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gene
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PR:000001719 |
transient receptor potential cation channel TRPM8
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TRPM8
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"A transient receptor potential channel protein that is a translation product of the human TRPM8 gene or a 1:1 ortholog thereof. TRPM8 is a member of the subfamily M of the transient receptor potential cation channels (TRPs). In common with other TRPs, these proteins have amino- and carboxyl-terminal intracellular domains separated by a domain containing six transmembrane helices (S1-S6) in which the last two helices (S5 and S6) flank a loop, called the pore loop, which determines ion selectivity.TRPM8 forms a nonselective cation channel that is activated by cold and by menthol and other substances that produce the sensation of coolness. These channels exhibit voltage-dependance and regulation by phosphatidylinositol-4,5-bisphosphate (PIP2)." [PMID:15852009, PRO:CNA]
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organism-gene
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PR:Q7Z2W7 |
transient receptor potential cation channel subfamily M member 8 (human)
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hTRPM8
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"A transient receptor potential cation channel TRPM8 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q7Z2W7]
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organism-sequence
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PR:Q7Z2W7-1 |
transient receptor potential cation channel subfamily M member 8 isoform 1 (human)
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hTRPM8/iso:1
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"A transient receptor potential cation channel TRPM8 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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organism-sequence
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PR:Q7Z2W7-2 |
transient receptor potential cation channel subfamily M member 8 isoform 2 (human)
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hTRPM8/iso:2
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"A transient receptor potential cation channel TRPM8 isoform 2 that is encoded in the genome of human." [PRO:CNA]
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organism-sequence
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PR:Q7Z2W7-3 |
transient receptor potential cation channel subfamily M member 8 isoform 3 (human)
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hTRPM8/iso:3
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"A transient receptor potential cation channel TRPM8 isoform 3 that is encoded in the genome of human." [PRO:CNA]
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organism-sequence
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PR:Q7Z2W7-4 |
transient receptor potential cation channel subfamily M member 8 isoform h4 (human)
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hTRPM8/iso:h4
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"A transient receptor potential cation channel subfamily M member 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z2W7-4." [PRO:DNx, UniProtKB:Q7Z2W7]
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organism-modification
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PR:000071823 |
transient receptor potential cation channel subfamily M member 8 phosphorylated 1 (human)
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hTRPM8/Phos:1
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"A transient receptor potential cation channel subfamily M member 8 (human) that has been phosphorylated on the residue at the position equivalent to Ser-341 of the amino acid sequence represented by UniProtKB:Q7Z2W7-1. Example: UniProtKB:Q7Z2W7-1, Ser-341, MOD:00046." [IEDB_epitope:2145690, PRO:DNx]
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organism-modification
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PR:000081248 |
transient receptor potential cation channel subfamily M member 8 phosphorylated 2 (human)
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hTRPM8/Phos:2
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"A transient receptor potential cation channel subfamily M member 8 (human) that has been phosphorylated on the residue at the position equivalent to Thr-448 of the amino acid sequence represented by UniProtKB:Q7Z2W7-1. Example: UniProtKB:Q7Z2W7-1, Thr-448, MOD:00047." [IEDB_epitope:2148122, PRO:DNx]
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organism-gene
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PR:Q8R455 |
transient receptor potential cation channel subfamily M member 8 (rat)
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rTRPM8
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"A transient receptor potential cation channel TRPM8 that is encoded in the genome of rat." [OMA:Q8R455, PRO:DNx]
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organism-gene
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PR:Q8R4D5 |
transient receptor potential cation channel subfamily M member 8 (mouse)
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mTRPM8
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"A transient receptor potential cation channel TRPM8 that is encoded in the genome of mouse." [OMA:Q8R4D5, PRO:DNx]
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organism-sequence
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PR:Q8R4D5-1 |
transient receptor potential cation channel subfamily M member 8 isoform 1 (mouse)
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mTRPM8/iso:1
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"A transient receptor potential cation channel TRPM8 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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organism-modification
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PR:000036607 |
transient receptor potential cation channel TRPM8 isoform 1 N-glycosylated 1 (mouse)
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mTRPM8/iso:1/NGlyco:1
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"A transient receptor potential cation channel TRPM8 isoform 1 N-glycosylated 1 in mouse. UniProtKB:Q8R4D5-1, Asn-934, MOD:00160." [PMID:17015441, PRO:HJD]
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sequence
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PR:000001720 |
transient receptor potential cation channel TRPM8 isoform 1
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TRPM8/iso:1
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"A transient receptor potential cation channel TRPM8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z2W7-1 or a 1:1 ortholog thereof." [PRO:CNA]
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organism-sequence
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PR:Q7Z2W7-1 |
transient receptor potential cation channel subfamily M member 8 isoform 1 (human)
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hTRPM8/iso:1
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"A transient receptor potential cation channel TRPM8 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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organism-sequence
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PR:Q8R4D5-1 |
transient receptor potential cation channel subfamily M member 8 isoform 1 (mouse)
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mTRPM8/iso:1
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"A transient receptor potential cation channel TRPM8 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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organism-modification
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PR:000036607 |
transient receptor potential cation channel TRPM8 isoform 1 N-glycosylated 1 (mouse)
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mTRPM8/iso:1/NGlyco:1
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"A transient receptor potential cation channel TRPM8 isoform 1 N-glycosylated 1 in mouse. UniProtKB:Q8R4D5-1, Asn-934, MOD:00160." [PMID:17015441, PRO:HJD]
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modification
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PR:000001723 |
transient receptor potential cation channel TRPM8 isoform 1 glycosylated form
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TRPM8/iso:1/GlycoRes+
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"A transient receptor potential cation channel TRPM8 isoform 1 that includes at least one glycosylated residue." [PRO:CNA]
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modification
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PR:000001724 |
transient receptor potential cation channel TRPM8 isoform 1 N-glycosylated 1
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TRPM8/iso:1/NGlyco:1
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"A transient receptor potential cation channel TRPM8 isoform 1 glycosylated form that has been N-glycosylated on the Asn consensus N-glycosylation site within the pore loop region. Example: UniProtKB:Q8R4D5-1, Asn-934, MOD:00160." [PMID:17015441]
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organism-modification
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PR:000036607 |
transient receptor potential cation channel TRPM8 isoform 1 N-glycosylated 1 (mouse)
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mTRPM8/iso:1/NGlyco:1
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"A transient receptor potential cation channel TRPM8 isoform 1 N-glycosylated 1 in mouse. UniProtKB:Q8R4D5-1, Asn-934, MOD:00160." [PMID:17015441, PRO:HJD]
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sequence
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PR:000001721 |
transient receptor potential cation channel TRPM8 isoform 2
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TRPM8/iso:2
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"A transient receptor potential cation channel TRPM8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z2W7-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
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PR:Q7Z2W7-2 |
transient receptor potential cation channel subfamily M member 8 isoform 2 (human)
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hTRPM8/iso:2
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"A transient receptor potential cation channel TRPM8 isoform 2 that is encoded in the genome of human." [PRO:CNA]
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sequence
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PR:000001722 |
transient receptor potential cation channel TRPM8 isoform 3
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TRPM8/iso:3
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"A transient receptor potential cation channel TRPM8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z2W7-3 or a 1:1 ortholog thereof." [PRO:CNA]
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organism-sequence
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PR:Q7Z2W7-3 |
transient receptor potential cation channel subfamily M member 8 isoform 3 (human)
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hTRPM8/iso:3
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"A transient receptor potential cation channel TRPM8 isoform 3 that is encoded in the genome of human." [PRO:CNA]
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