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family
 |


|
 PR:000001673 |
   lysophospholipid (S1P) receptor
 |
   SSTR5
 |
  "An LPAR1/S1PR1-like lysophospholipid receptor that is a translation product of the human S1PR1, S1PR2, S1PR3, S1PR4, or S1PR5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues." [PRO:DAN, PRO:WCB]
 |

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gene
 |


|
 PR:000001706 |
   sphingosine 1-phosphate receptor 1
 |
   S1PR1
 |
  "A lysophospholipid (S1P) receptor that is a translation product of the human S1PR1 gene or a 1:1 ortholog thereof. The receptor is specifically expressed in endothelial cells, and to a lesser extent, in vascular smooth muscle cells, fibroblasts, melanocytes, and cells of epithelioid origin." [PRO:WCB, UniProtKB:P21453]
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organism-gene
 |


|
 PR:O08530 |
   sphingosine 1-phosphate receptor 1 (mouse)
 |
   mS1PR1
 |
  "A sphingosine 1-phosphate receptor 1 that is encoded in the genome of mouse." [OMA:O08530, PRO:DNx]
 |

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organism-sequence
 |


|
 PR:O08530-1 |
   sphingosine 1-phosphate receptor 1 isoform 1 (mouse)
 |
   mS1PR1/iso:1
 |
  "A sphingosine 1-phosphate receptor 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
 |

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|  |  |  |  |  |  |
 |  |  |
organism-gene
 |


|
 PR:P21453 |
   sphingosine 1-phosphate receptor 1 (human)
 |
   hS1PR1
 |
  "A sphingosine 1-phosphate receptor 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P21453]
 |

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organism-sequence
 |


|
 PR:P21453-1 |
   sphingosine 1-phosphate receptor 1 isoform 1 (human)
 |
   hS1PR1/iso:1
 |
  "A sphingosine 1-phosphate receptor 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
 |

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organism-modification
 |


|
 PR:000045710 |
   sphingosine 1-phosphate receptor 1 phosphorylated 1 (human)
 |
   hS1PR1/Phos:1
 |
  "A sphingosine 1-phosphate receptor 1 (human) that has been phosphorylated at Thr-236. UniProtKB:P21453, Thr-236, MOD:00047." [iPTMnet:P21453, PMID:11583630]
 |

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organism-gene
 |


|
 PR:P48303 |
   sphingosine 1-phosphate receptor 1 (rat)
 |
   rS1PR1
 |
  "A sphingosine 1-phosphate receptor 1 that is encoded in the genome of rat." [OMA:P48303, PRO:DNx]
 |

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organism-modification
 |


|
 PR:000058963 |
   sphingosine 1-phosphate receptor 1 N-glycosylated 1 (rat)
 |
   rS1PR1/NGlyco:1
 |
  "A sphingosine 1-phosphate receptor 1 (rat) that has been N-glycosylated at the residue equivalent to Asn-31 of the amino acid sequence represented by UniProtKB:P48303-1, in which the glycan structure is represented by GlyTouCan:G30159WR. Example: UniProtKB:P48303-1, Asn-31, MOD:00160~GNO:G30159WR." [GlyGen:P48303-1, PMID:24090084, PRO:DNx]
 |

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organism-modification
 |


|
 PR:000058964 |
   sphingosine 1-phosphate receptor 1 N-glycosylated 2 (rat)
 |
   rS1PR1/NGlyco:2
 |
  "A sphingosine 1-phosphate receptor 1 (rat) that has been N-glycosylated at the residue equivalent to Asn-31 of the amino acid sequence represented by UniProtKB:P48303-1, in which the glycan composition is represented by GlyTouCan:G88725PI. Example: UniProtKB:P48303-1, Asn-31, MOD:00160~GNO:G88725PI." [GlyGen:P48303-1, PMID:24090084, PRO:DNx]
 |

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organism-gene
 |


|
 PR:Q9DDK4 |
   sphingosine 1-phosphate receptor 1 (zebrafish)
 |
   z-S1PR1
 |
  "A sphingosine 1-phosphate receptor 1 that is encoded in the genome of zebrafish." [PRO:WCB]
 |

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 |  |  |
sequence
 |


|
 PR:000039053 |
   sphingosine 1-phosphate receptor 1 isoform 1
 |
   S1PR1/iso:1
 |
  "A sphingosine 1-phosphate receptor 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P21453-1 or a 1:1 ortholog thereof." [PRO:DNx]
 |

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|  |  |  |  |  |  |  |  |
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organism-sequence
 |


|
 PR:O08530-1 |
   sphingosine 1-phosphate receptor 1 isoform 1 (mouse)
 |
   mS1PR1/iso:1
 |
  "A sphingosine 1-phosphate receptor 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
 |

| 
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|  |  |  |  |  |  |  |  |
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organism-sequence
 |


|
 PR:P21453-1 |
   sphingosine 1-phosphate receptor 1 isoform 1 (human)
 |
   hS1PR1/iso:1
 |
  "A sphingosine 1-phosphate receptor 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
 |

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|  |  |  |  |
 |  |  |  |  |
gene
 |


|
 PR:000001707 |
   sphingosine 1-phosphate receptor 2
 |
   S1PR2
 |
  "A lysophospholipid (S1P) receptor that is a translation product of the human S1PR2 gene or a 1:1 ortholog thereof." [PRO:WCB]
 |

| 
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|  |  |  |  |  |  |
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organism-gene
 |


|
 PR:O95136 |
   sphingosine 1-phosphate receptor 2 (human)
 |
   hS1PR2
 |
  "A sphingosine 1-phosphate receptor 2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:O95136]
 |

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|  |  |  |  |  |  |
 |  |  |
organism-gene
 |


|
 PR:P47752 |
   sphingosine 1-phosphate receptor 2 (rat)
 |
   rS1PR2
 |
  "A sphingosine 1-phosphate receptor 2 that is encoded in the genome of rat." [OMA:P47752, PRO:DNx]
 |

| 
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|  |  |  |  |  |  |  |  |
 |
organism-sequence
 |


|
 PR:P47752-1 |
   sphingosine 1-phosphate receptor 2 isoform 1 (rat)
 |
   rS1PR2/iso:1
 |
  "A sphingosine 1-phosphate receptor 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
 |

| 
|
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|  |  |  |  |  |  |
 |  |  |
organism-gene
 |


|
 PR:P52592 |
   sphingosine 1-phosphate receptor 2 (mouse)
 |
   mS1PR2
 |
  "A sphingosine 1-phosphate receptor 2 that is encoded in the genome of mouse." [OMA:P52592, PRO:DNx]
 |

| 
|
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|  |  |  |  |  |  |  |  |
 |
organism-sequence
 |


|
 PR:P52592-1 |
   sphingosine 1-phosphate receptor 2 isoform 1 (mouse)
 |
   mS1PR2/iso:1
 |
  "A sphingosine 1-phosphate receptor 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
 |

| 
|
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|  |  |  |  |  |  |
 |  |  |
organism-gene
 |


|
 PR:Q9I8K8 |
   sphingosine 1-phosphate receptor 2 (zebrafish)
 |
   z-S1PR2
 |
  "A sphingosine 1-phosphate receptor 2 that is encoded in the genome of zebrafish." [OMA:Q9I8K8, PRO:DNx]
 |

| 
|
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 |
|  |  |  |  |  |  |
 |  |  |
sequence
 |


|
 PR:000039703 |
   sphingosine 1-phosphate receptor 2 isoform 1
 |
   S1PR2/iso:1
 |
  "A sphingosine 1-phosphate receptor 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P52592-1 or a 1:1 ortholog thereof." [PRO:DNx]
 |

| 
|
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|  |  |  |  |  |  |  |  |
 |
organism-sequence
 |


|
 PR:P47752-1 |
   sphingosine 1-phosphate receptor 2 isoform 1 (rat)
 |
   rS1PR2/iso:1
 |
  "A sphingosine 1-phosphate receptor 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
 |

| 
|
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|  |  |  |  |  |  |  |  |
 |
organism-sequence
 |


|
 PR:P52592-1 |
   sphingosine 1-phosphate receptor 2 isoform 1 (mouse)
 |
   mS1PR2/iso:1
 |
  "A sphingosine 1-phosphate receptor 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
 |

| 
|
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|  |  |  |  |
 |  |  |  |  |
gene
 |


|
 PR:000001708 |
   sphingosine 1-phosphate receptor 3
 |
   S1PR3
 |
  "A lysophospholipid (S1P) receptor that is a translation product of the human S1PR3 gene or a 1:1 ortholog thereof. It is expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver." [PRO:WCB, UniProtKB:Q99500]
 |

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|  |  |  |  |  |  |
 |  |  |
organism-gene
 |


|
 PR:Q99500 |
   sphingosine 1-phosphate receptor 3 (human)
 |
   hS1PR3
 |
  "A sphingosine 1-phosphate receptor 3 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q99500]
 |

| 
|
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|  |  |  |  |  |  |
 |  |  |
organism-gene
 |


|
 PR:Q9Z0U9 |
   sphingosine 1-phosphate receptor 3 (mouse)
 |
   mS1PR3
 |
  "A sphingosine 1-phosphate receptor 3 that is encoded in the genome of mouse." [OMA:Q9Z0U9, PRO:DNx]
 |

| 
|
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 |
|  |  |  |  |
 |  |  |  |  |
gene
 |


|
 PR:000001709 |
   sphingosine 1-phosphate receptor 4
 |
   S1PR4
 |
  "A lysophospholipid (S1P) receptor that is a translation product of the human S1PR4 gene or a 1:1 ortholog thereof. This receptor is specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung." [PRO:WCB, UniProtKB:O95977]
 |

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|  |  |  |  |  |  |
 |  |  |
organism-gene
 |


|
 PR:O95977 |
   sphingosine 1-phosphate receptor 4 (human)
 |
   hS1PR4
 |
  "A sphingosine 1-phosphate receptor 4 that is encoded in the genome of human." [PRO:WCB, UniProtKB:O95977]
 |

| 
|
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|  |  |  |  |  |  |  |  |
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organism-modification
 |


|
 PR:000067409 |
   sphingosine 1-phosphate receptor 4 methylated 1 (human)
 |
   hS1PR4/Me:1
 |
  "A sphingosine 1-phosphate receptor 4 (human) that has been methylated on the residue at the position equivalent to Cys-315 of the amino acid sequence represented by UniProtKB:O95977. UniProtKB:O95977, Cys-315, MOD:00660." [IEDB_epitope:1009903, PRO:DNx]
 |

| 
|
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 |
|  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000070735 |
   sphingosine 1-phosphate receptor 4 deaminated 1 (human)
 |
   hS1PR4/Deam:1
 |
  "A sphingosine 1-phosphate receptor 4 (human) that has been deaminated on the residue at the position equivalent to Asn-64 of the amino acid sequence represented by UniProtKB:O95977. UniProtKB:O95977, Asn-64, MOD:00684." [IEDB_epitope:2141148, PRO:DNx]
 |

| 
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|  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000084347 |
   sphingosine 1-phosphate receptor 4 cysteinylated 1 (human)
 |
   hS1PR4/Cyst:1
 |
  "A sphingosine 1-phosphate receptor 4 (human) that has been cysteinylated on the residue at the position equivalent to Cys-315 of the amino acid sequence represented by UniProtKB:O95977. UniProtKB:O95977, Cys-315, MOD:00765." [IEDB_epitope:1582571, PRO:DNx]
 |

| 
|
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|  |  |  |  |  |  |
 |  |  |
organism-gene
 |


|
 PR:Q9Z0L1 |
   sphingosine 1-phosphate receptor 4 (mouse)
 |
   mS1PR4
 |
  "A sphingosine 1-phosphate receptor 4 that is encoded in the genome of mouse." [OMA:Q9Z0L1, PRO:DNx]
 |

| 
|
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 |
 |
|  |  |  |  |
 |  |  |  |  |
gene
 |


|
 PR:000001710 |
   sphingosine 1-phosphate receptor 5
 |
   S1PR5
 |
  "A lysophospholipid (S1P) receptor that is a translation product of the human S1PR5 gene or a 1:1 ortholog thereof. Although widely expressed in the brain, most prominently in the corpus callosum, it is detected at a low level in most tissues." [PRO:WCB, UniProtKB:Q9H228]
 |

| 
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|  |  |  |  |  |  |
 |  |  |
organism-gene
 |


|
 PR:Q91X56 |
   sphingosine 1-phosphate receptor 5 (mouse)
 |
   mS1PR5
 |
  "A sphingosine 1-phosphate receptor 5 that is encoded in the genome of mouse." [OMA:Q91X56, PRO:DNx]
 |

| 
|
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|  |  |  |  |  |  |  |  |
 |
organism-sequence
 |


|
 PR:Q91X56-1 |
   sphingosine 1-phosphate receptor 5 isoform 1 (mouse)
 |
   mS1PR5/iso:1
 |
  "A sphingosine 1-phosphate receptor 5 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
 |

| 
|
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|
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 |
|  |  |  |  |  |  |
 |  |  |
organism-gene
 |


|
 PR:Q9H228 |
   sphingosine 1-phosphate receptor 5 (human)
 |
   hS1PR5
 |
  "A sphingosine 1-phosphate receptor 5 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q9H228]
 |

| 
|
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 |
|  |  |  |  |  |  |  |  |
 |
organism-sequence
 |


|
 PR:Q9H228-1 |
   sphingosine 1-phosphate receptor 5 isoform h1 (human)
 |
   hS1PR5/iso:h1
 |
  "A sphingosine 1-phosphate receptor 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H228-1." [PRO:DNx, UniProtKB:Q9H228]
 |

| 
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|  |  |  |  |  |  |  |  |
 |
organism-sequence
 |


|
 PR:Q9H228-2 |
   sphingosine 1-phosphate receptor 5 isoform h2 (human)
 |
   hS1PR5/iso:h2
 |
  "A sphingosine 1-phosphate receptor 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H228-2." [PRO:DNx, UniProtKB:Q9H228]
 |

| 
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|  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000066925 |
   sphingosine 1-phosphate receptor 5 phosphorylated 1 (human)
 |
   hS1PR5/Phos:1
 |
  "A sphingosine 1-phosphate receptor 5 (human) that has been phosphorylated on the residue at the position equivalent to Ser-246 of the amino acid sequence represented by UniProtKB:Q9H228-1. Example: UniProtKB:Q9H228-1, Ser-246, MOD:00046." [IEDB_epitope:912348, PRO:DNx]
 |

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|  |  |  |  |  |  |
 |  |  |
organism-gene
 |


|
 PR:Q9JKM5 |
   sphingosine 1-phosphate receptor 5 (rat)
 |
   rS1PR5
 |
  "A sphingosine 1-phosphate receptor 5 that is encoded in the genome of rat." [OMA:Q9JKM5, PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
organism-sequence
 |


|
 PR:Q9JKM5-1 |
   sphingosine 1-phosphate receptor 5 isoform 1 (rat)
 |
   rS1PR5/iso:1
 |
  "A sphingosine 1-phosphate receptor 5 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
sequence
 |


|
 PR:000042251 |
   sphingosine 1-phosphate receptor 5 isoform 1
 |
   S1PR5/iso:1
 |
  "A sphingosine 1-phosphate receptor 5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q91X56-1 or a 1:1 ortholog thereof." [PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
organism-sequence
 |


|
 PR:Q91X56-1 |
   sphingosine 1-phosphate receptor 5 isoform 1 (mouse)
 |
   mS1PR5/iso:1
 |
  "A sphingosine 1-phosphate receptor 5 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
organism-sequence
 |


|
 PR:Q9JKM5-1 |
   sphingosine 1-phosphate receptor 5 isoform 1 (rat)
 |
   rS1PR5/iso:1
 |
  "A sphingosine 1-phosphate receptor 5 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
 |

| 
|
|
|