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Protein Ontology report - mitogen-activated protein kinase kinase kinase 7-interacting protein 2/3
PR:000001769 - http://purl.obolibrary.org/obo/PR_000001769
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000001769   
  PRO namemitogen-activated protein kinase kinase kinase 7-interacting protein 2/3 
  Synonyms
PRO-Short-label: EXACT:fam:TAB2-TAB3
  Definition"A protein with core domain architecture consisting of an N-terminal CUE domain (Pfam:PF02845) and a C-terminal zinc-finger domain. TAB2 and TAB3 are receptors that bind preferentially to lysine-linked polyubiquitin chains through the Zn-finger domain." [PMID:15327770, PRO:CNA] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 2                                        
         Gene2                                                  Organism-Gene 6                                        
         Sequence1                                                  Organism-Sequence 9                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF038187
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000001769 mitogen-activated protein kinase kinase kinase 7-interacting protein 2/3
fam:TAB2-TAB3

gene


PR:000001771 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
TAB3

organism-gene


PR:Q571K4 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (mouse)
mTAB3

organism-gene


PR:Q8N5C8 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (human)
hTAB3

organism-sequence


PR:Q8N5C8-1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform h1 (human)
hTAB3/iso:h1

organism-sequence


PR:Q8N5C8-2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform h2 (human)
hTAB3/iso:h2

organism-modification


PR:000049393 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, initiator methionine removed form (human)
hTAB3/InitMet-

gene


PR:000001772 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
TAB2

organism-gene


PR:Q5RFW2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (zebrafish)
z-TAB2

organism-sequence


PR:Q5RFW2-1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform 1 (zebrafish)
z-TAB2/iso:1

organism-sequence


PR:Q5RFW2-2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform 2 (zebrafish)
z-TAB2/iso:2

organism-gene


PR:Q5U303 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (rat)
rTAB2

organism-sequence


PR:Q5U303-1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform 1 (rat)
rTAB2/iso:1

organism-sequence


PR:Q5U303-2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform r2 (rat)
rTAB2/iso:r2

organism-gene


PR:Q99K90 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (mouse)
mTAB2

Yes
organism-sequence


PR:Q99K90-1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform 1 (mouse)
mTAB2/iso:1

organism-gene


PR:Q9NYJ8 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (human)
hTAB2

Yes
organism-sequence


PR:Q9NYJ8-1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform 1 (human)
hTAB2/iso:1

organism-sequence


PR:Q9NYJ8-2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform h2 (human)
hTAB2/iso:h2

organism-modification


PR:000070176 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 cysteinylated 1 (human)
hTAB2/Cyst:1

organism-modification


PR:000081620 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 methylated 1 (human)
hTAB2/Me:1

sequence


PR:000043660 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform 1
TAB2/iso:1

organism-sequence


PR:Q5U303-1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform 1 (rat)
rTAB2/iso:1

organism-sequence


PR:Q99K90-1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform 1 (mouse)
mTAB2/iso:1

organism-sequence


PR:Q9NYJ8-1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform 1 (human)
hTAB2/iso:1

organism-family


PR:000027101 mitogen-activated protein kinase kinase kinase 7-interacting protein 2/3 (mouse)
fam:mTAB2-mTAB3

Yes




PR:Q571K4 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (mouse)





PR:Q99K90 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (mouse)

organism-family


PR:000027103 mitogen-activated protein kinase kinase kinase 7-interacting protein 2/3 (human)
fam:hTAB2-hTAB3

Yes




PR:Q8N5C8 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (human)





PR:Q9NYJ8 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (human)

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fam:TAB2-TAB3 forms found in complexes   

fam:TAB2-TAB3 Component
 Complexes
PR:000027101 fam:mTAB2-mTAB3 PR:000027102 TAK1 kinase complex (mouse)
PR:000036111 K63-poly-Ub-rip1:traf6:TAK1 kinase complex (mouse)
PR:000036114 IkappaB kinase:K63-poly-Ub-rip1:traf6:TAK1 kinase complex (mouse)
PR:000036117 pIKBK:K63-poly-Ub-rip1:traf6:TAK1 kinase complex (mouse)
PR:000027103 fam:hTAB2-hTAB3 PR:000035730 TAK1 kinase complex (human)
PR:000035734 free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
PR:000035738 free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
PR:000035740 free K63-linked pUb:activated TAK1 complex:pUbtraf6 complex (human)
PR:000037342 free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:activated TLR3 complex (human)
PR:Q99K90 mTAB2 PR:000027105 TRIKA2 complex (mouse)
PR:Q9NYJ8 hTAB2 PR:000028440 TAB2/TAK1 complex (human)