|
|
 |
 |
|  |  |
 |  |  |  |  |  |  |  |  |
family
 |


|
 PR:000001781 |
   interleukin-1 receptor-associated kinase IRAK1/3
 |
   IRAK4
 |
  "A protein with core domain architecture consisting of an N-terminal Death domain (Pfam:PF00531) followed by a Protein kinase domain (Pfam:PF00069). This class is closely related to IRAK-4 (PR:000001780), but it contains an extra C-terminal region of about 200 residues." [PMID:12620219]
 |

| 
|
|
|
 |
 |
|  |  |  |  |
 |  |  |  |  |  |  |
gene
 |


|
 PR:000001782 |
   interleukin-1 receptor-associated kinase 1
 |
   IRAK1
 |
  "An interleukin-1 receptor-associated kinase IRAK1/3 that is a translation product of the human IRAK1 gene or a 1:1 ortholog thereof." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |  |
organism-gene
 |


|
 PR:P51617 |
   interleukin-1 receptor-associated kinase 1 (human)
 |
   hIRAK1
 |
  "An interleukin-1 receptor-associated kinase 1 that is encoded in the genome of human." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P51617-1 |
   interleukin-1 receptor-associated kinase 1 isoform 1 (human)
 |
   hIRAK1/iso:1
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000027492 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 (human)
 |
   hIRAK1/iso:1/Phos:3
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 in human. UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047." [PMID:14625308, PRO:CNA]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000027493 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 (human)
 |
   hIRAK1/iso:1/Phos:4
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 in human. UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046." [PMID:14625308, PRO:CNA]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000027494 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (human)
 |
   hIRAK1/iso:1/Phos:1
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 in human. UniProtKB:P51617-1, Thr-209, MOD:00047." [PRO:DNx, UniProtKB:P51617]
 |
 Yes |  Yes |
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000061935 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphoserine and phosphothreonine form (human)
 |
   hIRAK1/iso:1/pSerThr+
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 (human) that includes at least one phosphorylated serine and at least one phosphorylated threonine. UniProtKB:P51617-1, MOD:00046|MOD:00047." [PRO:DNx, Reactome:R-HSA-193904]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P51617-2 |
   interleukin-1 receptor-associated kinase 1 isoform h2 (human)
 |
   hIRAK1/iso:h2
 |
  "An interleukin-1 receptor-associated kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51617-2." [PRO:DNx, UniProtKB:P51617]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P51617-3 |
   interleukin-1 receptor-associated kinase 1 isoform h3 (human)
 |
   hIRAK1/iso:h3
 |
  "An interleukin-1 receptor-associated kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51617-3." [PRO:DNx, UniProtKB:P51617]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P51617-4 |
   interleukin-1 receptor-associated kinase 1 isoform h4 (human)
 |
   hIRAK1/iso:h4
 |
  "An interleukin-1 receptor-associated kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51617-4." [PRO:DNx, UniProtKB:P51617]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
organism-modification
 |


|
 PR:000048042 |
   interleukin-1 receptor-associated kinase 1 phosphorylated 5 (human)
 |
   hIRAK1/Phos:5
 |
  "An interleukin-1 receptor-associated kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-376, and phosphothreonine at position 387 of the amino acid sequence represented by UniProtKB:P51617. UniProtKB:P51617, Ser-376, MOD:00046|Thr-387, MOD:00047." [PRO:DNx, Reactome:R-HSA-446687]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
organism-modification
 |


|
 PR:000048043 |
   interleukin-1 receptor-associated kinase 1 phosphorylated 1 (human)
 |
   hIRAK1/Phos:1
 |
  "An interleukin-1 receptor-associated kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-209 of the amino acid sequence represented by UniProtKB:P51617. UniProtKB:P51617, Thr-209, MOD:00047." [PRO:DNx, Reactome:R-HSA-937031, Reactome:R-HSA-975189]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
organism-modification
 |


|
 PR:000048044 |
   interleukin-1 receptor-associated kinase 1 phosphorylated 3 (human)
 |
   hIRAK1/Phos:3
 |
  "An interleukin-1 receptor-associated kinase 1 (human) that has been post-translationally modified to include phosphothreonine at positions 209 and 387 of the amino acid sequence represented by UniProtKB:P51617. UniProtKB:P51617, Thr-209/Thr-387, MOD:00047." [PRO:DNx, Reactome:R-HSA-166279, Reactome:R-HSA-975117]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
organism-modification
 |


|
 PR:000062298 |
   interleukin-1 receptor-associated kinase 1 phosphorylated 2 (human)
 |
   hIRAK1/Phos:2
 |
  "An interleukin-1 receptor-associated kinase 1 (human) that has been phosphorylated on the residues at the positions equivalent to Thr-209, Ser-376, and Thr-387 of the amino acid sequence represented by UniProtKB:P51617-1 and that includes at least one additional phosphorylated threonine and at least two additional phosphorylated serines. Example: UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|Ser-376, MOD:00046|MOD:00046(2+)|MOD:00047." [PRO:DNx, Reactome:R-HSA-446682, Reactome:R-HSA-937011, Reactome:R-HSA-975157]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
organism-modification
 |


|
 PR:000064197 |
   interleukin-1 receptor-associated kinase 1 phosphoserine and phosphothreonine form (human)
 |
   hIRAK1/pSerThr+
 |
  "An interleukin-1 receptor-associated kinase 1 (human) that includes at least one phosphorylated serine and at least one phosphorylated threonine. UniProtKB:P51617, MOD:00046|MOD:00047." [PRO:DNx, Reactome:R-HSA-3149574]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
organism-modification
 |


|
 PR:000064772 |
   interleukin-1 receptor-associated kinase 1 phosphorylated and ubiquitinated 1 (human)
 |
   hIRAK1/PhosUbiq:1
 |
  "An interleukin-1 receptor-associated kinase 1 (human) that has been phosphorylated on the residues at the positions equivalent to Thr-209, Ser-376 and Thr-387, and ubiquitinated on the residues at the positions equivalent to Lys-134 and Lys-180 of the amino acid sequence represented by UniProtKB:P51617-1 and that includes at least one additional phosphorylated threonine and at least two additional phosphorylated serines. Example: UniProtKB:P51617-1, Lys-134/Lys-180, MOD:01148|Thr-209/Thr-387, MOD:00047|Ser-376, MOD:00046|MOD:00046(2+)|MOD:00047." [PRO:DNx, Reactome:R-HSA-975112]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |  |
organism-gene
 |


|
 PR:Q62406 |
   interleukin-1 receptor-associated kinase 1 (mouse)
 |
   mIRAK1
 |
  "An interleukin-1 receptor-associated kinase 1 that is encoded in the genome of mouse." [OMA:Q62406, PRO:CNA]
 |

|  Yes |
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:Q62406-1 |
   interleukin-1 receptor-associated kinase 1 isoform 1 (mouse)
 |
   mIRAK1/iso:1
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000027178 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (mouse)
 |
   mIRAK1/iso:1/Phos:1
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q62406-1, Thr-209, MOD:00047." [PMID:12538665, TLR:AMM]
 |

|  Yes |
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000027179 |
   interleukin-1 receptor-associated kinase 1 isoform 1 unmodified form (mouse)
 |
   mIRAK1/iso:1/UnMod
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 unmodified form in mouse." [PRO:CNA]
 |

|  Yes |
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:Q62406-2 |
   interleukin-1 receptor-associated kinase 1 isoform m2 (mouse)
 |
   mIRAK1/iso:m2
 |
  "An interleukin-1 receptor-associated kinase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62406-2." [PRO:DNx, UniProtKB:Q62406]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |  |
sequence
 |


|
 PR:000021973 |
   interleukin-1 receptor-associated kinase 1 isoform 1
 |
   IRAK1/iso:1
 |
  "An interleukin-1 receptor-associated kinase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51617-1 or a 1:1 ortholog thereof." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P51617-1 |
   interleukin-1 receptor-associated kinase 1 isoform 1 (human)
 |
   hIRAK1/iso:1
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000027492 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 (human)
 |
   hIRAK1/iso:1/Phos:3
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 in human. UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047." [PMID:14625308, PRO:CNA]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000027493 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 (human)
 |
   hIRAK1/iso:1/Phos:4
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 in human. UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046." [PMID:14625308, PRO:CNA]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000027494 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (human)
 |
   hIRAK1/iso:1/Phos:1
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 in human. UniProtKB:P51617-1, Thr-209, MOD:00047." [PRO:DNx, UniProtKB:P51617]
 |
 Yes |  Yes |
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000061935 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphoserine and phosphothreonine form (human)
 |
   hIRAK1/iso:1/pSerThr+
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 (human) that includes at least one phosphorylated serine and at least one phosphorylated threonine. UniProtKB:P51617-1, MOD:00046|MOD:00047." [PRO:DNx, Reactome:R-HSA-193904]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:Q62406-1 |
   interleukin-1 receptor-associated kinase 1 isoform 1 (mouse)
 |
   mIRAK1/iso:1
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000027178 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (mouse)
 |
   mIRAK1/iso:1/Phos:1
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q62406-1, Thr-209, MOD:00047." [PMID:12538665, TLR:AMM]
 |

|  Yes |
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000027179 |
   interleukin-1 receptor-associated kinase 1 isoform 1 unmodified form (mouse)
 |
   mIRAK1/iso:1/UnMod
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 unmodified form in mouse." [PRO:CNA]
 |

|  Yes |
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
modification
 |


|
 PR:000021971 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated form
 |
   IRAK1/iso:1/PhosRes+
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
 |
modification
 |


|
 PR:000021975 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1
 |
   IRAK1/iso:1/Phos:1
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated form in which the phosphorylation by interleukin-1 receptor-associated kinase 4 (IRAK-4) occurs on the conserved Thr residue (Thr-209 in human) located at the N terminus of the kinase domain. This is the first step following the activation of the TLR/IL-1 receptor complex. This phosphorylation results in a conformational change of the kinase domain. Example: UniProtKB:P51617-1, Thr-209, MOD:00047." [PMID:11960013, PMID:14625308, PRO:CNA, TLR:AMM]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |  |  |
organism-modification
 |


|
 PR:000027178 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (mouse)
 |
   mIRAK1/iso:1/Phos:1
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q62406-1, Thr-209, MOD:00047." [PMID:12538665, TLR:AMM]
 |

|  Yes |
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |  |  |
organism-modification
 |


|
 PR:000027494 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (human)
 |
   hIRAK1/iso:1/Phos:1
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 in human. UniProtKB:P51617-1, Thr-209, MOD:00047." [PRO:DNx, UniProtKB:P51617]
 |
 Yes |  Yes |
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
 |
modification
 |


|
 PR:000021977 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3
 |
   IRAK1/iso:1/Phos:3
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated form in which the phosphorylation by interleukin-1 receptor-associated kinase 4 (IRAK-4) occurs on the conserved Thr residue (Thr-209 in human) located near the N terminus of the kinase domain, and on a Thr residue located in the activation loop (Thr-387 in human). The latter phosphorylation is the second step following the activation of the TLR/IL-1 receptor complex. Example: UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047." [PMID:14625308, PRO:CNA, PRO:DAN]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |  |  |
organism-modification
 |


|
 PR:000027492 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 (human)
 |
   hIRAK1/iso:1/Phos:3
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 in human. UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047." [PMID:14625308, PRO:CNA]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
 |
modification
 |


|
 PR:000021978 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4
 |
   IRAK1/iso:1/Phos:4
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated form in which the phosphorylation occurs by interleukin-1 receptor-associated kinase 4 (IRAK-4) and extensively autophosphorylated in the Pro-, Ser-, and Thr-rich ProST region between the N-terminal death domain and kinase domain. Example: UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046." [PMID:14625308, PRO:CNA, PRO:DAN]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |  |  |
organism-modification
 |


|
 PR:000027493 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 (human)
 |
   hIRAK1/iso:1/Phos:4
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 in human. UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046." [PMID:14625308, PRO:CNA]
 |
 Yes | 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000061935 |
   interleukin-1 receptor-associated kinase 1 isoform 1 phosphoserine and phosphothreonine form (human)
 |
   hIRAK1/iso:1/pSerThr+
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 (human) that includes at least one phosphorylated serine and at least one phosphorylated threonine. UniProtKB:P51617-1, MOD:00046|MOD:00047." [PRO:DNx, Reactome:R-HSA-193904]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
modification
 |


|
 PR:000021974 |
   interleukin-1 receptor-associated kinase 1 isoform 1 unmodified form
 |
   IRAK1/iso:1/UnMod
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000027179 |
   interleukin-1 receptor-associated kinase 1 isoform 1 unmodified form (mouse)
 |
   mIRAK1/iso:1/UnMod
 |
  "An interleukin-1 receptor-associated kinase 1 isoform 1 unmodified form in mouse." [PRO:CNA]
 |

|  Yes |
|
|
 |
 |
|  |  |  |  |
 |  |  |  |  |  |  |
gene
 |


|
 PR:000001783 |
   interleukin-1 receptor-associated kinase-like 2
 |
   IRAK2
 |
  "An interleukin-1 receptor-associated kinase IRAK1/3 that is a translation product of the human IRAK2 gene or a 1:1 ortholog thereof. This protein class is inactive as a kinase due to a change of an Asn instead of an Asp redisue in a catalytic site." [PMID:9374458, PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |  |
organism-gene
 |


|
 PR:F1N826 |
   uncharacterized protein, IRAK2 translation product (chicken)
 |
   chick-IRAK2
 |
  "An interleukin-1 receptor-associated kinase-like 2 that is encoded in the genome of chicken." [OMA:F1N826, PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |  |
organism-gene
 |


|
 PR:O43187 |
   interleukin-1 receptor-associated kinase-like 2 (human)
 |
   hIRAK2
 |
  "An interleukin-1 receptor-associated kinase-like 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:O43187]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
organism-modification
 |


|
 PR:000048045 |
   interleukin-1 receptor-associated kinase-like 2 phosphorylated form (human)
 |
   hIRAK2/PhosRes+
 |
  "An interleukin-1 receptor-associated kinase-like 2 (human) that includes at least one phosphorylated residue. UniProtKB:O43187, MOD:00696." [PRO:DNx, Reactome:R-HSA-446636, Reactome:R-HSA-936949, Reactome:R-HSA-975187]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
organism-modification
 |


|
 PR:000081167 |
   interleukin-1 receptor-associated kinase-like 2 cysteinylated 1 (human)
 |
   hIRAK2/Cyst:1
 |
  "An interleukin-1 receptor-associated kinase-like 2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-470 of the amino acid sequence represented by UniProtKB:O43187. UniProtKB:O43187, Cys-470, MOD:00765." [IEDB_epitope:1578132, PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |  |
organism-modification
 |


|
 PR:000081833 |
   interleukin-1 receptor-associated kinase-like 2 cysteinylated 2 (human)
 |
   hIRAK2/Cyst:2
 |
  "An interleukin-1 receptor-associated kinase-like 2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-261 of the amino acid sequence represented by UniProtKB:O43187. UniProtKB:O43187, Cys-261, MOD:00765." [IEDB_epitope:1857096, PRO:DNx]
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organism-modification
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 PR:000082521 |
   interleukin-1 receptor-associated kinase-like 2 cysteinylated 3 (human)
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   hIRAK2/Cyst:3
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  "An interleukin-1 receptor-associated kinase-like 2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-79 of the amino acid sequence represented by UniProtKB:O43187. UniProtKB:O43187, Cys-79, MOD:00765." [IEDB_epitope:1333187, PRO:DNx]
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organism-gene
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 PR:Q4QQS0 |
   interleukin-1 receptor-associated kinase-like 2 (rat)
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   rIRAK2
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  "An interleukin-1 receptor-associated kinase-like 2 that is encoded in the genome of rat." [OMA:Q4QQS0, PRO:DNx]
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organism-gene
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 PR:Q8CFA1 |
   interleukin-1 receptor-associated kinase-like 2 (mouse)
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   mIRAK2
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  "An interleukin-1 receptor-associated kinase-like 2 that is encoded in the genome of mouse." [OMA:Q8CFA1, PRO:DNx]
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organism-sequence
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 PR:Q8CFA1-1 |
   interleukin-1 receptor-associated kinase-like 2 isoform m1 (mouse)
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   mIRAK2/iso:m1
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  "An interleukin-1 receptor-associated kinase-like 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CFA1-1." [PRO:DNx, UniProtKB:Q8CFA1]
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organism-sequence
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 PR:Q8CFA1-2 |
   interleukin-1 receptor-associated kinase-like 2 isoform m2 (mouse)
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   mIRAK2/iso:m2
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  "An interleukin-1 receptor-associated kinase-like 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CFA1-2." [PRO:DNx, UniProtKB:Q8CFA1]
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organism-sequence
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 PR:Q8CFA1-3 |
   interleukin-1 receptor-associated kinase-like 2 isoform m3 (mouse)
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   mIRAK2/iso:m3
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  "An interleukin-1 receptor-associated kinase-like 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CFA1-3." [PRO:DNx, UniProtKB:Q8CFA1]
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organism-sequence
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 PR:Q8CFA1-4 |
   interleukin-1 receptor-associated kinase-like 2 isoform m4 (mouse)
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   mIRAK2/iso:m4
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  "An interleukin-1 receptor-associated kinase-like 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CFA1-4." [PRO:DNx, UniProtKB:Q8CFA1]
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gene
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 PR:000001784 |
   interleukin-1 receptor-associated kinase 3
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   IRAK3
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  "An interleukin-1 receptor-associated kinase IRAK1/3 that is a translation product of the human IRAK3 gene or a 1:1 ortholog thereof." [PMID:12150927, PRO:CNA]
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organism-gene
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 PR:Q8K4B2 |
   interleukin-1 receptor-associated kinase 3 (mouse)
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   mIRAK3
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  "An interleukin-1 receptor-associated kinase 3 that is encoded in the genome of mouse." [OMA:Q8K4B2, PMID:12150927, PRO:CNA]
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 Yes |  Yes |
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organism-gene
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 PR:Q9Y616 |
   interleukin-1 receptor-associated kinase 3 (human)
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   hIRAK3
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  "An interleukin-1 receptor-associated kinase 3 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9Y616]
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organism-sequence
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 PR:Q9Y616-1 |
   interleukin-1 receptor-associated kinase 3 isoform 1 (human)
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   hIRAK3/iso:1
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  "An interleukin-1 receptor-associated kinase 3 isoform 1 that is encoded in the genome of human." [GenBank:AF113136, PMID:10383454, PRO:CNA]
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 Yes | 
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organism-sequence
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 PR:Q9Y616-2 |
   interleukin-1 receptor-associated kinase 3 isoform h2 (human)
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   hIRAK3/iso:h2
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  "An interleukin-1 receptor-associated kinase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y616-2." [PRO:DNx, UniProtKB:Q9Y616]
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organism-modification
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 PR:000073219 |
   interleukin-1 receptor-associated kinase 3 phosphorylated 1 (human)
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   hIRAK3/Phos:1
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  "An interleukin-1 receptor-associated kinase 3 (human) that has been phosphorylated on the residue at the position equivalent to Ser-335 of the amino acid sequence represented by UniProtKB:Q9Y616-1. Example: UniProtKB:Q9Y616-1, Ser-335, MOD:00046." [IEDB_epitope:912152, PRO:DNx]
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sequence
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|
 PR:000027241 |
   interleukin-1 receptor-associated kinase 3 isoform 1
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   IRAK3/iso:1
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  "An interleukin-1 receptor-associated kinase 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y616-1 or a 1:1 ortholog thereof." [GenBank:AF113136, PMID:10383454, PRO:CNA]
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organism-sequence
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 PR:Q9Y616-1 |
   interleukin-1 receptor-associated kinase 3 isoform 1 (human)
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   hIRAK3/iso:1
 |
  "An interleukin-1 receptor-associated kinase 3 isoform 1 that is encoded in the genome of human." [GenBank:AF113136, PMID:10383454, PRO:CNA]
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 Yes | 
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