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Protein Ontology report - muscarinic acetylcholine receptor
PR:000001488 - http://purl.obolibrary.org/obo/PR_000001488
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001488   
  PRO namemuscarinic acetylcholine receptor 
  Definition"A rhodopsin-like G-protein coupled receptor that is a translation product of the human CHRM1 to CHRM5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:WCB, PRO:XQ, Wikipedia:Muscarinic_acetylcholine_receptor
  CommentNote: The active form binds the neurotransmitter acetylcholine. They are more sensitive to muscarine than to nicotine. 
  PRO Categoryfamily 
  ParentPR:000001094 rhodopsin-like G-protein coupled receptor
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene5                                                  Organism-Gene 21                                        
         Sequence4                                                  Organism-Sequence 13                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF038548;IUPHARfam:2
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000001488

muscarinic acetylcholine receptor

LPAR5


"A rhodopsin-like G-protein coupled receptor that is a translation product of the human CHRM1 to CHRM5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:WCB, PRO:XQ, Wikipedia:Muscarinic_acetylcholine_receptor]


gene



PR:000001613

muscarinic acetylcholine receptor M1

CHRM1


"A muscarinic acetylcholine receptor that is a translation product of the human CHRM1 gene or a 1:1 ortholog thereof. This receptor mediates slow excitatory postsynaptic potential in the postganglionic nerve and is also expressed in exocrine glands and in the central nervous system." [PRO:WCB, Wikipedia:Muscarinic_acetylcholine_receptor]


organism-gene



PR:P08482

muscarinic acetylcholine receptor M1 (rat)

rCHRM1


"A muscarinic acetylcholine receptor M1 that is encoded in the genome of rat." [OMA:P08482, PRO:DNx]


organism-sequence



PR:P08482-1

muscarinic acetylcholine receptor M1 isoform 1 (rat)

rCHRM1/iso:1


"A muscarinic acetylcholine receptor M1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:P11229

muscarinic acetylcholine receptor M1 (human)

hCHRM1


"A muscarinic acetylcholine receptor M1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P11229]


organism-sequence



PR:P11229-1

muscarinic acetylcholine receptor M1 isoform 1 (human)

hCHRM1/iso:1


"A muscarinic acetylcholine receptor M1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P11229-2

muscarinic acetylcholine receptor M1 isoform h2 (human)

hCHRM1/iso:h2


"A muscarinic acetylcholine receptor M1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P11229-2." [PRO:DNx, UniProtKB:P11229]


organism-gene



PR:P12657

muscarinic acetylcholine receptor M1 (mouse)

mCHRM1


"A muscarinic acetylcholine receptor M1 that is encoded in the genome of mouse." [OMA:P12657, PRO:DNx]


organism-sequence



PR:P12657-1

muscarinic acetylcholine receptor M1 isoform 1 (mouse)

mCHRM1/iso:1


"A muscarinic acetylcholine receptor M1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:P56489

muscarinic acetylcholine receptor M1 (Macaca mulatta)

RhMonkey-CHRM1


"A muscarinic acetylcholine receptor M1 that is encoded in the genome of Macaca mulatta." [OMA:P56489, PRO:DNx]


sequence



PR:000038834

muscarinic acetylcholine receptor M1 isoform 1

CHRM1/iso:1


"A muscarinic acetylcholine receptor M1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P11229-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P08482-1

muscarinic acetylcholine receptor M1 isoform 1 (rat)

rCHRM1/iso:1


"A muscarinic acetylcholine receptor M1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P11229-1

muscarinic acetylcholine receptor M1 isoform 1 (human)

hCHRM1/iso:1


"A muscarinic acetylcholine receptor M1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P12657-1

muscarinic acetylcholine receptor M1 isoform 1 (mouse)

mCHRM1/iso:1


"A muscarinic acetylcholine receptor M1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


gene



PR:000001614

muscarinic acetylcholine receptor M2

CHRM2


"A muscarinic acetylcholine receptor that is a translation product of the human CHRM2 gene or a 1:1 ortholog thereof. This receptor is expressed in cardiac tissues and acts to slow the heart rate to normal after sympathetic nervous system stimulation." [PRO:WCB, Wikipedia:Muscarinic_acetylcholine_receptor]


organism-gene



PR:P06199

muscarinic acetylcholine receptor M2 (pig)

pig-CHRM2


"A muscarinic acetylcholine receptor M2 that is encoded in the genome of pig." [OMA:P06199, PRO:DNx]


organism-gene



PR:P08172

muscarinic acetylcholine receptor M2 (human)

hCHRM2


"A muscarinic acetylcholine receptor M2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P08172]


organism-sequence



PR:P08172-1

muscarinic acetylcholine receptor M2 isoform 1 (human)

hCHRM2/iso:1


"A muscarinic acetylcholine receptor M2 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-gene



PR:P10980

muscarinic acetylcholine receptor M2 (rat)

rCHRM2


"A muscarinic acetylcholine receptor M2 that is encoded in the genome of rat." [OMA:P10980, PRO:DNx]


organism-sequence



PR:P10980-1

muscarinic acetylcholine receptor M2 isoform 1 (rat)

rCHRM2/iso:1


"A muscarinic acetylcholine receptor M2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:P30372

muscarinic acetylcholine receptor M2 (chicken)

chick-CHRM2


"A muscarinic acetylcholine receptor M2 that is encoded in the genome of chicken." [OMA:P30372, PRO:DNx]


organism-gene



PR:Q9ERZ4

muscarinic acetylcholine receptor M2 (mouse)

mCHRM2


"A muscarinic acetylcholine receptor M2 that is encoded in the genome of mouse." [OMA:Q9ERZ4, PRO:DNx]


organism-sequence



PR:Q9ERZ4-1

muscarinic acetylcholine receptor M2 isoform 1 (mouse)

mCHRM2/iso:1


"A muscarinic acetylcholine receptor M2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000038734

muscarinic acetylcholine receptor M2 isoform 1

CHRM2/iso:1


"A muscarinic acetylcholine receptor M2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08172-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P08172-1

muscarinic acetylcholine receptor M2 isoform 1 (human)

hCHRM2/iso:1


"A muscarinic acetylcholine receptor M2 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P10980-1

muscarinic acetylcholine receptor M2 isoform 1 (rat)

rCHRM2/iso:1


"A muscarinic acetylcholine receptor M2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:Q9ERZ4-1

muscarinic acetylcholine receptor M2 isoform 1 (mouse)

mCHRM2/iso:1


"A muscarinic acetylcholine receptor M2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


gene



PR:000001615

muscarinic acetylcholine receptor M3

CHRM3


"A muscarinic acetylcholine receptor that is a translation product of the human CHRM3 gene or a 1:1 ortholog thereof. This receptor is expressed in many glands, in lungs, and in the smooth muscles of blood vessels." [PRO:WCB, Wikipedia:Muscarinic_acetylcholine_receptor]


organism-gene



PR:P08483

muscarinic acetylcholine receptor M3 (rat)

rCHRM3


"A muscarinic acetylcholine receptor M3 that is encoded in the genome of rat." [OMA:P08483, PRO:DNx]


organism-sequence



PR:P08483-1

muscarinic acetylcholine receptor M3 isoform 1 (rat)

rCHRM3/iso:1


"A muscarinic acetylcholine receptor M3 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:P16395

muscarinic acetylcholine receptor DM1 (fruit fly)

fly-CHRM3


"A muscarinic acetylcholine receptor M3 that is encoded in the genome of fruit fly." [OMA:P16395, PRO:DNx]


organism-sequence



PR:P16395-1

muscarinic acetylcholine receptor DM1 isoform B (fruit fly)

fly-CHRM3/iso:B


"A muscarinic acetylcholine receptor DM1 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16395-1." [PRO:DNx, UniProtKB:P16395]


organism-sequence



PR:P16395-2

muscarinic acetylcholine receptor DM1 isoform A (fruit fly)

fly-CHRM3/iso:A


"A muscarinic acetylcholine receptor DM1 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16395-2." [PRO:DNx, UniProtKB:P16395]


organism-gene



PR:P20309

muscarinic acetylcholine receptor M3 (human)

hCHRM3


"A muscarinic acetylcholine receptor M3 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P20309]


organism-gene



PR:P49578

muscarinic acetylcholine receptor M3 (chicken)

chick-CHRM3


"A muscarinic acetylcholine receptor M3 that is encoded in the genome of chicken." [PRO:WCB]


organism-gene



PR:Q9ERZ3

muscarinic acetylcholine receptor M3 (mouse)

mCHRM3


"A muscarinic acetylcholine receptor M3 that is encoded in the genome of mouse." [OMA:Q9ERZ3, PRO:DNx]


organism-sequence



PR:Q9ERZ3-1

muscarinic acetylcholine receptor M3 isoform 1 (mouse)

mCHRM3/iso:1


"A muscarinic acetylcholine receptor M3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000043162

muscarinic acetylcholine receptor M3 isoform 1

CHRM3/iso:1


"A muscarinic acetylcholine receptor M3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9ERZ3-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P08483-1

muscarinic acetylcholine receptor M3 isoform 1 (rat)

rCHRM3/iso:1


"A muscarinic acetylcholine receptor M3 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:Q9ERZ3-1

muscarinic acetylcholine receptor M3 isoform 1 (mouse)

mCHRM3/iso:1


"A muscarinic acetylcholine receptor M3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


gene



PR:000001616

muscarinic acetylcholine receptor M4

CHRM4


"A muscarinic acetylcholine receptor that is a translation product of the human CHRM4 gene or a 1:1 ortholog thereof. This receptor is expressed in the central nervous system." [PRO:WCB, Wikipedia:Muscarinic_acetylcholine_receptor]


organism-gene



PR:P08173

muscarinic acetylcholine receptor M4 (human)

hCHRM4


"A muscarinic acetylcholine receptor M4 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P08173]


organism-gene



PR:P08485

muscarinic acetylcholine receptor M4 (rat)

rCHRM4


"A muscarinic acetylcholine receptor M4 that is encoded in the genome of rat." [OMA:P08485, PRO:DNx]


organism-gene



PR:P17200

muscarinic acetylcholine receptor M4 (chicken)

chick-CHRM4


"A muscarinic acetylcholine receptor M4 that is encoded in the genome of chicken." [OMA:P17200, PRO:DNx]


organism-gene



PR:P32211

muscarinic acetylcholine receptor M4 (mouse)

mCHRM4


"A muscarinic acetylcholine receptor M4 that is encoded in the genome of mouse." [OMA:P32211, PRO:DNx]


gene



PR:000001617

muscarinic acetylcholine receptor M5

CHRM5


"A muscarinic acetylcholine receptor that is a translation product of the human CHRM5 gene or a 1:1 ortholog thereof. Its expression pattern is yet to be elucidated." [PRO:WCB, Wikipedia:Muscarinic_acetylcholine_receptor]


organism-gene



PR:P08911

muscarinic acetylcholine receptor M5 (rat)

rCHRM5


"A muscarinic acetylcholine receptor M5 that is encoded in the genome of rat." [OMA:P08911, PRO:DNx]


organism-gene



PR:P08912

muscarinic acetylcholine receptor M5 (human)

hCHRM5


"A muscarinic acetylcholine receptor M5 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P08912]


organism-sequence



PR:P08912-1

muscarinic acetylcholine receptor M5 isoform 1 (human)

hCHRM5/iso:1


"A muscarinic acetylcholine receptor M5 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-gene



PR:Q920H4

muscarinic acetylcholine receptor M5 (mouse)

mCHRM5


"A muscarinic acetylcholine receptor M5 that is encoded in the genome of mouse." [OMA:Q920H4, PRO:DNx]


organism-sequence



PR:Q920H4-1

muscarinic acetylcholine receptor M5 isoform 1 (mouse)

mCHRM5/iso:1


"A muscarinic acetylcholine receptor M5 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000038754

muscarinic acetylcholine receptor M5 isoform 1

CHRM5/iso:1


"A muscarinic acetylcholine receptor M5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08912-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P08912-1

muscarinic acetylcholine receptor M5 isoform 1 (human)

hCHRM5/iso:1


"A muscarinic acetylcholine receptor M5 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q920H4-1

muscarinic acetylcholine receptor M5 isoform 1 (mouse)

mCHRM5/iso:1


"A muscarinic acetylcholine receptor M5 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]