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Protein Ontology report - serine/threonine-protein kinase TBK1
PR:000001779 - http://purl.obolibrary.org/obo/PR_000001779
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000001779   
  PRO nameserine/threonine-protein kinase TBK1 
  Synonyms
PRO-Short-label: EXACT:TBK1
Gene-based: RELATED:NAK
Other: EXACT:NF-kappa-B-activating kinase | T2K | TANK-binding kinase 1
  Definition"An IKK-related kinase that is a translation product of the human TBK1 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000001777 IKK-related kinase
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence1                                                  Organism-Sequence 1                                        
         Modification1                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2237
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001779 serine/threonine-protein kinase TBK1
TBK1

organism-gene


PR:Q9UHD2 serine/threonine-protein kinase TBK1 (human)
hTBK1

organism-sequence


PR:Q9UHD2-1 serine/threonine-protein kinase TBK1 isoform 1 (human)
hTBK1/iso:1

organism-modification


PR:000028695 serine/threonine-protein kinase TBK1 phosphorylated 1 (human)
hTBK1/Phos:1

Yes
organism-modification


PR:000045519 serine/threonine-protein kinase TBK1 phosphorylated 2 (human)
hTBK1/Phos:2

organism-modification


PR:000064841 serine/threonine-protein kinase TBK1 phosphorylated and ubiquitinated 1 (human)
hTBK1/PhosUbiq:1

organism-modification


PR:000066943 serine/threonine-protein kinase TBK1 methylated 1 (human)
hTBK1/Me:1

organism-modification


PR:000068123 serine/threonine-protein kinase TBK1 deaminated 1 (human)
hTBK1/Deam:1

organism-modification


PR:000070007 serine/threonine-protein kinase TBK1 cysteinylated 1 (human)
hTBK1/Cyst:1

organism-modification


PR:000075441 serine/threonine-protein kinase TBK1 deaminated 2 (human)
hTBK1/Deam:2

organism-modification


PR:000077131 serine/threonine-protein kinase TBK1 deaminated 3 (human)
hTBK1/Deam:3

organism-gene


PR:Q9WUN2 serine/threonine-protein kinase TBK1 (mouse)
mTBK1

Yes
organism-modification


PR:000080978 serine/threonine-protein kinase TBK1 cysteinylated 1 (mouse)
mTBK1/Cyst:1

sequence


PR:000028692 serine/threonine-protein kinase TBK1 isoform 1
TBK1/iso:1

organism-sequence


PR:Q9UHD2-1 serine/threonine-protein kinase TBK1 isoform 1 (human)
hTBK1/iso:1

modification


PR:000028694 serine/threonine-protein kinase TBK1 phosphorylated 1
TBK1/Phos:1

organism-modification


PR:000028695 serine/threonine-protein kinase TBK1 phosphorylated 1 (human)
hTBK1/Phos:1

Yes
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TBK1 forms found in complexes   

TBK1 Component
 Complexes
PR:000028695 hTBK1/Phos:1 PR:000036030 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036034 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036123 p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human)
PR:000037322 p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037354 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037356 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:Q9WUN2 mTBK1 PR:000036090 tbk1:tank:ikke:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:000036093 tbk1:K63-poly-Ub-tank:Ikke:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:000036097 tbk1:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:000036149 tbk1:tank:ikke complex (mouse)
PR:000037313 tbk1:tank:ikke:traf3:ticam1:activated TLR3 complex (mouse)