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Protein Ontology report - PR domain zinc finger protein 1
PR:000001831 - http://purl.obolibrary.org/obo/PR_000001831
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001831   
  PRO namePR domain zinc finger protein 1 
  Synonyms
PRO-Short-label: EXACT:PRDM1
Gene-based: RELATED:BLIMP1
Other: EXACT:beta-interferon gene positive regulatory domain I-binding factor | BLIMP-1 | positive regulatory domain I-binding factor 1 | PR domain-containing protein 1 | PRDI-BF1 | PRDI-binding factor 1
  Definition"A protein that is a translation product of the human PRDM1 gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence2                                                  Organism-Sequence 9                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF013212
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001831
PR domain zinc finger protein 1
PRDM1
"A protein that is a translation product of the human PRDM1 gene or a 1:1 ortholog thereof." [PRO:WCB]

organism-gene


PR:O75626
PR domain zinc finger protein 1 (human)
hPRDM1
"A PR domain zinc finger protein 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:O75626]

organism-sequence


PR:O75626-1
PR domain zinc finger protein 1 isoform 1 (human)
hPRDM1/iso:1
"A PR domain zinc finger protein 1 isoform 2 that is encoded in the genome of human." [PRO:CNA]

organism-sequence


PR:O75626-2
PR domain zinc finger protein 1 isoform h2 (human)
hPRDM1/iso:h2
"A PR domain zinc finger protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75626-2." [PRO:DNx, UniProtKB:O75626]

organism-sequence


PR:O75626-3
PR domain zinc finger protein 1 isoform h3 (human)
hPRDM1/iso:h3
"A PR domain zinc finger protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75626-3." [PRO:DNx, UniProtKB:O75626]

organism-modification


PR:000066112
PR domain zinc finger protein 1 cysteinylated 1 (human)
hPRDM1/Cyst:1
"A PR domain zinc finger protein 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-700 of the amino acid sequence represented by UniProtKB:O75626-1. Example: UniProtKB:O75626-1, Cys-700, MOD:00765." [IEDB_epitope:926555, PRO:DNx]

organism-gene


PR:Q60636
PR domain zinc finger protein 1 (mouse)
mPRDM1
"A PR domain zinc finger protein 1 that is encoded in the genome of mouse." [OMA:Q60636, PRO:DNx]

organism-sequence


PR:Q60636-1
PR domain zinc finger protein 1 isoform 1 (mouse)
mPRDM1/iso:1
"A PR domain zinc finger protein 1 isoform 1 that is encoded in the genome of mouse." [PMID:8168136, PRO:HJD]
Yes
organism-sequence


PR:Q60636-2
PR domain zinc finger protein 1 isoform 2 (mouse)
mPRDM1/iso:2
"A PR domain zinc finger protein 1 isoform 2 that is encoded in the genome of mouse." [PMID:16141072, PRO:HJD]
Yes
organism-sequence


PR:Q60636-3
PR domain zinc finger protein 1 isoform m3 (mouse)
mPRDM1/iso:m3
"A PR domain zinc finger protein 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q60636-3." [PRO:DNx, UniProtKB:Q60636]

organism-sequence


PR:Q60636-4
PR domain zinc finger protein 1 isoform m4 (mouse)
mPRDM1/iso:m4
"A PR domain zinc finger protein 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q60636-4." [PRO:DNx, UniProtKB:Q60636]

organism-sequence


PR:Q60636-5
PR domain zinc finger protein 1 isoform m5 (mouse)
mPRDM1/iso:m5
"A PR domain zinc finger protein 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q60636-5." [PRO:DNx, UniProtKB:Q60636]

sequence


PR:000026008
PR domain zinc finger protein 1 isoform 1
PRDM1/iso:1
"A PR domain zinc finger protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q60636-1 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:D4A1S2
PR domain zinc finger protein 1 isoform 1 (rat)
rPRDM1/iso:1
"A PR domain zinc finger protein 1 isoform 1 that is encoded in the genome of rat." [PMID:15632090, PRO:CNA]

organism-sequence


PR:Q60636-1
PR domain zinc finger protein 1 isoform 1 (mouse)
mPRDM1/iso:1
"A PR domain zinc finger protein 1 isoform 1 that is encoded in the genome of mouse." [PMID:8168136, PRO:HJD]
Yes
sequence


PR:000026009
PR domain zinc finger protein 1 isoform 2
PRDM1/iso:2
"A PR domain zinc finger protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q60636-2 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:O75626-1
PR domain zinc finger protein 1 isoform 1 (human)
hPRDM1/iso:1
"A PR domain zinc finger protein 1 isoform 2 that is encoded in the genome of human." [PRO:CNA]

organism-sequence


PR:Q60636-2
PR domain zinc finger protein 1 isoform 2 (mouse)
mPRDM1/iso:2
"A PR domain zinc finger protein 1 isoform 2 that is encoded in the genome of mouse." [PMID:16141072, PRO:HJD]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q60636-1 mPRDM1/iso:1 acts_upstream_of_or_withinGO:0030889 negative regulation of B cell proliferation MGI_ref:3826899; PMID:18845144
GO:0045579 positive regulation of B cell differentiation MGI_ref:3826899; PMID:18845144
enablesGO:0005515 protein binding with PR:Q60636-1 MGI_ref:3826899; PMID:18845144
GO:0005515 protein binding with PR:Q60636-2 MGI_ref:3826899; PMID:18845144
GO:0042826 histone deacetylase binding MGI_ref:3826899; PMID:18845144
GO:0043565 sequence-specific DNA binding MGI_ref:3826899; PMID:18845144
located_inGO:0005634 nucleus MGI_ref:3826899; PMID:18845144
PR:Q60636-2 mPRDM1/iso:2 acts_upstream_of_or_withinGO:0000122 negative regulation of transcription by RNA polymerase II MGI_ref:3826899; PMID:18845144
GO:0030889 negative regulation of B cell proliferation MGI_ref:3826899; PMID:18845144
GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway MGI_ref:3826899; PMID:18845144
NOT GO:0045579 positive regulation of B cell differentiation MGI_ref:3826899; PMID:18845144
enablesGO:0005515 protein binding with PR:Q60636-1 MGI_ref:3826899; PMID:18845144
GO:0005515 protein binding with PR:Q60636-2 MGI_ref:3826899; PMID:18845144
GO:0042826 histone deacetylase binding MGI_ref:3826899; PMID:18845144
located_inGO:0005737 cytoplasm MGI_ref:3826899; PMID:18845144