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Protein Ontology report - leptin receptor
PR:000001875 - http://purl.obolibrary.org/obo/PR_000001875
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001875   
  PRO nameleptin receptor 
  Synonyms
PRO-Short-label: EXACT:LEPR
Gene-based: RELATED:DB | OBR
Other: EXACT:B219 | CD295 | LEP-R | OB receptor | OB-R
  Definition"A protein that is a translation product of the human LEPR gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence3                                                  Organism-Sequence 16                                        
         Modification1                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF018116;IUPHARobj:1712
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000001875

leptin receptor

LEPR


"A protein that is a translation product of the human LEPR gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:P48356

leptin receptor (mouse)

mLEPR


"A leptin receptor that is encoded in the genome of mouse." [OMA:P48356, PRO:DNx]


organism-sequence



PR:P48356-1

leptin receptor isoform B (mouse)

mLEPR/iso:B


"A leptin receptor isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:P48356-2

leptin receptor isoform A (mouse)

mLEPR/iso:A


"A leptin receptor isoform 2 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:P48356-3

leptin receptor isoform C (mouse)

mLEPR/iso:C


"A leptin receptor (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48356-3." [PRO:DNx, UniProtKB:P48356]


organism-sequence



PR:P48356-4

leptin receptor isoform D (mouse)

mLEPR/iso:D


"A leptin receptor (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48356-4." [PRO:DNx, UniProtKB:P48356]


organism-sequence



PR:P48356-5

leptin receptor isoform E (mouse)

mLEPR/iso:E


"A leptin receptor isoform E that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:P48357

leptin receptor (human)

hLEPR


"A leptin receptor that is encoded in the genome of human." [PRO:WCB, UniProtKB:P48357]


organism-sequence



PR:P48357-1

leptin receptor isoform B (human)

hLEPR/iso:B


"A leptin receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48357-1." [PRO:DNx, UniProtKB:P48357]


organism-modification



PR:000062707

leptin receptor isoform B, signal peptide removed form (human)

hLEPR/iso:B/SigPep-


"A leptin receptor isoform B (human) that has had the signal peptide removed. UniProtKB:P48357-1, 22-1165." [PRO:DNx, Reactome:R-HSA-2586526]


organism-modification



PR:000064049

leptin receptor isoform B, signal peptide removed phosphorylated 1 (human)

hLEPR/iso:B/SigPep-/Phos:1


"A leptin receptor isoform B (human) that has had the signal peptide removed and that has been phosphorylated on the residues at the positions equivalent to Tyr-986, Tyr-1079, and Tyr-1141 of the amino acid sequence represented by UniProtKB:P48357-1. UniProtKB:P48357-1, 22-1165, Tyr-986/Tyr-1079/Tyr-1141, MOD:00048." [PRO:DNx, Reactome:R-HSA-2586513]


organism-sequence



PR:P48357-2

leptin receptor isoform A (human)

hLEPR/iso:A


"A leptin receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48357-2." [PRO:DNx, UniProtKB:P48357]


organism-sequence



PR:P48357-3

leptin receptor isoform C (human)

hLEPR/iso:C


"A leptin receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48357-3." [PRO:DNx, UniProtKB:P48357]


organism-sequence



PR:P48357-4

leptin receptor isoform D (human)

hLEPR/iso:D


"A leptin receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48357-4." [PRO:DNx, UniProtKB:P48357]


organism-sequence



PR:P48357-5

leptin receptor isoform E (human)

hLEPR/iso:E


"A leptin receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48357-5." [PRO:DNx, UniProtKB:P48357]


organism-modification



PR:000068258

leptin receptor cysteinylated 1 (human)

hLEPR/Cyst:1


"A leptin receptor (human) that has been cysteinylated on the residue at the position equivalent to Cys-102 of the amino acid sequence represented by UniProtKB:P48357-1. Example: UniProtKB:P48357-1, Cys-102, MOD:00765." [IEDB_epitope:2117863, PRO:DNx]


organism-modification



PR:000081227

leptin receptor cysteinylated 2 (human)

hLEPR/Cyst:2


"A leptin receptor (human) that has been cysteinylated on the residue at the position equivalent to Cys-447 of the amino acid sequence represented by UniProtKB:P48357-1. Example: UniProtKB:P48357-1, Cys-447, MOD:00765." [IEDB_epitope:2125191, PRO:DNx]


organism-modification



PR:000081693

leptin receptor cysteinylated 3 (human)

hLEPR/Cyst:3


"A leptin receptor (human) that has been cysteinylated on the residue at the position equivalent to Cys-604 of the amino acid sequence represented by UniProtKB:P48357-1. Example: UniProtKB:P48357-1, Cys-604, MOD:00765." [IEDB_epitope:2118066, PRO:DNx]


organism-gene



PR:Q62959

leptin receptor (rat)

rLEPR


"A leptin receptor that is encoded in the genome of rat." [OMA:Q62959, PRO:DNx]


organism-sequence



PR:Q62959-1

leptin receptor isoform B (rat)

rLEPR/iso:B


"A leptin receptor isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:Q62959-2

leptin receptor isoform A (rat)

rLEPR/iso:A


"A leptin receptor isoform 2 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:Q62959-3

leptin receptor isoform C (rat)

rLEPR/iso:C


"A leptin receptor (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62959-3." [PRO:DNx, UniProtKB:Q62959]


organism-sequence



PR:Q62959-4

leptin receptor isoform E (rat)

rLEPR/iso:E


"A leptin receptor isoform E that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:Q62959-5

leptin receptor isoform F (rat)

rLEPR/iso:F


"A leptin receptor (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62959-5." [PRO:DNx, UniProtKB:Q62959]


organism-sequence



PR:Q62959-6

leptin receptor isoform D (rat)

rLEPR/iso:D


"A leptin receptor (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62959-6." [PRO:DNx, UniProtKB:Q62959]


sequence



PR:000039538

leptin receptor isoform 1

LEPR/iso:1


"A leptin receptor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48356-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P48356-1

leptin receptor isoform B (mouse)

mLEPR/iso:B


"A leptin receptor isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:Q62959-1

leptin receptor isoform B (rat)

rLEPR/iso:B


"A leptin receptor isoform 1 that is encoded in the genome of rat." [PRO:DNx]


sequence



PR:000039539

leptin receptor isoform 2

LEPR/iso:2


"A leptin receptor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48356-2 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P48356-2

leptin receptor isoform A (mouse)

mLEPR/iso:A


"A leptin receptor isoform 2 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:Q62959-2

leptin receptor isoform A (rat)

rLEPR/iso:A


"A leptin receptor isoform 2 that is encoded in the genome of rat." [PRO:DNx]


sequence



PR:000039540

leptin receptor isoform E

LEPR/iso:E


"A leptin receptor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48356-5 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P48356-5

leptin receptor isoform E (mouse)

mLEPR/iso:E


"A leptin receptor isoform E that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:Q62959-4

leptin receptor isoform E (rat)

rLEPR/iso:E


"A leptin receptor isoform E that is encoded in the genome of rat." [PRO:DNx]


modification



PR:000018565

leptin receptor, signal peptide removed form

LEPR/SigPep-


"A leptin receptor that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000062707

leptin receptor isoform B, signal peptide removed form (human)

hLEPR/iso:B/SigPep-


"A leptin receptor isoform B (human) that has had the signal peptide removed. UniProtKB:P48357-1, 22-1165." [PRO:DNx, Reactome:R-HSA-2586526]


organism-modification



PR:000064049

leptin receptor isoform B, signal peptide removed phosphorylated 1 (human)

hLEPR/iso:B/SigPep-/Phos:1


"A leptin receptor isoform B (human) that has had the signal peptide removed and that has been phosphorylated on the residues at the positions equivalent to Tyr-986, Tyr-1079, and Tyr-1141 of the amino acid sequence represented by UniProtKB:P48357-1. UniProtKB:P48357-1, 22-1165, Tyr-986/Tyr-1079/Tyr-1141, MOD:00048." [PRO:DNx, Reactome:R-HSA-2586513]