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Protein Ontology report - tumor-associated calcium signal transducer
PR:000001407 - http://purl.obolibrary.org/obo/PR_000001407
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001407   
  PRO nametumor-associated calcium signal transducer 
  Synonyms
Other: RELATED:carcinoma antigen GA733 | GA733
  Definition"A protein with a core domain architecture consisting of a large N-terminal extracellular region, a single-pass transmembrane region and a very small cytoplasmic region. The extracellular region is composed of three distinct domains: a novel cysteine-rich N-terminal domain (GA733 type 1 motif), a cysteine-rich thyroglobulin type 1A domain (Thyroglobulin type-1 repeat (Pfam:PF00086)), and a unique nonglycosylated domain without cysteines (GA733 type 3 motif). It is an unusual cell-cell adhesion protein that does not exhibit any obvious relationship to the four known classes of adhesion molecules." [PMID:11080501
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene2                                                  Organism-Gene 7                                        
         Sequence2                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF002018
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000001407

tumor-associated calcium signal transducer

TNFRSF17


"A protein with a core domain architecture consisting of a large N-terminal extracellular region, a single-pass transmembrane region and a very small cytoplasmic region. The extracellular region is composed of three distinct domains: a novel cysteine-rich N-terminal domain (GA733 type 1 motif), a cysteine-rich thyroglobulin type 1A domain (Thyroglobulin type-1 repeat (Pfam:PF00086)), and a unique nonglycosylated domain without cysteines (GA733 type 3 motif). It is an unusual cell-cell adhesion protein that does not exhibit any obvious relationship to the four known classes of adhesion molecules." [PMID:11080501]


gene



PR:000001559

epithelial cell adhesion molecule

EPCAM


"A tumor-associated calcium signal transducer that is a translation product of the human EPCAM gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:O55159

epithelial cell adhesion molecule (rat)

rEPCAM


"An epithelial cell adhesion molecule that is encoded in the genome of rat." [OMA:O55159, PRO:DNx]


organism-sequence



PR:O55159-1

epithelial cell adhesion molecule isoform 1 (rat)

rEPCAM/iso:1


"An epithelial cell adhesion molecule isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:P16422

epithelial cell adhesion molecule (human)

hEPCAM


"An epithelial cell adhesion molecule that is encoded in the genome of human." [PRO:CNA, UniProtKB:P16422]


organism-modification



PR:000055818

epithelial cell adhesion molecule N-glycosylated 1 (human)

hEPCAM/NGlyco:1


"An epithelial cell adhesion molecule (human) that has been N-glycosylated at the residue equivalent to Asn-74 of the amino acid sequence represented by UniProtKB:P16422-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P16422-1, Asn-74, MOD:00160~GNO:G58001LT." [GlyGen:P16422-1, PMID:29741879, PRO:DNx]


organism-modification



PR:000061470

epithelial cell adhesion molecule, signal peptide removed form (human)

hEPCAM/SigPep-


"An epithelial cell adhesion molecule (human) that has had the signal peptide removed. UniProtKB:P16422, 24-314." [PRO:DNx, Reactome:R-HSA-375068]


organism-modification



PR:000068789

epithelial cell adhesion molecule methylated 1 (human)

hEPCAM/Me:1


"An epithelial cell adhesion molecule (human) that has been methylated on the residue at the position equivalent to Cys-38 of the amino acid sequence represented by UniProtKB:P16422. UniProtKB:P16422, Cys-38, MOD:00660." [IEDB_epitope:1058473, PRO:DNx]


organism-modification



PR:000081238

epithelial cell adhesion molecule cysteinylated 1 (human)

hEPCAM/Cyst:1


"An epithelial cell adhesion molecule (human) that has been cysteinylated on the residue at the position equivalent to Cys-135 of the amino acid sequence represented by UniProtKB:P16422. UniProtKB:P16422, Cys-135, MOD:00765." [IEDB_epitope:2127167, PRO:DNx]


organism-gene



PR:Q5F381

epithelial cell adhesion molecule (chicken)

chick-EPCAM


"An epithelial cell adhesion molecule that is encoded in the genome of chicken." [PRO:CNA]


organism-gene



PR:Q99JW5

epithelial cell adhesion molecule (mouse)

mEPCAM


"An epithelial cell adhesion molecule that is encoded in the genome of mouse." [OMA:Q99JW5, PRO:DNx]


organism-sequence



PR:Q99JW5-1

epithelial cell adhesion molecule isoform 1 (mouse)

mEPCAM/iso:1


"An epithelial cell adhesion molecule isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000042771

epithelial cell adhesion molecule isoform 1

EPCAM/iso:1


"An epithelial cell adhesion molecule that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99JW5-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:O55159-1

epithelial cell adhesion molecule isoform 1 (rat)

rEPCAM/iso:1


"An epithelial cell adhesion molecule isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:Q99JW5-1

epithelial cell adhesion molecule isoform 1 (mouse)

mEPCAM/iso:1


"An epithelial cell adhesion molecule isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


gene



PR:000016009

tumor-associated calcium signal transducer 2

TACSTD2


"A tumor-associated calcium signal transducer that is a translation product of the human TACSTD2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P09758

tumor-associated calcium signal transducer 2 (human)

hTACSTD2


"A tumor-associated calcium signal transducer 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P09758]


organism-modification



PR:000045661

tumor-associated calcium signal transducer 2 phosphorylated 1 (human)

hTACSTD2/Phos:1


"A tumor-associated calcium signal transducer 2 (human) that has been phosphorylated at Ser-303. UniProtKB:P09758, Ser-303, MOD:00046." [iPTMnet:P09758, PMID:7635574]


organism-modification



PR:000065752

tumor-associated calcium signal transducer 2 cysteinylated 1 (human)

hTACSTD2/Cyst:1


"A tumor-associated calcium signal transducer 2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-73 of the amino acid sequence represented by UniProtKB:P09758. UniProtKB:P09758, Cys-73, MOD:00765." [IEDB_epitope:1052181, PRO:DNx]


organism-gene



PR:Q6P9Z6

tumor-associated calcium signal transducer 2 (rat)

rTACSTD2


"A tumor-associated calcium signal transducer 2 that is encoded in the genome of rat." [OMA:Q6P9Z6, PRO:DNx]


organism-sequence



PR:Q6P9Z6-1

tumor-associated calcium signal transducer 2 isoform 1 (rat)

rTACSTD2/iso:1


"A tumor-associated calcium signal transducer 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:Q8BGV3

tumor-associated calcium signal transducer 2 (mouse)

mTACSTD2


"A tumor-associated calcium signal transducer 2 that is encoded in the genome of mouse." [OMA:Q8BGV3, PRO:DNx]


organism-sequence



PR:Q8BGV3-1

tumor-associated calcium signal transducer 2 isoform 1 (mouse)

mTACSTD2/iso:1


"A tumor-associated calcium signal transducer 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000041570

tumor-associated calcium signal transducer 2 isoform 1

TACSTD2/iso:1


"A tumor-associated calcium signal transducer 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BGV3-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:Q6P9Z6-1

tumor-associated calcium signal transducer 2 isoform 1 (rat)

rTACSTD2/iso:1


"A tumor-associated calcium signal transducer 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:Q8BGV3-1

tumor-associated calcium signal transducer 2 isoform 1 (mouse)

mTACSTD2/iso:1


"A tumor-associated calcium signal transducer 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]