sequence


PR:P18893-1 interleukin-10 isoform 1 (mouse)
mIL10/iso:1

organism-sequence


PR:P22301-1 interleukin-10 isoform 1 (human)
hIL10/iso:1

organism-sequence


PR:P29456-1 interleukin-10 isoform 1 (rat)
rIL10/iso:1

modification


PR:000018500 interleukin-10, signal peptide removed form
IL10/SigPep-

organism-modification


PR:000063204 interleukin-10, signal peptide removed form (human)
hIL10/SigPep-

gene


PR:000001472 interleukin-19
IL19

organism-gene


PR:Q8CJ70 interleukin-19 (mouse)
mIL19

organism-gene


PR:Q9UHD0 interleukin-19 (human)
hIL19

organism-sequence


PR:Q9UHD0-1 interleukin-19 isoform h1 (human)
hIL19/iso:h1

organism-sequence


PR:Q9UHD0-2 interleukin-19 isoform h2 (human)
hIL19/iso:h2

organism-sequence


PR:Q9UHD0-3 interleukin-19 isoform h3 (human)
hIL19/iso:h3

organism-modification


PR:000047998 interleukin-19, signal peptide removed form (human)
hIL19/SigPep-

organism-modification


PR:000084574 interleukin-19 citrullinated 1 (human)
hIL19/Cit:1

modification


PR:000018502 interleukin-19, signal peptide removed form
IL19/SigPep-

organism-modification


PR:000047998 interleukin-19, signal peptide removed form (human)
hIL19/SigPep-

gene


PR:000001473 interleukin-20
IL20

organism-gene


PR:Q9JKV9 interleukin-20 (mouse)
mIL20

organism-sequence


PR:Q9JKV9-1 interleukin-20 isoform 1 (mouse)
mIL20/iso:1

organism-gene


PR:Q9NYY1 interleukin-20 (human)
hIL20

organism-sequence


PR:Q9NYY1-1 interleukin-20 isoform 1 (human)
hIL20/iso:1

organism-sequence


PR:Q9NYY1-2 interleukin-20 isoform h2 (human)
hIL20/iso:h2

organism-modification


PR:000048004 interleukin-20, signal peptide removed form (human)
hIL20/SigPep-

sequence


PR:000043670 interleukin-20 isoform 1
IL20/iso:1

organism-sequence


PR:Q9JKV9-1 interleukin-20 isoform 1 (mouse)
mIL20/iso:1

organism-sequence


PR:Q9NYY1-1 interleukin-20 isoform 1 (human)
hIL20/iso:1

modification


PR:000018504 interleukin-20, signal peptide removed form
IL20/SigPep-

organism-modification


PR:000048004 interleukin-20, signal peptide removed form (human)
hIL20/SigPep-

gene


PR:000001474 interleukin-24
IL24

organism-gene


PR:Q13007 interleukin-24 (human)
hIL24

organism-sequence


PR:Q13007-1 interleukin-24 isoform h1 (human)
hIL24/iso:h1

organism-sequence


PR:Q13007-2 interleukin-24 isoform h2 (human)
hIL24/iso:h2

organism-sequence


PR:Q13007-3 interleukin-24 isoform h3 (human)
hIL24/iso:h3

organism-sequence


PR:Q13007-4 interleukin-24 isoform h4 (human)
hIL24/iso:h4

organism-modification


PR:000048011 interleukin-24, signal peptide removed form (human)
hIL24/SigPep-

organism-gene


PR:Q925S4 interleukin-24 (mouse)
mIL24

organism-sequence


PR:A3QQZ3 interleukin-24 isoform 2 (mouse)
mIL24/iso:2
Yes
organism-sequence


PR:Q925S4-1 interleukin-24 isoform 1 (mouse)
mIL24/iso:1
Yes
organism-gene


PR:Q9JI24 interleukin-24 (rat)
rIL24

sequence


PR:000035507 interleukin-24 isoform 1
IL24/iso:1

organism-sequence


PR:Q925S4-1 interleukin-24 isoform 1 (mouse)
mIL24/iso:1
Yes
sequence


PR:000035509 interleukin-24 isoform 2
IL24/iso:2
Yes
organism-sequence


PR:A3QQZ3 interleukin-24 isoform 2 (mouse)
mIL24/iso:2
Yes
modification


PR:000018506 interleukin-24, signal peptide removed form
IL24/SigPep-

organism-modification


PR:000048011 interleukin-24, signal peptide removed form (human)
hIL24/SigPep-

gene


PR:000001475 interleukin-26
IL26

organism-gene


PR:Q9NPH9 interleukin-26 (human)
hIL26

organism-modification


PR:000063437 interleukin-26, signal peptide removed form (human)
hIL26/SigPep-

family


PR:000028205 type III interferon
cdc8

family


PR:000001362 interferon lambda
IFNGR1

gene


PR:000001469 interleukin-28A
IFNL2

organism-gene


PR:Q8IZJ0 interferon lambda-2 (human)
hIFNL2

organism-modification


PR:000047967 interferon lambda-2, signal peptide removed form (human)
hIFNL2/SigPep-

gene


PR:000001470 interleukin-28B
IFNL3

organism-gene


PR:B4ER10 interferon lambda-3 (chicken)
chick-IFNL3

organism-gene


PR:Q8IZI9 interferon lambda-3 (human)
hIFNL3

organism-modification


PR:000047968 interferon lambda-3, signal peptide removed form (human)
hIFNL3/SigPep-

gene


PR:000001476 interleukin-29
IFNL1

organism-gene


PR:Q8IU54 interferon lambda-1 (human)
hIFNL1

organism-modification


PR:000047966 interferon lambda-1, signal peptide removed form (human)
hIFNL1/SigPep-

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035509 IL24/iso:2 acts_upstream_of_or_withinGO:0010951 negative regulation of endopeptidase activity MGI_ref:3821693; PMID:18708357
GO:0043066 negative regulation of apoptotic process MGI_ref:3821693; PMID:18708357
PR:A3QQZ3 mIL24/iso:2 acts_upstream_of_or_withinGO:0010951 negative regulation of endopeptidase activity MGI_ref:3821693; PMID:18708357
GO:0043066 negative regulation of apoptotic process MGI_ref:3821693; PMID:18708357
located_inGO:0005783 endoplasmic reticulum MGI_ref:3821693; PMID:18708357
PR:Q925S4-1 mIL24/iso:1 acts_upstream_of_or_withinGO:0008285 negative regulation of cell population proliferation MGI_ref:3821693; PMID:18708357
enablesGO:0005515 protein binding with PR:A3QQZ3 FISP cytokine variant FISP-sp (mouse) MGI_ref:3821693; PMID:18708357
located_inGO:0005576 extracellular region MGI_ref:3821693; PMID:18708357