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Protein Ontology report - immunoglobulin gamma Fc receptor II/III/IV
PR:000001355 - http://purl.obolibrary.org/obo/PR_000001355
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001355   
  PRO nameimmunoglobulin gamma Fc receptor II/III/IV 
  Definition"A protein with a core domain architecture consisting of an extracellular domain containing two copies of the Immunoglobulin domain (Pfam:PF00047), followed by a single-pass transmembrane region and a small intracellular domain. The active protein is a low affinity receptor for immunoglobulin gamma chain Fc region. Human II-a, II-b, and II-c represent a recent gene expansion and are equally related to mouse II, III, and IV. Human III-A and III-B are closely related and closer to mouse IV than to mouse III." [PRO:WCB] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene8                                                  Organism-Gene 13                                        
         Sequence0                                                  Organism-Sequence 25                                        
         Modification3                                                  Organism-Modification 8                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF001980
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000001355

immunoglobulin gamma Fc receptor II/III/IV

CSF2RA


"A protein with a core domain architecture consisting of an extracellular domain containing two copies of the Immunoglobulin domain (Pfam:PF00047), followed by a single-pass transmembrane region and a small intracellular domain. The active protein is a low affinity receptor for immunoglobulin gamma chain Fc region. Human II-a, II-b, and II-c represent a recent gene expansion and are equally related to mouse II, III, and IV. Human III-A and III-B are closely related and closer to mouse IV than to mouse III." [PRO:WCB]


gene



PR:000001479

low affinity immunoglobulin gamma Fc region receptor II

Fcgr2


"An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the mouse Fcgr2 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P08101

low affinity immunoglobulin gamma Fc region receptor II (mouse)

mFcgr2


"A low affinity immunoglobulin gamma Fc region receptor II that is encoded in the genome of mouse." [PRO:CNA, UniProtKB:P08101]


organism-sequence



PR:P08101-1

low affinity immunoglobulin gamma Fc region receptor II isoform mIIB1 (mouse)

mFcgr2/iso:mIIB1


"A low affinity immunoglobulin gamma Fc region receptor II (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08101-1." [PRO:DNx, UniProtKB:P08101]


organism-sequence



PR:P08101-2

low affinity immunoglobulin gamma Fc region receptor II isoform mIIB2 (mouse)

mFcgr2/iso:mIIB2


"A low affinity immunoglobulin gamma Fc region receptor II (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08101-2." [PRO:DNx, UniProtKB:P08101]


organism-sequence



PR:P08101-3

low affinity immunoglobulin gamma Fc region receptor II isoform mIIB1' (mouse)

mFcgr2/iso:mIIB1'


"A low affinity immunoglobulin gamma Fc region receptor II (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08101-3." [PRO:DNx, UniProtKB:P08101]


organism-sequence



PR:P08101-4

low affinity immunoglobulin gamma Fc region receptor II isoform mIIB3 (mouse)

mFcgr2/iso:mIIB3


"A low affinity immunoglobulin gamma Fc region receptor II (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08101-4." [PRO:DNx, UniProtKB:P08101]


organism-gene



PR:Q63203

low affinity immunoglobulin gamma Fc region receptor II (rat)

rFcgr2


"A low affinity immunoglobulin gamma Fc region receptor II that is encoded in the genome of rat." [OMA:Q63203, PRO:DNx]


modification



PR:000018508

low affinity immunoglobulin gamma Fc region receptor II, signal peptide removed form

Fcgr2/SigPep-


"A low affinity immunoglobulin gamma Fc region receptor II that has had the signal peptide removed." [PRO:DNx]


gene



PR:000001480

low affinity immunoglobulin gamma Fc region receptor II-a

FCGR2A


"An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the human FCGR2A gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P12318

low affinity immunoglobulin gamma Fc region receptor II-a (human)

hFCGR2A


"A low affinity immunoglobulin gamma Fc region receptor II-a that is encoded in the genome of human." [PRO:CNA, UniProtKB:P12318]


organism-sequence



PR:P12318-1

low affinity immunoglobulin gamma Fc region receptor II-a isoform h1 (human)

hFCGR2A/iso:h1


"A low affinity immunoglobulin gamma Fc region receptor II-a (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12318-1." [PRO:DNx, UniProtKB:P12318]


organism-sequence



PR:P12318-2

low affinity immunoglobulin gamma Fc region receptor II-a isoform h2 (human)

hFCGR2A/iso:h2


"A low affinity immunoglobulin gamma Fc region receptor II-a (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12318-2." [PRO:DNx, UniProtKB:P12318]


organism-modification



PR:000047386

low affinity immunoglobulin gamma Fc region receptor II-a, signal peptide removed form (human)

hFCGR2A/SigPep-


"A low affinity immunoglobulin gamma Fc region receptor II-a (human) that has had the signal peptide removed. UniProtKB:P12318, 34-317." [PRO:DNx, Reactome:R-HSA-197838]


organism-modification



PR:000047387

low affinity immunoglobulin gamma Fc region receptor II-a, signal peptide removed phosphorylated 1 (human)

hFCGR2A/SigPep-/Phos:1


"A low affinity immunoglobulin gamma Fc region receptor II-a (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at positions 288 and 304 of the amino acid sequence represented by UniProtKB:P12318. UniProtKB:P12318, 34-317, Tyr-288/Tyr-304, MOD:00048." [PRO:DNx, Reactome:R-HSA-2029069]


organism-gene



PR:P27645

low affinity immunoglobulin gamma Fc region receptor III (rat)

rFCGR2A


"A low affinity immunoglobulin gamma Fc region receptor II-a that is encoded in the genome of rat." [PRO:CNA]


organism-sequence



PR:P27645-1

low affinity immunoglobulin gamma Fc region receptor III isoform C (rat)

rFCGR2A/iso:C


"A low affinity immunoglobulin gamma Fc region receptor III (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27645-1." [PRO:DNx, UniProtKB:P27645]


organism-sequence



PR:P27645-2

low affinity immunoglobulin gamma Fc region receptor III isoform H (rat)

rFCGR2A/iso:H


"A low affinity immunoglobulin gamma Fc region receptor III (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27645-2." [PRO:DNx, UniProtKB:P27645]


organism-sequence



PR:P27645-3

low affinity immunoglobulin gamma Fc region receptor III isoform A (rat)

rFCGR2A/iso:A


"A low affinity immunoglobulin gamma Fc region receptor III (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27645-3." [PRO:DNx, UniProtKB:P27645]


organism-sequence



PR:P27645-4

low affinity immunoglobulin gamma Fc region receptor III isoform B (rat)

rFCGR2A/iso:B


"A low affinity immunoglobulin gamma Fc region receptor III (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27645-4." [PRO:DNx, UniProtKB:P27645]


organism-sequence



PR:P27645-5

low affinity immunoglobulin gamma Fc region receptor III isoform D (rat)

rFCGR2A/iso:D


"A low affinity immunoglobulin gamma Fc region receptor III (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27645-5." [PRO:DNx, UniProtKB:P27645]


organism-sequence



PR:P27645-6

low affinity immunoglobulin gamma Fc region receptor III isoform E (rat)

rFCGR2A/iso:E


"A low affinity immunoglobulin gamma Fc region receptor III (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27645-6." [PRO:DNx, UniProtKB:P27645]


organism-sequence



PR:P27645-7

low affinity immunoglobulin gamma Fc region receptor III isoform F (rat)

rFCGR2A/iso:F


"A low affinity immunoglobulin gamma Fc region receptor III (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27645-7." [PRO:DNx, UniProtKB:P27645]


organism-sequence



PR:P27645-8

low affinity immunoglobulin gamma Fc region receptor III isoform G (rat)

rFCGR2A/iso:G


"A low affinity immunoglobulin gamma Fc region receptor III (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27645-8." [PRO:DNx, UniProtKB:P27645]


modification



PR:000018510

low affinity immunoglobulin gamma Fc region receptor II-a, signal peptide removed form

FCGR2A/SigPep-


"A low affinity immunoglobulin gamma Fc region receptor II-a that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000047386

low affinity immunoglobulin gamma Fc region receptor II-a, signal peptide removed form (human)

hFCGR2A/SigPep-


"A low affinity immunoglobulin gamma Fc region receptor II-a (human) that has had the signal peptide removed. UniProtKB:P12318, 34-317." [PRO:DNx, Reactome:R-HSA-197838]


organism-modification



PR:000047387

low affinity immunoglobulin gamma Fc region receptor II-a, signal peptide removed phosphorylated 1 (human)

hFCGR2A/SigPep-/Phos:1


"A low affinity immunoglobulin gamma Fc region receptor II-a (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at positions 288 and 304 of the amino acid sequence represented by UniProtKB:P12318. UniProtKB:P12318, 34-317, Tyr-288/Tyr-304, MOD:00048." [PRO:DNx, Reactome:R-HSA-2029069]


gene



PR:000001481

low affinity immunoglobulin gamma Fc region receptor II-b

FCGR2B


"An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the human FCGR2B gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P31994

low affinity immunoglobulin gamma Fc region receptor II-b (human)

hFCGR2B


"A low affinity immunoglobulin gamma Fc region receptor II-b that is encoded in the genome of human." [PRO:CNA, UniProtKB:P31994]


organism-sequence



PR:P31994-1

low affinity immunoglobulin gamma Fc region receptor II-b isoform hIIB1 (human)

hFCGR2B/iso:hIIB1


"A low affinity immunoglobulin gamma Fc region receptor II-b (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31994-1." [PRO:DNx, UniProtKB:P31994]


organism-sequence



PR:P31994-2

low affinity immunoglobulin gamma Fc region receptor II-b isoform hIIB2 (human)

hFCGR2B/iso:hIIB2


"A low affinity immunoglobulin gamma Fc region receptor II-b (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31994-2." [PRO:DNx, UniProtKB:P31994]


organism-sequence



PR:P31994-3

low affinity immunoglobulin gamma Fc region receptor II-b isoform hIIB3 (human)

hFCGR2B/iso:hIIB3


"A low affinity immunoglobulin gamma Fc region receptor II-b (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31994-3." [PRO:DNx, UniProtKB:P31994]


organism-sequence



PR:P31994-4

low affinity immunoglobulin gamma Fc region receptor II-b isoform h4 (human)

hFCGR2B/iso:h4


"A low affinity immunoglobulin gamma Fc region receptor II-b (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31994-4." [PRO:DNx, UniProtKB:P31994]


organism-sequence



PR:P31994-5

low affinity immunoglobulin gamma Fc region receptor II-b isoform h5 (human)

hFCGR2B/iso:h5


"A low affinity immunoglobulin gamma Fc region receptor II-b (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31994-5." [PRO:DNx, UniProtKB:P31994]


organism-modification



PR:000047388

low affinity immunoglobulin gamma Fc region receptor II-b, signal peptide removed form (human)

hFCGR2B/SigPep-


"A low affinity immunoglobulin gamma Fc region receptor II-b (human) that has had the signal peptide removed. UniProtKB:P31994, 43-310." [PRO:DNx, Reactome:R-HSA-197854]


organism-modification



PR:000068403

low affinity immunoglobulin gamma Fc region receptor II-b deaminated 1 (human)

hFCGR2B/Deam:1


"A low affinity immunoglobulin gamma Fc region receptor II-b (human) that has been deaminated on the residue at the position equivalent to Gln-96 of the amino acid sequence represented by UniProtKB:P31994-1. Example: UniProtKB:P31994-1, Gln-96, MOD:00685." [IEDB_epitope:1385920, PRO:DNx]


gene



PR:000001482

low affinity immunoglobulin gamma Fc region receptor II-c

FCGR2C


"An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the human FCGR2C gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P31995

low affinity immunoglobulin gamma Fc region receptor II-c (human)

hFCGR2C


"A low affinity immunoglobulin gamma Fc region receptor II-c that is encoded in the genome of human." [PRO:CNA, UniProtKB:P31995]


organism-sequence



PR:P31995-1

low affinity immunoglobulin gamma Fc region receptor II-c isoform hIIC1 (human)

hFCGR2C/iso:hIIC1


"A low affinity immunoglobulin gamma Fc region receptor II-c (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31995-1." [PRO:DNx, UniProtKB:P31995]


organism-sequence



PR:P31995-2

low affinity immunoglobulin gamma Fc region receptor II-c isoform hIIC2 (human)

hFCGR2C/iso:hIIC2


"A low affinity immunoglobulin gamma Fc region receptor II-c (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31995-2." [PRO:DNx, UniProtKB:P31995]


organism-sequence



PR:P31995-3

low affinity immunoglobulin gamma Fc region receptor II-c isoform hIIC3 (human)

hFCGR2C/iso:hIIC3


"A low affinity immunoglobulin gamma Fc region receptor II-c (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31995-3." [PRO:DNx, UniProtKB:P31995]


organism-sequence



PR:P31995-4

low affinity immunoglobulin gamma Fc region receptor II-c isoform hIIC4 (human)

hFCGR2C/iso:hIIC4


"A low affinity immunoglobulin gamma Fc region receptor II-c (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31995-4." [PRO:DNx, UniProtKB:P31995]


gene



PR:000001483

low affinity immunoglobulin gamma Fc region receptor III

Fcgr3


"An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the mouse Fcgr3 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P08508

low affinity immunoglobulin gamma Fc region receptor III (mouse)

mFcgr3


"A low affinity immunoglobulin gamma Fc region receptor III that is encoded in the genome of mouse." [PRO:CNA, UniProtKB:P08508]


gene



PR:000001484

low affinity immunoglobulin gamma Fc region receptor III-A

FCGR3A


"An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the human FCGR3A gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P08637

low affinity immunoglobulin gamma Fc region receptor III-A (human)

hFCGR3A


"A low affinity immunoglobulin gamma Fc region receptor III-A that is encoded in the genome of human." [PRO:CNA, UniProtKB:P08637]


organism-modification



PR:000047389

low affinity immunoglobulin gamma Fc region receptor III-A, signal peptide removed form (human)

hFCGR3A/SigPep-


"A low affinity immunoglobulin gamma Fc region receptor III-A (human) that has had the signal peptide removed. UniProtKB:P08637, 17-254." [PRO:DNx, Reactome:R-HSA-197836]


gene



PR:000001485

low affinity immunoglobulin gamma Fc region receptor III-B

FCGR3B


"An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the human FCGR3B gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:A0A0B4J1G0

low affinity immunoglobulin gamma Fc region receptor III-A (mouse)

mFCGR3B


"A low affinity immunoglobulin gamma Fc region receptor III-B that is encoded in the genome of mouse." [PRO:CNA]


organism-gene



PR:O75015

low affinity immunoglobulin gamma Fc region receptor III-B (human)

hFCGR3B


"A low affinity immunoglobulin gamma Fc region receptor III-B that is encoded in the genome of human." [PRO:CNA, UniProtKB:O75015]


organism-modification



PR:000066544

low affinity immunoglobulin gamma Fc region receptor III-B, mature form (human)

hFCGR3B/mature


"A low affinity immunoglobulin gamma Fc region receptor III-B (human) that has had the signal peptide and propeptide removed. UniProtKB:O75015, 17-200." [PRO:DNx, Reactome:R-HSA-197857, Reactome:R-HSA-6803332]


organism-modification



PR:000066592

low affinity immunoglobulin gamma Fc region receptor III-B, mature GPI-anchored 1 (human)

hFCGR3B/mature/anchored:1


"A low affinity immunoglobulin gamma Fc region receptor III-B (human) that has had the signal peptide and propeptide removed, and that has been GPI-anchored on the residue at the position equivalent to Ser-200 of the amino acid sequence represented by UniProtKB:O75015. UniProtKB:O75015, 17-200, Ser-200, MOD:00171." [PRO:DNx, Reactome:R-HSA-8940738]


gene



PR:000007431

high affinity immunoglobulin epsilon receptor subunit alpha

FCER1A


"An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the human FCER1A gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P12319

high affinity immunoglobulin epsilon receptor subunit alpha (human)

hFCER1A


"A high affinity immunoglobulin epsilon receptor subunit alpha that is encoded in the genome of human." [PRO:DNx, UniProtKB:P12319]


organism-modification



PR:000047381

high affinity immunoglobulin epsilon receptor subunit alpha, signal peptide removed form (human)

hFCER1A/SigPep-


"A high affinity immunoglobulin epsilon receptor subunit alpha (human) that has had the signal peptide removed. UniProtKB:P12319, 26-257." [PRO:DNx, Reactome:R-HSA-197802]


organism-gene



PR:P12371

high affinity immunoglobulin epsilon receptor subunit alpha (rat)

rFCER1A


"A high affinity immunoglobulin epsilon receptor subunit alpha that is encoded in the genome of rat." [OMA:P12371, PRO:DNx]


organism-sequence



PR:P12371-1

high affinity immunoglobulin epsilon receptor subunit alpha isoform r1 (rat)

rFCER1A/iso:r1


"A high affinity immunoglobulin epsilon receptor subunit alpha (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12371-1." [PRO:DNx, UniProtKB:P12371]


organism-sequence



PR:P12371-2

high affinity immunoglobulin epsilon receptor subunit alpha isoform r2 (rat)

rFCER1A/iso:r2


"A high affinity immunoglobulin epsilon receptor subunit alpha (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12371-2." [PRO:DNx, UniProtKB:P12371]


organism-gene



PR:P20489

high affinity immunoglobulin epsilon receptor subunit alpha (mouse)

mFCER1A


"A high affinity immunoglobulin epsilon receptor subunit alpha that is encoded in the genome of mouse." [OMA:P20489, PRO:DNx]


modification



PR:000019856

high affinity immunoglobulin epsilon receptor subunit alpha, signal peptide removed form

FCER1A/SigPep-


"A high affinity immunoglobulin epsilon receptor subunit alpha that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000047381

high affinity immunoglobulin epsilon receptor subunit alpha, signal peptide removed form (human)

hFCER1A/SigPep-


"A high affinity immunoglobulin epsilon receptor subunit alpha (human) that has had the signal peptide removed. UniProtKB:P12319, 26-257." [PRO:DNx, Reactome:R-HSA-197802]