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Protein Ontology report - interleukin-24
PR:000001474 - http://purl.obolibrary.org/obo/PR_000001474
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001474   
  PRO nameinterleukin-24 
  Synonyms
PRO-Short-label: EXACT:IL24
Gene-based: RELATED:MDA7 | ST16
Other: EXACT:IL-24 | IL-4-induced secreted protein | MDA-7 | melanoma differentiation-associated gene 7 protein | suppression of tumorigenicity 16 protein | Th2-specific cytokine FISP
  Definition"A class 2 cytokine, IL-10 type that is a translation product of the human IL24 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000001335 class 2 cytokine, IL-10 type
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 6                                        
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001474 interleukin-24
IL24

organism-gene


PR:Q13007 interleukin-24 (human)
hIL24

organism-sequence


PR:Q13007-1 interleukin-24 isoform h1 (human)
hIL24/iso:h1

organism-sequence


PR:Q13007-2 interleukin-24 isoform h2 (human)
hIL24/iso:h2

organism-sequence


PR:Q13007-3 interleukin-24 isoform h3 (human)
hIL24/iso:h3

organism-sequence


PR:Q13007-4 interleukin-24 isoform h4 (human)
hIL24/iso:h4

organism-modification


PR:000048011 interleukin-24, signal peptide removed form (human)
hIL24/SigPep-

organism-gene


PR:Q925S4 interleukin-24 (mouse)
mIL24

organism-sequence


PR:A3QQZ3 interleukin-24 isoform 2 (mouse)
mIL24/iso:2
Yes
organism-sequence


PR:Q925S4-1 interleukin-24 isoform 1 (mouse)
mIL24/iso:1
Yes
organism-gene


PR:Q9JI24 interleukin-24 (rat)
rIL24

sequence


PR:000035507 interleukin-24 isoform 1
IL24/iso:1

organism-sequence


PR:Q925S4-1 interleukin-24 isoform 1 (mouse)
mIL24/iso:1
Yes
sequence


PR:000035509 interleukin-24 isoform 2
IL24/iso:2
Yes
organism-sequence


PR:A3QQZ3 interleukin-24 isoform 2 (mouse)
mIL24/iso:2
Yes
modification


PR:000018506 interleukin-24, signal peptide removed form
IL24/SigPep-

organism-modification


PR:000048011 interleukin-24, signal peptide removed form (human)
hIL24/SigPep-

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035509 IL24/iso:2 acts_upstream_of_or_withinGO:0010951 negative regulation of endopeptidase activity MGI_ref:3821693; PMID:18708357
GO:0043066 negative regulation of apoptotic process MGI_ref:3821693; PMID:18708357
PR:A3QQZ3 mIL24/iso:2 acts_upstream_of_or_withinGO:0010951 negative regulation of endopeptidase activity MGI_ref:3821693; PMID:18708357
GO:0043066 negative regulation of apoptotic process MGI_ref:3821693; PMID:18708357
located_inGO:0005783 endoplasmic reticulum MGI_ref:3821693; PMID:18708357
PR:Q925S4-1 mIL24/iso:1 acts_upstream_of_or_withinGO:0008285 negative regulation of cell population proliferation MGI_ref:3821693; PMID:18708357
enablesGO:0005515 protein binding with PR:A3QQZ3 FISP cytokine variant FISP-sp (mouse) MGI_ref:3821693; PMID:18708357
located_inGO:0005576 extracellular region MGI_ref:3821693; PMID:18708357