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Protein Ontology report - tumor necrosis factor receptor superfamily member 9
PR:000001965 - http://purl.obolibrary.org/obo/PR_000001965
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001965   
  PRO nametumor necrosis factor receptor superfamily member 9 
  Synonyms
PRO-Short-label: EXACT:TNFRSF9
Gene-based: RELATED:CD137 | ILA | Ly63
Other: EXACT:4-1BB ligand receptor | CDw137 | T-cell antigen 4-1BB | T-cell antigen 4-1BB homolog | T-cell antigen ILA
  Definition"A protein that is a translation product of the human TNFRSF9 gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence2                                                  Organism-Sequence 2                                        
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF038814;IUPHARobj:1878
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000001965

tumor necrosis factor receptor superfamily member 9

TNFRSF9


"A protein that is a translation product of the human TNFRSF9 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:P20334

tumor necrosis factor receptor superfamily member 9 (mouse)

mTNFRSF9


"A tumor necrosis factor receptor superfamily member 9 that is encoded in the genome of mouse." [OMA:P20334, PRO:DNx]


organism-sequence



PR:P20334-1

tumor necrosis factor receptor superfamily member 9 isoform 1 (mouse)

mTNFRSF9/iso:1


"A tumor necrosis factor receptor superfamily member 9 isoform 1 that is encoded in the genome of mouse." [PMID:18640726, PRO:KRC]

Yes

organism-sequence



PR:Q8R037

tumor necrosis factor receptor superfamily member 9 isoform 2 (mouse)

mTNFRSF9/iso:2


"A tumor necrosis factor receptor superfamily member 9 isoform 2 that is encoded in the genome of mouse." [PMID:18640726, PRO:KRC]

Yes

Yes
organism-gene



PR:Q07011

tumor necrosis factor receptor superfamily member 9 (human)

hTNFRSF9


"A tumor necrosis factor receptor superfamily member 9 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q07011]


organism-modification



PR:000064610

tumor necrosis factor receptor superfamily member 9, signal peptide removed form (human)

hTNFRSF9/SigPep-


"A tumor necrosis factor receptor superfamily member 9 (human) that has had the signal peptide removed. UniProtKB:Q07011, 24-255." [PRO:DNx, Reactome:R-HSA-5666996]


organism-modification



PR:000074131

tumor necrosis factor receptor superfamily member 9 deaminated 1 (human)

hTNFRSF9/Deam:1


"A tumor necrosis factor receptor superfamily member 9 (human) that has been deaminated on the residue at the position equivalent to Gln-226 of the amino acid sequence represented by UniProtKB:Q07011. UniProtKB:Q07011, Gln-226, MOD:00685." [IEDB_epitope:1776893, IEDB_epitope:1816894, PRO:DNx]


sequence



PR:000035645

tumor necrosis factor receptor superfamily member 9 isoform 1

TNFRSF9/iso:1


"A tumor necrosis factor receptor superfamily member 9 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20334-1 or a 1:1 ortholog thereof." [PRO:KRC]


organism-sequence



PR:P20334-1

tumor necrosis factor receptor superfamily member 9 isoform 1 (mouse)

mTNFRSF9/iso:1


"A tumor necrosis factor receptor superfamily member 9 isoform 1 that is encoded in the genome of mouse." [PMID:18640726, PRO:KRC]

Yes

sequence



PR:000035647

tumor necrosis factor receptor superfamily member 9 isoform 2

TNFRSF9/iso:2


"A tumor necrosis factor receptor superfamily member 9 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8R037 or a 1:1 ortholog thereof." [PRO:KRC]


organism-sequence



PR:Q8R037

tumor necrosis factor receptor superfamily member 9 isoform 2 (mouse)

mTNFRSF9/iso:2


"A tumor necrosis factor receptor superfamily member 9 isoform 2 that is encoded in the genome of mouse." [PMID:18640726, PRO:KRC]

Yes

Yes
modification



PR:000018624

tumor necrosis factor receptor superfamily member 9, signal peptide removed form

TNFRSF9/SigPep-


"A tumor necrosis factor receptor superfamily member 9 that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000064610

tumor necrosis factor receptor superfamily member 9, signal peptide removed form (human)

hTNFRSF9/SigPep-


"A tumor necrosis factor receptor superfamily member 9 (human) that has had the signal peptide removed. UniProtKB:Q07011, 24-255." [PRO:DNx, Reactome:R-HSA-5666996]


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TNFRSF9 forms found in complexes   

TNFRSF9 Component
Complexes
PR:Q8R037 mTNFRSF9/iso:2 PR:000035755 tumor necrosis factor receptor superfamily member 9 isoform 2 homotrimer (mouse)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P20334-1 mTNFRSF9/iso:1 located_inGO:0009897 external side of plasma membrane MGI_ref:3807131; PMID:18640726
PR:Q8R037 mTNFRSF9/iso:2 acts_upstream_of_or_withinGO:0032693 negative regulation of interleukin-10 production MGI_ref:3807131; PMID:18640726
GO:0032695 negative regulation of interleukin-12 production MGI_ref:3807131; PMID:18640726
GO:0070207 protein homotrimerization MGI_ref:3807131; PMID:18640726
located_inGO:0005615 extracellular space MGI_ref:3807131; PMID:18640726