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Protein Ontology report - interleukin-6 receptor subunit alpha
PR:000001394 - http://purl.obolibrary.org/obo/PR_000001394
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001394   
  PRO nameinterleukin-6 receptor subunit alpha 
  Synonyms
PRO-Short-label: EXACT:IL6R
Gene-based: RELATED:Il6ra
Other: EXACT:CD126 | gp80 | IL-6 receptor subunit alpha | IL-6R 1 | IL-6R subunit alpha | IL-6R-alpha | IL-6RA | membrane glycoprotein 80
  Definition"A protein that is a translation product of the human IL6R gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence3                                                  Organism-Sequence 3                                        
         Modification5                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1708
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001394 interleukin-6 receptor subunit alpha
IL6R

organism-gene


PR:P08887 interleukin-6 receptor subunit alpha (human)
hIL6R

organism-sequence


PR:P08887-1 interleukin-6 receptor subunit alpha isoform 1 (human)
hIL6R/iso:1

organism-sequence


PR:P08887-2 interleukin-6 receptor subunit alpha isoform 2 (human)
hIL6R/iso:2

organism-modification


PR:000061562 interleukin-6 receptor subunit alpha isoform 2, signal peptide removed form (human)
hIL6R/iso:2/SigPep-

organism-modification


PR:000048029 interleukin-6 receptor subunit alpha, signal peptide removed form (human)
hIL6R/SigPep-

organism-modification


PR:000061562 interleukin-6 receptor subunit alpha isoform 2, signal peptide removed form (human)
hIL6R/iso:2/SigPep-

organism-modification


PR:000054602 interleukin-6 receptor subunit alpha O-glycosylated 1 (human)
hIL6R/OGlyco:1

organism-modification


PR:000054603 interleukin-6 receptor subunit alpha O-glycosylated 2 (human)
hIL6R/OGlyco:2

organism-gene


PR:P22272 interleukin-6 receptor subunit alpha (mouse)
mIL6R

organism-sequence


PR:P22272-1 interleukin-6 receptor subunit alpha isoform 1 (mouse)
mIL6R/iso:1
Yes
organism-modification


PR:000044514 interleukin-6 receptor subunit alpha isoform 1 soluble form (mouse)
mIL6R/iso:1/Clv:soluble
Yes
organism-gene


PR:P22273 interleukin-6 receptor subunit alpha (rat)
rIL6R

organism-gene


PR:Q5DWQ5 interleukin-6 receptor alpha chain (chicken)
chick-IL6R

sequence


PR:000001794 interleukin-6 receptor subunit alpha isoform 1
IL6R/iso:1

organism-sequence


PR:P22272-1 interleukin-6 receptor subunit alpha isoform 1 (mouse)
mIL6R/iso:1
Yes
organism-modification


PR:000044514 interleukin-6 receptor subunit alpha isoform 1 soluble form (mouse)
mIL6R/iso:1/Clv:soluble
Yes
modification


PR:000001798 interleukin-6 receptor subunit alpha isoform 1 soluble form
IL6R/iso:1/Clv:soluble

organism-modification


PR:000044514 interleukin-6 receptor subunit alpha isoform 1 soluble form (mouse)
mIL6R/iso:1/Clv:soluble
Yes
modification


PR:000026630 interleukin-6 receptor subunit alpha isoform 1, signal peptide removed form
IL6R/iso:1/SigPep-

sequence


PR:000001795 interleukin-6 receptor subunit alpha isoform 2
IL6R/iso:2

organism-sequence


PR:P08887-1 interleukin-6 receptor subunit alpha isoform 1 (human)
hIL6R/iso:1

modification


PR:000026634 interleukin-6 receptor subunit alpha isoform 2, signal peptide removed form
IL6R/iso:2/SigPep-

sequence


PR:000001796 interleukin-6 receptor subunit alpha isoform 3
IL6R/iso:3

organism-sequence


PR:P08887-2 interleukin-6 receptor subunit alpha isoform 2 (human)
hIL6R/iso:2

organism-modification


PR:000061562 interleukin-6 receptor subunit alpha isoform 2, signal peptide removed form (human)
hIL6R/iso:2/SigPep-

modification


PR:000018458 interleukin-6 receptor subunit alpha, signal peptide removed form
IL6R/SigPep-

modification


PR:000026630 interleukin-6 receptor subunit alpha isoform 1, signal peptide removed form
IL6R/iso:1/SigPep-

modification


PR:000026634 interleukin-6 receptor subunit alpha isoform 2, signal peptide removed form
IL6R/iso:2/SigPep-

organism-modification


PR:000048029 interleukin-6 receptor subunit alpha, signal peptide removed form (human)
hIL6R/SigPep-

organism-modification


PR:000061562 interleukin-6 receptor subunit alpha isoform 2, signal peptide removed form (human)
hIL6R/iso:2/SigPep-

modification


PR:000025429 interleukin-6 receptor subunit alpha proteolytic cleavage product
IL6R/ClvPrd

modification


PR:000001798 interleukin-6 receptor subunit alpha isoform 1 soluble form
IL6R/iso:1/Clv:soluble

organism-modification


PR:000044514 interleukin-6 receptor subunit alpha isoform 1 soluble form (mouse)
mIL6R/iso:1/Clv:soluble
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000044514 mIL6R/iso:1/Clv:soluble acts_upstream_of_or_withinGO:0070102 interleukin-6-mediated signaling pathway PMID:8477802
enablesGO:0004915 interleukin-6 receptor activity PMID:8477802
GO:0019981 interleukin-6 binding PMID:8477802
located_inGO:0005615 extracellular space PMID:8477802
PR:P22272-1 mIL6R/iso:1 acts_upstream_of_or_withinGO:0070102 interleukin-6-mediated signaling pathway MGI_ref:50330; PMID:1312474
enablesGO:0004915 interleukin-6 receptor activity MGI_ref:50330; PMID:1312474
GO:0019981 interleukin-6 binding MGI_ref:50330; PMID:1312474
located_inGO:0009986 cell surface MGI_ref:50330; PMID:1312474