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Protein Ontology report - short transient receptor potential cation channel TRPC2
PR:000001725 - http://purl.obolibrary.org/obo/PR_000001725
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001725   
  PRO nameshort transient receptor potential cation channel TRPC2 
  Synonyms
PRO-Short-label: EXACT:Trpc2
Gene-based: RELATED:Trp2 | Trrp2
Other: EXACT:transient receptor protein 2 | TrpC2
RELATED:TRP-2
  Definition"A transient receptor potential cation channel TRPC that is a translation product of the mouse Trpc2 gene or a 1:1 ortholog thereof. It mediates both receptor- and store depletion-triggered calcium entry. It plays an important role in the transduction machinery underlying the detection of pheromone signals by the vomeronasal organ (VNO), a part of the accessory olfactory system." [PMID:15971083, PMID:17217050] 
  PRO Categorygene 
  ParentPR:000000680 transient receptor potential cation channel TRPC
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 1                                        
         Sequence4                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF501000
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001725 short transient receptor potential cation channel TRPC2
Trpc2

organism-gene


PR:Q9R244 short transient receptor potential channel 2 (mouse)
mTrpc2
Yes
organism-sequence


PR:Q9R244-1 short transient receptor potential channel 2 isoform 1 (mouse)
mTrpc2/iso:1
Yes
organism-sequence


PR:Q9R244-2 short transient receptor potential channel 2 isoform 2 (mouse)
mTrpc2/iso:2
Yes
organism-sequence


PR:Q9R244-3 short transient receptor potential channel 2 isoform 3 (mouse)
mTrpc2/iso:3
Yes
organism-sequence


PR:Q9R244-4 short transient receptor potential channel 2 isoform 4 (mouse)
mTrpc2/iso:4
Yes
sequence


PR:000001726 short transient receptor potential cation channel TRPC2 isoform 1
Trpc2/iso:1

organism-sequence


PR:Q9R244-1 short transient receptor potential channel 2 isoform 1 (mouse)
mTrpc2/iso:1
Yes
sequence


PR:000001727 short transient receptor potential cation channel TRPC2 isoform 2
Trpc2/iso:2

organism-sequence


PR:Q9R244-2 short transient receptor potential channel 2 isoform 2 (mouse)
mTrpc2/iso:2
Yes
sequence


PR:000001728 short transient receptor potential cation channel TRPC2 isoform 3
Trpc2/iso:3

organism-sequence


PR:Q9R244-3 short transient receptor potential channel 2 isoform 3 (mouse)
mTrpc2/iso:3
Yes
sequence


PR:000001729 short transient receptor potential cation channel TRPC2 isoform 4
Trpc2/iso:4

organism-sequence


PR:Q9R244-4 short transient receptor potential channel 2 isoform 4 (mouse)
mTrpc2/iso:4
Yes
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
NOT GO:0015279 store-operated calcium channel activityPR:Q9R244 mTrpc2 PMID:10998353

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0005516 calmodulin bindingPR:Q9R244-1 mTrpc2/iso:1 MGI_ref:2652910; PMID:12601176
PR:Q9R244-2 mTrpc2/iso:2 PMID:12601176

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0000139 Golgi membranePR:Q9R244-3 mTrpc2/iso:3 MGI_ref:1913270; PMID:10998353
PR:Q9R244-4 mTrpc2/iso:4 PMID:10998353
GO:0005635 nuclear envelopePR:Q9R244-3 mTrpc2/iso:3 MGI_ref:1913270; PMID:10998353
PR:Q9R244-4 mTrpc2/iso:4 MGI_ref:1913270; PMID:10998353
GO:0005789 endoplasmic reticulum membranePR:Q9R244-3 mTrpc2/iso:3 MGI_ref:1913270; PMID:10998353
PR:Q9R244-4 mTrpc2/iso:4 MGI_ref:1913270; PMID:10998353